Journals in Toxicology general
Journals in Toxicology general
- ISSN: 0887-2333
Toxicology in Vitro
Affiliated with the American Association for Cellular and Computational Toxicology and the European Society for Toxicology in Vitro.Toxicology in Vitro publishes original research papers, reviews and workshop reports focusing on the application and use of in vitro and in silico systems for toxicological evaluations (collectively described as New Approach Methodologies (NAM)). This includes the utilisation or the development of NAMs for assessing the potential adverse effects of chemicals for human safety assessment. In vitro techniques include primary cells, tissue slices, cell lines and stem cells (adult, embryonic and induced Pluripotent cells) or subcellular preparations thereof. Our journal strongly supports the Reduction, Refinement and Replacement (3R) of animals in toxicology evaluations.This is a wide topic and thus we have certain preferences including:Developmen... of in vitro techniques and their application to research and regulatory use (i.e. 3R principle.Mechanisti... underpinning of data.Ability to translate outcome to human safety assessment.We strongly encourage :The use of normal (non-transformed) human cells (where appropriate).Reporti... the Short Tandem Repeat (STR) profile of the cells used (especially when cells have been provided as a gift or generated in house).Free access to raw (or primary) data.Appropriate model characterisation.The use (or reduction) of animal free components, including serum. [Especially when the system was already developed under such conditions, such as the HK-2 cell line].Attention to detailed methodology and appropriate statistics. [Readers need to know how you did the experiment, how many times, how many replicates etc?]Reporting the source of the compounded tested, catalogue no. and lot no. Where the chemical has been purified or synthesised a full analytical report is expected.Quantificat... of compounds in exposure medium and/or cells over time (biokinetics).We do not accept solely in vivo investigations and rarely accept animal in vivo, in vitro hybrid papers, except where the animal data was critical in the interpretation or validation of the in vitro data (and not merely confirmatory).We generally discourage investigations relating:Unidentifie... mixtures - for example in plant extracts.Solely pharmacological investigations (e.g. demonstrating your chemical kills cancer cells in vitro is not generally acceptable).Use of non-human cells when human equivalents exist and are available.The lack of adherence to established protocols, without direct explanation.Reportin... cytotoxicity alone, with no mechanistic underpinning and/or no estimation of chemical exposure.
- ISSN: 0009-2797
Chemico-Biological Interactions
A journal of molecular, cellular and biochemical toxicologyChemico-Bi... Interactions publishes research reports and review articles that examine the molecular, cellular, and/or biochemical basis of toxicologically relevant outcomes. Special emphasis is placed on toxicological mechanisms associated with interactions between chemicals and biological systems. Outcomes may include all traditional endpoints caused by synthetic or naturally occurring chemicals, both in vivo and in vitro. Endpoints of interest include, but are not limited to carcinogenesis, mutagenesis, respiratory toxicology, neurotoxicology, reproductive and developmental toxicology, and immunotoxicology.CBI discourages papers that are descriptive in nature and that do not address toxicological mechanisms (e.g., reports of toxicological effects following chemical exposure in absence of mechanistic experiments). CBI also discourages papers reporting on toxicological effects from materials, such as plant extracts or herbal medicines, that have not been chemically characterized.Benefi... to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
- ISSN: 0890-6238
Reproductive Toxicology
Reproductive Toxicology is affiliated with the European Teratology SocietyDrawing from a large number of disciplines, Reproductive Toxicology publishes timely, original research on the influence of chemical and physical agents on reproduction. Written by and for obstetricians, pediatricians, embryologists, teratologists, geneticists, toxicologists, andrologists, and others interested in detecting potential reproductive hazards, the journal is a forum for communication among researchers and practitioners. Articles focus on the application of in vitro, animal and clinical research to the practice of clinical medicine.All aspects of reproduction are within the scope of Reproductive Toxicology, including the formation and maturation of male and female gametes, sexual function, the events surrounding the fusion of gametes and the development of the fertilized ovum, nourishment and transport of the conceptus within the genital tract, implantation, embryogenesis, intrauterine growth, placentation and placental function, parturition, lactation and neonatal survival.Adverse reproductive effects in males will be considered as significant as adverse effects occurring in females. To provide a balanced presentation of approaches, equal emphasis will be given to clinical and animal or in vitro work.Typical end points that will be studied by contributors include:InfertilityS... dysfunctionSpontaneo... abortionMalformation... histogenesisStillbir... growth retardationPrematuri... abnormalitiesPerinat... mortality
- ISSN: 0300-483X
Toxicology
Affiliated with the German Toxicology SocietyToxicology as a multidisciplinary, data-rich field has witnessed the availability of a cutting-edge technologies to investigate mechanisms underlying adverse consequences of exposures to xenobiotic chemicals, particularly as it relates to human health. Toxicology fully embraces these advancements by serving as a hub for exchange of information regarding state-of-the-art developments in the broad field of contemporary toxicology. Journal scope emphasis is on human-relevant and mechanistic research at all levels of biological organization, ranging from the molecular scale to the organismal level. The publication priority for Toxicology is on original high-quality research and review papers on any topic relevant to toxicology, in particular related to hazard identification, all that are subject to rigorous peer-review. The Toxicology target audience includes undergraduates to full professionals in academic, industrial and regulatory settings in any part of the world.Notes from the EditorsIn order to support interpretation of published findings to human health, the journal requires inclusion of specific statements within the ABSTRACT and METHODS sections of each submitted article:ABSTRACT:The experimental system (e.g., in vivo species, cell culture, etc.) including the exposure dose or concentration and duration that produces an effect, if an effect is observed, must be described in the ABSTRACT to the manuscript.MATERIALS AND METHODS:The relevance of the experimental system and exposure dose or concentration and duration in terms of potential human exposures must be described in the Materials and Methods section of the manuscript. Justification of the exposure cannot be based solely on previous publications, but rather the comparison must be to either estimated, anticipated, or measured human exposures.The authors must identify the chemicals by CAS number, their source and purity; the method of randomization for group sampling, the number of experimental sample replicates in each treatment group, and provide a proper description of the statistical analysis of data that was employed.Journal Policy:TOXICOLOGY does not publish results from exposures to uncharacterized chemical mixtures or extracts from natural products. All exposures must be fully characterized analytically. Justification for this policy is that it is near impossible for other investigators to replicate findings of a study wherein the chemical composition of the exposure is not completely characterized.TOXICO... does not publish purely descriptive safety studies or studies describing the therapeutic efficacy of cytotoxic agents without strong emphasis on end-points relating to a proposed mechanism of toxicity.
- ISSN: 0024-3205
Life Sciences
Life Sciences is an international journal publishing articles that emphasize the molecular, cellular, and functional basis of therapy. The journal emphasizes the understanding of mechanism that is relevant to all aspects of human disease and translation to patients. All articles are rigorously reviewed.The Journal favors publication of full-length papers where modern scientific technologies are used to explain molecular, cellular and physiological mechanisms. Articles that merely report observations are rarely accepted. Recommendations from the Declaration of Helsinki or NIH guidelines for care and use of laboratory animals must be adhered to. Articles should be written at a level accessible to readers who are non-specialists in the topic of the article themselves, but who are interested in the research. The Journal welcomes reviews on topics of wide interest to investigators in the life sciences. We particularly encourage submission of brief, focused reviews containing high-quality artwork and require the use of mechanistic summary diagrams.Manuscripts should present novel preclinical findings addressing questions of biological significance to human disease. Studies that fail to do so may be rejected without review. Quantitative conclusions must be based on truly quantitative methods. Life Sciences does not publish work on the actions of biological extracts of unknown chemical composition. Compounds studied must be of known chemical structure and concentration. The study must be reproducible; materials used must be available to other researchers so they can repeat the experiment. Clinical studies may be considered if they expand understanding of mechanism, but the journal does not encourage clinical trial reports.Four common reasons for rejection include: out of scope (the manuscript does not conform to the goal of identification of mechanisms related to therapy for human disease); too preliminary (manuscript is based on a limited amount of experimental data diminishing significance); lack of novelty (manuscript is well done but does not address a significant question); unidentified structure (actions of biological extracts of unknown chemical composition).
- ISSN: 1382-6689
Environmental Toxicology and Pharmacology
Environmental Toxicology and Pharmacology publishes the results of studies concerning toxic and pharmacological effects of (human and veterinary) drugs and of environmental contaminants in animals and man.Areas of special interest are: molecular mechanisms of toxicity, biotransformation and toxicokinetics (including toxicokinetic modelling), molecular, biochemical and physiological mechanisms explaining differences in sensitivity between species and individuals, the characterisation of pathophysiological models and mechanisms involved in the development of effects and the identification of biological markers that can be used to study exposure and effects in man and animals.In addition to full length papers, short communications, full-length reviews and mini-reviews, Environmental Toxicology and Pharmacology will publish in depth assessments of special problem areas. The latter publications may exceed the length of a full length paper three to fourfold. A basic requirement is that the assessments are made under the auspices of international groups of leading experts in the fields concerned. The information examined may either consist of data that were already published, or of new data that were obtained within the framework of collaborative research programmes. Provision is also made for the acceptance of minireviews on (classes of) compounds, toxicities or mechanisms, debating recent advances in rapidly developing fields that fall within the scope of the journal.Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
- ISSN: 2468-2020
Current Opinion in Toxicology
Affiliated with the International Union of ToxicologyCurrent Opinion in Toxicology aims to stimulate scientifically grounded, interdisciplinary, multi-scale debate and exchange of ideas. It contains polished, concise, and timely reviews and opinions, with particular emphasis on those articles published in the past two years. In addition to describing recent trends, the authors are encouraged to give their subjective opinion of the topics discussed.In Current Opinion in Toxicology we help the reader by providing in a systematic manner: 1. The views of experts on current advances in their field in a clear and readable form. 2. Evaluations of the most interesting papers, annotated by experts, from the great wealth of original publications.Current Opinion in Toxicology serves as an invaluable source of information for researchers, lecturers, teachers, professionals, policy makers and students.Current Opinion in Toxicology builds on Elsevier's reputation for excellence in scientific publishing and long-standing commitment to communicating reproducible biomedical research targeted at improving human health. It is a companion to the new Gold Open Access journal Current Research in Toxicology and is part of the Current Opinion and Research(CO+RE) suite of journals. All CO+RE journals leverage the Current Opinion legacy-of editorial excellence, high-impact, and global reach-to ensure they are a widely read resource that is integral to scientists' workflow.Division of the subject into sections: For this purpose, the scope of Toxicology is divided into six selected, high impact themed sections, each of which is reviewed once a year:Mechanistic ToxicologyMetabolic ToxicologyRisk assessment in ToxicologyGenomic ToxicologySystems ToxicologyTranslatio... ToxicologyExpertise: Expert authors, who are leaders in their field, are invited to write short review articles in which they present recent developments in their subject and provide short annotations to the papers that they think are most relevant. Comprehensiveness: There are 27 high-impact Current Opinion review journals in a range of subjects from food science to green and sustainable chemistry. Impact: In addition to a vast readership, Current Opinion titles enjoy high citations, Impact Factors, and CiteScores. Discoverability: Articles get high visibility and maximum exposure on an industry-leading platform that reaches a vast, global audience.Selection of topics to be reviewed Editors, who are major authorities in the field, are approved by the Editors-in-Chief of the journal. They divide their sections into a number of topics, ensuring that the field is comprehensively covered and that all issues of current importance are emphasised. Editors commission reviews from authors on each topic that they have selected and arrange for the peer review process. The papers are reviewed by 2 independent reviewers.Submission... Opinion in Toxicology allows two ways to submit to the journal:Invitation – in accordance with the established procedure for all Current Opinion titles, andNEW – authors are given a “spontaneous submission option” via the pre-submission route, in order to fully open the journal to the authorship.Short Reviews Authors write short review articles (approx. 2500 words), in which they present recent developments in their subject, emphasising the aspects that, in their opinion, are most important. In addition, they provide short annotations to the papers that they consider to be most interesting from all those published in their topic over the 5 years.Editorial Overview For invitation only sections, Section Editors write a short overview at the beginning of the section, to introduce the reviews and to draw the reader's attention to any particularly interesting developments.Ethics in Publishing: General Statement The Editors and the Publisher of this journal believe that there are fundamental principles underlying scholarly and professional publishing. While this may not amount to a formal 'code of conduct', these fundamental principles with respect to the authors' paper, are that the paper should: i) be the authors' own original work, which has not been previously published elsewhere, ii) reflect the authors' own research and analysis and do so in a truthful and complete manner, iii) properly credit the meaningful contributions of co-authors and co-researchers, iv) not be submitted to more than one journal for consideration, and v) be appropriately placed in the context of prior and existing research. Of equal importance are ethical guidelines dealing with research methods and research funding, including issues dealing with informed consent, research subject privacy rights, conflicts of interest, and sources of funding. While it may not be possible to draft a 'code' that applies adequately to all instances and circumstances, we believe it useful to outline our expectations of authors and procedures that the journal will employ in the event of questions concerning author conduct. With respect to conflicts of interest, the Publisher now requires authors to declare any conflicts of interest that relate to papers accepted for publication in this journal. A conflict of interest may exist when an author or the author's institution has a financial or other relationship with other people or organizations that may inappropriately influence the author's work. A conflict can be actual or potential and full disclosure to the journal is the safest course. All submissions to the journal must include disclosure of all relationships that could be viewed as presenting a potential conflict of interest. The journal may use such information as a basis for editorial decisions and may publish such disclosures, if they are believed to be important to readers in judging the manuscript. A decision may be made by the journal not to publish on the basis of the declared conflict.For more information, please refer to: https://www.elsevier...
- ISSN: 0041-0101
Toxicon
Toxicon is affiliated with The Brazilian Society of Toxinology, The International Society on Toxinology and The North American Society of Toxinology.Toxicon is dedicated to all areas related to natural toxins and publishes peer-reviewed manuscripts describing novel findings of broad interest and importance to the toxinology community.Articles that further the understanding and knowledge of toxinology are particularly welcomed, as are review articles on toxinology. Submissions on Toxinology, Pharmacology, Immunology, Biochemistry, Health, Genetics and Molecular Biology (General) are particularly welcomed.The journal publishes articles on the following topics:original research on toxins derived from animals, plants or microorganismsnovel findings related to the chemical, pharmacological, toxicological or immunological properties of natural toxinsmolecular biological studies of toxins and related genes from poisonous and venomous organisms that advance understanding of the role or function of toxinsthe use of toxins as tools in studying biological processesthe translational application of toxins, for example as pharmacological tools, drugs or insecticidesvenom and antivenom issuesclinical observations on poisoning and envenoming where a new therapeutic principle has been proposed or a decidedly superior clinical result has been obtainedepidemiologi... studies on envenoming or poisoning, provided they highlight a previously unrecognized medical problem or provide insight into the prevention or medical treatment of envenoming or poisoningproperly designed prospective community-based surveysToxicon does not accept submissions on: - Retrospective surveys of hospital records, unless species identification is rigorous and the quality of hospital records high. Properly designed prospective clinical studies or community-based surveys are strongly encouraged.- Articles describing activities of venoms or extracts, for example antibacterial, anticancer or analgesic activities, without any attempt to define the mechanism of action or purify the active component.- Bibliometric studies, unless they include a critical evaluation of the field.
- ISSN: 0041-008X
Toxicology and Applied Pharmacology
Toxicology and Applied Pharmacology publishes original scientific research of relevance to animals or humans pertaining to the action of chemicals, drugs, or chemically-defined natural products.Regular articles address mechanistic approaches to physiological, pharmacologic, biochemical, cellular, or molecular understanding of toxicologic/patholog... lesions and to methods used to describe these responses. Safety Science articles address outstanding state-of-the-art preclinical and human translational characterization of drug and chemical safety employing cutting-edge science. Highly significant Regulatory Safety Science articles will also be considered in this category. Papers concerned with alternatives to the use of experimental animals are encouraged.Short articles report on high impact studies of broad interest to readers of TAAP that would benefit from rapid publication. These articles should contain no more than a combined total of four figures and tables. Authors should include in their cover letter the justification for consideration of their manuscript as a short article.TAAP also issues a standing call for outstanding Invited Review Articles. Potential authors should contact the Editor-In-Chief and complete an Invited Review Proposal Form before preparing or submitting their Review Article.Benefits to authors We also provide many author benefits, such as free PDFs, a liberal copyright policy, special discounts on Elsevier publications and much more. Please click here for more information on our author services .Please see our Guide for Authors for information on article submission. If you require any further information or help, please visit our Support Center
- ISSN: 0278-6915
Food and Chemical Toxicology
Affiliated with the Chinese Society of ToxicologyFood and Chemical Toxicology (FCT) is an internationally renowned journal that publishes original research articles and reviews on toxic effects and toxic mechanisms of natural or synthetic chemicals occurring in the human environment (present in food and/or the human environment). The scope of the journal includes drugs, consumer chemicals/products (e.g. cosmetics); agricultural chemicals/products (e.g. pesticides) and industrial chemicals (e.g relevant to occupational exposure). Areas such as safety evaluation of novel foods and ingredients, biotechnologically-d... products and nanomaterials are included in the scope of the journal. In these cases, a comprehensive characterisation of the materials under evaluation is necessary. FCT also encourages submission of papers on inter-relationships between nutrition and toxicology and on in vitro techniques, particularly those fostering the 3 Rs.In addition, the journal also publishes Special Issues focussed on selected subject areas. These issues typically involve new areas of interest or concern and there will be some flexibility in the papers considered in terms of scope.The principal aim of the journal is to publish high impact, scholarly work and to serve as a multidisciplinary forum for research in Toxicology. Papers submitted will be judged on the basis of scientific originality and contribution to the field, quality and subject matter.Contributors who do not heed the requirements outlined in the instructions to authors and Editorials risk manuscript rejection without further consideration.Studie... should address at least one of the following:Adverse physiological/bioche... or pathological changes induced by specific defined substances,New techniques for assessing potential toxicity,Mechanisms underlying toxic phenomena,Toxicologi... examinations of specific chemicals or consumer products, both those showing adverse effects and those demonstrating safety, that meet current standards of scientific acceptability.Author... must clearly and briefly identify what novel toxic effect (s) or toxic mechanism (s) of the chemical are being reported and what their significance is in the abstract.Studies that consider time- and dose-response effects are likely to be considered more reliable and therefore considered more favourably.Manuscrip... describing research involving the following areas will not be considered:materials... of only local interest,materials/s... for which the chemical composition is not clearly defined,only pharmacological properties or potentially beneficial effects, chemical analyses of toxins in foods without addressing the toxic implication to humans [i.e. a risk assessment should be included],unrealisti... human doses, inappropriate route(s) of exposure, or in vitro experiments that do not reflect serum levels in humans without a compelling justification.FCT is committed to the highest standards. Only papers that have not been previously published, that fit in the above-mentioned scope, and which have been reviewed by experts in the field prior to publication will be considered for eventual publication. Cover letters must be included and state that the manuscript is new and original and not under consideration for publication elsewhere. Co-authors should be individuals who have contributed substantially to the content of the papers. All authors must declare any potential conflict of interest and all financial support.Any papers offered re-submission after review must contain a separate letter containing a response to all the points raised by the Editors and reviewers.