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Elsevier

Books in Life sciences

  • Avian Models of Development

    • 1st Edition
    • Volume 173
    • English
    Avian Models of Development provides practical and experimental approaches for using avian systems to study developmental processes. It covers key methods, model applications, and emerging techniques that support research in embryogenesis, tissue formation, gene function, and developmental mechanisms.

  • Advanced and Sustainable Biotechnologies from Fungi

    Functional Foods and Nutraceutical Production
    • 1st Edition
    • Pragya Tiwari + 1 more
    • English
    Advanced and Sustainable Biotechnologies from Fungi: Functional Foods and Nutraceutical Production provides insights into existing and emerging fungal biotechnologies, along with advances in high-throughput technologies to enhance the sustainable production of bio-based functional foods and nutraceuticals of fungal origin. Focusing on the emerging, global concern of hunger and malnutrition, this book explains how fungi-based biotechnologies offer prospective solutions to address the global food shortage using functional foods and nutraceuticals. Chapters cover the major portion of novel sources and various biotechnological approaches used for the production of functional foods and nutraceuticals from microorganisms and mushrooms and their applications in the industry. In addition, the book includes the existing and emerging biotechnological trends and approaches in enhanced production of Functional food and Nutraceuticals of fungal origin, such as Omics-guided advances, computational strategies, and biotechnological tools. 3D printed fungal food products, and social, ethical, and regulatory aspects of functional food and nutraceutical products are also discussed. Authored by a team of experts in the field of fungi biotechnology, this book serves as a reference material for food microbiologists, food scientists, and pharmaceutical professionals for the development of new functional foods and nutraceuticals.

  • Autophagy – Part D

    • 1st Edition
    • Volume 407
    • English
    Autophagy – Part D presents current methods and advances in the study of autophagy, covering experimental approaches, molecular mechanisms, and emerging applications across different biological and disease contexts. It serves as a useful resource for researchers investigating autophagy in cell biology, physiology, and translational research.

  • Peptide-Derived Drug Discovery

    Design Strategies, Discovery Methods and Applications in Therapeutic Challenges
    • 1st Edition
    • Jian Zhang
    • English
    Peptide-Derived Drug Discovery: Design Strategies, Discovery Methods and Applications in Therapeutic Challenges provides a comprehensive exploration of peptide-like drugs, detailing their structural features and physico-chemical properties while demonstrating their application in the rational design of drug-like peptides. The book also highlights the latest advancements in peptide science, focusing on innovative technologies such as high-throughput screening methods for the macrocyclic peptide-based drug discovery. By showcasing novel approaches and offering step-by-step strategies to overcome key development challenges, this book delivers cutting-edge knowledge to advance the development of next-generation peptide therapeutics

  • Animals and Human Society

    Impacts of Animals on People and People on Animals
    • 2nd Edition
    • Colin G. Scanes + 1 more
    • English
    Animals and Human Society: Impacts of Animals on People and People on Animals, Second editon provides a solid, scientific, research-based background to advance our understanding of how animals and humans interact and impact each other. Animals and humans have had profound effects on each other throughout human history, spanning all aspects of human society from agriculture, disease, culture, religion, companionship, entertainment, environment, and more. Developed by renowned experts Colin Scanes and Clive Phillips, this second edition features a new introductory chapter covering the biological concepts necessary for technical and non-technical audiences of this book. All first edition chapters have been revised to bring readers up to date on research advancements from the last decade, and novel chapters cover animal ethics, welfare, the basis of anthrozoology, zooarchaeology, and more. Guest essays further supplement updated chapter content by providing broad interdisciplinary and geographically diverse perspectives in the field. Animals and Human Society, Second Edition is an excellent resource for academics and industry professionals requiring fundamental information on the history and biology behind human-animal interactions, as well as interested laypersons looking to augment their knowledge on the many impacts of animals in human society.

  • Fermented Foods in Health and Disease Prevention

    • 2nd Edition
    • Juana Frías + 2 more
    • English
    Fermented Foods in Health and Disease Prevention, Second Edition examines the significance of fermented foods to public health. The book presents the latest scientific evidence, showing the health-promoting components produced upon fermentation from a diversity of food matrices. The content includes the definition and characterization of traditional and innovative fermented foods, their mechanisms of action, and the evidence for effects on health and disease in humans. Putative health effects associated with direct interactions between the ingested live microorganisms and the host (probiotic effect), or indirectly, through ingestion of microbial metabolites and products of fermentation (biogenic effect) are discussed.This book will provide the food industry with new insights on the development of value-added fermentation, while also presenting nutritionists and dieticians with a useful resource to help them develop strategies to assist in the prevention of disease or to slow its onset and severity.

  • Decoding the JAK-STAT Pathway

    Emerging Insights and Clinical Applications Across Diseases
    • 1st Edition
    • Meenakshi Dhanawat + 1 more
    • English
    Decoding the JAK-STAT Pathway: Emerging Insights and Clinical Applications Across Diseases offers a comprehensive exploration of one of the most vital molecular signaling pathways in human health and immune regulation. This reference addresses the critical need for an integrated resource that connects fundamental immunological mechanisms with translational and clinical applications, particularly in autoimmune, inflammatory, and infectious diseases. The book covers the pathway’s physiological roles in cytokine signaling, immune homeostasis, and cellular communication, as well as its dysregulation in conditions such as rheumatoid arthritis, inflammatory bowel disease, neuroinflammation, and viral infections. Its chapters feature contributions from global experts, detailing recent advances in targeted therapies, including JAK inhibitors, and their potential for personalized medicine. The content is organized to highlight disease-specific roles, therapeutic strategies, and emerging research directions, making it an essential resource for immunologists, biomedical scientists, clinicians, and pharmaceutical researchers seeking an authoritative, up-to-date guide to the molecular and clinical aspects of JAK-STAT signaling. By elucidating how this pathway influences immune responses and disease progression, the book facilitates a deeper understanding of immune regulation and offers insights into novel treatment approaches, ultimately supporting advancements in immunotherapy and precision medicine across diverse patient populations worldwide.

  • Non-Invasive Brain Stimulation and Modulation of Auditory Processing

    Basic Principles and Clinical Application
    • 1st Edition
    • Jos J. Eggermont
    • English
    Non-invasive Brain Stimulation and Modulation of Auditory Processing: Basic Principles and Clinical Application provides a comprehensive overview of innovative techniques designed to address auditory processing disorders while highlighting their underlying mechanisms and clinical applications. This book addresses the distinction between hearing loss and hearing impairment, emphasizing the need for interventions that target the brain's neural processes. With a focus on both transcranial and transcutaneous stimulation methods, including transcranial magnetic stimulation (TMS) and transcutaneous electrical stimulation (TES), it explores their effects on auditory functions, cognitive processes, and long-term conditions such as tinnitus and developmental disorders. Each chapter investigates the biophysical mechanisms, therapeutic applications, and potential limitations of these non-invasive techniques, while also discussing their role in enhancing auditory attention, speech processing, and cognitive function in aging populations. By integrating neuroimaging techniques and addressing the importance of brain state, this book serves as an essential resource for researchers and clinicians seeking to understand and apply non-invasive brain stimulation methods to improve auditory processing and overall cognitive health.

  • Omics Approaches in Rhizosphere Microbiology: Part B

    • 1st Edition
    • Volume 61
    • English
    Omics Approaches in Rhizosphere Microbiology: Part A offers a definitive, systems-level exploration of the complex microenvironment where plant roots and soil microorganisms interact. As global agriculture faces the dual challenges of climate change and food insecurity, understanding the rhizosphere has shifted from traditional culture-dependent isolation to advanced high-throughput molecular auditing. This volume serves as a comprehensive, technically rigorous manual and structural roadmap, bridging foundational rhizosphere biology with the cutting-edge structural analytical tools of modern polyphasic science.

  • Pioneering Precision in Cancer Treatment through 3D Bioprinting

    • 1st Edition
    • Anand Krishnan + 3 more
    • English
    Pioneering Precision in Cancer Treatment through 3D Bioprinting explores the transformative impact of 3D bioprinting on cancer therapy. This groundbreaking book examines innovative techniques revolutionizing cancer care, from creating patient-specific tumor models to accelerating drug discovery and enabling personalized treatments. It offers a comprehensive look at how 3D bioprinting is reshaping oncology. The book details the creation of intricate tumor models that mimic the in vivo environment, enabling precise drug testing and individualized treatment plans. It highlights 3D bioprinting's role in drug screening, tumor modeling, and creating implantable scaffolds for cancer treatment.By manipulating cell arrangements and microenvironments, 3D bioprinting produces accurate cancer models. For the academic audience, this book blends bioengineering, medical insights, and real-world applications. It provides valuable case studies and developments in 3D cancer model creation, enhancing the understanding of oncogenesis, tumor progression, and therapy responses.

  • Plant Development

    • 1st Edition
    • Volume 172
    • English
    Plant Development provides an overview of the fundamental processes that govern the growth, differentiation, and organization of plants throughout their life cycle. The book explores key developmental stages, from embryogenesis and seed germination to organ formation, flowering, and senescence, highlighting the genetic, molecular, cellular, and environmental factors that regulate these events. By integrating classical concepts with modern advances in developmental biology, the volume offers valuable insight into how plants establish form, adapt to their surroundings, and coordinate growth in response to internal and external signals. It serves as a useful resource for researchers, students, and professionals interested in plant biology, developmental mechanisms, and related fields.

  • 3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology

    Innovations for Personalized Oncology
    • 1st Edition
    • Ashok Kumar + 2 more
    • English
    3D Bioprinting and Bio-Regenerative Medicine for Personalized Oncology: Innovations for Personalized Oncology presents a comprehensive exploration of the transformative role of 3-D bioprinting and bio-generative engineering in modern medicine, with a specific focus on precision oncology. By examining innovative applications of these technologies, the book aims to bridge the gap between emerging scientific advancements and their practical implications in clinical settings. It delves into how patient-specific models of human tissues and organs can revolutionize drug testing, disease diagnostics, and personalized treatment plans, ultimately enhancing the quality of cancer care.Addressing critical challenges in oncology, this book highlights how 3-D bioprinting and bio-generative engineering can improve the accuracy of drug efficacy evaluations, reduce reliance on animal testing, and tackle the pressing issue of organ shortages for transplantation. Furthermore, it emphasizes the ethical considerations and regulatory challenges associated with integrating these technologies into everyday oncology practice, ensuring a balanced perspective on their adoption.

  • RNA-Binding Proteins Part A

    • 1st Edition
    • Volume 743
    • English
    Overall, this volume serves as a comprehensive methodological resource that integrates RNA-binding proteins, RNA metabolism, phase separation, and neurodegenerative disease mechanisms. As Volume 743 of the Methods in Enzymology series, RNA-Binding Proteins highlights recent advances in the field through chapters covering topics such as RNA-Binding Proteins: Structure, Function, and RNA Interactions; RNA Granules, Phase Separation, and Biomolecular Condensates; RNA Regulation in Cellular Physiology; RNA-Binding Proteins in Neurobiology and Neurodegeneration; RNA Processing, Editing, Splicing, and Decay; Non-Coding RNAs, Small RNAs, and RNA Therapeutics; and Experimental and Computational Methods for RNA–Protein Interaction Analysis. Collectively, these contributions provide valuable methodological and conceptual insights, making the volume highly relevant to researchers in molecular biology, neuroscience, RNA biology, and translational medicine.

  • The Kidney

    • 1st Edition
    • Volume 7
    • Ahmed El-Hashash + 1 more
    • English
    The Kidney, Volume Seven in the Stem Cell Innovation in Health and Disease series, explores the emerging potential of stem cell therapies in treating kidney diseases. With their natural regenerative and anti-inflammatory properties, stem cells offer a promising approach to restoring essential kidney functions and mitigating damage. This volume highlights how stem cell therapies may modulate immune responses, promote tissue repair, and replace damaged kidney cells, offering hope for chronic and acute renal conditions. Key developments include the injection of mesenchymal stem cells (MSCs) into damaged kidneys where they can differentiate into kidney cell types and aid in healing.In addition, urine-derived stem cells have also shown significant potential in improving kidney function in preclinical studies. Additionally, innovative techniques like incorporating MSCs into compact dialysis machines are explored, enabling delivery of pro-repair factors directly to the kidneys during blood filtration. While there are currently no FDA-approved stem cell treatments for kidney diseases, ongoing clinical trials aim to evaluate their safety and efficacy. This volume compiles cutting-edge research, discussing various cell sources, underlying mechanisms, observed therapeutic outcomes, and the practical challenges of clinical translation. By presenting a clear picture of current advances and future directions, this book serves as a vital resource for scientists, clinicians, and health innovators seeking to harness stem cell technology in nephrology.

  • Melanin-Concentrating Hormone

    From Metabolism to Sleep Disorders
    • 1st Edition
    • Jackson C. Bittencourt + 1 more
    • English
    Melanin-Concentratin... Hormone: From Metabolism to Sleep Disorders, the latest volume in the Molecular Mediators in Health and Disease series, offers a comprehensive understanding of this multifunctional peptide. The book covers a wide range of topics, including molecular biology of MCH, MCH in organ function, pharmacology, and MCH in disease. Recent developments in MCH imaging and pharmacological modulation are explored, along with the impact of MCH in psychiatric and neurodegenerative disorders and its role in the neuroimmunological modulation of vitiligo. Additionally, MCH is considered in the context of reproductive behavior, sleep, cognition, memory, and peripheral function.The book also explores MCH across various species such as humans, reptiles, non-primate mammals and teleosts. This is an ideal reference for researchers working with MCH across the fields of cell biology, molecular biology, pharmacology, neuroscience, endocrinology, and beyond.

  • The Complete Book of Coronary Artery Disease

    Anatomy, Physiology, Pathology, and Management
    • 1st Edition
    • Robert "Jay" Widmer
    • English
    The Complete Book of Coronary Artery Disease: Anatomy, Physiology, Pathology, and Management covers various essential aspects related to the anatomy, embryology, anomalies, physiology, pathology, imaging, and disease management of the coronary system. The book highlights both invasive and non-invasive imaging techniques, with a focus on coronary CTA and CT-guided PCI. Intravascular imaging methods such as IVUS and OCT are elaborated on in assessing coronary health, along with a section on coronary anomalies and their incidence, diagnosis, and clinical implications. Meanwhile, information on coronary physiology explores non-pathological functions and adaptations to stressors.Coronary ischemia assessment using physiological parameters and unresolved questions regarding symptoms are also fundamental to this volume. Further, this book details coronary atherosclerosis, including pathological processes and treatment options. A non-atherosclerotic coronary anatomy section addresses pathologies impacting coronary arteries in other ways. For professionals seeking consolidated information on an oft-overlooked topic, they need look no further than this book.

  • Congenital Adrenal Hyperplasia

    A Comprehensive Guide
    • 2nd Edition
    • Peter C. Hindmarsh + 1 more
    • English
    Congenital Adrenal Hyperplasia: A Comprehensive Guide, Second Edition provides a fully-illustrated edition that outlines the basics of CAH and its interrelation with hormones and bodily function, including updated content on the latest clinical research. A new chapter dedicated to gene therapy covers principles, current status, the latest research developments, and potential treatments for congenital adrenal hyperplasia. In addition, this new release updates patient profiles due to several new clinical studies in CAH for improved condition management, with practical information on how to deal with emergencies, medic alert emergency kits, emergency injection needles, handling illness, surgery, and more.In addition, new assays are incorporated for the analysis of pituitary and adrenal hormones for the determination of the disease. This new edition continues to be a vital reference to pediatric endocrinologists as well as primary care providers to help affected patients with an updated model of care and appropriate treatment. Patients and family members will continue to benefit from the new trend-forward information presented and will be empowered to approach their health care providers with the expectation of receiving individualized care and treatment of the disorder.

  • Introduction to Tactile Intelligence

    • 1st Edition
    • Shan Luo
    • English
    Introduction to Tactile Intelligence emphasizes the growing importance of tactile intelligence, essential for robots to interact effectively with the physical world. This book explores the science of tactile intelligence, equipping robots and intelligent machines with the ability to touch and feel the world, recognize textures, develop fine motor skills, and even convey emotions through physical contact. It anticipates a future where robots seamlessly integrate with the physical world through tactile intelligence and offers solutions for its development and application in various domains. This book is a good resource for students in robotics to experienced professionals, providing a solid foundation in tactile sensing, tactile-based control, and learning, as well as the integration of tactile data into broader robotic systems. This book provides valuable insights and practical guidance, and it serves as a reference for researchers at all stages of their careers in the dynamic field of tactile development and applications.

  • Nutrigenomics for Clinical Medicine and Personalized Healthcare

    • 1st Edition
    • Dhavendra Kumar + 1 more
    • English
    Nutrigenomics for Clinical Medicine and Personalized Healthcare presents an overview of the challenges associated with bringing personalized nutrition to mainstream dietary practices in healthcare. Broken into 18 chapters, the book addresses everything from the fundamental principles of nutrigenetics and nutrigenomics to the role of nutritional factors in various diseases and disorders and the ethical practices surrounding nutritional genomics. Compiled for nutrition researchers, nutritionists, health professionals, and graduate students studying related topics, this is sure to be a welcomed reference.

  • Alcohol-Free Beer

    From Production to Consumer Perception
    • 1st Edition
    • Elisabeth Koussissi + 1 more
    • English
    Alcohol-free Beer: From Production to Consumer Perception covers this unique, emerging market segment. The book begins with introductory content and definitions before covering the production process, with a focus on fermentation methods. Nutritional aspects, flavor, and sensory characteristics of the end product as well as consumer perceptions are also covered. As the first academic book on the market to exclusively cover non-alcoholic and low ABV beer, this book will be particularly useful to researchers interested in alcoholic and non-alcoholic beverages, fermentation, and consumer behavior, especially as it relates to the consumption of alcohol (or lack thereof).Consumers seeking out better mental and physical wellbeing are opting to drink less alcohol, giving rise to this beverage trend. Yet for researchers and industry professionals crafting the product, it can be a challenge to closely replicate the pleasant taste of alcoholic beer. As the market for alcohol-free beer has undergone a unique, global rise in volume of consumption and production during the last decade, this book will be ideal for brewing chemists and beverage industry scientists hoping to create new alcohol-free beverages.

  • Correlative Light and Electron Microscopy VI

    • 1st Edition
    • Volume 213
    • English
    Correlative Light and Electron Microscopy VI presents current methods and applications in combining light microscopy and electron microscopy to study biological structures and processes with high spatial and temporal resolution. The volume highlights practical approaches for linking dynamic imaging with ultrastructural analysis, enabling researchers to investigate cells, tissues, and subcellular components in greater detail. Covering both established and emerging techniques, this book serves as a useful resource for scientists working in cell biology, structural biology, imaging, and related biomedical fields.

  • Geostatistical Approaches to Environmental and Public Health Issues

    • 1st Edition
    • Deepak Kumar + 4 more
    • English
    Geostatistical Approaches to Environmental and Public Health Issues discusses how geostatistical techniques can be leveraged to better understand and respond to pressing environmental and public health challenges. The book showcases how techniques like kriging, spatial regression, Bayesian modeling, and space-time analysis offer powerful, nuanced insights into these issues. Emphasizing stochastic, non-deterministic approaches, it highlights the importance of modeling uncertainty in both environmental and health domains. Through case studies and research-driven chapters, sections demonstrate how integrating geospatial and statistical methods can enhance our understanding of where, why, and how events occur—ultimately improving the precision of health interventions and environmental policies.By aligning cutting-edge statistical approaches with the geospatial dimensions of health and environmental data, this book fills a critical gap in the literature and supports more targeted, data-driven decision-making in the face of global uncertainty. It bridges methodological innovation with applied research, making it an essential resource for scientists, policymakers, and public health practitioners.

  • Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer

    • 1st Edition
    • Afsar Naqvi + 1 more
    • English
    Advances in Noncoding RNA Diagnostics and Therapeutics in Immunity and Cancer explores the critical role of noncoding RNAs in immune-mediated diseases and cancers, providing an essential resource on their diagnostic and therapeutic potential. The book contributes valuable insights into the pathobiology of noncoding RNAs and their application in various diseases, delving into the latest research on noncoding RNAs, including their mechanisms, interactions, and roles in disease. In addition, it examines how noncoding RNAs influence immune responses, inflammation, and cancer progression. With a focus on both diagnostic and therapeutic applications, this book highlights the potential of noncoding RNAs as biomarkers and therapeutic targets. Across comprehensive chapters, the book covers a wide range of topics, including the role of virus-encoded microRNAs in immune evasion, the therapeutic aspects of non-coding RNA in hepatocellular carcinoma, the impact of microRNAs in periodontal inflammation, and the involvement of miRNAs and lncRNAs in regulating the tumor microenvironment in HCC. Other chapters explore the functions and clinical value of tumor-derived exosomes and miRNAs in cancer immune response, the interaction of noncoding RNA in cancer metastasis, and a panorama of non‐coding RNA in prostate cancer. This book is an invaluable resource for basic science researchers in the noncoding RNA field, cancer biologists, immunologists and RNA biologists interested in the latest advancements in noncoding RNA research.

  • Peptides in Antifungal Therapy

    Cutting-Edge Innovations and Clinical Applications
    • 1st Edition
    • Awanish Kumar + 1 more
    • English
    Peptides in Antifungal Therapy: Cutting-Edge Innovations and Clinical Applications takes an interdisciplinary and comprehensive approach to antifungal peptides and the effective ways they can be utilized to combat fungal infections and improve antifungal therapies. The book begins with an introduction to antifungal peptides. It also discusses the natural and synthetic sources of antifungal peptides, details the molecular mechanisms by which these peptides fight fungal infections, and explores the clinical applications and deliver the therapeutic potential of antifungal peptides. This book will be a very useful resource for those engaged in the study of fungal infections and peptide-based therapeutics.

  • The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care

    • 1st Edition
    • Volume 192
    • English
    The Alzheimer’s Spectrum: From Neural Stress to AI-Driven Care, published as Volume 192 of the serial International Review of Neurobiology, provides a comprehensive and multidisciplinary examination of Alzheimer’s disease (AD) across its biological, psychological, and technological dimensions. This volume integrates current research on neuropsychiatric factors such as depression, stress, and anxiety with advances in neuroanatomy, systems neuroscience, and emerging AI-driven diagnostic and therapeutic approaches. Chapters explore key brain regions and circuits implicated in AD—including the thalamus, prefrontal cortex, hippocampus, and memory-emotion networks—while also addressing comorbidities, extracellular vesicles as biomarkers, and innovative treatment strategies. The inclusion of computational approaches, model organisms, and novel therapeutic avenues reflects a strong translational focus, bridging mechanistic understanding with clinical and digital health applications. Collectively, this volume serves as an authoritative resource for understanding the Alzheimer’s continuum from early cognitive impairment to advanced disease and care optimisation.

  • Shared Research Resources

    Best Practices in Management and Administration
    • 1st Edition
    • Joshua Z. Rappoport + 1 more
    • English
    Shared Research Resources: Best Practices in Management and Administration brings together best practices and case studies from research institutions around the world. Covering all areas of management, with examples and applications specific to the research environment, this is the perfect reference to build managerial skills. The first part is dedicated to introducing Shared Research Resources (SRR) management. The second part covers all aspects of staffing. Part three contains complete coverage of operations, including service development, instrument procurement, marketing, management software, customer support, safety, maintenance and repair. Part four is dedicated to fiscal management, budgeting, and reporting.Part five covers strategic management. Part six is devoted to the sustainability of the core facility. The final part covers assessment, including annual reports, program reviews, and audits. This book is a complete reference targeted at SRR managers and staff who need to keep updated with current best practices and case studies. It is also important reading for research institution managers and function leaders.

  • Plant Nutrient Strategies for Abiotic Stress Resilience

    • 1st Edition
    • Mamdouh A. Eissa
    • English
    Plant Nutrient Strategies for Abiotic Stress Resilience presents a cutting-edge exploration of how nutrient strategies can enhance crop resilience in the face of increasing abiotic stresses such as drought, salinity, heat, cold, and nutrient-poor soils. Through 18 comprehensive chapters authored by leading experts in plant nutrition and stress physiology, the book bridges fundamental scientific knowledge with practical agronomic applications. Maintaining crop productivity in the face of abiotic stressors such as drought, salinity, nutrient depletion, and climate variability continues to challenge crop producers around the world. At the same time, they need to ensure environmentally sustainable nutrient management in diverse and often fragile ecosystems. Many lack access to integrated, up-to-date knowledge that combines soil-plant nutrient dynamics with real-world strategies to combat stress in crops. From nutrient uptake mechanisms under stress conditions to advanced innovations such as nano-fertilizers and genetic approaches for nutrient efficiency, Plant Nutrient Strategies for Abiotic Stress Resilience offers an essential, science-based toolkit for researchers, students, consultants, and policymakers aiming to secure sustainable crop production in a changing climate.

  • Epigenetics and miRNA in Neurodegenerative Diseases

    From Molecular Mechanisms to Clinical Applications
    • 1st Edition
    • Lance R. McMahon + 2 more
    • English
    Epigenetics and miRNA in Neurodegenerative Diseases: From Molecular Mechanisms to Clinical Applications explores the crucial role of epigenetic modifications and microRNAs in the onset, progression, and treatment of neurodegenerative disorders such as Alzheimer’s, Parkinson’s, ALS, and Huntington’s disease. This comprehensive book bridges cutting-edge molecular research with real-world clinical applications, covering biomarker discovery, novel therapeutics, gene editing, and AI-driven bioinformatics. With clear explanations, case studies, and future perspectives, it serves as an essential resource for researchers, clinicians, and biotech professionals working toward innovative solutions for neurodegenerative disease diagnosis and treatment

  • Grain Drying, Cooling and Storage

    Theory, Technology, and Applications
    • 1st Edition
    • Werner Muhlbauer + 1 more
    • English
    Grain Drying, Cooling and Storage: Theory, Technology, and Applications is an authoritative and comprehensive handbook addressing the critical postharvest processes of grain drying, handling, storage, and cooling. With global food security increasingly challenged by climate change, energy scarcity, and geopolitical conflicts, efficient and sustainable grain preservation technologies have never been more essential.This book responds to the urgent need for updated, practical knowledge that supports reducing postharvest losses, maintaining grain quality, and optimizing energy use across diverse agricultural systems worldwide. The handbook covers both theoretical foundations and practical applications, integrating the latest research and innovations in drying kinetics, energy-efficient technologies, and quality preservation. It uniquely includes detailed models for single grain and bulk drying, novel optimization strategies, and extensive evaluations of equipment such as conveyors, cleaning machines, burners, furnaces, and various dryer types. Special attention is given to emerging renewable energy solutions and technologies suited for developing countries and smallholder farms, bridging the gap between scientific advances and real-world implementation. The inclusion of grain cooling and comprehensive storage methods further enhances its value as a complete postharvest resource.Grain Drying, Cooling and Storage: Theory, Technology, and Applications empowers engineers, researchers, and industry professionals in the food industry with practical guidelines, technical data, and quality-focused strategies to improve grain handling processes. By combining scientific rigor with hands-on insights, the book aids in maximizing drying efficiency, reducing energy consumption, preserving grain quality, and ensuring food safety. Its global perspective and extensive coverage make it an indispensable reference for anyone involved in grain production, processing, and storage, supporting sustainable agriculture and food security worldwide.

  • Big Data Analytics in Agriculture

    Algorithms and Applications
    • 1st Edition
    • Manish K. Pandey + 3 more
    • English
    Big Data Analytics in Agriculture focuses on the quantitative and qualitative assessment of agricultural systems using state‑of‑the‑art technologies to deliver practical improvements in agricultural production.Addressin... the challenge of translating data into real‑world applications, the book provides a comprehensive mapping of the entire data lifecycle—from data generation, storage, and curation to processing and implementation. It guides readers through the steps required to produce high‑quality, reliable information that supports effective decision‑making. Following a logical progression, the volume demonstrates how diverse data streams converge into decision‑support systems and how they can be transformed into actionable outcomes, aligned with intelligent, efficient, technologically advanced, economically viable, and politically and culturally sustainable practices.This book further explores the integration of information and communication technologies (ICT) and the Internet of Things (IoT) for managing rural assets and enhancing economic and environmental performance in spatially and temporally variable agricultural environments. Topics covered include big data analytics, data management and processing, and a range of algorithms and applications relevant to agriculture. Subtopics encompass artificial intelligence‑ and machine‑learning‑ena... smart and precision irrigation, disease and pest management, microclimatic forecasting, preventive fertigation and chemigation, data‑driven smart farming through the Internet of Everything (IoE), and supply‑chain analytics for improved farm‑level operations.

  • Innovation in Emergency Medicine

    Technology Development and Commercialization Handbook
    • 1st Edition
    • Nancy Patterson + 3 more
    • English
    Innovation in Emergency Medicine: Technology Development and Commercialization Handbook is a step-by-step guide to emergency medicine technology innovation reflecting recent trends of industry globalization and value-conscious healthcare. Written by a team of medical, engineering, and business experts, the authors provide a comprehensive resource that leads engineers, clinicians, students, researchers, and entrepreneurs through a clear process for the identification, invention, and implementation of new solutions. Case studies on innovative products from around the world, successes and failures, practical advice, and end-of-chapter 'Getting Started' sections encourage readers to learn from real projects and apply important lessons to their own work. This new volume in the Clinical and Medical Innovation Series will be of interest to every biomedical engineer and those working in emergency medicine who has ever had a good idea for an invention but does not know where and how to start bringing it to the bedside.

  • Electrocardiography of Laboratory Animals

    • 3rd Edition
    • Meg M. Sleeper + 1 more
    • English
    Electrocardiography of Laboratory Animals, Third Edition, provides the latest information on critical topics such as safety electrocardiography, toxicology, safety pharmacology, and telemetry, ensuring that readers are well-equipped with the knowledge required for accurate ECG interpretation in preclinical studies. The book begins with the fundamental principles of electrocardiography and its applications in drug safety evaluation but then covers electrocardiography in a wide range of laboratory animals, including rodents, guinea pigs, rabbits, cats, dogs, and various non-human primates such as marmosets, cynomolgus monkeys, rhesus monkeys, baboons, and chimpanzees.Addition... it reviews the ECG characteristics of minipigs, nanopigs, and micropigs. The text also includes chapters on telemetry and echocardiography in preclinical safety studies, as well as discussions on important parameters like PR (PQ), QRS, and QT intervals. The book concludes with chapters on cardiac assays, biomarkers, stem cells, and cardiovascular medical devices, providing a holistic view of cardiovascular research. It is an essential resource for biological and medical researchers, veterinarians, zoologists, and students.

  • Olive 4.0

    Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production
    • 1st Edition
    • Najla Trabelsi + 1 more
    • English
    Olive 4.0: Digital Transformation and Smart Technologies for Sustainable Olive Farming and Oil Production explores the revolutionary impact of Industry 4.0 technologies on the traditional olive sector. As olive farming and oil production face increasing pressures from labor shortages, resource constraints, and environmental concerns, this book addresses the urgent need for digital innovation tailored specifically to this industry. By focusing on cutting-edge tools such as the Internet of Things (IoT), Artificial Intelligence (AI), robotics, blockchain, and smart sensors, it highlights how these advances can enhance sustainability, productivity, and quality throughout the entire olive supply chain—from grove management to oil processing and distribution.Whether for smallholders seeking affordable solutions or large producers aiming for automation and traceability, the book delivers science-backed insights that promote eco-friendly practices while improving efficiency and reducing waste. Importantly, it also addresses challenges related to technology accessibility and equitable adoption, ensuring that innovations benefit a broad spectrum of stakeholders and support long-term sustainability goals.

  • Introduction to Bioinformatics and Machine Learning

    • 1st Edition
    • Milana Frenkel-Morgenstern
    • English
    Introduction to Bioinformatics and Machine Learning provides comprehensive instruction in modern computational biology by integrating bioinformatics, genomics, artificial intelligence, and machine learning into a unified learning framework. The book bridges the gap between biological data analysis and computational methods, covering fundamental concepts in molecular biology and bioinformatics together with practical applications of machine learning to genomics, transcriptomics, proteomics, microbiome research, structural biology, NGS technologies, liquid biopsy, cancer genomics, and precision medicine. Readers are introduced to DNA and RNA sequencing technologies, genome assembly, sequence alignment, variant discovery, gene expression analysis, fusion gene detection, protein structure prediction, biological databases, statistical analysis, explainable artificial intelligence, and predictive modeling. Throughout the book, real-world biomedical case studies demonstrate how computational methods are transforming modern biological and clinical research; and both bioinformatics and machine learning are addressed in a coherent and accessible manner, emphasizing practical problem-solving, reproducible computational workflows, and biological interpretation of results.Designed for upper-level undergraduate students, graduate students, and researchers, this book serves as both a classroom textbook and practical assignments for those working at the interface of biology, computer science, medicine, and data science.

  • Endophyte Technology

    An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability
    • 1st Edition
    • Zahoor Ahmed Wani + 2 more
    • English
    Endophyte Technology: An Integrative Approach for Agriculture, Healthcare, and Environmental Sustainability explores how understanding endophyte biology can be utilized in agriculture, medicine, and environmental remediation. As the global population continues to grow, the pressures on agricultural systems to produce sufficient food sustainably are intensifying. Concurrently the need for innovative medical solutions and effective environmental conservation practices is becoming increasingly urgent. This book addresses these critical needs by offering a detailed account of endophytes and their potential applications across these important fields.The book is structured into three parts, covering agricultural, ecological, and pharmaceutical aspects of endophytes. Part I looks into the role of endophytes in agriculture, discussing their potential in promoting plant growth, enhancing nutrient acquisition, and providing stress tolerance to plants. It explores how endophytes can promote sustainable agriculture, reducing the reliance on synthetic fertilizers and pesticides. Subsequent chapters explore topics such as endophyte colonization patterns, phytohormone production, and the development of bioformulations like biofertilizers, biopesticides, and biocontrol agents. Part II focuses on the ecological significance of endophytes, examining their role in ecosystem functioning, bioremediation, and adaptation to extreme environments. Part III highlights the pharmaceutical potential of endophytes, centering their ability to produce bioactive metabolites with antimicrobial, anticancer, and anti-inflammatory properties, and their role in drug discovery and biofuel production.This book is an important resource for undergraduate and postgraduate students as well as researchers and professionals in agriculture, horticulture, botany, biochemistry, and biotechnology.

  • Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies

    • 1st Edition
    • Gentle Sunder Shrestha + 3 more
    • English
    Algorithmic Approaches for the Diagnosis of Common Neurological Emergencies is a practical resource aimed at clinicians working in the field of neurology. By providing an algorithmic approach to diagnosing patients, this volume helps clinicians quickly and systematically approach patients, minimizing the risk of missing common neurological emergencies. Offering case studies and various common neurological scenarios, readers will be able to pick up on warning signs of serious neurological emergencies and treat patients effectively. Users will find this to be a valuable guide to help manage patients with neurological emergencies with limited resources.

  • Federated Intelligence in Medicine

    AI-Driven Robotics for Secure and Intelligent Healthcare Systems
    • 1st Edition
    • Manisha Guduri + 3 more
    • English
    Federated Intelligence in Medicine: AI-Driven Robotics for Secure and Intelligent Healthcare Systems explores the rapidly evolving field where medical robotics intersects with cutting-edge artificial intelligence and secure data-sharing technologies. Covering a comprehensive range of topics, the book begins with foundational knowledge in medical robotics and Generative AI, progressing to advanced concepts such as federated learning and architectural modeling tailored for AI-driven robotic systems. Readers will explore algorithms enhancing surgical robotics, remote robotic surgeries, and human-robot interaction. The text also tackles AI-driven diagnostic robots, privacy preservation through homomorphic encryption, and differential privacy and emerging medical imaging techniques integrated with robotics.Later chapters examine the synergy of large language models, agent AI, and edge AI with robotic technologies, providing both theoretical frameworks and practical case studies that illuminate real-world applications and challenges. This book is an invaluable resource for researchers and academicians engaged in artificial intelligence, robotics, and medical technology. It also serves undergraduate and graduate students in Biomedical Engineering, Electronics and Electrical Engineering, and Computer Science and Engineering.

  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.

  • Applications of Microfluidics Device Technology

    • 1st Edition
    • Volume 227
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale. This volume highlights the applications of microfluidics in the detection and analysis of infectious diseases caused by bacteria, viruses, fungi, and protozoa. It also explores the use of microfluidic technologies in the diagnosis and study of non-infectious diseases, including cardiovascular disorders, cancer, metabolic diseases, and neurological conditions. It also covered single-cell analysis, high-throughput drug screening, cell sorting, and both preclinical and clinical applications. It also used in role of microfluidics in organ culture, regenerative medicine, and personalized healthcare. It also addresses ethical and regulatory issues in the development and use of microfluidic devices. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

  • PFAS Contamination

    Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies
    • 1st Edition
    • Saranya Narayanasamy + 1 more
    • English
    PFAS Contamination: Global Prevalence, Toxicological and Ecotoxicological Impacts, and Mitigation Strategies offers a comprehensive overview of per- and polyfluoroalkyl substances (PFAS), highlighting their global environmental prevalence, toxicological effects and health risks, and state-of-the-art remediation approaches. The book taps into the increasing recognition of PFAS as “forever chemicals” and explores the widespread contamination of these compounds in water, soil, and air along with their toxicological effects on human health and the ecosystem. It highlights advancements in detection methods as well as physicochemical, biological, and emerging remediation technologies, including plasma-based technologies, bioremediation, and advanced nanotechnology-based methods, such as plasma technology, bioremediation, and adsorption methods.Case studies illustrate successful applications, and the book examines policy frameworks, regulatory measures, and the public health impact of PFAS. This resource serves as a vital source of information for environmental toxicologists, environmental scientists, environmental consultants, engineers, and regulators studying PFAS prevalence, toxicity mechanisms, remediation, and practical strategies for mitigating PFAS contamination and fostering a deeper understanding of the global efforts to address this critical issue.

  • LGBTQ+ Access to Inflammatory Bowel Disease Healthcare

    Current Trends and Considerations
    • 1st Edition
    • Lesley Dibley + 1 more
    • English
    LGBTQIA+ Access to Inflammatory Bowel Disease Healthcare: Current Trends and Considerations illuminates the unique medical, surgical, and mental health issues faced by LGBTQIA+ patients, providing clinicians with the knowledge to understand why these issues arise and how they can be effectively addressed. This crucial resource aims to elevate awareness among healthcare providers and commissioners about the need for gender- and identity-affirming care. As societal recognition of LGBTQIA+ rights grows, this book steps into the unexplored terrain of LGBTQIA+ healthcare and IBD, addressing both medical complexities and the social and political dimensions of care. The book opens with an introduction to the significance of LGBTQIA+ access to healthcare and the necessity for clinician awareness. It includes contributions from leading experts and a comprehensive glossary of relevant LGBTQIA+ terms. Key topics covered are the socio-cultural and political history influencing healthcare access, the impact of stigma on healthcare utilization and adherence, and specific medical, surgical, and mental health considerations for transgender patients with IBD. The text also covers gender- and identity-affirming practices, advocating for effective patient-provider communication and supportive healthcare environments, even in challenging settings. The concluding chapters assess the progress made and the journey ahead in LGBTQIA+ IBD care. Designed for clinicians and healthcare providers, this book serves as an indispensable reference, consolidating essential contemporary evidence into a single, accessible resource. Whether you are a gastroenterologist, surgeon, mental health professional, or healthcare researcher, this book offers the insights and tools necessary to deliver inclusive and effective care, keeping pace with the evolving healthcare advocacy and equality landscape.

  • Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science

    • 1st Edition
    • Rahul Mehra + 4 more
    • English
    Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is a critical resource for researchers, industry professionals, and academics seeking to stay at the forefront of the evolving food landscape. This comprehensive volume is organized into six sections, beginning with foundational principles in food, nutrition, and culinary science—covering chapters such as Interconnection Between Food, Nutrition, and Culinary Science and Fundamentals of Food Science and Technology. It then progresses by exploring cutting-edge innovations in culinary science, including Molecular Gastronomy and Neuro-Gastronomy, alongside practical insights into food processing advancements like AI and Robotics. The book dedicates significant focus to nutrition and health, highlighting breakthroughs in personalized nutrition, nutrigenomics, and functional foods. The final sections address sustainability, ethical practices, and future horizons, including discussions on food waste reduction, sustainable food systems, and future foods. Innovations and Practice in Advancing Culinary Nutrition and Integrating Food Science is vital for leveraging scientific and technological progress to develop healthier, safer and more sustainable food solutions. By integrating insights from culinary arts, food processing, and nutritional science, it equips professionals with the knowledge to innovate responsibly and address global issues such as food security, safety, and environmental impact. Whether exploring the role of emerging ingredients or the future of personalized diets, this book offers a detailed roadmap to shape the future of food in both academia and industry.

  • The Fundamentals of Customer-Centered Design of Food Products

    A Multisensory Strategy Integrating Emerging Techniques
    • 1st Edition
    • Luis H. Reyes + 3 more
    • English
    The Fundamentals of Customer-Centered Design of Food Products: A Multisensory Strategy for Integrating Emerging Techniques, is a comprehensive guide for students, and food industry professionals, dedicated to creating food and beverage products that truly resonate with today's consumers. This fundamental resource bridges the gap between traditional product-centric development and modern, holistic approaches that focus on the complete sensory and consumer experience. Divided into three sections, the book begins with laying the foundations for understanding customer-centered food product design and understanding the consumer in multisensory food experiences. Section two explores how each sensory modality interacts to influence consumer perception and satisfaction to create products with optimized nutrition and personalized consumer appeal. The book concludes with section three highlighting the technology and innovative tools such as smart sensors, digital tools, and sustainable processes, used to achieve consumer-centered food product design. The authors also discuss how to communicate sensory value in marketing and brand strategies and future perspectives in consumer-centered multi-sensory food design.

  • Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases

    • 1st Edition
    • Riccardo De Robertis
    • English
    Advanced Ultrasound with Imaging Correlations of Diffuse Liver Diseases addresses the critical need for detailed comparisons between advanced ultrasound (US) techniques and CT/MRI findings in the evaluation of liver diseases. While many books exist, few provide the in-depth analysis and practical guidelines necessary for accurate diagnosis and effective treatment planning. This book fills that gap, offering a multiparametric approach to the assessment of fibrotic and steatotic liver diseases. Inside, readers will find essential topics such as indications for liver US in diffuse liver diseases, advanced Ultrasound techniques for assessing liver fibrosis and steatosis, and the correlation between US, CT, and MRI findings.Key chapters cover the basics of liver ultrasound, conventional Doppler and microvascular flow imaging, ultrasound elastography, and the quantification of liver steatosis. Additionally, the book explores cutting-edge topics like artificial intelligence in liver ultrasound and the application of US in pediatric patients. Contributions from leading experts in the field ensure that each chapter provides valuable insights and practical advice. This is an indispensable resource for scientists, researchers, and clinicians alike. It offers clear guidelines on performing liver ultrasounds, understanding and interpreting results, and making informed comparisons with CT and MRI findings.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • Hypoxia-induced Tumor Heterogeneity and Immune Evasion

    Clinical Interventions
    • 1st Edition
    • Benjamin Bonavida + 1 more
    • English
    Hypoxia-induced Tumor Heterogeneity and Immune Evasion: Clinical Interventions explores how hypoxic stress within the tumor microenvironment drives cancer progression, immune escape, and resistance to therapy. This volume integrates foundational and cutting-edge insights into tumor biology, immunology, and therapeutic innovation. The book is structured into five parts, covering tumor heterogeneity, hypoxia-driven mechanisms, immune evasion, clinical diagnostics, and future directions. It brings together global experts to examine how hypoxia shapes tumor evolution, alters immune responses, and influences treatment outcomes. Topics include metabolic reprogramming, angiogenesis, immune suppression, and hypoxia-targeted therapies, with emphasis on translational relevance. This resource benefits researchers, clinicians, and advanced students by offering a comprehensive, up-to-date synthesis of a rapidly evolving field. It supports deeper understanding of tumor complexity and equips readers with knowledge to inform experimental design, clinical strategies, and therapeutic development in oncology.

  • Complications in Spinal Surgery

    A Comprehensive Guide
    • 1st Edition
    • Rafael De la Garza Ramos + 2 more
    • English
    Complications in Spinal Surgery: A Comprehensive Guide is a comprehensive reference for before and after surgery, covering common complications and rare complexities. The book is divided into major sections, including safety in spine surgery, general complications, complications by region (cervical, thoracic, lumbar, and sacral), complications related to pediatrics, and predictive analytics. Although some complications can happen irrespective of the spinal region, dividing into anatomical sections make the most sense for the reader. Designed to benefit both surgeons-in-training... and fellows—and seasoned professionals in orthopedic and neurosurgical spine practice, this book provides critical insights into the prevention, recognition, and management of complications.Unique to this book are the other implications of complications, such as how to approach patients and families, the medicolegal aspects of complications, and how to deal with these situations at a personal level. With its evidence-based approach, real-world case discussions, and expert perspectives, it equips readers with the knowledge and confidence to navigate the complexities of spine surgery and improve patient outcomes.

  • Social Determinants of Health in Surgery

    Research Methods and Clinical Review
    • 1st Edition
    • Steven A. Toms + 4 more
    • English
    Social Determinants of Health in Surgery: Research Methods and Clinical Review is a groundbreaking resource dedicated to examining the role of social determinants within surgical care. This book is designed for surgical trainees, healthcare providers, researchers, and policy administrators, offering a thorough exploration of how social factors impact surgical outcomes and practice. Featuring a detailed analysis of eleven key domains, it addresses the challenges and opportunities of integrating social determinants into surgical research and practice. The text provides essential guidance for those seeking to understand and improve patient outcomes through a broader, community-driven lens.In addition to its comprehensive coverage, the book delves into specialized topics such as big data analytics, ethical considerations, global health perspectives, pediatric surgical care, and clinical applications for research. It presents methodological guidance, including valuable tips and common pitfalls useful for readers at any stage of their surgical careers. The book also offers an in-depth review of social determinants research across ten major surgical specialties, highlighting significant trends, key studies, and current gaps in knowledge. Case studies and reflective interviews from experienced clinicians further enrich the reader’s understanding.

  • Lysosomal Pathophysiology of Parkinson’s Disease

    • 1st Edition
    • Mattia Volta + 1 more
    • English
    Lysosomal Pathophysiology of Parkinson’s Disease delves into the genetic and genomic revelations that have transformed our understanding of Parkinson’s Disease at the molecular level. The book highlights the critical role of the autophagy-lysosome pathway in the disease's pathogenic processes, drawing a comprehensive timeline of disease onset and progression. It offers a detailed examination of how disruptions in this pathway contribute to the hallmarks of Parkinson’s Disease, providing invaluable insights for researchers and clinicians alike. Subsequent chapters extend these insights by comparing Parkinson’s Disease to other neurodegenerative disorders such as Alzheimer’s Disease and Frontotemporal Dementia. By exploring protein pathology and synaptic alterations, the book underscores the broader implications of autophagy-lysosome dysfunction. Additionally, it discusses how the molecular perspectives gleaned from Parkinson’s Disease can inform our understanding of these other conditions, presenting a unified approach to studying neurodegeneration.

  • Multiple Faces of Takotsubo Syndrome

    Clinical Presentations, Mechanisms and Advanced Diagnostic Insights
    • 1st Edition
    • Luca Saba + 1 more
    • English
    Multiple Faces of Takotsubo Syndrome: Clinical Presentations, Mechanisms and Advanced Diagnostic Insights offers a thorough review of Takotsubo syndrome and the role of advanced imaging techniques in improving diagnosis, monitoring, and management of this complex cardiac condition. The book begins with an introduction to Takotsubo syndrome, covering its historical background, prevalence, and key clinical characteristics. Subsequent chapters delve into epidemiology, risk factors, and psychological aspects, including the impact of COVID-19 and other viral infections. Then, clinical manifestations, management, prevention, and treatments are thoroughly discussed, along with complications and prognosis. The basic science section explores the pathophysiological mechanisms, the heart-brain axis, and multi-organ involvement.A significant focus throughout is placed on invasive and non-invasive imaging modalities, including angiography, echocardiography, cardiac MRI, computed tomography, and nuclear imaging. Future directions highlight emerging biomarkers and imaging techniques for personalized medicine, and real-world case studies provide practical insights for clinicians. The book offers invaluable benefits to scientists, researchers, and clinicians alike.

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