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Books in Physical sciences and engineering

  • Hybrid Retrosynthesis

    Organic Synthesis using Reaxys and SciFinder
    • 1st Edition
    • Michael B. Smith + 1 more
    • English
    Designed to supplement existing organic textbooks, Hybrid Retrosynthesis presents a relatively simple approach to solving synthesis problems, using a small library of basic reactions along with the computer searching capabilities of Reaxys and SciFinder. This clear, concise guide reviews the essential skills needed for organic synthesis and retrosynthesis, expanding reader knowledge of the foundational principles of these techniques, whilst supporting their use via practical methodologies. Perfect for both graduate and post-graduate students, Hybrid Retrosynthesis provides new applied skills and tools to help during their organic synthesis courses and future careers, whilst simultaneously acting as useful resource for those setting tutorial and group problems, and as a helpful go-to guide for organic chemists involved in either industry or academia.

  • Prodrug Design

    Perspectives, Approaches and Applications in Medicinal Chemistry
    • 1st Edition
    • Vivekkumar K Redasani + 1 more
    • English
    Prodrug Design: Perspectives, Approaches and Applications in Medicinal Chemistry provides a focused overview of this critical area of drug discovery, as that continuous process strives not only to discover new drug compounds but also to modify the existing ones. This valuable primer supports this mission of drug development and its goal of reducing undesired effects and improving therapeutic effectiveness of drug compounds. Providing a unique compilation of data, insightful case studies, and review of existing literature in the area, the book will promote innovation in medicinal and pharmaceutical chemistry research, exploring the limitations of existing drugs and their improvement. Prodrug Design reviews marketed compounds, the safety of promoieties, and a detailed classification of prodrugs organized by therapeutic area for easy reference.

  • Big Data Analytics

    • 1st Edition
    • Volume 33
    • English
    While the term Big Data is open to varying interpretation, it is quite clear that the Volume, Velocity, and Variety (3Vs) of data have impacted every aspect of computational science and its applications. The volume of data is increasing at a phenomenal rate and a majority of it is unstructured. With big data, the volume is so large that processing it using traditional database and software techniques is difficult, if not impossible. The drivers are the ubiquitous sensors, devices, social networks and the all-pervasive web. Scientists are increasingly looking to derive insights from the massive quantity of data to create new knowledge. In common usage, Big Data has come to refer simply to the use of predictive analytics or other certain advanced methods to extract value from data, without any required magnitude thereon. Challenges include analysis, capture, curation, search, sharing, storage, transfer, visualization, and information privacy. While there are challenges, there are huge opportunities emerging in the fields of Machine Learning, Data Mining, Statistics, Human-Computer Interfaces and Distributed Systems to address ways to analyze and reason with this data. The edited volume focuses on the challenges and opportunities posed by "Big Data" in a variety of domains and how statistical techniques and innovative algorithms can help glean insights and accelerate discovery. Big data has the potential to help companies improve operations and make faster, more intelligent decisions.

  • Cloud Storage Security

    A Practical Guide
    • 1st Edition
    • Aaron Wheeler + 1 more
    • English
    Cloud Storage Security: A Practical Guide introduces and discusses the risks associated with cloud-based data storage from a security and privacy perspective. Gain an in-depth understanding of the risks and benefits of cloud storage illustrated using a Use-Case methodology. The authors also provide a checklist that enables the user, as well as the enterprise practitioner to evaluate what security and privacy issues need to be considered when using the cloud to store personal and sensitive information.

  • Modeling and Simulation of Reactive Flows

    • 1st Edition
    • A.L. De Bortoli + 2 more
    • English
    Modelling and Simulation of Reactive Flows presents information on modeling and how to numerically solve reactive flows. The book offers a distinctive approach that combines diffusion flames and geochemical flow problems, providing users with a comprehensive resource that bridges the gap for scientists, engineers, and the industry. Specifically, the book looks at the basic concepts related to reaction rates, chemical kinetics, and the development of reduced kinetic mechanisms. It considers the most common methods used in practical situations, along with equations for reactive flows, and various techniques—including flamelet, ILDM, and Redim—for jet flames and plumes, with solutions for both. In addition, the book includes techniques to accelerate the convergence of numerical simulation, and a discussion on the analysis of uncertainties with numerical results, making this a useful reference for anyone who is interested in both combustion in free flow and in porous media.

  • Developments in Turbomachinery Flow

    Forward Curved Centrifugal Fans
    • 1st Edition
    • Nader Montazerin + 2 more
    • English
    Developments in Turbomachinery Flow: Forward Curved Centrifugal Fans explores the forward curved squirrel cage fan as an excellent instrument for fluid mechanics research in turbomachines. The book explores phenomena such as jet/wake interaction, circulation, separation and noise in turbomachines, also addressing the characteristics that are specific to this fan and applications in other centrifugal turbomachines. Chapters begin with a general introduction that includes research techniques and a survey of older research, and then proceed into a detailed description of improvements for different parts of the fan, including the inlet, the rotor and the volute. Final sections include a comprehensive discussion on geometrical modifications that could improve performance without impacting cost.

  • Fillers and Reinforcements for Advanced Nanocomposites

    • 1st Edition
    • Yu Dong + 2 more
    • English
    Fillers and Reinforcements for Advanced Nanocomposites reviews cutting-edge, state-of-the-art research on the effective use of nanoscaled fillers and reinforcements to enhance the performance of advanced nanocomposites, both in industrial and manufacturing applications. It covers a broad range of topics such as nanocelluloses, nanotubes, nanoplatelets, and nanoparticles, as well as their extensive applications. The chapters provide detailed information on how fillers and reinforcements are used in the fabrication, synthesis and characterization of advanced nanocomposites to achieve extraordinary performance of new materials and significant enhancements in their mechanical, thermal, structural and multi-functional properties. It also highlights new technologies for the fabrication of advanced nanocomposites using innovative electrospinning techniques.

  • Repetitive Project Scheduling: Theory and Methods

    • 1st Edition
    • Li-hui Zhang
    • English
    Repetitive Project Scheduling: Theory and Methods is the first book to comprehensively, and systematically, review new methods for scheduling repetitive projects that have been developed in response to the weaknesses of the most popular method for project scheduling, the Critical Path Method (CPM). As projects with significant levels of repetitive scheduling are common in construction and engineering, especially construction of buildings with multiple stories, highways, tunnels, pipelines, power distribution networks, and so on, the book fills a much needed gap, introducing the main repetitive project scheduling methods, both comprehensively and systematically. Users will find valuable information on core methodologies, including how to identify the controlling path and controlling segment, how to convert RSM to a network model, and examples based on practical scheduling problems.

  • The Practice of Medicinal Chemistry

    • 4th Edition
    • Camille Georges Wermuth + 3 more
    • English
    The Practice of Medicinal Chemistry, Fourth Edition provides a practical and comprehensive overview of the daily issues facing pharmaceutical researchers and chemists. In addition to its thorough treatment of basic medicinal chemistry principles, this updated edition has been revised to provide new and expanded coverage of the latest technologies and approaches in drug discovery.With topics like high content screening, scoring, docking, binding free energy calculations, polypharmacology, QSAR, chemical collections and databases, and much more, this book is the go-to reference for all academic and pharmaceutical researchers who need a complete understanding of medicinal chemistry and its application to drug discovery and development.

  • Electromagnetic Sounding of the Earth's Interior

    • 2nd Edition
    • Volume 40
    • Viacheslav V. Spichak
    • English
    Electromagnetic Sounding of the Earth's Interior 2nd edition provides a comprehensive up-to-date collection of contributions, covering methodological, computational and practical aspects of Electromagnetic sounding of the Earth by different techniques at global, regional and local scales. Moreover, it contains new developments such as the concept of self-consistent tasks of geophysics and , 3-D interpretation of the TEM sounding which, so far, have not all been covered by one book. Electromagnetic Sounding of the Earth's Interior 2nd edition consists of three parts: I- EM sounding methods, II- Forward modelling and inversion techniques, and III - Data processing, analysis, modelling and interpretation. The new edition includes brand new chapters on Pulse and frequency electromagnetic sounding for hydrocarbon offshore exploration. Additionally all other chapters have been extensively updated to include new developments.

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