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Elsevier

Books in Life sciences

  • 250 examens de laboratoire

    en pratique médicale courante
    • 13th Edition
    • René Caquet
    • French
    Les examens de laboratoire, parfois qualifiés d’examens «complémentaires» alors qu’ils sont indispensables, recherchent bactéries et virus, reconnaissent les cellules anormales, détectent les anticorps, évaluent le fonctionnement des organes, scrutent le milieu intérieur, examinent les gènes.Comment s’en passer ?Ce livre, élaboré par un clinicien, offre aux professionnels de santé un instrument de pratique quotidienne. Ouvrage de référence, il expose tout ce qu’il faut savoir pour prescrire des analyses médicales et interpréter les résultats.Les examens de laboratoire sont présentés sous forme de fiches, classées par ordre alphabétique, qui suivent un plan récurrent : mode et précautions de prélèvement, valeurs normales et cliniques (valeurs pathologiques), objectifs de l’examen et interprétation.Cet ouvrage décrit le raisonnement qui permet de déduire d’un résultat biologique les meilleures conclusions diagnostiques ou thérapeutiques possibles, en interprétant les résultats à la lumière de la clinique, de la littérature scientifique et des données de santé publique.Cette 13e édition est entièrement actualisée, notamment en fonction des publications récentes, des recommandations des sociétés savantes (VIH, allergies, auto-immunité...) et en accord avec la nomenclature de la Sécurité sociale.De nouveaux examens liés à l’actualité médicale (caryotype onco-hématologique, hématocrite, hépatite E…) sont ajoutés.L’ouvrage s’accorde volontairement à la pratique des généralistes, spécialistes et biologistes. Les examens plus rares (biologie moléculaire…) sont traités en accord avec la demande.

  • Inspiring Conversations with Women Professors

    The Many Routes to Career Success
    • 1st Edition
    • Anna Garry
    • English
    Inspiring Conversations with Women Professors: The Many Routes to Career Success provides stories behind the many paths to professorship taken by these featured women. It includes information on their diverse life stories and how they navigated the beginning, middle stages, and other parts of their careers, including unexpected paths, support and how they got hooked by science/their field. In addition, they discuss why they chose this career, the obstacles they encountered, and how they found a way forward. Each interview encapsulates the advice and practical solutions they give.

  • The Little Black Book of Neurology

    • 6th Edition
    • Osama O. Zaidat + 2 more
    • English
    Widely known and well-respected, The Little Black Book of Neurology has been a thorough yet portable reference in this complex field for more than 30 years, presenting definitions, classifications, and guidance on diagnosis and management for a wide range of neurological disorders. The 6th Edition offers updated and expanded coverage of neuropharmacology and neuroimaging – plus a new, more user-friendly, fast-access format that makes the book ideal for quick clinical consultation or as a refresher for the Boards.

  • Sherpath for Nutrition (Grodner Version)

    • 7th Edition
    • Elsevier Inc
    • English
    For today’s healthcare students, Sherpath is the learning tool that takes primary course content and gives you what you need to know now, in the time you have available, to achieve success tomorrow. It then adapts based on your personal interactions and responds by building on the topics and concepts where you need help. Sherpath brings content to life by integrating the core content to a digital environment and complementing it with videos, images, case studies, and micro simulations on a single platform. This version of Sherpath fully incorporates ebook content.

  • Les troubles du sommeil

    • 3rd Edition
    • Yves Dauvilliers
    • French
    La médecine du sommeil est une discipline récente et les manuels qui lui sont consacrés sont peu nombreux. Les troubles du sommeil et de l’éveil touchent pourtant une part importante de la population et ont de graves répercussions sur la santé physique et mentale, ainsi que sur la qualité de vie.La 3e édition de cet ouvrage de référence, entièrement mis à jour et agrémenté de questionnaires, d’échelles et d’un glossaire étendu :• fait le point sur le sommeil normal (aspects neurobiologiques et physiologiques chez l’enfant, l’adulte et le sujet âgé),• présente les différentes méthodes d’exploration,• propose une synthèse sur les multiples troubles (insomnie, hypersomnie, troubles du rythme circadien, parasomnie…),• établie le lien entre les troubles du sommeil et les spécialités médicales : neurologie, cardiologie, pneumologie, endocrinologie, pédiatrie, psychiatrie, ORL….Cet ouvrage s’adresse aux médecins généralistes et spécialistes. Ils y trouveront des réponses à leurs questions, ainsi que de nombreuses indications pour la prise en charge des patients et la prescription de traitements. Il s’adresse également à tous les professionnels de santé, chercheurs et étudiants désireux de s’ouvrir à un domaine encore peu enseigné dans les facultés et écoles.

  • Intracellular Signalling Proteins

    • 1st Edition
    • Volume 116
    • English
    Intracellular Signalling Proteins, Volume 116, presents an overview of the current developments in mechanisms of intracellular signaling and involvement of these mechanisms in the development of a number of disorders and diseases. Opportunities for targeting the intracellular signaling cascades for benefiting patients are also discussed, along with chapters that focus on Voices from the Dead: The Complex Language of Dead Cells, Nucleobindins and Encoded Peptides: From Cell Signalling to Physiology, Estrogen Receptor Signaling Mechanisms, Intracellular Signaling of the AMP-Activating Protein Kinase, the Relationship between Mitofusin 2 and Cancer, Molecular Signaling in Bone Cells: Regulation Cell Differentiation and Survival, and more.

  • Advances in Parasitology

    • 1st Edition
    • Volume 104
    • David Rollinson + 1 more
    • English
    Advances in Parasitology, Volume 104, the latest in a series first published in 1963, contains comprehensive reviews on all areas of interest in contemporary parasitology. The series includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy, and life history, which help to shape current thinking and applications. This new release includes sections on Leishmania Tropica, Extracellular Vesicles in Host-Parasite Interaction, Cathepsins and Vaccines for Fascioliosis, Echinococcosis Transmission on the Tibetan Plateau, A Review of Diagnostics for STH from a Public Health Perspective, and Zoonotic Transmission of Intestinal Parasites: Implications for Control and Elimination.

  • Evolution's Clinical Guidebook

    Translating Ancient Genes into Precision Medicine
    • 1st Edition
    • Jules J. Berman
    • English
    Evolution's Clinical Guidebook: Translating Ancient Genes into Precision Medicine demonstrates, through well-documented examples, how an understanding of the phylogenetic ancestry of humans allows us to make sense out of the flood of genetic data streaming from modern laboratories and how it can lead us to new ways to prevent, diagnose and treat diseases. Topics cover evolution and human genome, meiosis and other recombinants events, embryology, speciation, phylogeny, rare and common diseases, and the evolution of aging. This book is a valuable source for bioinformaticians and those in the biomedical field who need knowledge, down to gene level, to fully comprehend currently available data.

  • The Comorbidities of Epilepsy

    • 1st Edition
    • Marco Mula
    • English
    Epilepsy is one of most frequent neurological disorders affecting about 50 million people worldwide and 50% of them have at least another medical problem in comorbidity; sometimes this is a the cause of the epilepsy itself or it is due to shared neurobiological links between epilepsy and other medical conditions; other times it is a long-term consequence of the antiepileptic drug treatment. The Comorbidities of Epilepsy offers an up-to-date, comprehensive overview of all comorbidities of epilepsy (somatic, neurological and behavioral), by international authorities in the field of clinical epileptology, with an emphasis on epidemiology, pathophysiology, diagnosis and management. This book includes also a critical appraisal of the methodological aspects and limitations of current research on this field. Pharmacological issues in the management of comorbidities are discussed, providing information on drug dosages, side effects and interactions, in order to enable the reader to manage these patients safely. The Comorbidities of Epilepsy is aimed at all health professionals dealing with people with epilepsy including neurologists, epileptologists, psychiatrists, clinical psychologists, epilepsy specialist nurses and clinical researchers.

  • Cadmium Tolerance in Plants

    Agronomic, Molecular, Signaling, and Omic Approaches
    • 1st Edition
    • Mirza Hasanuzzaman + 1 more
    • English
    Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches presents research and latest developments on mechanisms of cadmium tolerance covering both lab and field conditions. This book contains important insights and options for minimizing Cd accumulation in plants and mitigating Cd toxicity. Topics covered include using various omics approaches to understanding plant responses to Cd, novel technologies for developing Cd tolerance and integrated breeding approaches to mitigate Cd stress in crops. Cadmium Toxicity and Tolerance in Plants: Agronomic, Genetic, Molecular and Omic Approaches is a valuable resource for both researchers and students working on cadmium pollution and plant responses as well as related fields of environmental contamination and toxicology.

  • Sex Determination in Vertebrates

    • 1st Edition
    • Volume 134
    • English
    Sex Determination, Volume 134, the latest release in the Current Topics in Developmental Biology series, contains current reviews in the field of vertebrate sex determination. It covers molecular pathways of sex determination in genetic and environmental species and encompasses both sex determination of somatic lineages and commitment of germ cells to male or female fate. Chapters in this new release cover, amongst other topics, Mapping the Sox9 Enhancer Elements, Epigenetic Regulation of Sex Determination, Evolution and Management of Sex Chromosomes, Regulation of Germ Cell Sex Identity in Medaka, Control of Sex Determination in Zebrafish, Sexually Dimorphic Germ Cell Identity in Mammals, and more.

  • Evaluation Technologies for Food Quality

    • 1st Edition
    • Jian Zhong + 1 more
    • English
    Evaluation Technologies for Food Quality summarizes food quality evaluation technologies, which include sensory evaluation techniques and chemical and physical analysis. In particular, the book introduces many novel micro and nano evaluation techniques, such as atomic force microscopy, scanning electron microscopy, and other nanomaterial-based methods. All topics cover basic principles, procedures, advantages, limitations, recent technology development, and application progress in different types of foods. This book is a valuable resource for scientists in the field of food science, engineering, and professionals in the food industry, as well as for undergraduate and postgraduate students studying food quality evaluation technology.

  • The Artificial Pancreas

    Current Situation and Future Directions
    • 1st Edition
    • Ricardo S. Sánchez-Peña + 1 more
    • English
    The Artificial Pancreas: Current Situation and Future Directions presents research on the top issues relating to the artificial pancreas (AP) and its application to diabetes. AP is a newer form of treatment to accurately and efficiently inject insulin, thereby significantly improving the patient’s quality of life. By connecting a continuous glucose monitor (CGM) to a continuous subcutaneous insulin infusion using a control algorithm, AP delivers and regulates the most accurate amount of insulin to maintain normal glycemic values. Featured chapters in this book are written by world leaders in AP research, thus providing readers with the latest studies and results.

  • Molecular Mechanisms of Dementia

    Biomarkers, Neurochemistry, and Therapy
    • 1st Edition
    • Akhlaq A. Farooqui
    • English
    Considerable progress has been made in neurochemical and therapeutic aspects of dementia research in recent years. Molecular and Therapeutic Aspects of Dementia presents readers with comprehensive and cutting-edge information on the neurochemical mechanisms of various types of dementias. It provides a clearly written and logically organized and comprehensive overview of molecular aspects of risk factors, symptoms, pathogenesis, biomarkers, and therapeutic strategies for various types of dementia. This book is written for the international audience of neurochemists, neuroscientists, neurologists, neuropharmacologists... and clinicians. The hope is that this discussion will not only integrate and consolidate knowledge in this field, but will jumpstart more studies on molecular mechanisms and therapeutic aspects of dementia. The comprehensive information in this monograph may not only help in early detection of various types of dementia and dementia linked neurological disorders, but also promote discovery of new drugs, which may block or delay the onset of dementia in elderly patients. Understanding the course of dementia is important not only for patients, caregivers, and health professionals, but also for health policy-makers, who have to plan for national resources needed in the management of an increasing number of dementia cases.　

  • Big Data Analytics for Intelligent Healthcare Management

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Big Data Analytics for Intelligent Healthcare Management covers both the theory and application of hardware platforms and architectures, the development of software methods, techniques and tools, applications and governance, and adoption strategies for the use of big data in healthcare and clinical research. The book provides the latest research findings on the use of big data analytics with statistical and machine learning techniques that analyze huge amounts of real-time healthcare data.

  • Mitochondria in Obesity and Type 2 Diabetes

    Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases
    • 1st Edition
    • Beatrice Morio + 2 more
    • English
    Mitochondria in Obesity and Type 2 Diabetes: Comprehensive Review on Mitochondrial Functioning and Involvement in Metabolic Diseases synthesizes discoveries from laboratories around the world, enhancing our understanding of the involvement of mitochondria in the etiology of diseases, such as obesity and type 2 diabetes. Chapters illustrate and provide an overview of key concepts on topics such as the role of mitochondria in adipose tissue, cancer, cardiovascular comorbidities, skeletal muscle, the liver, kidney, and more. This book is a must-have reference for students and educational teams in biology, physiology and medicine, and researchers.

  • Aging, Nutrition and Taste

    Nutrition, Food Science and Culinary Perspectives for Aging Tastefully
    • 1st Edition
    • Jacqueline B. Marcus
    • English
    Approximately 380 million people worldwide are 60 years of age or older. This number is predicted to triple to more than 1 billion by 2025. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully provides research, facts, theories, practical advice and recipes with full color photographs to feed the rapidly growing aging population healthfully. This book takes an integrated approach, utilizing nutrition, food science and the culinary arts. A significant number of aging adults may have taste and smell or chemosensory disorders and many may also be considered to be undernourished. While this can be partially attributed to the behavioral, physical and social changes that come with aging, the loss or decline in taste and smell may be at the root of other disorders. Aging adults may not know that these disorders exist nor what can be done to compensate. This text seeks to fill the knowledge gap. Aging, Nutrition and Taste: Nutrition, Food Science and Culinary Perspectives for Aging Tastefully examines aging from three perspectives: nutritional changes that affect health and well-being; food science applications that address age-specific chemosensory changes, compromised disease states and health, and culinary arts techniques that help make food more appealing to diminishing senses. Beyond scientific theory, readers will find practical tips and techniques, products, recipes, and menus to increase the desirability, consumption and gratification of healthy foods and beverages as people age.

  • Age Estimation

    A Multidisciplinary Approach
    • 1st Edition
    • Joe Adserias-Garriga
    • English
    Age Estimation: A Multidisciplinary Approach is the only reference in the field covering all techniques and methods involving age estimation from different perspectives in just one volume. The book provides comprehensive coverage of all aspects of age estimation: aging the living and the dead, human rights, and skeletal, dental, histological and biochemical techniques and methods available. Each chapter is written by internationally known expert contributors. Age Estimation: A Multidisciplinary Approach is a one of a kind resource for those involved in estimating the age of the living and the dead.

  • Sex Differences in Cardiovascular Physiology and Pathophysiology

    • 1st Edition
    • Babbette LaMarca + 1 more
    • English
    Sex Differences in Cardiovascular Physiology and Pathophysiology is a comprehensive look into the often overlooked and underappreciated fundamental sex differences between men and women and how those differences affect the cardiovascular system. It covers cardiovascular function, anatomy, cell signaling and the development of pathology. With contributions from world-renowned research investigators, this up-to-date reference compiles critical knowledge on cardiovascular sex differences, providing researchers and clinicians with a better understanding of the diagnosis, prevention and treatment of cardiovascular diseases in both men and women.

  • Paxinos and Franklin's the Mouse Brain in Stereotaxic Coordinates

    • 5th Edition
    • George Paxinos + 1 more
    • English
    Paxinos and Franklin’s The Mouse Brain in Stereotaxic Coordinates, Fifth Edition, emulates in design and accuracy Paxinos and Watson’s The Rat Brain in Stereotaxic Coordinates, the most cited publication in neuroscience.

  • Quorum Sensing

    Molecular Mechanism and Biotechnological Application
    • 1st Edition
    • Giuseppina Tommonaro
    • English
    Quorum sensing (QS) is a process of bacterial cooperative behaviour that has an effect on gene regulation. This cell-to-cell communication system involves the production of signalling molecules according to cell density and growth stage. Virulence, the ability to infest a habitat and cause disease, is also governed by such communication signals. Quorum Sensing: Molecular mechanism and biotechnological application collects, describes and summarizes the most interesting results obtained from experts working on QS mechanisms. It contributes to the understanding of the molecular basis that regulates this mechanism, and describes new findings in fields of application. This volume describes the QS mechanism from its molecular basis to medical applications such as antibiotic therapy and involvement of QS in pathologies. This reference also analyzes its potential use in biotechnological applications such as food packaging, drug delivery, and marine biofilm. The broad scope of this title will be of significant use to researchers across several fields with interest in QS, including to microbiologists, chemists, biochemists and ecologists.

  • Diagnostic Molecular Biology

    • 1st Edition
    • Chang-Hui Shen
    • English
    Diagnostic Molecular Biology describes the fundamentals of molecular biology in a clear, concise manner to aid in the comprehension of this complex subject. Each technique described in this book is explained within its conceptual framework to enhance understanding. The targeted approach covers the principles of molecular biology including the basic knowledge of nucleic acids, proteins, and genomes as well as the basic techniques and instrumentations that are often used in the field of molecular biology with detailed procedures and explanations. This book also covers the applications of the principles and techniques currently employed in the clinical laboratory.

  • Echinoderms Part B

    • 1st Edition
    • Volume 151
    • English
    Echinoderms, Volume 151, the latest release in the Methods in Cell Biology series, highlights advances in the field, with this update presenting chapters on Echinoderm Genome Databases, analysis of gene regulatory networks, using ATAC-seq and RNA-seq to increase resolution in GRN connectivity, multiplex cis-regulatory analysis, experimental approaches GRN/signal pathways, BACs, analysis of chromatin accessibility using ATAC-seq, analysis of sea urchin proteins /Click IT, CRISPR/Cas9-mediated genome editing in sea urchins, super-resolution and in toto imaging of echinoderm embryos, and methods for analysis of intracellular ion signals in sperm, eggs and embryos.

  • Clinical Genome Sequencing

    Psychological Considerations
    • 1st Edition
    • Aad Tibben + 1 more
    • English
    Clinical Genome Sequencing: Psychological Aspects thoroughly details key psychological factors to consider while implementing genome sequencing in clinical practice, taking into account the subtleties of genetic risk assessment, patient consent and best practices for sharing genomic findings. Chapter contributions from leading international researchers and practitioners cover topics ranging from the current state of genomic testing, to patient consent, patient responses to sequencing data, common uncertainties, direct-to-consumer genomics, the role of genome sequencing in precision medicine, genetic counseling and genome sequencing, genome sequencing in pediatrics, genome sequencing in prenatal testing, and ethical issues in genome sequencing. Applied clinical case studies support concept illustration, making this an invaluable, practical reference for this important and multifaceted topic area within genomic medicine.

  • Pharmaceutical Quality by Design

    Principles and Applications
    • 1st Edition
    • Sarwar Beg + 1 more
    • English
    Pharmaceutical Quality by Design: Principles and Applications discusses the Quality by Design (QbD) concept implemented by regulatory agencies to ensure the development of a consistent and high-quality pharmaceutical product that safely provides the maximum therapeutic benefit to patients. The book walks readers through the QbD framework by covering the fundamental principles of QbD, the current regulatory requirements, and the applications of QbD at various stages of pharmaceutical product development, including drug substance and excipient development, analytical development, formulation development, dissolution testing, manufacturing, stability studies, bioequivalence testing, risk and assessment, and clinical trials. Contributions from global leaders in QbD provide specific insight in its application in a diversity of pharmaceutical products, including nanopharmaceuticals, biopharmaceuticals, and vaccines. The inclusion of illustrations, practical examples, and case studies makes this book a useful reference guide to pharmaceutical scientists and researchers who are engaged in the formulation of various delivery systems and the analysis of pharmaceutical product development and drug manufacturing process.

  • The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle

    • 1st Edition
    • Eric Murillo-Rodriguez
    • English
    The Behavioral, Molecular, Pharmacological, and Clinical Basis of the Sleep-Wake Cycle provides the first comprehensive overview on the molecular methodologies used to evaluate sleep while also examining the cellular, biochemical, genetic, and therapeutic aspects of the sleep-wake cycle. There have been profound changes in the landscape of approaches to the study of sleep – mainly in the areas of molecular biology and molecular techniques. With this great focus on using multidisciplinary molecular methods, chapters address significant advances in the molecular mechanisms underlying sleep and the techniques researchers use to study this phenomenon. Written by world-leading experts in the area, this book is of great interest to researchers working in the sleep field and to anyone interested in one of the most mysterious phenomena in science – why we sleep and why we cannot survive without it.

  • Advances in Biomembranes and Lipid Self-Assembly

    • 1st Edition
    • Volume 29
    • Aleš Iglič︎ + 2 more
    • English
    Advances in Biomembranes and Lipid Self-Assembly, Volume 29, formerly titled Advances in Planar Lipid Bilayers and Liposomes, provides a global platform for the study of cell membranes, lipid model membranes, and lipid self-assemblies, from the micro- to the nanoscale. As planar lipid bilayers are widely studied due to their ubiquity in nature, this book presents research on their application in the formulation of biomimetic model membranes, and in the design of artificial dispersion of liposomes. Moreover, the book discusses how lipids self-assemble into a wide range of other structures, including micelles and the liquid crystalline hexagonal and cubic phases. Chapters in this volume present both original research and comprehensive reviews written by world leading experts and young researchers.

  • Ubiquitin-dependent Protein Degradation

    • 1st Edition
    • Volume 619
    • English
    Ubiquitination and Protein Stability - Part B, Volume 619, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapters written by an international board of authors. Topics of note include chapters on Assays of SUMO protease function in mammalian cells, In vitro analysis of proteasome-associate... USP14 activity for substrate degradation and deubiquitylation, Methods to study proteasome regulatory particle assembly, Native mass spectrometry approaches to study the proteasome, Single-molecule methods to study the ubiquitin-proteasome system, Assays for the function of ubiquitin in the mammalian endocytic pathway, and much more.

  • Progress in Molecular Biology and Translational Science

    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A
    • 1st Edition
    • Volume 162
    • English
    Glycans and Glycosaminoglycans as Clinical Biomarkers and Therapeutics - Part A, Volume 162 in the Progress in Molecular Biology and Translational Science series provides informative monographs on a variety of research topics related to Glycans and glycosaminoglycans as clinical biomarkers and therapeutics. Topics in this update include Glycan-based Biomarkers for Diagnosis of Cancers and Other Diseases: Past, Present and Future, Desialylation in Diseases and its Application in Diagnostic and Therapeutic Development, Proteoglycans as Miscommunication Biomarkers for Cancer Diagnosis, Fucosylation in Cancer Biology and Its Clinical Applications, Retrospective Analysis of Glycan-Related Biomarkers Based on Clinical Laboratory Data in Two Medical Centers, and many related topics.

  • Nucleic Acid Sensing and Immunity - PART B

    • 1st Edition
    • Volume 345
    • English
    Nucleic Acid Sensing and Immunity - PART B, Volume 345 gives a comprehensive overview of the nucleic acid machinery, from plants to mammalians, along with their regulation. Chapters in this updated volume include Nucleic acids sensing in allergic disorders, Nucleic acids sensing in autoimmune disorders, Nucleic acid sensing in inflammatory disorders, Viral nucleic acid sensing inflammasomes in intestinal host defense, Genome damage sensing leads to tissue homeostasis in Drosophila, Nucleic acids sensing in plants, Nucleic Acid sensing in invertebrates, amongst other topics.

  • Vertebrate Skeletal Development

    • 1st Edition
    • Volume 133
    • English
    Vertebrate Skeletal Development, Volume 133, the latest release in the Current Topics in Developmental Biology series, presents interesting chapters on a variety of topics, with this edition focusing on Craniofacial skeletal development, Regulatory mechanism of jawbone and tooth development, Development of the axial skeleton and intervertebral discs, Stem and progenitor cells in skeletal development, Origin, functioning and morphogenetic activity of limb synovial joint, ECM signaling in cartilage development and endochondral ossification, Sox genes in skeletal development, Wnt-Signaling in Skeletal Development, Gαs signaling in skeletal development and diseases, FGF signaling in skeletal development, Bone morphogenetic growth factors in bone development, and more.

  • Neuroscience of Nicotine

    Mechanisms and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Neuroscience of Nicotine: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of nicotine addiction and its effects on the brain. Offering thorough coverage of all aspects of nicotine research, treatment, policy and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of nicotine misuse. With an estimated one billion individuals worldwide classified as tobacco users—and tobacco use often being synonymous with nicotine addiction—nicotine is one of the world’s most common addictive substances, and a frequent comorbidity of misuse of other common addictive substances. Nicotine alters a variety of neurological processes, from molecular biology, to cognition, and quitting is exceedingly difficult because of the number of withdrawal symptoms that accompany the process.

  • Advances in Genetics

    • 1st Edition
    • Volume 103
    • English
    Advances in Genetics, Volume 103, provides the latest information on the rapidly evolving field of genetics, presenting new medical breakthroughs that are occurring as a result of advances in our knowledge of the topic. The book continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines, critically analyzing future directions.

  • Neuroscience of Alcohol

    Mechanisms and Treatment
    • 1st Edition
    • Victor R. Preedy
    • English
    Neuroscience of Alcohol: Mechanisms and Treatment presents the fundamental information necessary for a thorough understanding of the neurobiological underpinnings of alcohol addiction and its effects on the brain. Offering thorough coverage of all aspects of alcohol research, treatment and prevention, and containing contributions from internationally recognized experts, the book provides students, early-career researchers, and investigators at all levels with a fundamental introduction to all aspects of alcohol misuse. Alcohol is one of the world’s most common addictive substances, with about two billion individuals worldwide consuming it in one form or another and three million annual deaths that are associated with alcohol misuse. Alcohol alters a variety of neurological processes, from molecular biology, to cognition. Moreover, addiction to alcohol can lead to numerous other health concerns and damage virtually every organ system in the body, making diagnosis and treatment of individuals addicted to alcohol of critical importance.

  • Encyclopedia of Ocean Sciences

    • 3rd Edition
    • J. Kirk Cochran + 2 more
    • English
    The oceans cover 70% of the Earth’s surface, and are critical components of Earth’s climate system. This new edition of Encyclopedia of Ocean Sciences, Six Volume Set summarizes the breadth of knowledge about them, providing revised, up to date entries as well coverage of new topics in the field. New and expanded sections include microbial ecology, high latitude systems and the cryosphere, climate and climate change, hydrothermal and cold seep systems. The structure of the work provides a modern presentation of the field, reflecting the input and different perspective of chemical, physical and biological oceanography, the specialized area of expertise of each of the three Editors-in-Chief. In this framework maximum attention has been devoted to making this an organic and unified reference.

  • New and Future Developments in Microbial Biotechnology and Bioengineering

    Microbial Biotechnology in Agro-environmental Sustainability
    • 1st Edition
    • Jay Shankar Singh + 1 more
    • English
    New and Future Developments in Microbial Biotechnology and Bioengineering: Microbial Biotechnology in Agro-environmental Sustainability describes, in detail, the various roles of microbial resources in the management of crop diseases and how microbes can be used as a source of income for biomass and bioenergy production. In addition, the book covers microbial inoculants as bio-fertilizers to enhance crop productivity, along with degraded land restoration. Users will find the latest information in the field of microbial biotechnology and its further applications in bio-fertilizers, bio-pesticides, its generation as an alternative source of energy, restoration degraded and marginal lands, the mitigation of global warming gases, and more.

  • Amphibians of North Africa

    • 1st Edition
    • Daniel Escoriza + 1 more
    • English
    Amphibians of North Africa is a comprehensive compilation of available data on the amphibians and reptiles found in various ecosystems across North West Africa and parts of the Mediterranean region. It is essential to identifying and understanding the ecological role of regional herpetofauna and its conservational importance. It examines the biological origins and diversity of amphibians in North Africa, along with their diverse ecosystems, including deserts, grasslands and subtropical forests. The book features detailed descriptions of the adult and larvae stages of species, such as the North African fire salamander, the common painted frog, Brongersma's toad and the Mediterranean tree frog. This book is a vital resource for herpetology and ecology students and researchers, helping them identify, understand and conserve these amphibians and reptiles in their various habitats across the North African and Mediterranean regions.

  • Pharmaceutical Care in Digital Revolution

    Insights Towards Circular Innovation
    • 1st Edition
    • Claudia Rijcken + 1 more
    • English
    Pharmaceutical Care in Digital Revolution demonstrates how blending human and digital pharmaceutical care can establish optimal Apothecary Intelligence (AI). Organized into four parts, it examines digital health advances that will synergize the pharmaceutical care process and prepares stakeholders for a dynamic future, fueled with innovation. Beginning with the global picture on health care systems, patients’ expectations, and current pharmaceutical care practices, the book covers details of relevant digital technologies as well as compliance, ethical, educational, and cultural aspects to take successful steps towards digital pharmaceutical care. The text includes links to lectures and technology facts, tutorials on how to implement advances in your own working environment, and examples of stakeholders who are successful in building synergy between digital and pharma. Pharmaceutical Care in Digital Revolution is a practical resource to equip pharmaceutical care stakeholders, such as pharmacists, physicians, pharmacy technicians, and students as well as those in surrounding ecosystems like payers or regulators. It is a crucial reference to understand how technological innovation is changing the paradigm in which we provide current and future pharmaceutical care and how to keep it accessible, affordable, and sustainable.

  • Central Serous Chorioretinopathy

    • 1st Edition
    • Jay Chhablani
    • English
    Central Serous Chorioretinopathy discusses the mechanisms, pathogenesis and risk factors of CSCR, findings on various imaging modalities, available treatment options, and translational research into new treatment options for CSCR management. This comprehensive book is written for retina specialists and surgeons, researchers and clinical practitioners in sensory systems (vision), and ophthalmologists. Central Serous Chorioretinopathy (CSCR) is a common disorder across the world with a variable prognosis without any standard of care. Recently, advancements in imaging have led to a better understanding of the pathogenesis and mechanisms of this disease.

  • Progress in Medicinal Chemistry

    • 1st Edition
    • Volume 58
    • English
    Progress in Medicinal Chemistry, Volume 58, provides a review of eclectic developments in medicinal chemistry, with each chapter written by an international board of authors. Topics covered in this new release include Amyotrophic lateral sclerosis (ALS), Covalent-binding Drugs, Natural Product Drug Delivery – A Special Challenge?, and SMN2 gene splicing modifier, and more.

  • Highlighting Operational and Implementation Research for Control of Helminthiasis

    • 1st Edition
    • Volume 103
    • English
    Highlighting Operational and Implementation Research for Control of Helminthiasis, Volume 103 in the Advances in Parasitology series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history, all topics which help to shape current thinking and applications. This latest release includes chapters on Helminthiasis Epidemiology and Control: Scoring Successes and Meeting the Remaining Challenges, Worms, History and Swiss TPH, Mobile Microscopy, Combination Chemotherapy, DNDi Portfolio, Pediatric Praziquantel, lessons learned, and Community and Drug Distributor Perceptions and Experiences of Mass Drug Administration for the Elimination of Lymphatic Filariasis, amongst other topics.

  • Handbook of Sleep Disorders in Medical Conditions

    • 1st Edition
    • Josee Savard + 1 more
    • English
    Handbook of Sleep Disorders in Medical Conditions reviews the current knowledge on the nature and manifestations of sleep disorders associated with a variety of common medical conditions, including epilepsy, traumatic brain injury and dementia. It also provides clinical guidelines on how to assess and treat them with pharmacological and non-pharmacological interventions. Although the general principles of sleep medicine may be applied to some extent to patients with comorbid medical conditions, this book makes the case that an adaptive approach is warranted when considering the particularities of each condition. In addition, clinicians must also be cautious when prescribing sleep medications as some pharmacological agents are known to exacerbate symptoms associated with the medical condition, such as cognitive deficits (i.e. difficulties with memory and attention) in cancer patients experiencing chemo brain, or in persons with neurologic conditions (e.g. mild cognitive impairment, dementia, stroke, brain injury). A differential approach to evaluating and treating sleep is thus warranted.

  • Ecometabolomics

    Metabolic Fluxes versus Environmental Stoichiometry
    • 1st Edition
    • Sumira Jan + 1 more
    • English
    Ecometabolomics: Metabolic Fluxes versus Environmental Stoichiometry focuses on the interaction between plants—particularly plants that have vigorous secondary metabolites—and the environment. The book offers a comprehensive overview of the responses of the metabolome of organisms to biotic and abiotic environmental changes. It includes an introduction to metabolomics, summaries of metabolomic techniques and applications, studies of stress in plants, and insights into challenges. This is a must-have reference for plant biologists, plant biochemists, plant ecologists and phytochemists researching the interface between plants and the environment using metabolomics.

  • Platelets

    • 4th Edition
    • Alan D. Michelson + 3 more
    • English
    Platelets, Fourth Edition, integrates the entire field of platelet biology, pathophysiology, and clinical medicine with contributions from 142 world experts from 18 countries. This award-winning reference provides clear presentations by basic scientists on the cellular, molecular, and genetic mechanisms of platelets and the role of platelets in thrombosis, hemorrhage, inflammation, antimicrobial host defense, wound healing, angiogenesis and cancer. It also provides start-of-the-art presentations by hematologists, cardiologists, stroke physicians, blood bankers, pathologists and other clinicians on platelet function testing, disorders of platelet numbers and function, antiplatelet therapy and therapy to increase platelet numbers and/or function. Since the publication of the Third Edition of Platelets, there has been a rapid expansion of knowledge in both basic biology of platelets and the clinical approach to platelet-related diseases. This Fourth Edition of Platelets draws all this information into a single, comprehensive and authoritative resource.

  • Ubiquitin and Ubiquitin-like Protein Modifiers

    • 1st Edition
    • Volume 618
    • English
    Ubiquitination and Protein Stability - Part A Volume 618, the latest release in the Methods in Enzymology series, highlights new advances in the field, with this updated volume presenting interesting chapter written by an international board of authors. Topics of note in this new release include the Preparation of ubiquitinated nucleosomes with native and non-hydrolyzable linkages, Methods to measure ubiquitin chain length and linkage, Genetic approaches to study the yeast ubiquitin system, Enzymatic preparation of monoubiquitinated proteins, Methods to distinguish the function of ubiquitin in autophagy and the proteasome pathway, the Purification and characterization of enzyme activity of USPs, and much more.

  • Molecular Biology Techniques

    A Classroom Laboratory Manual
    • 4th Edition
    • Sue Carson + 3 more
    • English
    Molecular Biology Techniques: A Classroom Laboratory Manual, Fourth Edition is a must-have collection of methods and procedures on how to create a single, continuous, comprehensive project that teaches students basic molecular techniques. It is an indispensable tool for introducing advanced undergraduates and beginning graduate students to the techniques of recombinant DNA technology—or gene cloning and expression. The techniques used in basic research and biotechnology laboratories are covered in detail. Students will gain hands-on experience on subcloning a gene into an expression vector straight through to the purification of the recombinant protein.

  • Fermented Beverages

    Volume 5. The Science of Beverages
    • 1st Edition
    • Alexandru Grumezescu + 1 more
    • English
    Fermented Beverages, Volume Five, the latest release in The Science of Beverages series, examines emerging trends and applications of different fermented beverages, including alcoholic and non-alcoholic drinks. The book discusses processing techniques and microbiological methods for each classification, their potential health benefits, and overall functional properties. The book provides an excellent resource to broaden the reader’s understanding of different fermented beverages. It is ideal for research and development professionals who are working in the area of new products.

  • Pharmacoepidemiology and Pharmacovigilance

    • 1st Edition
    • Pascale Tubert-Bitter + 2 more
    • English
    Pharmacoepidemiology and Pharmacovigilance provides understanding of up-to-date statistical methods applied to drug safety assessment from observational data. Postmarketing drug safety raises challenging methodological issues.

  • Neural Stem Cells and Adult Neurogenesis

    • 1st Edition
    • Arie S. Mobley
    • English
    Neural Stem Cells and Adult Neurogenesis provides graduate students and neuroscientists with a basic understanding of what neural stem cells are and the cell types they produce. This early graduate level reference describes their physiology and potential for medicine and provides students with fundamental stem cell information. An overview of stem cell sources in the human body and a brief mention of relevant diseases provide context for the value of this knowledge. The book also includes chapters on induced pluripotent stem cells (iPSCs), the methods used to obtain them, and a review of the ethical challenges associated with stem cell research. For each region, the book provides a description of its neurogenic niche, cellular and molecular biology, and information on the neurons’ contribution to normal and diseased brain function. The level of information is appropriate for early graduate students, introducing technology and molecular biology in an accessible format.

  • Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy

    • 1st Edition
    • Volume 5
    • English
    Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy edited by Dr. Nagaraju, PhD., DSc. focuses on overriding the resistance from chemotherapeutic drugs with a broader range of treatment options. It particularly focuses on stroma, tumor microenvironment, stem cells, stellate cells, transcription factors, growth factors, and important signaling pathways. This volume discusses topics such as pancreatic cancer biology, current therapeutic options, EMT, chemotherapy resistance mechanisms, and genetic manipulations and natural products to enhance the sensitivity of pancreatic cancer to chemotherapy. Additionally, it discusses small targeted molecules and pancreatic cancer trials, and nanotechnology-based drug delivery.Breaking Tolerance to Pancreatic Cancer Unresponsiveness to Chemotherapy is a valuable source for researchers and advanced students in cancer and oncology as well as clinicians and medical students who are interested in learning more about ways to break pancreatic cancer resistance to chemotherapy.

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