Journals in Toxicology general
Journals in Toxicology general
Providing a broad overview of toxicological principles, mechanisms, and testing methods, this portfolio supports researchers, regulators, and clinicians. It features foundational concepts, emerging trends, and case studies that underpin safe chemical and drug use.
Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology publishes original scientific research of relevance to animals or humans pertaining to the action of chemicals, drugs, or chemically-defined natural products.Regular articles address mechanistic approaches to physiological, pharmacologic, biochemical, cellular, or molecular understanding of toxicologic/patholog... lesions and to methods used to describe these responses. Safety Science articles address outstanding state-of-the-art preclinical and human translational characterization of drug and chemical safety employing cutting-edge science. Highly significant Regulatory Safety Science articles will also be considered in this category. Papers concerned with alternatives to the use of experimental animals are encouraged.Short articles report on high impact studies of broad interest to readers of TAAP that would benefit from rapid publication. These articles should contain no more than a combined total of four figures and tables. Authors should include in their cover letter the justification for consideration of their manuscript as a short article.TAAP also issues a standing call for outstanding Invited Review Articles. Potential authors should contact the Editor-In-Chief and complete an Invited Review Proposal Form before preparing or submitting their Review Article.- ISSN: 0041-008X

Toxicon
Toxicon is affiliated with The Brazilian Society of Toxinology, The International Society on Toxinology and The North American Society of Toxinology.Toxicon is dedicated to all areas related to natural toxins and publishes peer-reviewed manuscripts describing novel findings of broad interest and importance to the toxinology community.Articles that further the understanding and knowledge of toxinology are particularly welcomed, as are review articles on toxinology. Submissions on Toxinology, Pharmacology, Immunology, Biochemistry, Health, Genetics and Molecular Biology are particularly welcomed.The journal publishes articles on the following topics:original research on toxins derived from animals, plants or microorganismsnovel findings related to the chemical, pharmacological, toxicological or immunological properties of natural toxinsmolecular biological studies of toxins and related genes from poisonous and venomous organisms that advance understanding of the role or function of toxinsthe use of toxins as tools in studying biological processesthe translational application of toxins, for example as pharmacological tools, drugs or insecticidesvenom and antivenom issuesclinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtainedepidemiologi... studies on envenoming or poisoning, provided they highlight a previously unrecognized medical problem or provide insight into the prevention or medical treatment of envenoming or poisoningproperly designed prospective community-based surveysToxicon does not accept submissions on: - Retrospective surveys of hospital records, unless species identification is rigorous and the quality of hospital records high. Properly designed prospective clinical studies or community-based surveys are strongly encouraged.- Articles describing activities of venoms or extracts, for example antibacterial, anticancer or analgesic activities, without any attempt to define the mechanism of action or purify the active component.- Bibliometric studies, unless they include a critical evaluation of the field.Toxicon has an open access companion: Toxicon: X. Both journals share the same aims and scope, editorial team, and rigorous peer review. The difference between the journals is the access model under which the journals will publish your work and the indexation status.- ISSN: 0041-0101

Reproductive Toxicology
Reproductive Toxicology is affiliated with the European Teratology SocietyDrawing from a large number of disciplines, Reproductive Toxicology publishes timely, original research on the influence of chemical and physical agents on reproduction. Written by and for obstetricians, pediatricians, embryologists, teratologists, geneticists, toxicologists, andrologists, and others interested in detecting potential reproductive hazards, the journal is a forum for communication among researchers and practitioners. Articles focus on the application of in vitro, animal and clinical research to the practice of clinical medicine.All aspects of reproduction are within the scope of Reproductive Toxicology, including the formation and maturation of male and female gametes, sexual function, the events surrounding the fusion of gametes and the development of the fertilized ovum, nourishment and transport of the conceptus within the genital tract, implantation, embryogenesis, intrauterine growth, placentation and placental function, parturition, lactation and neonatal survival.Adverse reproductive effects in males will be considered as significant as adverse effects occurring in females. To provide a balanced presentation of approaches, equal emphasis will be given to clinical and animal or in vitro work.Typical end points that will be studied by contributors include:InfertilityS... dysfunctionSpontaneo... abortionMalformation... histogenesisStillbir... growth retardationPrematuri... abnormalitiesPerinat... mortality- ISSN: 0890-6238

NeuroToxicology
Affiliated with the International Neurotoxicology AssociationNeuroToxi... specializes in publishing peer-reviewed original research papers describing the effects of toxic substances on the nervous system across the lifespan as determined in humans and/or experimental models (in vivo, in vitro, in silico). The Journal welcomes papers dealing with the neurotoxic effects of occupationally and environmentally relevant exposures to agents (chemical, physical, biological, pharmacological or naturally occurring), singly or in mixtures, including complex mixtures, such as air pollution. Papers describing neurotoxic outcomes associated with natural disasters, industrial accidents, and terrorist attacks are also welcome.Experimental (animal, in vitro, in silico) papers focused on the neurotoxic effects of undefined commercial formulas (i.e., pesticide formulations) will be considered only if the authors report the chemical composition of the formulation and/or determine whether neurotoxic effects are due to the active chemical ingredient(s), carrier, or combination. For human studies, the components of formulations or other mixtures should be identified, but if not available, the source of exposure (i.e. commercial formulation, air pollution, wildfires, hurricanes, and other natural or industrial disasters) should be described as fully as possible.NeuroToxico... welcomes papers describing interventions for mitigating or reversing neurotoxic outcomes, but will accept papers reporting on neuroprotective or neurorestorative properties of formulations, botanical extracts, or other natural products only if full chemical identification and purification information of the active molecule(s) is provided. NeuroToxicology does not accept case reports.- ISSN: 0161-813X

Toxicology
Affiliated with the German Toxicology SocietyToxicology as a multidisciplinary, data-rich field has witnessed the availability of a cutting-edge technologies to investigate mechanisms underlying adverse consequences of exposures to xenobiotic chemicals, particularly as it relates to human health. Toxicology fully embraces these advancements by serving as a hub for exchange of information regarding state-of-the-art developments in the broad field of contemporary toxicology. Journal scope emphasis is on human-relevant and mechanistic research at all levels of biological organization, ranging from the molecular scale to the organismal level. The publication priority for Toxicology is on original high-quality research and review papers on any topic relevant to toxicology, in particular related to hazard identification, all that are subject to rigorous peer-review. The Toxicology target audience includes undergraduates to full professionals in academic, industrial and regulatory settings in any part of the world.Notes from the EditorsIn order to support interpretation of published findings to human health, the journal requires inclusion of specific statements within the ABSTRACT and METHODS sections of each submitted article:ABSTRACT:The experimental system (e.g., in vivo species, cell culture, etc.) including the exposure dose or concentration and duration that produces an effect, if an effect is observed, must be described in the ABSTRACT to the manuscript.MATERIALS AND METHODS:The relevance of the experimental system and exposure dose or concentration and duration in terms of potential human exposures must be described in the Materials and Methods section of the manuscript. Justification of the exposure cannot be based solely on previous publications, but rather the comparison must be to either estimated, anticipated, or measured human exposures.The authors must identify the chemicals by CAS number, their source and purity; the method of randomization for group sampling, the number of experimental sample replicates in each treatment group, and provide a proper description of the statistical analysis of data that was employed.Journal Policy:TOXICOLOGY does not publish results from exposures to uncharacterized chemical mixtures or extracts from natural products. All exposures must be fully characterized analytically. Justification for this policy is that it is near impossible for other investigators to replicate findings of a study wherein the chemical composition of the exposure is not completely characterized.TOXICO... does not publish purely descriptive safety studies or studies describing the therapeutic efficacy of cytotoxic agents without strong emphasis on end-points relating to a proposed mechanism of toxicity.- ISSN: 0300-483X

Mutation Research: Reviews in Mutation Research
The subject areas of Mutation Research - Reviews in Mutation Research (MRR) encompass the entire spectrum of the science of mutation research and its applications, with particular emphasis on the relationship between mutation and disease. Thus, this section will cover:Advances in human genome research (including evolving technologies for mutation detection and functional genomics) with applications in clinical genetics, gene therapy and health risk assessment for environmental agents of concernGenetic toxicology and environmental mutagenesis (including the factors that modulate the genetic activity of environmental agents) will continue to be prominent topics in this section.MRR supports and follows the general direction proposed by all major societies in the field part of the International Association of Environmental Mutagenesis and Genomics Societies (IAEMGS):Asociacion Latinoamericana de Mutagenesis, Carcinogenesis y Teratogenesis Ambiental (ALAMCTA)Brazilian Association of Mutagenesis and Environmental Genomics (MutaGen-Brasil)Chin... Environmental Mutagen Society (CEMS)European Environmental Mutagenesis and Genomics Society (EEMGS)Environmental Mutagenesis and Genomics Society (EMGS)Environmental Mutagen Society of India (EMS India)Iranian Environmental Mutagen Society (IrEMS)The Japanese Environmental Mutagen Society (JEMS)Korean Environmental Mutagen Society (KEMS)Molecular and Experimental Pathology Society of Australasia (MEPSA)Pan-African Environmental Mutagen Society (PAEMS)Philippines Environmental Mutagen Society (PEMS)Thai Environmental Mutagen Society (TEMS)Other Mutation Research sections: DNA Repair Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis (MR) Mutation Research - Genetic Toxicology and Environmental Mutagenesis (MRGTEM)- ISSN: 1383-5742

Chemico-Biological Interactions
A journal of molecular, cellular and biochemical toxicologyChemico-Bi... Interactions publishes research reports and review articles that examine the molecular, cellular, and/or biochemical basis of toxicologically relevant outcomes. Special emphasis is placed on toxicological mechanisms associated with interactions between chemicals and biological systems. Outcomes may include all traditional endpoints caused by synthetic or naturally occurring chemicals, both in vivo and in vitro. Endpoints of interest include, but are not limited to carcinogenesis, mutagenesis, respiratory toxicology, neurotoxicology, reproductive and developmental toxicology, and immunotoxicology.CBI discourages papers that are descriptive in nature and that do not address toxicological mechanisms (e.g., reports of toxicological effects following chemical exposure in absence of mechanistic experiments). CBI also discourages papers reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.- ISSN: 0009-2797

Toxicology Letters
Official Journal of EUROTOXAffiliated with Austrian Society of ToxicologyAn international journal for the rapid publication of novel reports on a range of aspects of toxicology, especially mechanisms of toxicity.Toxicology Letters serves as a multidisciplinary forum for research in toxicology. The prime aim is the rapid publication of research studies that are both novel and advance our understanding of a particular area. In addition to hypothesis-driven studies on mechanisms of mammalian toxicity, Toxicology Letters welcomes seminal work in the following areas:In silico toxicologyToxicokine... pharmacokinetic (PBPK) modelingSystems toxicologyPredictive toxicology3R research in toxicologyNew approach methodology (NAMs)Adverse outcome pathways (AOPs)Integrated testing strategiesSystematic and narrative reviews and mini-reviews in various areas of toxicology will be published. Clinical, occupational and safety evaluation, hazard and risk assessment, regulatory toxicology, impact on man, animal and environment studies of sufficient novelty to warrant rapid publication will be considered. Toxicology Letters also publishes editorials, commentaries and contemporary issues in toxicology.The following types of work are not within the scopes of Toxicology Letters:Ecotoxicolog... studiesCase studiesChemopreventi... studiesPharmacologic... investigationsAuthor... are advised to follow the ARRIVE guidelines (Animal Research: Reporting of In Vivo Experiments; https://arriveguidel... and the OECD guidance document on Good In Vitro Method Practices (GIVIMP; https://www.oecd.org... In vitro or in vivo investigations conducted at concentrations or doses of no relevance to human or animal exposure will not be considered. Routes of exposure other than those relevant to human or animal exposure need to be justified. Assessment of dose-response should be an integral component of any toxicological research report. Unless adequately justified, studies conducted at a single dose level may not be considered. Test materials must be chemically defined and characterized. Investigations of chemically undefined plant extracts or uncharacterized nanoparticles will not be considered.- ISSN: 0378-4274

Toxicology in Vitro
Affiliated with the American Association for Cellular and Computational Toxicology and the European Society for Toxicology in Vitro.Toxicology in Vitro publishes original research papers, reviews and workshop reports focusing on the application and use of in vitro and in silico systems for toxicological evaluations (collectively described as New Approach Methodologies (NAM)). This includes the utilisation or the development of NAMs for assessing the potential adverse effects of chemicals for human safety assessment. In vitro techniques include primary cells, tissue slices, cell lines and stem cells (adult, embryonic and induced Pluripotent cells) or subcellular preparations thereof. Our journal strongly supports the Reduction, Refinement and Replacement (3R) of animals in toxicology evaluations.This is a wide topic and thus we have certain preferences including:Developmen... of in vitro techniques and their application to research and regulatory use (i.e. 3R principle.Mechanisti... underpinning of data.Ability to translate outcome to human safety assessment.We strongly encourage :The use of normal (non-transformed) human cells (where appropriate).Reporti... the Short Tandem Repeat (STR) profile of the cells used (especially when cells have been provided as a gift or generated in house).Free access to raw (or primary) data.Appropriate model characterisation.The use (or reduction) of animal free components, including serum. [Especially when the system was already developed under such conditions, such as the HK-2 cell line].Attention to detailed methodology and appropriate statistics. [Readers need to know how you did the experiment, how many times, how many replicates etc?]Reporting the source of the compounded tested, catalogue no. and lot no. Where the chemical has been purified or synthesised a full analytical report is expected.Quantificat... of compounds in exposure medium and/or cells over time (biokinetics).We do not accept solely in vivo investigations and rarely accept animal in vivo, in vitro hybrid papers, except where the animal data was critical in the interpretation or validation of the in vitro data (and not merely confirmatory).We generally discourage investigations relating:Unidentifie... mixtures - for example in plant extracts.Solely pharmacological investigations (e.g. demonstrating your chemical kills cancer cells in vitro is not generally acceptable).Use of non-human cells when human equivalents exist and are available.The lack of adherence to established protocols, without direct explanation.Reportin... cytotoxicity alone, with no mechanistic underpinning and/or no estimation of chemical exposure.- ISSN: 0887-2333

Comparative Biochemistry and Physiology - Part C: Toxicology & Pharmacology
Comparative Biochemistry & Physiology (CBP) publishes papers in comparative, environmental and evolutionary physiology.Part C: Toxicology and Pharmacology (CBPC), focuses on toxicological mechanisms at different levels of organization, primarily chemical and drug action, biotransformation of xenobiotics, endocrine disruptors, nanoparticles, pharmaceuticals, and natural products chemistry. Most studies employ a molecular approach in combination with observations of higher levels of organization to assess the mechanism by which xenobiotics affect physiology. Analytical verification of exposure concentrations is strongly recommended for manuscripts reporting toxicological studies.All four CBP journals support and follow the editorial direction from all the major societies in the field:Australia & New Zealand Society of Comparative Physiology and Biochemistry (ANZSCPB)American Physiological Society (APS)Canadian Society of Zoologists (CSZ)Deutsche Zoologische Gesellschaft (DZG)European Society of Comparative Physiology and Biochemistry (ESCPB)Japanese Society for Comparative Physiology and Biochemistry (JSCPB)South American Society for Comparative Physiology and Biochemistry (SASCPB)Societe de Physiologie (SDP)Society for Experimental Biology (SEB)Society for Integrative & Comparative Biology (SICB)CBP journals are focused on promoting the authors and the work published in the journal:All articles are carefully evaluated directly by the Editors-in-Chief who are leading experts in their field.Availability: contact the Editor-in-Chief for any questions you may have.The Journal will provide upon request free PDFs to all authors who may not have access to their articles via their institution or library.Publication is free to authors (no color or page charges).Supporting open access: if your funding body or institution requires your article to be open access, CBP offers that option. Please see details here.Reuse figures from any CBP article via "get rights and content" hyperlink available within each article (below author names and affiliations) on ScienceDirect.Please click here for more information on more general author services.Other CBP journals Part A (CBPA): Molecular & Integrative Physiology Part B (CBPB): Biochemistry & Molecular Biology Part D (CBPD): Genomics & Proteomics- ISSN: 1532-0456
