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Elsevier

Books in Life sciences

  • The Sounds of the Diseased Heart

    • 1st Edition
    • Aldo A. Luisada
    • English
    The Sounds of the Diseased Heart presents the comprehensive study on auscultation and phonocardiography. It discusses the description of the sounds of the normal heart. It addresses the dynamic interpretation of cardiovascular murmurs. Some of the topics covered in the book are the abnormal first heart sound; hypertrophy or dilatation of the left ventricular wall; dilatation of the pulmonary artery; moderate pulmonary stenosis; atrial septal defect; changes in the duration of ejection; ventricular type of triple rhythm; and differential diagnosis between the pulmonary component, the opening snap, and the third sound. The general interpretation of triple and quadruple rhythms is fully covered. The dynamic correlations of cardiovascular murmurs are discussed in detail. The text describes in depth the semilunar valve stenosis. The mitral valve and tricuspid valve defects are presented completely. A chapter is devoted to the esophageal phonocardiography. The book can provide useful information to cardiologists, doctors, students, and researchers.

  • Clinical Ocular Pharmacology

    • 2nd Edition
    • Jimmy D. Bartlett
    • English
    Clinical Ocular Pharmacology, Second Edition covers the diagnostic and therapeutic clinical procedures in the administration of drugs to the eye. This book is organized into five parts encompassing 35 chapters that evaluate the basic pharmacologic principles that govern the different types of ophthalmic drugs. It addresses the pharmacologic agents useful in the diagnosis and treatment of ocular diseases. Some of the topics covered in the book are the basic science of ocular pharmacology; clinical administration of ocular drugs; drugs affecting the autonomic nervous system; types of local anesthetics; review of anti-inflammatory drugs; and examination of inhibitors of aqueous formation. Other parts deal with the development of contact lens solution in clinical practice and the pharmacologic management of strabismus. These topics are followed by discussions of the legal basis of using drugs in optometry and the systemic effects of ocular drugs. The concluding part is devoted to the diseases of the optic nerve. The book can provide useful information to doctors, optometrists, pediatricians, students, and researchers.

  • Progress in Biomass Conversion

    Volume I
    • 1st Edition
    • Kyosti V. Sarkanen + 1 more
    • English
    Progress in Biomass Conversion, Volume 1 reviews advances in the conversion of biomass sources such as wood and wood residues, agricultural materials, and municipal refuse to fuel, with emphasis on the potential of wood to reduce our dependence on fossil fuels. Topics covered range from wood fuel use in the forest products industry to the economic values of wood residues as fuel. Methanol from wood and pyrolysis of wood residues with a vertical bed reactor are also considered. Comprised of seven chapters, this volume begins with a discussion on living resources and renewing processes, focusing on carbon resources and cycles, biomass system assessment, and the renewability of biomass as well as the feedstock approach of producing chemicals from renewable resources. The use of wood fuel in the forest products industry is then examined, along with the economic importance of wood residues as fuel. Subsequent chapters deal with the pyrolysis of wood residues in a vertical bed reactor; the derivation of methanol from wood; practices for recovering energy from municipal waste in Europe and the United States; and silvicultural energy farms as a potential source of wood fuel in the long term. This book should appeal to energy policymakers as well as public utilities, manufacturing plants, and public institutions interested in biomass fuel utilization.

  • Wheat Studies - Retrospect and Prospects

    • 1st Edition
    • Volume 3
    • H. Kihara
    • English
    This authoritative work has been written by a man whose career as an active wheat geneticist has spanned sixty years and has earned him a world-wide reputation. The book contains descriptions and much original data on genetical and cytogenetical findings concerning cultivated wheats and their relatives. It covers chromosomal analyses, genome analyses, ancestors of wheat, artificial synthesis of wheat, evidence of cytoplasmic inheritance and variations of wild species. The author explains how these facts and concepts have been discovered, points out the importance inherent in these discoveries, and shows how they can be utilized in genetical and breeding studies. Special emphasis is placed on the motives, processes and development of the studies.

  • Case Presentations in Heart Disease

    • 2nd Edition
    • Alan Mackintosh
    • English
    Case Presentations in Heart Disease: Second Edition presents cases dealing with the diagnosis and treatment of patients with a heart related problem. This book addresses the need for a sample of real life cardiologic problems. Some of the topics covered in the book are the case of the 63-year-old brewery worker with severe pain between the shoulder blades; a case of a 54 years old woman with pain in her right loin; a case of a man applying for insurance; and a case of a married man who experienced loss of consciousness lasting 5 minutes. Other topics discussed include the causes of dissecting aortic aneurysm, the diagnosis made on the female with pain in her right loin, and the development of atrial myxomas. The acute phase of a myocardial infarction is presented. The concluding part is devoted to the analysis of a case of coughing symptom with no smoking history. The book can provide useful information to doctors, cardiologists, students, and researchers.

  • Andreas Vesalius Bruxellensis

    The Bloodletting Letter of 1539: An Annotated Translation and Study of the Evolution of Vesalius's Scientific Development
    • 1st Edition
    • John B. De C. M. Saunders + 1 more
    • English
    Andreas Vesalius Bruxellensis: The Bloodletting Letter of 1539 provides an insight into the knowledge of anatomy in that period. This book presents an overview of the development of the practice of venesection. This text discusses the discovery of the venous valves in the human body. Vesalius points out in this text the anatomical basis for the employment of phlebotomy. This book is liberally annotated to guide the readers. Medical historians will find this book extremely useful.

  • Electron-Microscopic Structure of Protozoa

    International Series of Monographs on Pure and Applied Biology: Zoology
    • 1st Edition
    • D. R. Pitelka
    • G. A. Kerkut
    • English
    Electron-Microscopic Structure of Protozoa mainly discusses the structure and taxa of protozoa. This text first discusses protozoa as cells, wherein the author emphasizes that these unicellular organisms be compared with a whole metazoan organism than with any of its component cells. This book then studies the protozoan superclass Rhizopoda, subphylum Actinopoda, slime molds, and subphylum Sporozoa, as well as toxoplasma. Phytoflagellates, zooflagellates, and ciliates are also tackled. This book concludes by explaining membrane differentiations, fibrous structures, and relationships of protozoa. This publication will be invaluable to biologists and other scientists interested in studying protozoa.

  • Methods in Behavioral Pharmacology

    • 1st Edition
    • Volume 10
    • F. van Haaren
    • English
    Methods in Behavioral Pharmacology is unique in offering a complete description and critical evaluation of most, if not all, methods available to study the effects of drugs on behavior. It stands apart in that it is not limited to the analysis of a particular class of pharmacological agents in a limited number of paradigms. Methods in Behavioral Pharmacology covers all paradigms without reference to specific pharmacological compounds.The book provides a comprehensive overview of the methodology used to study the behavioral effects of legal and illegal drugs. It also provides an in-depth presentation of dependent variables, their quantification and a critical evaluation of their advantages and disadvantages. An excellent work, contributed to by well-known experts in the different fields of behavioral pharmacology.

  • Toxic Interactions

    • 1st Edition
    • Robin S. Goldstein + 2 more
    • English
    Toxic Interactions is a collection of papers that discusses the basic principles behind the mechanism of toxicological interactions. This book deals with interacting chemicals and their effects on certain exposed organs or molecules. Concerning discussion of the principles, contributed papers explain the role of xenobiotic biotransformation processes in inactivating reactive intermediates of toxicants. Other authors discuss the effects of endogenous molecules and the consequences of chemically induced depletion of protective agents, as well as the pharmacokinetic principles that affect chemical interactions. Several authors also review experiments on the types of chemicals that produce or increase the degree of toxicity. The text reviews the results of liver and kidney injuries from exposure to two or more chemicals, while other papers focus on lung and heart toxicity. For example, direct mechanism of cardio toxicity includes toxicity due to an increase in plasma concentrations of the compound, or as in latent cardiac toxicity that is a product of another action on another system of organs. Professors in pharmacology, practitioners of general medicine, specialists or researchers dealing with microchemistry, toxicology or drug therapy will find this reference valuable.

  • The Clinical Aspects of Some Diseases of Cats

    • 1st Edition
    • Joan O. Joshua
    • English
    The Clinical Aspects of Some Diseases of Cats describes certain cat diseases as it occurs in the British Isles. This book is composed of 23 chapters that specifically examine conditions which occur, their relative frequency, detail symptomatology, and methods of diagnosis and treatment available in the average practice. The first chapters deal with the relationship of cat with man, its restraint, sedation, anesthesia, health, and clinical examination. Considerable chapters are devoted to numerous diseases in cat's head, eye, mouth, ear, alimentary tract, internal organs, peritoneal cavity, reproductive, nervous, and skeletal system, and skin. The remaining chapters describe diseases due to infective agents and sepsis. These chapters also discuss issues on quarantine, veterinary cat examinations, and cat shows. This book will prove useful to veterinarians, clinicians, and cat handlers and owners.

  • Neurology for Nurses

    • 1st Edition
    • J Bickerton + 1 more
    • English
    Neurology for Nurses is an attempt to make neurology as clear as possible, using the nursing model. The first portion of this book provides a diagram of the planes of the body that considers the nervous system anatomically, which is referenced throughout the book. The different orientations and planes of the body include the anterior (ventral) surface, posterior (dorsal) surface, lateral, medial, sagittal (median) section, Coronal (frontal) section, and transverse. Other than detailed descriptions of the anatomy and functions of nerves and the nervous system, this book provides diagnostic evaluation of diseases and clinical conditions, such as multiple sclerosis, cerebrovascular accidents, brain tumors, head injury, epilepsy, Parkinson's disease, and meningitis. This book includes as well discussions on neurological examinations, investigations, and observations. The topic on nursing care for unconscious patients is also provided. This text is aimed primarily at nursing students in training, but will also benefits those taking a post-basic nursing course in neurology.

  • Progress in Hodgkin's Disease

    • 1st Edition
    • G. W. Richter + 1 more
    • English
    International Review of Experimental Pathology, Volume 33: Progress in Hodgkin's Disease summarizes the progress made in the diagnosis and understanding of the pathogenesis of Hodgkin's disease. The first half of this volume deals with diagnostic aspects, whereas the second half focuses on recent developments in the understanding of the pathogenesis of Hodgkin's disease. The book opens with a chapter on the differential diagnosis between Hodgkin's disease and non-Hodgkin's lymphomas, and provides guidelines on how to deal with the grey areas between these two groups of diseases. Separate chapters follow on the criteria for a prognostically relevant histological grading of the most common subtype of Hodgkin's disease; data on the nodular lymphocyte predominance subtype of Hodgkin's disease; and the various reagents used to define the immunophenotype of Reed-Sternberg cells. Subsequent chapters deal with potential mediators of lymphocyte agglutination to Reed-Sternberg cells; immunological alterations in Hodgkin's disease; molecular genetic studies into the pathogenesis of Hodgkin's disease; and results of studies on Hodgkin cell lines. This book provides data that go beyond those covered in textbooks in pathology and hematology and should be of interest to all pathologists and clinicians dealing with the diagnosis and management of Hodgkin's disease, as well as to lymphoma researchers.

  • Pharmacology of Central Synapses

    • 1st Edition
    • V. V. Zakusov
    • English
    Pharmacology of Central Synapses deals with the pharmacology of the central nervous system and the mode of action of neurotropic drugs based on their influence on synaptic transmission. The neuronal structure of the nervous system, the structure of the synapses, and the phenomena of electrochemical transmission are discussed in this context. The main propositions of the synaptic theory of the action of neurotropic drugs, based on morphological, physiological, and biochemical findings, form the conceptual basis of this book. Comprised of eight chapters, this book examines the effect of neurotropic drugs on the synaptic transmission in reflex, projection, and association (commissural) tracts. The specific effects of various narcotics, neuroleptics, tranquillizers, analgesics, antidepressants, and stimulants on synaptic transmission in various structures of the central nervous system and at its different levels are described. This text also considers the differences in the sensitivity to such drugs of various synapses and their influence on the selectivity of drug action. This book explains the influence of neurotropic drugs on such aspects of nervous activity as impulse summation, after-discharge and functional lability, central inhibition, and the neurochemical mechanisms, particularly those involving monoaminergic, cholinergic, serotoninergic, and GABA-ergic components of synaptic transmission. The final chapter focuses on the effect of psychotropic drugs on behavior. This book will be helpful to scientists representing all the major areas of pharmacology, including clinical pharmacology and toxicology, as well as to internists, psychiatrists, neurologists, and anesthesiologists.

  • Molybdenum

    An Outline of its Chemistry and Uses
    • 1st Edition
    • Volume 19
    • E.R. Braithwaite + 1 more
    • English
    Molybdenum is an element with an extremely rich and interesting chemistry having very versatile applications in various fields of human activity. It is used extensively in metallurgical applications. Because of their anti-wear properties, molybdenum compounds find wide applications as lubricants - particularly in extreme or hostile environmental situations. Many molybdates and heteropolymolybdates are white and therefore used as pigments. In addition, they are non-toxic and act as efficient corrosion inhibitors and smoke suppressants. Hydroprocessing of petroleum is one of the largest industries employing heterogeneous catalysts. Molybdenum catalysts have shown great promise in the liquefaction of coal and this may develop into one of its most important catalytic uses. The use of molybdenum compounds in homogeneous catalysis is also significant.Three important classes of molybdenum compounds in the solid state are reviewed, viz., oxides, sulphides and halides. The role of molybdenum in inorganic catalysis and enzymes receives prominent mention because of their impact on the progress of science and technology. Further biochemical and enzymic factors are discussed in separate chapters and their reaction to agriculture and animal husbandry.A new classification of covalent compounds which abandons the traditional oxidation state concept allows a powerful approach to the organisation of the complex and rich chemistry of molybdenum. Dramatic colour diagrams of abundances of molybdenum compounds provide broad insights into the important features and trends in the chemistry of molybdenum including reactivity and mechanism.The book is intended for use mainly as a research monograph by the many workers who may encounter molybdenum chemistry or who are looking for its application and potential uses in different technological fields. However, it will also serve as an advanced text for university lecturers and postgraduate students interested in inorganic, physical and industrial chemistry, chemical technology or biochemistry and biotechnology.

  • Nervous System Theory

    An Introductory Study
    • 1st Edition
    • K. N. Leibovic
    • English
    Nervous System Theory: An Introductory Study focuses on the nervous system theory, stressing the means for understanding the nature of the biological system rather than the elaboration of mathematical theories. This book begins with a discussion on single-cell responses, followed by a discussion of sensory information processing that leads into models of perceptual processes and their possible neural bases. This text concludes with some general principles and theoretical investigations relating to units that make up a nervous system, through a sensory pathway and central structures. The peripheral stimuli that explain the operations of the brain are also described. This publication is a good reference for neurologists, medical practitioners, and researchers conducting work on the nervous system theory.

  • Specific Applications

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 16
    • 1st Edition
    • Joseph Sherma
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume XVI: Specific Applications presents analytical methodology for insecticides (ethoprop, fenoxycarb, fenvalerate) and five herbicides (chlorimuron ethyl, chlorsulfuron, glyphosate, metsulfuron methyl, sulfometuron methyl). The book discusses the determination of two important pesticide classes, anticoagulant rodenticides and fumigants, and the determination of other pyrethroid. Toxicologists and people involved in pesticide analysis will find the text invaluable.

  • Developmental Aspects of Oral Biology

    • 1st Edition
    • Harold C. Slavkin + 1 more
    • English
    Developmental Aspects of Oral Biology assembles within one volume selected contributions from highly competent investigators currently engaged in research on developmental problems in oral tissues. The primary objective of this book is to facilitate rapid and lucid communication among researcher, teacher, student, and the practitioner interested in oral tissues and oral diseases. This is best accomplished by providing critical surveys of discussions of the state of knowledge or concepts in relevant areas of biology that relate to development, development in terms of embryogenesis, prenatal growth and development, maturation, senescence, and developmental aberrations which manifest themselves as oral pathology. The book begins with a study on the nutritional aspects of embryogenesis. Separate chapters then cover the molecular biology of developing systems; immunological determinants in development; and the migration, interaction, and early differentiation of orofacial tissues. Subsequent chapters deal with topics such as the development of the primary and secondary palate and the taste buds; tissue interaction during in vitro odontogenesis; matrix development in mineralizing tissues; and macromolecular interactions in the connective tissues of the periodontium.

  • The Psychopharmacology of Hallucinogens

    • 1st Edition
    • Richard C. Stillman + 1 more
    • English
    The Psychopharmacology of Hallucinogens focuses on the properties, compositions, functions, transformations, and reactions of hallucinogens. The selection first offers information on the biosynthesis and action of hallucinogens in mammals; role of biogenic amines in the actions of monomethoxy-amphetam... and molecular mechanism of action of hallucinogens. The book then takes a look at the molecular determinants for interaction with the LSD receptor, including biological studies, molecular reactivity, and summation of the molecular polarization complexes. The text examines the progress on the development of a receptor model for hallucinogenic amphetamines; characterization of psychotomimetics; physical identification of hallucinogenic compounds; and aspects of the pharmacology of phencyclidine. The book also underscores the effects of LSD, mescaline, and DMT, including effects on humans, proposed model, and effects of monoamine manipulations. The text also presents analysis of hallucinogens by Pavlovian conditioning, behavioral measures of hallucinogenic behavior, and drug model of hallucinosis. The selection is a dependable reference for readers interested in the study of hallucinogens.

  • Receptors and Cellular Pharmacology

    Proceedings of the Sixth International Congress of Pharmacology
    • 1st Edition
    • E. Klinge
    • English
    Receptors and Cellular Pharmacology is a collection of the proceedings of the Sixth International Congress of Pharmacology held in Helsinki, Finland, on July 20-25, 1975 and organized by the Finnish Pharmacological Society. The papers explore developments relating to receptors and cellular pharmacology and address a wide range of topics such as the hydrophobic properties of the neuromuscular blocking agents and the use of toxins as tools in receptor studies. Comprised of 21 chapters, this volume begins with an introduction to histamine receptors, their pharmacological taxonomy and classification, their presence in the gastric mucosa, and their applications in medicine. The discussion then turns to pharmacological investigations on cells in culture; the acetylcholine receptor of intact and cultured chicken retina cells; actions of neurotoxins on the acetylcholine receptor; and the isolation and characterization of membrane receptors. Subsequent chapters deal with cyclic nucleotides as mediators of drug action, with particular reference to the mechanism of the relaxation-promoting effects of epinephrine on the mammalian heart. This book should be of interest to pharmacologists, internists, psychiatrists, neurologists, and anesthesiologists.

  • Mims' Pathogenesis of Infectious Disease

    • 4th Edition
    • Anthony A. Nash + 3 more
    • English
    The newly revised edition of this work provides an up-to-date description of the mechanisms of infection and disease production in a clear and logical manner. Dealing in an integrated manner with all microorganisms, the factors common to all infectious diseases are set out. Molecular biology, pathology, and immunology are brought together to explain how an infectious agent causes disease, and how the body reacts to it.

  • A Synopsis of Renal Diseases

    • 1st Edition
    • A. M. Davison
    • English
    A Synopsis of Renal Diseases presents the techniques employed for determining nephrotic syndrome. This book is composed of 15 chapters that discuss the physiology, morphology, and the blood flow to and from the kidneys. Some of the topics covered in the book are the different types of congenital deformities of the kidneys, ureters, and bladder; connections between kidneys, bladder, and the ureters; description of renal blood flow; mechanism of glomerular filtration; description of tubular function; urine concentration and dilution; mechanism of sodium and potassium excretion. Other chapters deal with the mechanism of urea excretion, the role of kidneys in the regulation of acid-base concentration, and the evaluation of the operation of renin-angiotensin system. The determination of the function of the renal is presented. The final chapters are devoted to the diagnosis and clinical features of acute glomerulonephritis and recurrent hematuria. The book can provide useful information to doctors, nephrologists, students, and researchers.

  • Prostaglandins-Immunopharmacology

    Proceedings of the 7Th International Congress of Pharmacology, Paris 1978
    • 1st Edition
    • B. B. Vargaftig
    • English
    Advances in Pharmacology and Therapeutics, Volume 4: Prostaglandins-Immun... contains the proceedings of the 7th International Congress of Pharmacology held in Paris, France, in 1978. The papers explore advances in the understanding of prostaglandins, their immunopharmacology, and their therapeutic applications. Topics covered range from the biochemistry of prostaglandins, thromboxanes, and prostacyclin to the pharmacology of blood platelets and pharmacological approaches to enhancement of immunity. This volume is comprised of 23 chapters and opens with a discussion on the discovery of prostaglandins and their possible biological functions, including platelet aggregation and adrenergic neurotransmission. The reader is then introduced to unstable metabolites of arachidonic acid in relation to thrombosis; pharmacological interference in biotransformation of arachidonic acid; participation of prostaglandins in inflammatory pain; and factors affecting the formation and actions of cyclic AMP in blood platelets. The following chapters explore the role of thymosin and the endocrine thymus in the maintenance of immune balance; effects of thymosin fraction 5 in cancer patients; and the immunoregulatory activities of non-toxic synthetic polyribonucleotides. This book will be of interest to practitioners in biosciences, pharmacology, physiology, and medicine.

  • Morphometry of the Human Lung

    • 1st Edition
    • Ewald R. Weibel
    • English
    Morphometry of the Human Lung considers the developments in understanding the quantitative anatomy of the lung, and in the correlation of anatomy with physiology. This book is composed of 11 chapters, and begins with an overview of a systematic approach to a quantitative morphologic analysis of the architecture of the human lung, followed by a presentation of general problems of methodology and the derivation of reliable dimensional models of this organ. The subsequent chapters describe the methods of preparation of tissues, methods of random sampling, and adaptation of methodologies from other fields of science. These topics are followed by discussions the mathematical formulations for the translation of the data into the desired geometric forms and a technique of counting. The final chapters look into the mode of distribution and geometric forms that should eventually facilitate mathematical and physical considerations regarding the function of the lungs. These chapters also consider the application of these quantitative methods to the study of pathologic specimens, providing a most timely renovation of morphologic pathology. This book will be of value to pulmonologists, physiologists, and researchers who are interested in lung morphometry.

  • Electrophysiological Methods

    Physical Techniques in Biological Research
    • 1st Edition
    • William L. Nastuk
    • English
    Physical Techniques in Biological Research Volume VI: Electrophysiological Methods presents the analytical methods and experimental techniques in electrophysiological research. It discusses the handling and analysis of information by computer methods. It addresses the methods of analysis of waveforms, signal characterization and detection. Some of the topics covered in the book are the fundamentals of digital and analog computers; analysis of complex waveforms; operational amplifiers; signal processing and parameter estimation; the core conductor model; voltage clamp techniques; cable theory; automatic computation equipment; and electric accounting machinery. The wave shape generation are covered. The characterization of systematic functions is discussed. The text describes the nerve containing axial wire. A study of the internal thin and outer diffuse electrodes is presented. A chapter is devoted to the simple one dimensional model. Another section focuses on the cylindrical model with radial symmetry and accuracy of membrane potential measurement. The book can provide useful information to experimenters, students, and researchers.

  • The Hallucinogens

    • 1st Edition
    • A. Hoffer + 1 more
    • English
    The Hallucinogens attempts to provide a detailed description of the hallucinogens in a single volume. Hallucinogens are chemicals which in nontoxic doses produce changes in perception, in thought, and in mood, but which seldom produce mental confusion, memory loss, or disorientation for person, place, and time. These latter changes are characteristic of organic brain reactions following intoxications with alcohol, anesthetics, and other toxic drugs. The book covers the following hallucinogens: plant ß-phenethylamines, d-lysergic acid diethylamide, ololiuqui, indole hallucinogens derived from tryptophan, and taraxein. The discussions include their chemistry, biochemistry, and neurophysiological effects. The final chapter deals with animal studies with hallucinogenic drugs. This work has been written for chemists, biochemists, psychologists, sociologists, and research physicians. While it cannot satisfy each group fully, it is sufficiently comprehensive and well documented so that each group can use it as a springboard for future enquiry into these fascinating chemicals.

  • High-Performance Liquid Chromatography of Pesticides

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 12
    • 1st Edition
    • James F. Lawrence
    • Gunter Zweig + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume XII: High-Performance Liquid Chromatography of Pesticides covers the important information on the analysis of pesticides by high-performance liquid chromatography (HPLC). The book discusses the gas chromatography of pesticides, organized according to patterns of pesticide use (procedures for insecticides, fungicides, herbicides and plant growth regulators, and rodenticides). Toxicologists and people involved in the analysis of pesticide formulations will find the text invaluable.

  • Interlimb Coordination

    Neural, Dynamical, and Cognitive Constraints
    • 1st Edition
    • Stephan P. Swinnen + 3 more
    • English
    This comprehensive edited treatise discusses the neurological, physiological, and cognitive aspects of interlimb coordination. It is unique in promoting a multidisciplinary perspective through introductory chapter contributions from experts in the neurosciences, experimental and developmental psychology, and kinesiology. Beginning with chapters defining the neural basis of interlimb coordination in animals, the book progresses toward an understanding of human locomotor control and coordination and the underlying brain structures and nerves that make such control possible. Section two focuses on the dynamics of interlimb coordination and the physics of movement. The final section presents information on how practice and experience affect coordination, including general skill acquisition, learning to walk, and the process involved in rhythmic tapping.

  • Diagnostic Reference Index of Clinical Neurology

    • 2nd Edition
    • Pasquale F. Finelli
    • English
    Diagnostic Reference Index of Clinical Neurology aims to give the busy clinician a fast, easy-to-use guide to the core neurological literature published from 1980 to 1986. This book is divided into two sections, key words and references. The keywords section consists of neuroscience terms and each main entry is followed by reference citation numbers and corresponding references. This index, unlike the usual computerized systems for literature retrieval, is structured around clinical problems and uses the approach and terminology of a practicing neurologist. The contents were sources from the full text of articles that were published in critical core of fourteen major international English-language journals in medicine and neurology. This book will be of interest to neurology students and to practicing clinical neurologists.

  • Recent Progress in Hormone Research

    Proceedings of the 1975 Laurentian Hormone Conference
    • 1st Edition
    • Roy O. Greep
    • English
    Recent Progress in Hormone Research, Volume 32 covers the proceedings of the 1975 Laurentian Hormone Conference. The book discusses genetic approaches to steroid hormone action; the cytochemical bioassay of hormones; and crystal structure of steroids. The text also describes the gonadotropin-releasi... hormone and thyrotropin-releasin... hormone; the ontogenesis of pituitary hormones and hypothalamic factors in the human fetus; and the etiologies of sexual maturation. The epidemiologic studies of diabetes in the Pima Indians; and the adrenal cortex and essential hypertension are also considered. The book further tackles the testicular control of follicle-stimulating hormone secretion; and nuclear receptors and the initiation of thyroid hormone action. The text then encompasses the receptor function and ion transport in turkey erythrocytes; the regulation of adenylate cyclase coupled beta-adrenergic receptors; and the control of cyclic AMP metabolism in parental and hybrid somatic cells. The molecular mechanisms of cyclic AMP action are also looked into. Endocrinologists, physiologists, molecular biologists, and biochemists will find the book invaluable.

  • Biological Markers in Psychiatry and Neurology

    Proceedings of a Conference Held at the Ochsner Clinic, New Orleans, on May 8-10, 1981
    • 1st Edition
    • Earl Usdin + 1 more
    • English
    Biological Markers in Psychiatry and Neurology is a collection of papers that details the advancement in the understanding of the biological markers that stems from psychiatric and neurological pathologies. The text first covers topics about various biological markers, such as neurochemical, enzymatic, membrane, receptors, endocrine, and physiological. Next, the selection examines the relationship between alcohol abuse and biological papers. The next part covers the genetic aspects of biological markers. The text also deals with use of tomography and modeling theory. The book will be of great use to students, researchers, and practitioners of neurology and psychiatry. Psychologists will also benefit from the text.

  • Neuropeptide Technology

    Gene Expression and Neuropeptide Receptors
    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 5: Neuropeptide Technology: Gene Expression and Neuropeptide Receptors discusses procedures and tools of assay useful for the identification, purification, and quantification of neuropeptides and their receptors. This volume is divided into two sections—neuropeptid... gene expression and neuropeptide receptors. In these sections, this book specifically discusses the assays for peptide products of somatostatin gene expression; molecular assays for rat thyrotropin-releasin... hormone gene; and structure, expression, and chromosomal localization of human gene. The gastrin-releasing peptide or mammalian bombesin; semiquantitative analysis of cellular somatostatin mRNA Levels; and atrial natriuretic factor receptor assays are also elaborated. This text likewise covers the receptors for opioid peptides in brain and autoradiography of somatostatin receptors in rat cerebellum. This publication is beneficial to neuroscientists and students intending to acquire knowledge of gene expression and neuropeptide receptors.

  • Toxic Phosphorus Esters

    Chemistry, Metabolism, and Biological Effects
    • 1st Edition
    • Richard D. O'Brien
    • English
    Toxic Phosphorus Esters: Chemistry, Metabolism, and Biological Effects aims to become a source book on organophosphate research and show how the understanding of the events following organophosphate poisoning of animals can be understood in terms of events at the molecular level. The manuscript first offers information on nonenzymic reactions and the reaction with cholinesterase in vitro. Discussions focus on hydrolysis, isomerization, oxidation, phosphorylation of the enzyme, and selectivity for different cholinesterases. The text then examines enzymic degradation and activation in vitro, effects in mammals, and effects on isolated whole tissues. The publication ponders on the effects in insects and plants, including results of poisoning, metabolism, resistance, antagonism and synergism, and phytotoxicity. The text also reviews selective toxicity, as well as excretion and storage, metabolism, design of new selective compounds, and nature of the target. The manuscript is a dependable reference for readers interested in the composition, reactions, and effects of toxic phosphorus esters.

  • Biotechnology and Food Quality

    Proceedings of the First International Symposium
    • 1st Edition
    • Shain-dow Kung + 2 more
    • English
    Biotechnology and Food Quality focuses on the potential of biotechnology in quantitatively and qualitatively modifying agriculture. The selection first offers information on the benefits of agricultural biotechnology on developed and developing countries, food quality education, and food quality, biotechnology, and the food company. Discussions focus on consumer concerns, demographic and social changes, scope and future role of food quality, and improvement of agricultural raw materials and processed foods. The manuscript then underscores how to make technology transfer work and the regulatory considerations of biotechnology. The text examines the characterization and modification of maize storage proteins; genetic modification of traits of interest to consumers and processors; and omega-3 fatty acid improvements in plants. Topics include genetic engineering of fatty acid biosynthesis, cellular genetics, molecular biology, application of technology to food products, and genetic engineering of lysine-containing alpha zeins. Cell wall dynamics, prospects for the use of genetic engineering in the manipulation of ethylene biosynthesis and action in higher plants, and molecular interactions of contractile proteins are also elaborated. The selection is a highly recommended source of data for biotechnologists, agriculturists, and food experts.

  • Cell Culture

    • 1st Edition
    • P. Michael Conn
    • English
    Methods in Neurosciences, Volume 3: Quantitative and Qualitative Microscopy is a collection of papers that deals with microscopic techniques in statistical measures. This volume describes microscopy using sophisticated stains and dyes to advance observation of tests and experiments. Section I describes autoradiography including micro chemical methods, high-resolution autoradiography, and single- or double-label quantitative autoradiography for use in imaging of brain activity patterns or determining cerebral physiology. Section II discusses the quantification of structures through statistical and computational methods including dynamic video imaging technology. Section III explains the use of tracers, toxins, or dyes in tracing neuronal connections. One paper addresses the use of small injections of axonally transported fluorescent tracers. Section IV explains staining technology such as using the silver impregnation method for frozen sections of human nervous tissue that are gathered from tissues preserved in formalin. Section V addresses freezing techniques and those using freeze-fracture methods in neurobiology. The text also discusses cryoprotection and other freezing methods to control ice crystals found in fixed or unfixed brain tissues. Section VI presents the combined and high-resolution methods in polarization microscopy and microscopic investigations. Cellular biologists, micro-chemists, and scientific researchers in the field of micro- and cellular biology will appreciate this book.

  • Marijuana

    Effects on Human Behavior
    • 1st Edition
    • Loren L. Miller
    • English
    Marijuana: Effects on Human Behavior attempts to synthesize much of the existing experimentation concerning the acute and chronic effects of marijuana and its derivatives on human behavior. The book opens with a chapter on the strategies for conducting research on marijuana. It also describes a clinical study at the University of British Columbia. The next chapter discusses the issues that have beclouded the question of legalization of marijuana in the United States. This is followed by separate chapters on the effects of marijuana on motor and mental performance; marijuana-memory research; a model of attention which can be used to describe the effects of marijuana use on cognition; and the effects of marijuana on neuropsychological functioning and learning. Subsequent chapters examine the behavioral actions of cannabis in man; compare the behavioral actions of cannabinoids in humans with those found in infrahumans, with special reference to acquisition and retention processes, timing behavior, state-dependent learning, and attention; and investigate the long-term effects of cannabis use.

  • Drugs in Cerebral Palsy

    Based on a Symposium Held at Dallas, 24-26 November, 1963
    • 1st Edition
    • Eric Denhoff + 2 more
    • Eric Denhoff
    • English
    Clinics in Developmental Medicine No. 16: Drugs in Cerebral Palsy: Based on a Symposium held at Dallas, 24-26 November, 1963 is a collection of papers of the 1963 Symposium on Drugs in Cerebral Palsy, arranged by the American Academy. This book is composed of nine chapters that cover the various components and treatment options involved in cerebral palsy. This text begins with a presentation of the many problems of drug evaluation, with an emphasis on the issue that human responses to a drug cannot be predicted from those of animals and that the response of one human to a drug may differ quite sharply from that of another. The next chapters deal with the historical developments and pharmacology of drugs in cerebral palsy, as well as the two aspects of drug evaluation, namely, the immediate or direct effects of the drug on patients and the double-blind test. The discussion the shifts to the pharmacological capacity of muscle relaxants and anti-convulsant drugs. The last chapter considers the possible toxic drug reactions, which are the result of individual idiosyncrasy and may occur regardless of drug dosage. This book will be of value to pharmacologists, neurologists, clinicians, and researchers who are interested in drug evaluation in cerebral palsy.

  • Genesis and Evolutionary Development of Life

    • 1st Edition
    • A. I. Oparin
    • English
    Genesis and Evolutionary Development of Life discusses the present state of thought on the origin and development of life. The book contains six chapters and begins with a brief history of attempts to solve the problem of the origin of life. This is followed by separate chapters the discuss the following events: the initial stages in the evolution of carbon compounds; formation of the "primitive soup"; origin of prebiological systems; evolution of "protobionts" and the origin of the first organisms; and the further evolution of the first organisms.

  • Advances in Drug Delivery Systems, 6

    Proceedings of the Sixth International Symposium on Recent Advances in Drug Delivery Systems, Salt Lake City, UT, U.S.A., February 21-24, 1993
    • 1st Edition
    • James M. Anderson + 2 more
    • English
    Advances in Drug Delivery Systems, 6 focuses on the progress in drug delivery systems as manifested in the fields of international pharmaceutics, polymer science, biotechnology, molecular biology, and cell biology. The selection first tackles biologically engineered microstructures and approaches to targeting bioactive compounds. Discussions focus on therapeutic efficiency of fatty acylated antiviral antibodies; effect of artificial fatty acylation on protein binding and uptake; and controlled release of proteins from lipid microcylinders. The text then elaborates on mucosal delivery of macromolecules and targeted delivery of diagnostic agents by surface-modified liposomes. The book examines the factors on in vitro micelle stability of adriamycin-block copolymer conjugates; vaginal and reproductive system treatments using a bioadhesive polymer; and control of the disposition profiles of proteins in the kidney via chemical modification. The publication also takes a look at drug delivery using biodegradable microspheres; approaches to improved antibody- and peptide-mediated targeting for imaging and therapy of cancer; and biodegradable microspheres for the delivery of oral vaccines. The selection is a valuable source material for scientists and readers interested in the advances in the systems of drug delivery.

  • Progress in Chemical Toxicology

    Volume 3
    • 1st Edition
    • Abraham Stolman
    • English
    Progress in Chemical Toxicology, Volume 3 explores the developments in methods and instrumentation for toxicological analyses. This book is composed of eight chapters, and begins with a description of the pharmacologic and physiologic effects of aliphatic alcohols. The succeeding chapter deals with the methods of analysis of various volatile poisons, such as halogenated aliphatic compounds, aromatic hydrocarbons, and acid compounds. A chapter focuses on the methods of determination and classic procedures for carbon monoxide analysis in breath and blood. These topics are followed by discussions on the development of spectrochemical methods chemical and radiochemical methods of determination of radionuclides in human bones and tissues; and the toxic effects of combined drug action. The last chapter examines the poison residue occurrence in human tissues. This book is of great value to toxicologists and public health workers and researchers.

  • Development of Responsiveness to Steroid Hormones

    Advances in the Biosciences
    • 1st Edition
    • Alvin M. Kaye + 1 more
    • English
    Development of Responsiveness to Steroid Hormones is a collection of papers presented at the Bat-Sheva Seminar of the same name which was held in Rehovot, Israel, on October 18-26, 1978 and sponsored by the Bat-Sheva de Rothschild Foundation for the Advancement of Science in Israel in cooperation with The Weizmann Institute of Science. Contributors explore how the steroid receptor complex modulates transcription of RNA and cover topics ranging from the sequential acquisition of responsiveness to estrogen in the rat uterus to the ontogeny of steroid receptors in the guinea pig. This book is comprised of 29 chapters and begins with a review of estrogen and estrogen effects in rat uterus and pituitary in culture. The embryonic chick Müllerian duct and several fetal guinea pig organs are then considered, followed by discussions on mammalian and chick liver, multi-hormonal control in rat liver; progesterone and decidualization; and rat mammary gland in culture. Glucocorticoids in developing pancreas, lung, and liver are examined, along with ecdysteroids in both locusts and Drosophila. Refractoriness is exemplified by gonadotropin action in the ovary. The remaining chapters deal with the role of steroid hormone receptors in brain development; the neural trigger for ovulation; aromatization and development of responsiveness of the brain to gonadal steroids; and neuroendocrine correlates of female-offspring interaction in maternal rats. This monograph will be of value to physiologists, biologists, and biochemists.

  • Clinical Neuroendocrinology

    • 1st Edition
    • G. M. Besser + 1 more
    • English
    Clinical Neuroendocrinology, Volume II discusses neuroendocrine science and its application to the analysis of human physiology and behavior. This book stresses the importance of the interrelationships between central and peripheral signals, neurotransmitters and neuromodulators, and target glands and peripheral tissues to ensure coordination of somatic and behavioral development and function. The ""centralist"" concepts of the importance of brain hormones are revised in this text, emphasizing that neurohumoral factors isolated from brain tissues, and initially considered to be primarily involved in the central nervous system regulation of the endocrine system, also exist outside the brain and spinal cord. This volume is valuable to neuroendocrinologist... but is also a good source for those involved in basic and clinical research and patient management.

  • Fats in Animal Nutrition

    • 1st Edition
    • J. Wiseman
    • English
    Fats in Animal Nutrition provides a useful text containing information from many diverse disciplines that discuss the nutritional utilization of lipids of domesticated animals. The book is divided into seven parts. Part I covers the chemistry and biochemistry of animal and plant fats and their nutritional importance; Part II discusses the general principles involved in the transport and absorption of fats and how this process is facilitated in ruminant and non-ruminant animals. The book also deals with the role of essential fats in the nutrition of different animals, as well as the protective functions of fat-soluble vitamins . Part IV discusses the use of fats as an energy source for animals; Part V deals with the inclusion of fats in animal feeds and their uses. The deposition of fat in different meats and the practical applications of fat utilization in animals are covered as well. The text is recommended for agriculturists, veterinarians, and zoologists who would like to know more about the importance of the inclusion of fats in animal diets.

  • Metabolic Activation and Toxicity of Chemical Agents to Lung Tissue and Cells

    • 1st Edition
    • T.E. Gram
    • English
    Research has shown that the lung is capable of metabolically activating xenobiotics into intermediates that can covalently bind to pulmonary tissue. Further, it has been shown that the lung consists of many distinct cell types with the ability to take up and sequester metabolically unchanged drugs and chemicals that are ultimately toxic in effect. This volume reflects the extent of these developments and provides a state-of-the art reference in a rapidly evolving field incorporating both drug metabolism and pulmonary toxicology research.

  • Contributions to Thermal Physiology

    Satellite Symposium of the 28th International Congress of Physiological Sciences, Pécs, Hungary, 1980
    • 1st Edition
    • Z. Szelényi + 1 more
    • English
    Advances in Physiological Sciences, Volume 32: Contributions to Thermal Physiology is a collection of papers that details the advances in the understanding of the thermal aspects of physiology. The first part of the title presents articles about central nervous control of body temperature, while the second part covers papers about fever. Next, the selection deals with brain cooling, along with thermoregulation and sleep. The fifth part covers phylogenic aspects of temperature regulation, while the sixth part tackles acclimation. Next, the selection talks about age-related difference in temperature regulation and the peripheral effector mechanisms. The text also covers the brown adipose tissue and the relevance of exercise in regulating body temperature. The book will be of great interest to students, researchers, and practitioners of medicine and biology.

  • Principles and Practice of Restorative Neurology

    Butterworths International Medical Reviews
    • 1st Edition
    • Robert R Young + 1 more
    • English
    Principles and Practice of Restorative Neurology is a collection of topics in clinical neurology where progress through research has brought concepts of patient management. The collection emphasizes research done clinically and in experimental laboratories and attempts to discuss restorative neurology in the larger context, encompassing biology, neurobiology, and rehabilitative engineering. The book discusses the concept that neurology should be more therapeutic instead of being just diagnostic because of advances in techniques and drugs. An epidemiology of disability and the evaluation of restorative neurology are explained. The text also presents the developments in the pharmacotherapy of major neurological disorders, such as Parkinson's disease, dementia, and stroke. The use of biomechanical or rehabilitation engineering to treat impaired or lost functions in a patient is compared; the feedback mechanisms and the kinds of treatment including microsurgery, nuerostimulation methods, surgery, and molecular genetics that are applied to specific disorders are discussed extensively. The book also reviews the approaches of gene correction for disorders in the central nervous system. Finally, the future needs of neurology in terms of diagnosis and treatments are dealt with as more research, techniques, and drugs are being discovered and proved useful. The collection is intended for neurologists, neurologists in training, and other physicians whose work lies with neurological disorders. The book can also prove useful for practitioners and academicians in the fields of neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • The Molecular Biology of Neurological Disease

    Butterworths International Medical Reviews
    • 1st Edition
    • Roger N. Rosenberg + 1 more
    • English
    The Molecular Biology of Neurological Disease reviews advances that have been made in understanding the molecular mechanisms of neurological disorders as well as immediate and future applications of molecular biological techniques to clinical practice. This book explores the molecular genetics of neurological disease such as muscular dystrophy, Joseph disease, and Huntington's disease, along with the mitochondrial genes implicated in such conditions. This text is comprised of 18 chapters and begins by introducing the reader to the basic principles and methods of molecular genetic techniques used in the diagnosis of neurological disease. Attention then turns to several aspects of genetic expression in the brain, including the extent to which the genome is expressed in the brain. The next chapter focuses on the visualization of polyadenylated messenger RNAs in individual cells in mammalian brain using in situ hybridization techniques, combined with immunohistochemical localization of specific proteins and neuropeptides implicated in diseases such as Alzheimer dementia. This book also discusses the molecular biology of chemical synaptic neurotransmission; proteins involved in the regulation of nervous system development; and gene expression in skeletal muscle. This text then concludes with a summary of the ""neurological gene map"" as it stands in the latter part of 1987. This book is intended for physicians who grapple with the problems of neurological disorders on a daily basis, including neurologists, neurologists in training, and those in related fields such as neurosurgery, internal medicine, psychiatry, and rehabilitation medicine.

  • Structure-Function Properties of Food Proteins

    • 1st Edition
    • Lance G. Phillips
    • Steve L Taylor
    • English
    The functional properties of food proteins affect behavior in food systems and influence the quality attributes, structure, texture, mouth-feel, and flavor of the final product. These attributes are precisely those with which food engineers and technologists are concerned when developing new products. This innovative book provides an overview of the physical properties of proteins and how dynamic changes in conformation, structural changes, and protein-protein interactions are involved in the performance of particular functional properties such as gelation, emulsification, and foaming properties. Models used include B-Lactoglobulin, soy, and meat proteins.

  • Parasitic Protozoa

    Volume 9
    • 2nd Edition
    • Julius P. Kreier
    • English
    Updated and much expanded, the Second Edition of Parasitic Protozoa is designed to be useful to physicians, veterinarians, and research scientists concerned with diseases caused by protozoa in man, and in domestic and wild animals including fish, mollusks and insects, as well as the more commonly considered vertebrate animals. Each section contains information on disease pathogens, treatment, diagnosis, and epidemiology of the diseases caused by the various protozoans. The book is not limited to these medically-oriented subjects, but treats taxonomy, morphology, and metabolism of the organisms in such a way as to be of interest to scientists and graduate students working in the field of protozoology. The entire edition, published in ten volumes, is arranged so that subjects of common interest occupy individual volumes.

  • An Agricultural Geography of Great Britain

    The Commonwealth and International Library: Geography Division
    • 1st Edition
    • D. W. Gilchrist Shirlaw
    • W. B. Fisher
    • English
    An Agricultural Geography of Great Britain is a comprehensive account of Great Britain's agricultural geography. The relationship between agriculture and geography is highlighted, with emphasis on the points of contact between them, including soils, geology, climate, and systems of farming. The farming systems of Great Britain are described, along with the agriculture of Scotland and the border country as well as the agricultural regions of England and Wales. This book is divided into four sections and begins with an overview of the factors affecting the choice of a farming system, including economic circumstances, soil, climate, topography, disease, and the personal preference and individual skills of the farmer. The next section is devoted to Great Britain's farming systems, which include hill sheep farming and hill sheep with cattle; stock rearing and fattening; dairy farming; horticulture and market gardening, often with some livestock; and pigs and poultry. The agriculture of Scotland and the border country is then considered, followed by a discussion on the agricultural regions of England and Wales. This monograph is intended primarily for agriculturists and geographers as well as students of agricultural geography.

  • The Anatomy of Aging in Man and Animals

    • 1st Edition
    • Warren Andrew
    • English
    The Anatomy of Aging in Man & Animals presents a critical review of the characteristics of invertebrates. It discusses the physical features and parts of fishes, amphibians, reptiles, and birds. It also addresses the characteristics and physiology of mammals as well as the organization of the nervous system. Some of the topics covered in the book are the descriptions and species of protozoa; description of porifera, coelenterate, and kinds of rotifer; parts and functions of mollusca; description and reproduction of annelida; types of crustacea; studies on drosophila; analysis of nutrition, temperature, and aging; and development of the nervous system of a bee. The structures of flatworms and the development of roundworms and echinodermata are discussed. An in-depth analysis of the classes of echinoidea is provided. The characteristics of thymus in an adult amphibian are also presented. A chapter is devoted to the description of changing appearance of human skin. The book can provide useful information to scientists, biologists, students, and researchers.

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