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Elsevier

Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

  • Advances in Catalysis

    • 1st Edition
    • Volume 62
    • Chunshan Song
    • English
    Advances in Catalysis, Volume 62, fills the gap between journal papers and textbooks across a diverse areas of catalysis research. For more than 60 years, this series has recorded and presented the latest progress in the field of catalysis, providing the scientific community with comprehensive and authoritative reviews. This series is an invaluable and comprehensive resource for chemical engineers and chemists working in the field of catalysis in both academia and industry.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 70
    • Pedro J. Perez
    • English
    Advances in Organometallic Chemistry, Volume 70, contains authoritative review articles of worldwide known researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more. It is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications. Topics of note in this new release include Carbon Dioxide Electroreduction Catalyzed by Organometallic Complexes, Single-electron Elementary Steps in Homogeneous Organometallic Catalysis, Recent advances in catalytic hydrosilylation of carbonyl groups mediated by well-defined first-row late transition metals, and more.

  • Neglected Diseases: Extensive Space for Modern Drug Discovery

    • 1st Edition
    • Volume 51
    • English
    Neglected Diseases: Extensive Space for Modern Drug Discovery provides in-depth reviews on the last progresses about neglected tropical diseases research. Topics covered in this volume include Leishmaniasis, Tripanosomiasis, Onchocerciasis and Ebolavirus infections, with insights on the future of the research on them. Part of the volume is devoted to recent contributions this field received from X-Ray crystallography.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 87
    • English
    Advances in Clinical Chemistry, Volume 87, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Anionic Annulations in Organic Synthesis

    A Versatile and Prolific Class of Ring-Forming Reactions
    • 1st Edition
    • Dipakranjan Mal
    • English
    Anionic Annulations in Organic Synthesis: A Versatile and Prolific Class of Ring-Forming Reactions is a comprehensive review of the main annulations for the construction of cyclic structures and their use in the total synthesis of functional molecules. The book explores in detail the Hauser, Robinson, Sammes, and Myers annulations, all of which are beneficial to constructing substrates with complex molecular structures suitable for pharmaceutical purposes. This volume begins with an in-depth introduction on the history and perspectives of annulations. It then covers different categories of annulation in each chapter, examining their application to drug synthesis for a range of different medicinal compounds. Anionic Annulations in Organic Synthesis delivers a thorough analysis of the topic and provides the tools necessary to master anionic organic chemistry. It is a valuable resource for chemists, researchers, and students seeking a complete and detailed understanding of anionic annulations.

  • Computational Quantum Chemistry

    Insights into Polymerization Reactions
    • 1st Edition
    • Masoud Soroush
    • English
    Computational Quantum Chemistry: Insights into Polymerization Reactions consolidates extensive research results, couples them with computational quantum chemistry (CQC) methods applicable to polymerization reactions, and presents those results systematically. CQC has advanced polymer reaction engineering considerably for the past two decades. The book puts these advances into perspective. It also allows you to access the most up-to-date research and CQC methods applicable to polymerization reactions in a single volume. The content is rigorous yet accessible to graduate students as well as researchers who need a reference of state-of-the-art CQC methods with polymerization applications.

  • Fluorine

    A Paradoxical Element
    • 1st Edition
    • Volume 5
    • Alain Tressaud
    • English
    Fluorine: A Paradoxical Element, Volume Five, deals with the link between fluorine, humanity and the environment. It is divided into three main sections, including i) The history and developmental stages of fluorinated products, ii) Awareness of its importance in our environment, and iii) Recent contributions of fluoride products in medicine, pharmacy and our daily lives. Made engaging through interesting figures and accessible language, and written by a leading expert, Professor Tressaud, the book supports the work of scientists working in materials, toxicology and environmental science. It complements the author’s edited series, Progress in Fluorine Science, covering recent advances.

  • Annual Reports in Computational Chemistry

    • 1st Edition
    • Volume 14
    • David A. Dixon
    • English
    Annual Reports in Computational Chemistry, Volume 14, provides timely and critical reviews of important topics in computational chemistry. Topics covered in this series include quantum chemistry, molecular mechanics, force fields, chemical education, and applications in academic and industrial settings. Focusing on the most recent literature and advances in the field, each article covers a specific topic of importance to computational chemists.

  • The Handbook of Metabolic Phenotyping

    • 1st Edition
    • John C. Lindon + 2 more
    • English
    The Handbook of Metabolic Phenotyping is the definitive work on the rapidly developing subject of metabolic phenotyping. It explores in detail the wide array of analytical chemistry and statistical modeling techniques used in the field, coupled with surveys of the various application areas in human development, nutrition, disease, therapy, and epidemiology to create a comprehensive exploration of the area of study. It covers recent studies that integrate the various -omics data sets to derive a systems biology view. It also addresses current issues on standardization, assay and statistics validation, and data storage and sharing. Written by experts with many years of practice in the field who pioneered many of the approaches widely used today, The Handbook of Metabolic Phenotyping is a valuable resource for postgrads and research scientists studying and furthering the field of metabolomics.

  • Data Analysis for Omic Sciences: Methods and Applications

    • 1st Edition
    • Volume 82
    • English
    Data Analysis for Omic Sciences: Methods and Applications, Volume 82, shows how these types of challenging datasets can be analyzed. Examples of applications in real environmental, clinical and food analysis cases help readers disseminate these approaches. Chapters of note include an Introduction to Data Analysis Relevance in the Omics Era, Omics Experimental Design and Data Acquisition, Microarrays Data, Analysis of High-Throughput RNA Sequencing Data, Analysis of High-Throughput DNA Bisulfite Sequencing Data, Data Quality Assessment in Untargeted LC-MS Metabolomic, Data Normalization and Scaling, Metabolomics Data Preprocessing, and more.

  • Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia

    • 1st Edition
    • Ahmed Al-Harrasi + 3 more
    • English
    Exhibiting a wealth of interesting activities and novel structures, Boswellic acid and the other terpenoids of the genus Boswellia (from which frankincense is derived) are a growing source of interest for the natural product drug discovery community. Chemistry and Bioactivity of Boswellic Acids and Other Terpenoids of the Genus Boswellia presents, in a single volume for the first time, key research into their structures, synthesis and potential as starting points for the development of medicinal agents. Drawing on the authors’ expert knowledge, this volume is an interesting insight into the identification of novel compounds from endemic plant sources, and is a useful tool for all researchers involved in the discovery and development of bioactive structures from natural products.

  • Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevant Substrates

    • 1st Edition
    • Al Postigo
    • English
    Late-Stage Fluorination of Bioactive Molecules and Biologically-Relevan... Substrates reviews how the use of these techniques on compounds with already known and relevant biological activity can provide new pharmaceutical leads with improved medicinal properties. The fluorination strategies discussed take into account both conventional and novel reagents, including nucleophilic, electrophilic, those of a radical nature, and diverse families of organic compounds, such as (hetero) aromatic rings and aliphatic substrates. Drawing on the authors' expert knowledge, this book provides researchers with a broad set of applicable methods to use in their work.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 28
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 28, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. Planar lipid bilayers are widely studied due to their ubiquity in nature. This book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.

  • Nano-inspired Biosensors for Protein Assay with Clinical Applications

    • 1st Edition
    • Genxi Li
    • English
    Nano-inspired Biosensors for Protein Assay with Clinical Applications introduces the latest developments in nano-inspired biosensing, helping readers understand both the fundamentals and frontiers in this rapidly advancing field. In recent decades, there has been increased interest in nano-inspired biosensors for clinical application. Proteins, e.g. antigen-antibody, tumor markers and enzymes are the most important target in disease diagnosis, and a variety of biosensing techniques and strategies have been developed for protein assay. This book brings together all the current literature on the most recent advances of protein analysis and new methodologies in designing new kinds of biosensors for clinical diagnostic use.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 86
    • English
    Advances in Clinical Chemistry, Volume 86, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians and research scientists. The serial discusses the latest and most up-to-date technologies related to the field of clinical chemistry, and is the benchmark for novel analytical approaches in the clinical laboratory.

  • Annual Reports on NMR Spectroscopy

    • 1st Edition
    • Volume 95
    • English
    Annual Reports on NMR Spectroscopy, Volume 95, provides an in-depth accounting of progress in nuclear magnetic resonance (NMR) spectroscopy and its many applications. In recent years, no other technique has gained as much significance. It is used in all branches of science in which precise structural determination is required, and in which the nature of interactions and reactions in solution is being studied. This book has established itself as a premier resource for both specialists and non-specialists who are looking to become familiar with new techniques and applications pertaining to NMR spectroscopy.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 58
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 58, covers the synthesis, testing and recording of the medicinal properties of natural products, providing cutting edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. With the rapid developments in spectroscopic techniques and accompanying advances in high-throughput screening techniques, it has become possible to rapidly isolate and determine the structures and biological activity of natural products, thus opening up exciting opportunities in the field of new drug development in the pharmaceutical industry.

  • Metal-Free Synthetic Organic Dyes

    • 1st Edition
    • Ghodsi Mohammadi Ziarani + 3 more
    • English
    Metal- Free Synthetic Organic Dyes is a comprehensive guide to the synthetic, organic dyes that are classified by their chemical structure. As synthetic dyes are playing an increasingly important role in modern life, with applications in both industry and scientific research, this book provides insights on the many research attempts that have been made to explore new photosensitizers in the development of dye sensitized solar cells (DSCs). These novel photosensitizers have incorporated, within their structure, different organic groups, such as coumarins, cyanines, hemicyanines, indolines, triphenylamines, bis(dimethylfluoreny... aminophenyls, phenothiazines, tetrahydroquinolines... carbazoles, polyenes, fluorenes, and many others. This comprehensive resource contains color figures and schemes for each dye discussed, and is an invaluable resource for organic, inorganic and analytical chemists working in academia and industry.

  • A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces

    • 1st Edition
    • Ajit Sadana + 2 more
    • English
    A Fractal Analysis of Chemical Kinetics with Applications to Biological and Biosensor Interfaces analyzes the kinetics of binding and dissociation of different analytes by different biosensor techniques, demonstrating, and then comparing each other. Emphasis is on newer instrumentation techniques, such as surface plasmon resonance imaging (SPRi), and classical techniques, such as surface plasmon resonance (SPR), and finally, DNA biosensors and nanobiosensors. In addition, the closing chapter includes discussion of biosensor economics.

  • The Alkaloids

    • 1st Edition
    • Volume 80
    • English
    The Alkaloids, Volume 80, is the newest release in a series that has covered the topic for more than 60 years. As the esteemed, leading reference in the field of alkaloid chemistry, this series covers all aspects of alkaloids, including their chemistry, biology and pharmacology. Sections are presented as high-quality, timeless reviews written by renowned experts in the field, with this new release focusing on pyrrolizidine alkaloids.

  • Alteration of Ovoproducts

    From Metabolomics to Online Control
    • 1st Edition
    • Olivier Goncalves + 1 more
    • English
    Characterizing the Alteration of Ovoproducts Using New Analytical Approaches focuses on the capabilities (potential or proven) of the latest metabolomics based analytical approaches for the (early) diagnostic of the alteration of ovoproducts during their production/preservat... processes. It details the ovoproduct matrix, their known sources of biotic and abiotic alteration, and their associated biomarkers. In addition, the book covers the capabilities (exploratory and characterization) of the latest metabolomics tecnics, both invasive and non-invasive, including chromatography, nuclear magnetic resonance, mass spectrometry, NMR, MS – including FTICR-MS –, and vibrational spectroscopy, such as Infrared – MIR, NIR – or Raman). In final sections, the next generation of online sensors derived from the latest technics is discussed for their applicative potential in industry (NIR, Raman, chromatography, benchmark NMR, and more).

  • Analytical Methods for Food Safety by Mass Spectrometry

    Volume I Pesticides
    • 1st Edition
    • Guo-Fang Pang
    • English
    Analytical Methods for Food Safety by Mass Spectrometry, Volume One: Pesticides systematically introduces the Pesticide and Veterinary Drug Multiresidues Analytical Methods. Volume One includes discussions on 20 pesticide multiresidues chromatic-MS (GC-MS and LC-MS/MS) analytical techniques that have the capability of detecting over 800 pesticides and chemicals in 10 categories of agricultural products, including fruits, vegetables, grains, teas, Chinese medicinal herbs, edible fungus mushrooms, fruit and vegetable juices, animal tissues, aquatic products, raw milk and milk powders, and drinkable water. This book also includes chromatic-MS analytical parameters, linear equations and GPC chromatic behavior parameters for over 800 pesticides. This valuable book can be used as reference for not only university students, but also technical personnel of different specialties who are engaged with study and applications, such as food safety, agricultural environment protection, pesticide development, and utilization in scientific research units, institutions and quality inspection organizations.

  • Physical Chemistry

    Multidisciplinary Applications in Society
    • 1st Edition
    • Kenneth S Schmitz
    • English
    The advancements in society are intertwined with the advancements in science. To understand how changes in society occurred, and will continue to change, one has to have a basic understanding of the laws of physics and chemistry. Physical Chemistry: Multidisciplinary Applications in Society examines how the laws of physics and chemistry (physical chemistry) explain the dynamic nature of the Universe and events on Earth, and how these events affect the evolution of society (multidisciplinary applications). The ordering of the chapters reflects the natural flow of events in an evolving Universe: Philosophy of Science, the basis of the view that natural events have natural causes - Cosmology, the origin of everything from the Big Bang to the current state of the Universe - Geoscience, the physics and chemistry behind the evolution of the planet Earth from its birth to the present - Life Science, the molecules and mechanisms of life on Earth - Ecology, the interdependence of all components within the Ecosphere and the Universe - Information Content, emphasis on how words and phrases and framing of issues affect opinions, reliability of sources, and the limitations of knowledge.

  • Principles and Applications of Molecular Diagnostics

    • 1st Edition
    • Nader Rifai + 3 more
    • English
    Principles and Applications of Molecular Diagnostics serves as a comprehensive guide for clinical laboratory professionals applying molecular technology to clinical diagnosis. The first half of the book covers principles and analytical concepts in molecular diagnostics such as genomes and variants, nucleic acids isolation and amplification methods, and measurement techniques, circulating tumor cells, and plasma DNA; the second half presents clinical applications of molecular diagnostics in genetic disease, infectious disease, hematopoietic malignancies, solid tumors, prenatal diagnosis, pharmacogenetics, and identity testing. A thorough yet succinct guide to using molecular testing technology, Principles and Applications of Molecular Diagnostics is an essential resource for laboratory professionals, biologists, chemists, pharmaceutical and biotech researchers, and manufacturers of molecular diagnostics kits and instruments.

  • Key Heterocycle Cores for Designing Multitargeting Molecules

    • 1st Edition
    • Om Silakari
    • English
    Key Heterocycle Cores for Designing Multitargeting Molecules provides a helpful overview of current developments in the field. Following a detailed introduction to the manipulation of heterocycle cores for the development of dual or multitargeting molecules, the book goes on to describe specific examples of such developments, focusing on compounds such as Benzimidazole, Acridine, Flavones, Thiazolidinedione and Oxazoline. Drawing on the latest developments in the field, this volume provides a valuable guide to current approaches in the design and development of molecules capable of acting on multiple targets. Adapting the heterocyclic core of a single-target molecule can facilitate its development into an agent capable of acting on multiple targets. Such multi-targeting drugs have the potential to become essential components in the design of novel, holistic treatment plans for complex diseases, making the design of such active agents an increasingly important area of research.

  • Chemical Sciences in Early Drug Discovery

    Medicinal Chemistry 2.0
    • 1st Edition
    • Pierfausto Seneci
    • English
    Chemical Sciences in Early Drug Discovery: Medicinal Chemistry 2.0 describes how new technologies and approaches can be used to improve the probability of success in fulfilling the perennial goal of finding and developing new drugs. Drawing on the author's extensive experience consulting and teaching in medicinal chemistry, the book outlines ways in which medicinal chemistry is widening its reach to meet modern demands, and how modern technologies and approaches are facilitating this growth into new fields. Supported by examples throughout, the book is a practical resource for organic-medicinal chemists, biological chemists and pharmacologists involved in drug discovery.

  • Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides

    • 1st Edition
    • Anant R. Kapdi + 2 more
    • English
    Palladium-Catalyzed Modification of Nucleosides, Nucleotides and Oligonucleotides describes the procedures and protocols related to the modification of nucleosides, nucleotides and oligonucleotides via Pd-mediated cross-coupling processes. The book highlights the growing area of nucleic acid modification and how Pd-mediated coupling reactions can assist this development. Users will find key synthetic protocols for these reactions in this latest volume in the Latest Trends in Palladium Chemistry series. As most of the research in the field of antiviral agents has centered on the use of modified nucleosides that have exhibited promising activity, this book provides an up-to-date reference for both professionals in industry and other interested parties.

  • Physical Chemistry of Gas-Liquid Interfaces

    • 1st Edition
    • Jennifer A. Faust + 1 more
    • English
    Physical Chemistry of Gas-Liquid Interfaces, the first volume in the Developments in Physical & Theoretical Chemistry series, addresses the physical chemistry of gas transport and reactions across liquid surfaces. Gas–liquid interfaces are all around us, especially within atmospheric systems such as sea spry aerosols, cloud droplets, and the surface of the ocean. Because the reaction environment at liquid surfaces is completely unlike bulk gas or bulk liquid, chemists must readjust their conceptual framework when entering this field. This book provides the necessary background in thermodynamics and computational and experimental techniques for scientists to obtain a thorough understanding of the physical chemistry of liquid surfaces in complex, real-world environments.

  • Chiral Analysis

    Advances in Spectroscopy, Chromatography and Emerging Methods
    • 2nd Edition
    • P.L. Polavarapu
    • English
    Chiral Analysis: Advances in Spectroscopy, Chromatography and Emerging Methods, Second Edition covers an important area of analytical chemistry of relevance to a wide variety of scientific professionals, including chemistry graduate students, analytical chemists, organic chemists, professionals in the pharmaceutical industry, and others with an interest in chirality and chiral analysis. This thoroughly revised second edition covers several new, important areas of chiral analysis that have emerged since the first edition. Three of the new methods provide higher sensitivity than can be realized with the current methods and are expected to become mainstream applications: cavity based methods offer vastly higher sensitivity than conventional polarimetric methods, microwave chiral detection provides unsurpassed sensitivity for identifying diastereomers, and the rotating electric field method offers a competing new approach for the separation of enantiomers. Another topic, chirality in extraterrestrial life, has not been discussed in any other book and is important for understanding the origin of life.

  • Biological Inorganic Chemistry

    A New Introduction to Molecular Structure and Function
    • 3rd Edition
    • Robert R. Crichton
    • English
    Biological Inorganic Chemistry: A New Introduction to Molecular Structure and Function, Third Edition, provides a comprehensive discussion of the biochemical aspects of metals in living systems. The fascinating world of the role of metals in biology, medicine and the environment has progressed significantly since the very successful Second Edition of the book published in 2012. Beginning with an overview of metals and selected nonmetals in biology, the book supports the interdisciplinary nature of this vibrant area of research by providing an introduction to basic coordination chemistry for biologists and structural and molecular biology for chemists. Having built this accessible foundation, the book progresses to discuss biological ligands for metal ions, intermediary metabolism and bioenergetics, and methods to study metals in biological systems. The book also covers metal assimilation pathways; transport, storage, and homeostasis of metal ions; sodium and potassium channels and pumps; magnesium phosphate metabolism and photoreceptors; calcium and cellular signaling; the catalytic role of several classes of mononuclear zinc enzymes; the biological chemistry of iron; and copper chemistry and biochemistry. In addition, the book discusses nickel and cobalt enzymes; manganese chemistry and biochemistry; molybdenum, tungsten, vanadium, and chromium; non-metals in biology; biomineralization; metals in the brain; metals and neurodegeneration; metals in medicine and metals as drugs; and metals in the environment. Now in its Third Edition, this popular and award-winning resource highlights recent exciting advances and provides a thorough introduction for both researchers approaching the field from a variety of backgrounds, as well as advanced students.

  • Advances in Organometallic Chemistry

    • 1st Edition
    • Volume 69
    • English
    Advances in Organometallic Chemistry, Volume 69, contains authoritative review articles of world renowned researchers in the field of organometallic chemistry. This longstanding serial is known for its comprehensive coverage of topics in organometallic synthesis, reactions, mechanisms, homogeneous catalysis, and more, with this release focusing on topics such as C-H Activation Mediated by Main Group Inorganic and Organometallic Compounds, Transition-metals catalyzed intramolecular amination and hydroamination reactions of allenes, Green Fluorescent Protein-like and related organometallic fluorophores, Recent advances in the synthesis of C-­ S-­ bonds via metal‐catalyzed functionalization of C‐ H‐ bonds, Current mechanistic understanding of Co-catalyzed C-H functionalization, and more. The book is ideal for a wide range of researchers involved in organometallic chemistry, including synthetic protocols, mechanistic studies and practical applications.

  • Advances in Heterocyclic Chemistry

    • 1st Edition
    • Volume 126
    • English
    Advances in Heterocyclic Chemistry, Volume 126, is the definitive series in the field, one that is of great importance to organic chemists, polymer chemists and many biological scientists. Because biology and organic chemistry increasingly intersect, the associated nomenclature is used more frequently in explanations. Updates to this release include sections on The Literature of Heterocyclic Chemistry, Part XVI, 2016, The preparation and properties of heteroarylazulenes and hetero-fused azulenes, Recent developments in pyrazole chemistry, Yne, Ene-Yne Synthetic Approaches to Heterocycles, Appel Salt and Heterocycles: A review of Thirty Years of 4,5-Dichloro-1,2,3-d... Chloride Chemistry, and more. Written by established authorities in the field, this comprehensive review combines descriptive synthetic chemistry and mechanistic insight to yield an understanding on how chemistry drives the preparation and useful properties of heterocyclic compounds.

  • Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors

    • 1st Edition
    • Volume 81
    • English
    Fundamentals of Quorum Sensing, Analytical Methods and Applications in Membrane Bioreactors, Volume 81, describes the novelty of membrane bioreactors for the treatment of wastewater and the removal of specific contaminants that affect water quality or pose harm to humans. Topics of note in the updated release include Water Chemistry and Microbiology, Quorum Sensing as Bacterial Communication Language, the Effects of Quorum Sensing, Quorum Quenching, Membrane Bioreactors for Wastewater Treatment, Removal of Specific Contaminants, Microextraction Techniques, and the Determination of Quorum Sensing Chemicals. The contents of this updated volume will be appealing to a wide range of researchers as the authors of most chapters are experts in their respective fields with numerous published studies.

  • Advances in Transition-Metal Mediated Heterocyclic Synthesis

    • 1st Edition
    • Daniel Sole + 1 more
    • English
    Advances in Transition-Metal Mediated Heterocyclic Synthesis provides an overview of recent catalytic reactions involving transition metals to produce heterocyclic compounds. The book is organized according to the type of transformation used to achieve the synthesis of the heterocyclic systems (mainly aza- and oxa-heterocycles). As such, it covers recent applications on the synthesis of heterocycles, also describing the details of the novel transformations in a didactic manner to motivate readers in search of new catalytic processes. The editors have included state-of-the-art strategies, including transition-metal reactions involving unsaturated systems (reactions of allenes, new gold(I)-catalyzed reactions, and Prins reaction). Chapters highlight the versatility of organopalladium chemistry dealing with carbonylative transformations, C-H activation reactions, coupling processes, and the control of the ambiphilic character of organopalladium species. Finally, the book discusses new reactions leading to heterocycles based on C-H activation processes catalyzed by other metals (Rh, Ru, Co). Written by an outstanding team of authors who are leading experts in organometallic chemistry and organic synthesis, this book is a valuable resource not only for chemists mainly focused on synthesis, but also for those interested in reaction mechanisms involving transition metals.

  • Vibrational Spectroscopy for Plant Varieties and Cultivars Characterization

    • 1st Edition
    • Volume 80
    • English
    Vibrational Spectroscopy for Plant Varieties and Cultivars Characterization, Volume 80, provides an overview on the application of vibrational spectroscopy to characterize plant cultivars and varieties. It covers a variety of aspects, including the potential of this technique for taxonomic purposes (species and cultivars/varieties identification), how to discriminate plants according to their ages and geographic regions, how to depict soil properties through plant characteristics, etc. Currently, most of these studies are performed through somewhat laborious techniques. This book presents reliable alternatives to such techniques, while also systematizing information concerning the application of vibration spectroscopy in this context.

  • Computational Phytochemistry

    • 1st Edition
    • Satyajit Dey Sarker + 1 more
    • English
    Computational Phytochemistry explores how recent advances in computational techniques and methods have been embraced by phytochemical researchers to enhance many of their operations, thus refocusing and expanding the possibilities of phytochemical studies. By applying computational aids and mathematical models to extraction, isolation, structure determination and bioactivity testing, researchers can extract highly detailed information about phytochemicals and optimize working approaches. This book aims to support and encourage researchers currently working with, or looking to incorporate, computational methods into their phytochemical work. Topics in this book include computational methods for predicting medicinal properties, optimizing extraction, isolating plant secondary metabolites and building dereplicated phytochemical libraries. The role of high-throughput screening, spectral data for structural prediction, plant metabolomics and biosynthesis are all reviewed, before the application of computational aids for assessing bioactivities and virtual screening are discussed. Illustrated with detailed figures and supported by practical examples, this book is an indispensable guide for all those involved with the identification, extraction and application of active agents from natural products.

  • Rheology of Emulsions

    Electrohydrodynamics Principles
    • 1st Edition
    • Volume 22
    • Aleksandar M. M. Spasic
    • English
    Rheology of Emulsions, Volume 22: Electrohydrodynamics Principles studies phenomena at liquid-liquid interfaces, including finely dispersed particles or structures, in particular emulsions, double emulsions and biological cells. The book considers the forces of electrical origin that participate in the physical events at liquid-liquid interfaces, taking into account electron transfer phenomenon and electrodynamics principles. Topics covered are of interest to a broad range of scientists, researchers and graduate students with a basic knowledge of physical chemistry, electromagnetism, fluid mechanics, classical and quantum electrodynamics. The implications and applications of the material presented in the book contribute to the advanced fundamental, applied and engineering research of interfacial electroviscoelastic phenomena.

  • Profiles of Drug Substances, Excipients, and Related Methodology

    • 1st Edition
    • Volume 43
    • Harry G. Brittain
    • English
    Profiles of Drug Substances, Excipients, and Related Methodology, Volume 43 presents comprehensive reviews of drug substances and additional materials, with critical review chapters that summarize information related to the characterization of drug substances and excipients. The series encompasses review articles and database compilations that fall within a variety of categories, with this release focusing on Ganciclovir, Mirtazapine, Tolfenamic Acid, Mid-Infrared Spectroscopy of Pharmaceutical Solids, and the Validation of Chromatographic Methods of Analysis: Application for drugs that derived from herbs.

  • Synthesis of Medicinal Agents from Plants

    • 1st Edition
    • Ashish Kumar Tewari + 1 more
    • English
    Synthesis of Medicinal Agents from Plants highlights the importance of synthesizing medicinal agents from plants and outlines methods for performing it effectively. Beginning with an introduction to the significance of medicinal plants, the book goes on to provide a historical overview of drug synthesis before exploring how this can be used to successfully replicate and adapt the active agents from natural sources. Chapters then explore the medicinal properties of a number of important plants, before concluding with a discussion of the future of drugs from medicinal plants. Illustrated with real-world examples, it is a practical resource for researchers in this field. In an age of rapid environmental destruction, hundreds of medicinal plants are at risk of extinction from overexploitation and deforestation, limiting the natural resources available for active agent extraction, thereby threatening the discovery of future cures for diseases. Simultaneously, with the increasing population and advances in medical sciences, the demand for drugs is continuously increasing and cannot be met with just plants. The ability to synthetically replicate the active compounds from these plants is essential in creating an ecologically-aware, sustainable future for drug design

  • Direct Synthesis of Metal Complexes

    • 1st Edition
    • B.I. Kharisov
    • English
    Direct Synthesis of Metal Complexes provides in-depth coverage of the direct synthesis of coordination and organometallic compounds. The work is primarily organized by methods, but also covers highly relevant complexes, such as metal-polymer coordination compounds. This updated reference discusses recent developments in cryosynthesis, electrosynthesis, and tribosynthesis (popular as it doesn’t require organic solvents), with special attention paid to ‘greener’ methodologies and approaches. Additionally, the book describes physical methods of zero-valent metal interaction with organic matter, including sputtering, ultrasonic treatment and synthesis in ionic liquids. The book presents completely new content as a follow-up to the 1999 Elsevier Science publication Direct Synthesis of Coordination and Organometallic Compounds that was edited by Dr. Garnovskii and Dr. Kharisov.

  • Studies in Natural Products Chemistry

    • 1st Edition
    • Volume 57
    • Atta-ur Rahman
    • English
    Studies in Natural Products Chemistry, Volume 57, covers rapid developments in spectroscopic techniques and advances in high-throughput screening techniques that have made it possible to rapidly isolate and determine the structures and biological activity of natural products in new drug development. The series also covers the synthesis of the medicinal properties of natural products, providing cutting-edge accounts of fascinating developments in the isolation, structure elucidation, synthesis, biosynthesis and pharmacology of a diverse array of bioactive natural products. Specific sections in this release cover broad-spectrum health protection of extra virgin olive oil compounds, synthesis of cardiac steroids and their role on heart failure and cancer, and more.

  • Capillary Electromigration Separation Methods

    • 1st Edition
    • Colin F. Poole
    • English
    Capillary Electromigration Separation Methods is a thorough, encompassing reference that not only defines the concept of contemporary practice, but also demonstrates its implementation in laboratory science. Chapters are authored by recognized experts in the field, ensuring that the content reflects the latest developments in research. Thorough, comprehensive coverage makes this the ideal reference for project planning, and extensive selected referencing facilitates identification of key information. The book defines the concept of contemporary practice in capillary electromigration separation methods, also discussing its applications in small mass ions, stereoisomers, and proteins.

  • Pincer Compounds

    Chemistry and Applications
    • 1st Edition
    • David Morales-Morales
    • English
    Pincer Compounds: Chemistry and Applications offers valuable state-of-the-art coverage highlighting highly active areas of research—from mechanistic work to synthesis and characterization. The book focuses on small molecule activation chemistry (particularly H2 and hydrogenation), earth abundant metals (such as Fe), actinides, carbene-pincers, chiral catalysis, and alternative solvent usage. The book covers the current state of the field, featuring chapters from renowned contributors, covering four continents and ranging from still-active pioneers to new names emerging as creative strong contributors to this fascinating and promising area. Over a decade since the publication of Morales-Morales and Jensen’s The Chemistry of Pincer Compounds (Elsevier 2007), research in this unique area has flourished, finding a plethora of applications in almost every single branch of chemistry—from their traditional application as very robust and active catalysts all the way to potential biological and pharmaceutical applications.

  • Himalayan Phytochemicals

    Sustainable Options for Sourcing and Developing Bioactive Compounds
    • 1st Edition
    • Sumira Jan + 1 more
    • English
    Himalayan Phytochemicals: Sustainable Options for Sourcing and Developing Bioactive Compounds provides a detailed review of the important medicinal plants which have already been discovered in the Himalayan region, outlining their discovery, activity and underlying chemistry. In addition, it supports a global shift towards sustainable sourcing of natural products from delicate ecosystems. Across the world, environmental destruction and overharvesting of medicinal plants are reducing and destroying multiple important sources and potential leads before researchers have the chance to discover, explore or synthesize them effectively. By identifying this problem and discussing its impact on the Himalayan region, Himalayan Phytochemicals: Sustainable Options for Sourcing and Developing Bioactive Compounds frames the ongoing global struggle and highlights the key factors that must be considered and addressed when working with phytochemicals from endemic plant sources.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 57
    • English
    Progress in Medicinal Chemistry, Volume 57, provides a review of eclectic developments in medicinal chemistry, with this volume including chapters on the CaSR field, CFTR modulators in cystic fibrosis, macrocycles, VMAT2 inhibitors, and Big Data in Drug Discovery.

  • Pericyclic Chemistry

    Orbital Mechanisms and Stereochemistry
    • 1st Edition
    • Dipak Kumar Mandal
    • English
    Pericyclic Chemistry: Orbital Mechanisms and Stereochemistry is a complete guide to the topic that is ideal for graduate students, advanced undergraduate students and researchers in organic chemistry. An introduction to molecular orbital theory and relevant stereochemical concepts is provided as background, with all four classes of pericyclic reactions discussed and illustrated with orbital picture representations. Also included are chapters on cycloadditions, the most versatile class, and electrocyclic reactions, sigmatropic rearrangements and group transfer reactions. A separate chapter on the construction of correlation diagrams is also included, emphasizing a practical, hands on approach. Author Dipak Kumar Mandal brings over 30 years of teaching experience to the topic and illuminates pericyclic chemistry with a clear and fresh perspective.

  • Vicinal Diaryl Substituted Heterocycles

    A Gold Mine for the Discovery of Novel Therapeutic Agents
    • 1st Edition
    • M. R. Yadav + 2 more
    • English
    Vicinal Diaryl-Substituted Heterocycles: A Gold Mine for the Discovery of Novel Therapeutic Agents draws together all of the key information about these compounds in one place for the first time. Following an informative overview of the importance of these structures to the discovery of potential therapeutic agents, the text goes on to outline the main compound types, with each chapter focusing on the activities of a different structure. Designed to support researchers by consolidating this important information in a single, practical guide, the authors hope to encourage further advancement and development in the discovery of novel therapeutic agents. As flexible building blocks for the production of novel compounds, vicinal diaryl-substituted heterocycles are a rich source of leads for the development of new drugs. Their adaptability means that they can be used to produce structures with a broad range of attractive characteristics, and a large number of vicinal diaryl-substituted heterocyclic compounds have already been synthesized and investigated by medicinal chemists as promising lead molecules.

  • Catalytic Amination for N-Alkyl Amine Synthesis

    • 1st Edition
    • Feng Shi + 1 more
    • English
    Catalytic Amination for N-Alkyl Amine Synthesis provides a useful survey of this key type of reaction for chemistry researchers in academia and industry. Beginning with an introduction to amination and the development of the field, the book focuses on useful and high potential methods, such as the catalytic amination of alcohol with homogeneous and heterogeneous catalysts, the coupling reaction of olefin and amine, and the reductive amination of carbon dioxide with different reducing agents. The work also discusses two key examples of one-pot synthesis, the oxidative amination of alkane and amine and synthesis of N-alkyl amine with nitrobenzene and nitrile as starting materials. Valuable for chemists, materials scientists, chemical engineers and others, the book offers a unique overview of this growing area and its future possibilities.

  • The Chemistry of Titanium, Zirconium and Hafnium

    Pergamon Texts in Inorganic Chemistry
    • 1st Edition
    • R. J. H. Clark + 2 more
    • English
    The Chemistry of Titanium, Zirconium and Hafnium deals with the chemistry of titanium, zirconium, and hafnium and covers topics ranging from the occurrence and metallurgy of all three elements to their nuclear, physical, and chemical properties as well as analytical chemistry. The compounds of titanium, zirconium, and hafnium are also discussed. This volume is comprised of two chapters and opens with a historical overview and discovery of titanium, along with its occurrence and distribution, metallurgical aspects, and nuclear and physicochemical properties. The compounds of titanium are also considered, including alloys and complexes; hydrides and oxides; halides and oxyhalides; titanates and antimonides; and carbides and borides. The second chapter is devoted to zirconium and hafnium, their occurrence and metallurgy; and physical, chemical, and biological properties. Compounds of zirconium and hafnium are described, from alloys and hydrides to zirconates and hafnates; nitrides, phosphides, and arsenides; carbides, silicides, and germanides; molybdates, tungstates, halates, and perchlorates; alkoxides, mercaptides, and dithiocarbamates; and amides, alkylamides, triazenes, phthalocyanines, and bipyridyls. This book will be a valuable source of information for inorganic chemists.

  • Chemical Transformations of Polymers

    • 1st Edition
    • R. Rado
    • English
    Chemical Transformations of Polymers provides information pertinent to the fundamental structure and aspects of the chemical transformation of polymers. This book examines several experiments for the chemical transformation of polymers, which start from the assumption that the reactivity of a functional group in a macromolecule has to be similar as one in a low molecular compound. Organized into 19 chapters, this book begins with an overview of the various photochromic systems that have been used in polymer chemistry. This text then examines the three types of stable polymers with unpaired electrons, including polyradical ions, neutral polyradicals, and polymeric charge transfer complexes. Other chapters consider the kinetic laws and traits of migration mechanisms of free valence in the process of decay of free radicals in polymers. The final chapter deals with the complicated reaction of the degradation of polymers induced by the presence of metal compounds. This book is a valuable resource for chemists, scientists, and physiochemical researchers.

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