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Books in Chemistry

Chemistry topic areas include: physical and theoretical, computational, organic, organometallic and inorganic, pharmaceutical and medicinal, analytical and bioanalytical, nuclear, general, nanochemistry, geochemistry, materials and polymer, as well as environmental, green and sustainable chemistry.

    • Advances in Medicinal Chemistry

      • 1st Edition
      • Volume 4
      • April 1, 1999
      • B.E. Maryanoff + 1 more
      • English
      • Hardback
        9 7 8 0 7 6 2 3 0 0 6 4 8
      • Paperback
        9 7 8 0 4 4 4 5 4 6 4 9 4
      • eBook
        9 7 8 0 0 8 0 5 2 6 3 7 9
      Volume 4 of Advances in Medicinal Chemistry is comprised of six chapters on a wide range of topics in medicinal chemistry, including molecular modeling, structure-based drug design, organic synthesis, peptide conformational analysis, biological assessment, structure-activity correlation, and lead optimization. Chapter 1 presents an account about amino acid-based peptide mimetics corresponding to b-turn, loop, helical motifs in proteins as a probe of ligand-receptor and ligand-enzyme molecular interactions. Chapter 2 addresses new facets of the medicinal chemistry of the important anticancer drug Taxol® (paclitaxel). Chapter 3 relates an account of the search for new drugs for the treatment of malaria based on the natural product artemisinin. Chapter 4 applies computational chemistry to the evaluation of compound libraries for biological testing. Chapter 5 describes the construction of a 3-dimensional molecular model of the human thrombin receptor, the first protease-activated G-protein coupled receptor (PAR-1), as a means to explore the intermolecular contacts involved in agonist peptide recognition. Finally, Chapter 6 describes the research conducted at Merck on inhibitors of farnesyl transferase as a potential treatment for human cancers.
    • Protein Liquid Chromatography

      • 1st Edition
      • Volume 61
      • December 13, 1999
      • M. Kastner
      • English
      • Paperback
        9 7 8 0 4 4 4 5 0 2 1 1 7
      • eBook
        9 7 8 0 0 8 0 9 2 9 2 4 8
      • eBook
        9 7 8 0 0 8 0 8 5 8 6 9 2
      Protein Liquid Chromatography is a handbook-style guide to liquid chromatography as a tool for isolating and purifying proteins, consisting of 25 individual chapters divided into three parts: Part A covers commonly-used, classic modes of chromatography such as ion-exchange, size-exclusion, and reversed-phase; Part B deals with various target protein classes such as membrane proteins, recombinant proteins, and glycoproteins; and Part C looks at various miscellaneous related topics, including coupling reaction, buffer solution additives, and software. The text as a whole can be viewed as a systematic survey of available methods and how best to use them, but also attempts to provide an exhaustive coverage of each facet. How to solve a specific problem using a chosen method is the overall essence of the volume. The principle philosophy of this compilation is that practical application is everything; therefore, both classical and modern methods are presented in detail, with examples involving conventional, medium- and high-pressure techniques. Over-exposure to history, concept, and theory has deliberately been avoided. The reader will find a wealth of tips and tricks from users for users, including advice on the advantages and disadvantages of each method. Easy-to-read sections on "Getting started now" and "Where to go from here" attempt to provide hands-on, fool-proof detailed practical procedures with complete and even standard model runs for any scientist or technician at work in this area.
    • Experiments in Catalytic Reaction Engineering

      • 1st Edition
      • Volume 124
      • August 11, 1999
      • J.M. Berty
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 1 3 7 6
      • eBook
        9 7 8 0 0 8 0 5 3 1 4 2 7
      The science of catalytic reaction engineering studies the catalyst and the catalytic process in the laboratory in order to predict how they will perform in production-scale reactors. Surprises are to be avoided in the scaleup of industrial processes. The laboratory results must account for flow, heat and mass transfer influences on reaction rate to be useful for scaleup. Calculated performance based on these results must also be useful to maximization of profit and safety and minimization of pollution. To this end, information on products as well as byproducts and heat produced must be generated. If a sufficiently large database of knowledge is produced, optimization studies will be possible later if economic conditions change.The field of reaction engineering required new tools. For kinetic and catalyst testing, the most successful of these tools was the internal recycle reactor. Studies in recycle reactors can be made under well-defined conditions of flow and associated transfer processes, and close to commercial operation. The recycle reactor eliminates or minimizes the effect of transfer process, and allows the remaining ones to be known.Features of this book:• Provides insight into a field that is neither well understood nor properly appreciated.• Gives a deeper understanding of reaction engineering practice.• Helps avoid frustration and disappointment in industrial research. This book is short and clear enough to assist all members of the R&D and Engineering team, whether reaction engineers, or specialists in other fields. This is critical in this new age of computation and communication, when team members must each know at least something of their colleagues' fields. Additionally, many scientists in more exploratory or fundamental fields can use recycle reactors to study basic phenomena free of transfer interactions.
    • Progress in Heterocyclic Chemistry

      • 1st Edition
      • Volume 11
      • August 12, 1999
      • G.W. Gribble + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 2 5 1 9
      • eBook
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      This volume of Progress in Heterocyclic Chemistry (PHC) is the eleventh annual review of the literature, covering the work published on most of the important heterocyclic ring systems during 1998, with inclusions of earlier materials as appropriate. In addition, this year there are three specialized reviews. Martine Demeunynck and Arnaud Tatibouët present recent chemistry of Tröger's Base in Chapter 1. Pedro Merino reviews the reactions of metalated heterocycles with carbonyl compounds in Chapter 2. John Joule summarizes the remarkable nucleophilic substitution chemistry on the indole five-membered ring in Chapter 3. The subsequent chapters deal with recent advances in the field of heterocyclic chemistry arranged by increasing ring size and with emphasis on synthesis and reactions. Due to the ever increasing amount of material to be surveyed, the authors were encouraged to provide selective and critical reviews of the more significant papers where space does not allow comprehensive coverage.
    • Biosensors: A Chinese Perspective

      • 1st Edition
      • Volume 4
      • April 30, 1999
      • Reinhard Renneberg + 1 more
      • English
      • Hardback
        9 7 8 0 7 6 2 3 0 0 7 3 0
      In this second volume of a sub-series dedicated to regional activities, eminent authorities form China in the field of biosensors provide an up-to-date overview of their laboratory's contribution, summarizing the primary research as it has appeared, possibly scattered, in the journal and conference literature and reflecting on their findings. This produces an innovative synthesis of such smaller research efforts into an overall perspective on the topic, which is difficult for the reader to glean from the multifarious original publications often available only in Chinese. There is latitude for the inclusion of detail that may have been excised from the original publication and for speculation on future possibilities. The net result is intense, yet highly readable accounts of the state of the art at this leading edge of analytical technology in this key region of the world.This is the first book in the English language summarizing biosensor and bioelectronics efforts in China.
    • Annual Reports on NMR Spectroscopy

      • 1st Edition
      • Volume 35
      • March 27, 1998
      • English
      • eBook
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      Volume 35 reflects the new diverse utilization of NMR Spectroscopy, with four papers from very different areas of the field. These papers include not only recent developments in NMR but also its wide-ranging applications.
    • Advances in Metal and Semiconductor Clusters

      • 1st Edition
      • Volume 4
      • July 27, 1998
      • M.A. Duncan
      • English
      • Hardback
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      Cluster Materials is the fourth volume of the highly successful series Advances in Metal and Semiconductor Clusters. In this volume the focus is on the properties of clusters which determine their potential applications as new materials. Metal and semiconductor clusters have been proposed as precursors for materials or as actual materials since the earliest days of cluster research. In the last few years, a variety of techniques have made it possible to produce clusters in sizes varying from a few atoms up to several thousand atoms. While some measurements are performed in the gas phase on non-isolated clusters, many cluster materials can now be isolated in macroscopic quantities and more convenient studies of their properties become possible. In this volume the authors focus on measurement of optical, electronic, magnetic, chemical and mechanical properties of clusters or of cluster assemblies. All of these properties must fall into acceptable ranges of behaviour before useful materials composed of clusters can be put into practical applications. As evidenced by the various work described here, the realisation of practical products based on cluster materials seems to be approaching rapidly.
    • Advances in Carbohydrate Chemistry and Biochemistry

      • 1st Edition
      • Volume 53
      • July 31, 1998
      • English
      This volume is one of a series providing critical articles by research specialists in the industrial, analytical and technological aspects of biochemistry, organic chemistry and instrumentation methodology.
    • Annual Reports on NMR Spectroscopy

      • 1st Edition
      • Volume 36
      • May 12, 1998
      • English
      • eBook
        9 7 8 0 0 8 0 5 8 4 1 9 5
      This volume has brings together three examples of leading work in the field of NMR Spectroscopy. The contributions show very different applications of spectroscopy, which serve to highlight its importance in an ever increasing number of fields, pure and applied.