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Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease

  • 1st Edition - April 28, 2026
  • Latest edition
  • Editors: Zahra Keshavarz Motamed, Jose M. de La Torre Hernández, Philippe Pibarot
  • Language: English

Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease explains how abnormal hemodynamics (blood… Read more

Description

Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease explains how abnormal hemodynamics (blood flow dynamics) greatly alter the cardiovascular system’s ability to transport, control and maintain blood flow throughout the body. These deviations often lead to the initiation and progression of disease. Notably, hemodynamic quantification can be extremely useful for accurate and early diagnosis of cardiovascular disease. Particularly, the ability to monitor and predict hemodynamic effects following specific interventions can significantly broaden lifesaving options. However, image-based computational modelling of predictive hemodynamics analysis methods (and therefore new diagnostic tools) are rare. By extending quantitative methods of analysis, medical professionals can foresee effects of various cardiovascular interventions, allowing for optimized, situation-based care.

Advances in Blood Flow Quantification Methods for Diagnosis, Monitoring, Prediction, and Personalized Treatment of Cardiovascular Disease posits that novel, image-based computational modelling hemodynamic analysis tools will enable the next generation of diagnosis, predictive, and treatment planning resources for cardiovascular disease. Readers will become well-versed in recent advances in hemodynamic approaches, while preparing themselves for the next wave of revolutions in cardiovascular health.

Key features

  • Presents a comprehensive integration of cardiovascular disease within the context of hemodynamics
  • Delves into the latest advanced diagnostic and predictive tools to leverage hemodynamics for cardiovascular disease diagnosis and prediction
  • Emphasizes the application of hemodynamics in creating personalized treatment plans and interventions, exploring how individualized data-driven insights can guide therapeutic decisions and interventions

Readership

Cardiologists, Interventional cardiologists, Radiologists, Surgeons, Researchers and academics, Manufacturers of medical devices

Table of contents

  1. Introduction
    Zahra Keshavarz‑Motamed, Philippe Pibarot, Jose M. de La Torre Hernández
  2. Hemodynamics: Fundamentals and roles in atrial fibrillation
    Ahmad Bshennaty, Mohamad Alkhouli, Hoda Hatoum
  3. Advances in blood flow quantification methods for diagnosis and monitoring of cardiovascular disease
    Houriehsadat Jamalidinan, Kavithra Karalasingham, Julio Garcia
  4. Advances in blood flow quantification methods for prediction of cardiovascular interventions
    Tsung‑Ying Tsai, Patrick Serruys, Eric K.W. Poon
  5. Computational predictive modeling of valve performance and risks toward personalization of TAVR with lifetime management
    Taylor Becker, Lakshmi Prasad Dasi
  6. Advances in 4D flow MRI blood flow quantification methods for prediction of cardiovascular intervention
    Alejandro Roldán‑Alzate
  7. Advancing clinical interventions through patient‑specific in‑vitro simulators: Challenges, techniques and future directions
    Seyedvahid Khodaei, MohammadAli Daeian, Nima Maftoon, Zahra Keshavarz‑Motamed
  8. Enhancing patient management with TAVR and coronary disease through computational modeling
    Seyedvahid Khodaei, MohammadAli Daeian, Zahra Keshavarz‑Motamed
  9. Impact of flow in assessment and prognosis of valvular heart diseases
    Marie‑Annick Clavel, Kathia Abdoun, Paolo Springhetti, Andreanne Powers
  10. Translational machine learning in cardiac disease: Advancing diagnosis, monitoring, and prediction
    Yueqing Sun, Zahra Keshavarz‑Motamed
  11. Bridging the critical gap in cardiovascular biomechanics: From computational models to clinical applications
    Seyedvahid Khodaei, Zahra Keshavarz‑Motamed

Product details

  • Edition: 1
  • Latest edition
  • Published: April 28, 2026
  • Language: English

About the editors

ZM

Zahra Keshavarz Motamed

Dr. Zahra K. Motamed PhD, MSc, directs the Cardiovascular Research Group and is an Associate Professor in the Department of Mechanical Engineering at McMaster University. She is a member of the Professional Engineers of Ontario, with over 17 years of experience in cardiovascular diseases and their devices. She served as the Chair of the 2021 NSERC Research Tool and Instruments Selection Committee for Mechanical Engineering. She is on the editorial board of Scientific Reports, and for the Journal of Frontiers in Bioengineering and Biotechnology.

She was a handling Editor in Frontiers in Cardiovascular Medicine. She is currently the invited lead guest editor of Frontiers in Bioengineering and Biotechnology, and an invited guest editor of Scientific Reports (a Nature journal). Her research interests are mainly in the areas of computational fluid dynamics for the study of cardiovascular disease, translational and basic cardiovascular mechanics, and developing quantitative diagnostic, predictive, and intervention-optimization tools.

Affiliations and expertise
Associate Professor, Department of Mechanical Engineering, McMaster University, Canada

Jd

Jose M. de La Torre Hernández

Jose M. de La Torre Hernández MD, PhD, FESC is an interventional cardiologist and head of the Hemodynamics and Interventional Department of the Marques de Valdecilla University of Santander. He is the president of the Spanish Society of Cardiology, and is a fellow of the European Society of Cardiology. Dr. Hernández is the former associate director of the Trans Catheter Therapeutics and TCT conferences (USA).

Dr. Hernández has participated in over 75 clinical trials for cardiac devices and has been an author in more than 220 peer-reviewed papers and 7 book chapters. Dr. Hernández currently serves as the Founder and Editor in Chief of REC: Interventional Cardiology, editorial consultant in JACC Interventions and section editor in Eurointervention. Dr. Hernández brings a vast clinical insight essential to the success of this book, specifically in terms of future clinical device adoptability.

Affiliations and expertise
Hospital Universitario Marques de Valdecilla, Spain

PP

Philippe Pibarot

Philippe Pibarot, DVM, PhD, FACC, FAHA, FASE, FESC, FCCS is a professor in the Department of Medicine at Laval University, holds the Canada Research Chair in Valvular Heart Disease, and is head of Cardiology Research at Québec Heart & Lung Institute (IUCPQ). He is principal investigator in studies and trials funded by a grant from the Canadian Institutes of Health Research, and directs the Echocardiography Core Laboratory at IUCPQ.

He is associate editor for the Structural Heart and Eurointervention journals, Imaging section editor for the Journal of the American College of Cardiology, and Editor-in-Chief of the Journal of the Heart Valve Society. He received the Annual Achievement Award of the Canadian Society of Echocardiography, the Canadian Cardiovascular Society Research Achievement Award, the Feigenbaum Lecture Award, and the CIHR-ICRH/CCS Distinguished Lecturer Award in Cardiovascular Sciences. His research program develops and validates patient-oriented approaches to improve diagnosis, prevention, and treatment of VHD.

Affiliations and expertise
Université Laval, Canada

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