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    • Atlas of Human Tumor Cell Lines

      • 1st Edition
      • October 22, 2013
      • Robert K.M. Hay + 2 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 8 6 2 8
      Human tumor cells in culture are valuable for studying cancer causes and properties. This convenient reference provides useful information for cancer researchers on commonly used, established tumor cell lines of the major human organ systems.Atlas of Human Tumor Cell Lines includes data about morphological, metabolic, genetic, and growth characteristics of human tumor cells, with morphological characteristics presented in more than 250 photomicrographs. It also contains information for establishing and maintaining human tumor cell lines in culture, and each chapter covers future perspectives.

    • Probes and Membrane Function

      • 1st Edition
      • October 2, 2013
      • Britton Chance + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 7 1 3 8
      • Hardback
        9 7 8 0 1 2 1 6 7 8 0 1 2
      • eBook
        9 7 8 1 4 8 3 2 7 1 4 8 4
      Probes of Structure and Function of Macromolecules and Membranes, Volume I: Probes and Membrane Function discusses the developments in techniques for the measurement of rapid reactions and detection of enzymatic reactions in simple and complex systems. This book describes the application of the incisive techniques employed for the study of activity-related structural changes in enzymes to functionally related structural changes in membranes. The structural changes initiated in response to energy coupling and ion movements in mitochondria and axons are also elaborated. This publication covers the basic mechanisms by which structural changes can participate in energy coupling at the redox level of the hemoproteins that leads to the evaluation of the function of ubiquinone and cytochrome b in energy coupling. The function of factors that couple electron transport and energy conservation is likewise considered. This volume is a good reference for students and researchers conducting work on the structure and function of macromolecules and membranes.

    • Pharmacological Control of Heart and Circulation

      • 1st Edition
      • October 22, 2013
      • L. Tardos + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 3 6 8
      • eBook
        9 7 8 1 4 8 3 1 4 7 7 8 9
      Pharmacological Control of Heart and Circulation, Volume 1, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. Because the papers published in this volume cover diverse areas of the cardiovascular field, they had to be arranged into several smaller symposia. The common thread running through these symposia is their focus on some pathological condition of the heart and circulation as well as on their control by drugs. The first symposium is devoted to the pharmacological control of the adverse effects of coronary insufficiency including disturbances in rhythm. The second symposium is dedicated to cardiac hypertrophy; to the action of cardiac hypertrophy on the sensitivity of the heart to drugs; and to the changes in the biochemical parameters of the myocardium due to cardiomegaly. The third symposium deals with hypertension and its pharmacological control. Two separate symposia are devoted to new drugs, namely the fourth symposium to the cerebrovascular activity of Cavinton—a synthetic Vinca-derivative; and the fifth to a newly developed beta-adrenergic blocking agent, Tobanum, to its anti-arrhythmic action, its effect in myocardial ischemia and in hypertension. Finally, a short symposium on serotonin and serotonin antagonists, both of great importance in cardiovascular pharmacology, is included.

    • Modulation of Neurochemical Transmission

      • 1st Edition
      • October 22, 2013
      • E. S. Vizi
      • English
      • Paperback
        9 7 8 1 4 8 3 1 1 5 4 0 5
      • eBook
        9 7 8 1 4 8 3 1 4 7 8 2 6
      Modulation of Neurochemical Transmission, Volume II, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. It provides a summary of biochemical, electrophysiological... morphological, and pharmacological findings on the modulation of transmitter release. The 45 papers contained in this volume come from the most important laboratories and the contributors are among the world's foremost experts. Key topics discussed include the presynaptic inhibition of neurotransmitters; the properties of pre- and postsynaptic α receptors; histochemical mapping of dopamine neurons in the olfactory brain; neurophysiological aspects of dopaminergic supersensitivity; the role of ATPases in neurochemical transmission; and interaction between noradrenaline and vanadium on brain membrane ATPase. Also presented are papers on neurotransmission in the rat portal vein; the function of cysteine metabolism in rat brain; presynaptic dopamine receptors in sympathetic heart nerves of cats; LSD-induced behavioral effects in rats; and modulation of posttetanic response in the guinea-pig ileum.

    • The Rheumatic Diseases

      • 4th Edition
      • September 12, 2013
      • G. D. Kersley
      • English
      • Hardback
        9 7 8 1 4 8 3 2 3 3 0 7 9
      • Paperback
        9 7 8 1 4 8 3 2 5 6 3 2 0
      • eBook
        9 7 8 1 4 8 3 2 8 2 5 8 9
      The Rheumatic Diseases, Fourth Edition, provides a comprehensive discussion of the clinical features of rheumatic diseases. The book opens with discussions of stress, the steroids and ACTH, immunology and heredity. These are followed by separate on the incidence, diagnosis, treatment, and prognosis of systemic rheumatic diseases, rheumatoid disease, ankylosing spondylitis, osteo-arthritis and spondylosis, gout, subsidiary and pseudo rheumatoid syndromes, and non-articular rheumatism. This book makes no attempt to express every opinion nor to give references to research papers. It is not a book for the consultant in rheumatology. It is written for the final year student and General Practitioner, so that it can be read in sections or cover to cover. Every effort has been made to keep out unessential detail yet to give a balanced view on any problem likely to arise.

    • Cancer Immunotherapy

      • 2nd Edition
      • June 4, 2013
      • George C. Prendergast + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 2 9 6 8
      • eBook
        9 7 8 0 1 2 3 9 4 6 3 3 1
      There has been major growth in understanding immune suppression mechanisms and its relationship to cancer progression and therapy. This book highlights emerging new principles of immune suppression that drive cancer, and it offers radically new ideas about how therapy can be improved by attacking these principles. Following work that firmly establishes immune escape as an essential trait of cancer, recent studies have now defined specific mechanisms of tumor immune suppression. It also demonstrates how attacking tumors with molecular targeted therapeutics or traditional chemotherapeutic drugs can produce potent anti-tumor effects in preclinical models. This book provides basic, translational, and clinical cancer researchers with an indispensable overview of immune escape as a critical trait in cancer and how applying specific combinations of immunotherapy and chemotherapy to attack this trait may radically improve the treatment of advanced disease.

    • Control of Animal Cell Proliferation

      • 1st Edition
      • September 11, 2013
      • Alton L. Boynton + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 6 5 6 8
      • Hardback
        9 7 8 0 1 2 1 2 3 0 6 2 3
      • eBook
        9 7 8 1 4 8 3 2 7 6 6 6 3
      Control of Animal Cell Proliferation, Volume II discusses how animal cells become proliferatively autonomous, which results in malignant behavior. This book begins with trends and issues on membrane structure and teratocarcinoma research. The structure and function of several growth factors and their receptors such as thrombin, transferrin, glucocorticoid, and B and T cell factors are also discussed. This text likewise covers the mechanism of information transduction that includes intracellular pH and calcium. The aspects of genome organization and gene transcription are deliberated in the last chapters. This publication provides biologists and students with a coherent picture of cell proliferation.

    • Principles, Practices, and Positions in Neuropsychiatric Research

      • 1st Edition
      • October 22, 2013
      • Joseph V. Brady + 1 more
      • English
      • Hardback
        9 7 8 0 0 8 0 1 7 0 0 7 7
      • Paperback
        9 7 8 1 4 8 3 1 2 2 1 1 3
      • eBook
        9 7 8 1 4 8 3 1 5 4 5 3 4
      Principles, Practices and Positions in Neuropsychiatric Research contains the proceedings of a conference held in June 1970 at the Walter Reed Army Institute of Research, Washington, D.C., in tribute to Dr. David McKenzie Rioch upon his retirement as Director of the Neuropsychiatry Division of that institute. This book is composed of the original contributions presented at the conference, as well as several invited papers that could not be programmed at the meeting because of certain limitations. Topics covered in some papers focus on anatomy of the thalamus; glia-neuronal interaction; receptor characteristics and conduction velocities in bladder afferents; responses of photoreceptors; and specificity of responses of cells in the visual cortex. This text also discusses the channeling of responses elicited by hypothalamic stimulation; neurochemistry of reward and punishment; behavioral analysis of aphasia; and biology of sleep. The military psychiatry and changing systems of mental health care, as well as psychological issues in training for research in psychiatry are also addressed. The contributions in this book will serve to reflect the remarkable range of bio-social research interest and competence.

    • Selenium

      • 1st Edition
      • October 22, 2013
      • Irene Rosenfeld + 1 more
      • English
      • Hardback
        9 7 8 1 4 8 3 2 2 8 0 0 6
      • Paperback
        9 7 8 1 4 8 3 2 5 1 2 5 7
      • eBook
        9 7 8 1 4 8 3 2 7 5 9 0 1
      Selenium: Geobotany, Biochemistry, Toxicity, and Nutrition focuses on the properties, characteristics, reactions, applications, chemistry, and transformations of selenium. The book first offers information on the geological distribution of selenium, including the formation of seleniferous soils, chemical forms of selenium in soils, selenium in water, selenium on the sea floor and in sea water, and geobotany. The text then takes a look at selenium indicator in plants and accumulation of selenium by plants. Discussions focus on selenium accumulations in indicator plants; selenium accumulation in farm crops and native grasses; factors that influence selenium accumulation in plants; and identification of indicators by germination tests. The manuscript elaborates on selenium poisoning in animals and prevention and control of selenium poisoning. Acute selenium poisoning, chronic selenium poisoning by inorganic selenium, and recognition of poisonous range plants are also discussed. The text also examines selenium in nutrition and the chemistry of selenium. The publication is a valuable source of data for readers interested in the study of selenium.

    • Comparative Aspects of Haemolytic Disease of the Newborn

      • 1st Edition
      • September 11, 2013
      • G. Fulton Roberts
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 9 4 5 2
      • eBook
        9 7 8 1 4 8 3 1 9 5 2 6 1
      Comparative Aspects of Haemolytic Disease of the Newborn is intended as a short account of present-day views on hemolytic disease and immediately related matters. It provides a bibliography to guide the interested reader towards the published work in whichever field he seeks to study. This book is organized into nine chapters. The coverage of the chapters includes the comparative aspects and the experimental production of hemolytic disease in the newborn; historical aspects and serological considerations in hemolytic diseases in humans, horse, mule and pig. A chapter on the treatment of hemolytic diseases is also included. This book will be of interest to people interested in the care of young animals, whether in a medical or veterinary milieu.

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