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    • Honey Bee Pathology

      • 2nd Edition
      • October 22, 2013
      • Larissa Bailey + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 2 8 8 0 9 3
      Since the publication of the first edition of this book in 1982, investigation into the pathology of honey bees has progressed considerably. Furthermore, several different agents of disease, some newly discovered, have been causing increasing concern in recent years in many parts of the world.The book contains separate chapters on viruses, bacteria, fungi, protozoa, mites, nematode and insect parasites, non-infectious diseases, and the treatment of diseases. The contents are a thorough revision of the previous edition and incorporate much new information, especially with respect to viruses, bacteria, fungi, and mites. Specific organisms, such as the mite Varroa jacobsoni and the secondary diseases resulting from its presence, are considered in detail.Knowledge of the subject is central to well-managed beekeeping, an industry that, besides producing honey and wax for man, is increasingly valuable ecologically for pollinating wild as well as cultivated plants. Apart from its value for beekeeping and apicultural research, this book will also be of interest to ecologists, microbiologists, virologists, parasitologists, and general entomologists.

    • Essays in Toxicology

      • 1st Edition
      • October 22, 2013
      • Wayland J. Hayes
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 0 1 0
      • eBook
        9 7 8 1 4 8 3 2 1 6 4 4 7
      Essays in Toxicology, Volume 4 covers three essays on habituating drugs, on the kinetics of the active-site-directed irreversible inhibition, and the hidden effects of trace elements. The first essay examines certain dependence-producing drugs; the mechanism of tolerance to barbiturates by changes in drugs metabolism; the distribution of barbiturates to the central nervous system; and the urinary excretion of barbiturates. The formation of morphine from heroin and codeine, and the dealkylation to form normorphine and to reduce naloxone to another compound is also considered in the first essay. The second essay discusses the time-course of enzyme inhibition at single-inhibitor concentrations and the effect of various inhibitor concentrations on the rate constants governing inhibition. The third essay is about the recondite toxicity of trace elements, taking into consideration the effects of these trace elements on body weight, survival, and longevity, clues to mechanisms of toxicity, and the production of chronic diseases simulating human disorders. Toxicologists, oncologists, biochemists, and pharmacologists will find the book invaluable.

    • Advances in Dopamine Research

      • 1st Edition
      • October 22, 2013
      • M. Kohsaka + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 6 8 9 0
      • Hardback
        9 7 8 0 0 8 0 2 7 3 9 1 4
      • eBook
        9 7 8 1 4 8 3 1 5 9 3 1 7
      Advances in Dopamine Research documents the proceedings of a satellite symposium to the 8th International Congress of Pharmacology held in Okayama, Japan, July 1981. The importance of dopamine in brain function is reflected in this volume book by the chapters on the neurochemical, behavioral, neuroanatomical, and electrophysiological aspects of dopamine in the central nervous system. Dopamine receptor agonists and antagonists enjoy widespread use in the treatment of various brain disorders. A comprehensive account of research on the actions and mechanisms of action of drugs which affect central dopaminergic pathways is included in this volume. Also presented are accounts of the importance of dopamine and dopamine receptors in the periphery. It is hoped that this volume will be of interest to neuroscientists and pharmacologists, and indeed to all who are interested in clinical and scientific aspects of dopamine and other neurotransmitters.

    • Electrodeposition of Chromium from Chromic Acid Solutions

      • 1st Edition
      • October 22, 2013
      • George Dubpernell
      • English
      • Paperback
        9 7 8 1 4 8 3 1 2 7 6 8 2
      • Hardback
        9 7 8 0 0 8 0 2 1 9 2 5 7
      • eBook
        9 7 8 1 4 8 3 1 6 0 1 0 8
      Electrodeposition of Chromium from Chromic Acid Solutions focuses on the behavior of catalysts used in the electrodeposition of chromium from chromic acid solutions, particularly noting the characteristics, compositions, reactions, and applications of chromium. The book first offers information on the discovery of chromium by Nicolas-Louis Vauquelin, taking into consideration the experiments that he conducted to identify this metal. The manuscript then surveys the economic value of chromium deposition. Particularly given importance are the non-galling and wear resistant characteristics of chromium, enabling it to become a primary component in modern machines. The text describes the common forms of deposited chromium and catalyst balance. The differing electrochemical behaviors of cold chromium and bright chromium are discussed. The manuscript also presents information on empirical tests for catalyst concentration and bath balance and fluoride and complex fluoride catalyzed baths. The book is a vital source of data for readers wanting to explore electrodeposition of chromium from chromic acid solutions.

    • Drugs and Driving

      • 1st Edition
      • October 22, 2013
      • Herbert Moskowitz
      • English
      • Paperback
        9 7 8 1 4 8 3 1 7 2 0 3 3
      • eBook
        9 7 8 1 4 8 3 1 8 7 8 4 6
      Drugs and Driving is a compendium of papers from a symposium of the same title presented at the U.S. Transportation Research Board. This collection reviews the effects of five classes of drugs on driving (amphetamines, tranquilizers, barbiturates, narcotics, cannabis), the other studies being made on drugs and driving, as well as some countermeasure programs against drunk driving. The papers report that amphetamines can induce risky driving behavior, tranquilizers can increase traffic accident risks, barbiturates can degrade driving skills especially when the drug is combined with alcohol, while marijuana use can impair important driving skills. Another paper evaluates drug use and driving risk among high school students in Toronto: results show that the total effect of infrequent use of drugs on accidents is small compared to alcohol use. A study of out-patients in Finland notes that the combined used of alcohol and drugs tend to increase accident frequency. One paper refutes that Alcohol Safety Action Programs in the United States are ineffective. This collection can be helpful for sociologist, psychologists, psychiatrists, traffic safety officers, and heads of urban safety and traffic divisions.

    • The Future of Drug Discovery

      • 1st Edition
      • May 18, 2013
      • Tamas Bartfai + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 0 7 1 8 0 3
      • eBook
        9 7 8 0 1 2 4 0 9 5 1 9 9
      The Future of Drug Discovery: Who decides which diseases to treat? provides a timely and detailed look at the efforts of the pharmaceutical industry and how they relate, or should relate, to societal needs. The authors posit that as a result of increasing risk aversion and accelerated savings in research and development, the industry is not developing drugs for increasingly prevalent diseases, such as Alzheimer’s disease, untreatable pain, antibiotics and more. This book carefully exposes the gap between the medicines and therapies we need and the current business path. By analyzing the situation and discussing prospects for the next decade, the The Future of Drug Discovery is a timely book for all those who care about the development needs for drugs for disease.

    • Eutrophication of Deep Lakes

      • 1st Edition
      • October 22, 2013
      • S. H. Jenkins
      • English
      • Paperback
        9 7 8 0 0 8 0 2 6 0 2 4 2
      • eBook
        9 7 8 1 4 8 3 1 3 6 9 8 1
      Eutrophication of Deep Lakes focuses on research and experiments that are deemed valuable to mitigate the eutrophication of lakes. Containing the contributions of authors who have continuously conducted studies in this field, the book proceeds by pointing out how the loading concept can serve as a basis in the control of eutrophication. This discussion is seconded by discussions on the factors affecting the eutrophication of freshwaters in Norway. Particularly given attention in this book is the phosphorous content of small and large lakes. The relationship of pollution and eutrophication is also noted. The large inputs of nutrients into lakes is emphasized, and then the application of the US OECD eutrophication study results to deep lakes is discussed. The book also points to the stage of eutrophication of lakes in Norway, and particularly concerns the effect of eutrophication on living organisms in lakes. A review of the toxic substances that affect these organisms is also presented. The text is a valuable source of information for researchers and readers who are interested in studying how eutrophication affects the natural composition of lakes; how this process affects life in lakes; and the control measures and processes that need to be taken to control it.

    • Pharmacogenomics

      • 1st Edition
      • February 12, 2013
      • Yui-Wing Francis Lam + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 3 9 1 9 1 8 2
      • eBook
        9 7 8 0 1 2 3 9 8 3 0 3 9
      Pharmacogenomics: Challenges and Opportunities in Therapeutic Implementation includes discussions and viewpoints from the academic, regulatory, pharmaceutical, clinical, socio-ethical and economic perspectives. Each chapter presents an overview of the potential or opportunity within the areas discussed and also outlines foreseeable challenges and limitations in moving pharmacogenomics into drug development and direct therapeutic applications. This edited book contains review questions for a more in-depth analysis of the implications of pharmacogenomics and discussion points to generate ideas on best to move the field forward. Clinical pearls and case studies are used to illustrate real-life experiences and both successful and unsuccessful applications. Tables, figures, and annotations are included throughout the book to facilitate understanding and further reference.

    • Data Acquisition and Processing in Biology and Medicine

      • 1st Edition
      • October 22, 2013
      • Kurt Enslein + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 1 6 9 9 6 5
      • eBook
        9 7 8 1 4 8 3 1 8 5 7 7 4
      Data Acquisition and Processing in Biology and Medicine, Volume 4 deals with theories in data acquisition and processing as well as their implementation in biology and medicine. Topics covered range from computer-oriented study of human metabolism to automatic classification of chromosomes; retrieval and processing medical measurement data; data manipulation in investigational new drug applications; and methods of microglossary analysis. Comprised of 20 chapters, this volume begins with a description of the techniques, instrumentation, and analytical procedures for acquiring, storing, and retrieving psychophysiological data on more than 200 subjects. The discussion then turns to the use of computers to study human metabolism, for the reduction of ultracentrifuge data, and in objective content analysis of psychotherapy. Subsequent chapters explore mechanized image systems; cortical auditory response in humans; information processing by electric fishes; and fetal heart rate during cesarean section. This book will be useful for undergraduate students, educators, practitioners, and researchers in computing, biology, and medicine.

    • Physiology and Toxicology of Male Reproduction

      • 1st Edition
      • October 22, 2013
      • James C. Lamb + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 3 4 4 4 0 2
      • Paperback
        9 7 8 1 4 8 3 2 4 2 2 5 5
      • eBook
        9 7 8 1 4 8 3 2 7 2 0 7 8
      Physiology and Toxicology of Male Reproduction is a collection of papers that deals with general reproductive biology and specific aspects of reproductive toxicology, pertaining to the male sex. Some papers discuss testicular organization, reproductive toxicity testing systems, and germ-cell genetic toxicology. The use of in vitro systems by investigators to dissect the male reproductive toxicants can lead to a more scientific approach toward hazard assessment and the development of safer drugs and chemicals. Other papers explain the fundamental reproductive biology of the testis, the neuroendocrine system, the epididymis and accessory sex organs, and spermatozoal evaluation. Toxicological aspects cover the toxicological evaluation of the complete reproductive system, testicular morphology, sperm assessment, and germ-cell mutagenesis. One paper describes alternative methods in toxicology—by using new in vitro systems that should reduce or eliminate the need for tests conducted on animals. In vitro methodology embraces other systems such as from subcellular fractions to isolated intact organs. In relation to target-organ toxicity, the researcher can focus using primary cell cultures. This collection will prove helpful to toxicologists, graduate students and researchers in biology, particularly in male reproductive toxicology and fertility testing.

Related subjects

Agricultural and biological sciences

Drug discovery

Immunology

Microbiology and virology

Neuroscience

Pharmaceutical sciences

Pharmacology

Toxicology