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Books in Life sciences

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    • The Design and Manufacture of Medical Devices

      • 1st Edition
      • October 16, 2012
      • J. Paulo Davim + 1 more
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 7 2 5
      • eBook
        9 7 8 1 9 0 8 8 1 8 1 8 8
      Medical devices play an important role in the field of medical and health technology, and encompass a wide range of health care products. Directive 2007/47/EC defines a medical device as any instrument, apparatus, appliance, software, material or other article, whether used alone or in combination, including the software intended by its manufacturer to be used specifically for diagnostic and/or therapeutic purposes and necessary for its proper application, intended by the manufacturer to be used for human beings. The design and manufacture of medical devices brings together a range of articles and case studies dealing with medical device R&D. Chapters in the book cover materials used in medical implants, such as Titanium Oxide, polyurethane, and advanced polymers; devices for specific applications such as spinal and craniofacial implants, and other issues related to medical devices, such as precision machining and integrated telemedicine systems.

    • The Neuroscience of Autism Spectrum Disorders

      • 1st Edition
      • October 25, 2012
      • Joseph D. Buxbaum + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 9 2 4 3
      • eBook
        9 7 8 0 1 2 3 9 1 9 3 0 4
      Autism is no longer considered a rare disease, and the Center for Disease Control now estimates that upwards of 730,000 children in the US struggle with this isolating brain disorder. New research is leading to greater understanding of and ability to treat the disorder at an earlier age. It is hoped that further genetic and imaging studies will lead to biologically based diagnostic techniques that could help speed detection and allow early, more effective intervention. Edited by two leaders in the field, this volume offers a current survey and synthesis of the most important findings of the neuroscience behind autism of the past 20 years. With chapters authored by experts in each topic, the volume explores etiology, neuropathology, imaging, and pathways/models. Offering a broad background of ASDs with a unique focus on neurobiology, the volume offers more than the others on the market with a strictly clinical focus or a single authored perspective that fails to offer expert, comprehensive coverage. Researchers and graduate students alike with an interest in developmental disorders and autism will benefit, as will autism specialists across psychology and medicine looking to expand their expertise.

    • Advances in Parasitology

      • 1st Edition
      • Volume 83
      • December 2, 2012
      • English
      • eBook
        9 7 8 0 1 2 4 0 7 7 3 3 1
      First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2011 impact factor is 4.39.

    • Methods of Enzymatic Analysis V2

      • 2nd Edition
      • December 2, 2012
      • Hans-UIrich Bergmeyer
      • English
      • Paperback
        9 7 8 0 1 2 4 3 3 7 9 6 1
      • eBook
        9 7 8 0 3 2 3 1 6 1 3 7 4
      Methods of Enzymatic Analysis, Volume 2 reviews developments in the determination of enzyme activity, including advances in assay techniques. It discusses the principles on which measurements of enzymes are based, with each chapter including equations and each method consisting of the pipetting protocol. This volume is divided into four parts, each discussing a group of enzymes and their determination. Part I focuses on oxidoreductases, such as sorbitol dehydrogenase, lactate dehydrogenase, malate dehydrogenase, isocitrate dehydrogenase, 6-phosphogluconate dehydrogenase, xanthine oxidase, and glutamate dehydrogenase. Part II is concerned with transferases ranging from ornithine carbamoyltransferase and transamidinase to transketolase, transaldolase, UDP-glucuronyltransf... glutamate-pyruvate transaminase, and phosphotransferases. Part III discusses hydrolases including esterases, glycoside hydrolases, peptidases, and proteinases, whereas Part IV looks at lyases, isomerases, and ligases, such as fructose-1, 6-diphosphate aldolase, 1-phosphofructoaldol... glucosephosphate isomerase, and tetrahydrofolate formylase. This book is a valuable resource for biochemists as well as students and researchers working in the field of analytical biochemistry.

    • Biology of Fertilization V2

      • 1st Edition
      • December 2, 2012
      • Charles Metz
      • English
      • Paperback
        9 7 8 0 1 2 4 1 4 4 9 5 8
      • eBook
        9 7 8 0 3 2 3 1 4 8 1 4 6
      Biology of Fertilization, Volume 2: Biology of the Sperm is the second in a three-volume series that brings together various lines of research about reproduction in general and fertilization in particular. It is devoted to spermatogenesis, sperm physiology, and the initial interactions of sperm with egg components. The book is organized into three parts. Part I on spermatogenesis and sperm physiology includes studies on the evolution of the sperm cell; regulatory mechanisms, sperm antigen differentiation, and maturation of sperm in the reproductive tracts in mammals; physicochemical mechanisms of the acrosome filament extrusion process; and enzymes associated with sperm cell function. Part II deals with chemotaxis in microorganisms: bacteria and slime molds. Part III on gamete recognition and binding includes studies on identifying, isolating, and characterizing specific sperm and egg surface components involved in sperm-egg interaction; fertilization in the alga Fucus; fertilization in insects; and the role of lysins in fertilization.

    • Neoglycoconjugates

      • 1st Edition
      • December 2, 2012
      • Bozzano G Luisa
      • English
      • Paperback
        9 7 8 0 1 2 3 9 6 0 1 1 5
      • eBook
        9 7 8 0 3 2 3 1 3 8 8 3 3
      In recent decades, there has been an explosive growth in knowledge on the important biological roles of carbohydrates, especailly as specific information carriers. Neoglycoconjugates have been indispensable tools in these studies. This timely book, with both synthetic and application studies, will be of great value to researchers in a number of disciplines.

    • Refined Carbohydrate Foods And Disease

      • 1st Edition
      • December 2, 2012
      • D Burkitt
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 5 6 6 2
      • eBook
        9 7 8 0 3 2 3 1 5 3 6 8 3
      Refined Carbohydrate Foods and Disease: Some Implications of Dietary Fibre addresses the geographical distribution and historical emergence of the characteristically western diseases, which may be accounted for on a common dietary basis, particularly, on deficiency of dietary fiber. The book is divided into 10 parts, each with number of chapters focusing on relationship between disease and the environment; refined carbohydrate foods; various diseases of the large intestine; and other diseases that are associated with constipation, straining at stool, and refined carbohydrate foods. The book shows the role of refined carbohydrate foods as a significant cause of diseases, because it removes fiber, which has many unsuspected physiological functions. This reference is deemed to be useful to forge stronger links between epidemiologists and experimental workers.

    • Chemical and Biological Generation of Excited States

      • 1st Edition
      • December 2, 2012
      • Waldermar Adam
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 4 2 9 0
      • eBook
        9 7 8 0 3 2 3 1 5 2 3 0 3
      Chemical and Biological Generation of Excited States discusses major aspects of chemical and biological generation of electronic excitation. This book is organized into 11 chapters that focus on both chemi- and bioenergized processes. This book first discusses some of the fundamental aspects of the description of excited state behavior in condensed media. It then examines the field of gas-phase dioxetane chemiluminescence both by itself and in relation to solution-phase studies. The presented analysis is based on statistical mechanics and supported by a very simple limiting case calculation. Chapter 4 describes the state-of-the-art of how excitation yields are determined experimentally in chemienergized processes. This is followed by a discussion on activation parameters and stability trends, focusing on solution-phase data. Chapters 6 and 7 examine solution-phase chemiluminescence resulting from high-energy electron-transfer reaction, often involving aromatic radical ions, and the mechanism of excitation step. The next chapters cover the generation of electronic excited states in bioluminescence and the evaluation of luminescent oxidation mechanisms using oxygen tracers. The chapters also explain the formation of electronically excited products in dark biological processes and the mechanism of chemiexcitation as it relates to redox metabolism. Specific examples of biological oxygenation reactions yielding luminescence are also presented. Furthermore, this book discusses the concept and applicability of chemiluminigenic probing for the quantification and differentiation of oxygenation activities in mammalian phagocytes. The concluding chapter is devoted to the possible formation of singlet oxygen in various systems and processes that mimic singlet oxygen reactions. The book intends to attract young scientists as well as established research workers to broaden the horizons of this rapidly growing and potentially very important field.

    • Tissues and Body fluids

      • 1st Edition
      • December 2, 2012
      • Kurt Altman
      • English
      • Paperback
        9 7 8 0 1 2 4 3 1 3 4 7 7
      • Hardback
        9 7 8 0 1 2 0 5 4 5 0 2 5
      • eBook
        9 7 8 0 3 2 3 1 5 1 4 8 1
      Radiation Biochemistry, Volume II: Tissues and Body Fluids deals with the radiation biochemistry of mammalian organs and body fluids. Emphasis is placed on descriptions of overall biochemical changes in irradiated tissues and animals; on the dependency of these changes on cellular responses; and on the interactions among different organ systems. Consideration is also given to a practical application of radiation biochemistry to the problem of assessing the nature, tissue localization, and extent of radiation injury in man and animals. The book's nine chapters discuss the following: the general aspects of radiation biochemistry; bone marrow and red blood cells; lymphoid organs; gastrointestinal tract; the liver; radiation biochemistry of miscellaneous organs; radiation biochemistry of tumors; changes in the biochemistry of body fluids after irradiation; and hormones and systemic effects. This text will be useful to life scientists who are just embarking in the field of radiation biology. In particular, the discussions of the complications introduced by body changes secondary to radiation damage, such as partial starvation and changes in cell populations of a given tissue, should help prevent errors in interpretation that have been committed in the past.

    • Human Intestinal Microflora in Health and Disease

      • 1st Edition
      • December 2, 2012
      • David J. Hentges
      • English
      • Paperback
        9 7 8 0 1 2 3 9 5 9 8 9 8
      • eBook
        9 7 8 0 3 2 3 1 3 8 6 6 6
      Human Intestinal Microflora in Health and Disease deals with human indigenous intestinal flora, the vast assemblage of microorganisms that reside in the intestinal tract. It contains information on the composition of the flora, its development, metabolic activities, importance to the host, and the consequences of upsetting its ecology. The book is organized into four parts. Part I examines the composition and development of intestinal flora. Part II deals with the metabolic activities of intestinal microflora. These include studies on carbohydrate metabolism in the human colon; the compounds used as nitrogen sources by gastrointestinal tract bacteria; and metabolic transformations of xenobiotic compounds carried out by intestinal flora. Part III examines the importance of intestinal microflora, including its role in intestinal structure and function and in suppressing the growth of pathogens. Part IV discusses the factors that can disrupt the ecology of intestinal microflora, such as antimicrobial agents, pseudomembranous colitis, and dietary and environmental stress. The research presented in this book will be of interest to both basic scientists and physicians concerned with the effects of the intestinal flora on human life.

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