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Elsevier

Books in Life sciences

  • The Role of Products of the Histocompatibility Gene Complex in Immune Responses

    • 1st Edition
    • David H. Katz + 1 more
    • English
    The Role of Products of the Histocompatibility Gene Complex in Immune Responses documents the proceedings of a conference held on 3-7 November 1975, which brought together an international group of scientists spanning three independent disciplines—genetics and immunogenetics, molecular biochemistry, and immunobiology—with clinical medicine overlapping these disciplines. This volume contains 42 papers organized according to the eight sessions held at the conference. The papers in Session I examined the genetics of the major histocompatibility complex. Session II presented studies on the biology of mixed lymphocyte interactions and cell-mediated cytotoxicity reactions. Session III discussed immune response gene systems while Session IV dealt with the genetic control of cell interactions. The papers in Session V covered idiotypic determinants on T cell receptors. Session VI investigated the properties of histocompatibility gene products involved in regulation of immune responses. Session VII focused on the biochemistry and immunocytology of cell surface products of the major histocompatibility complex. Finally, Session VIII discussed interrelationships between products of the major histocompatibility complex and their relevance to disease.

  • Immunobiology of Transfer Factor

    • 1st Edition
    • Charles H. Kirkpatrick + 2 more
    • English
    Immunobiology of Transfer Factor compiles research papers presented at the Fourth International Transfer Factor Workshop, held at the Given Institute of Pathobiology in Aspen, Colorado, on October 3-6, 1982. This book focuses on the immunologic effects of transfer factor, which are supported by in vitro and in vivo experiments that indicate immunologically specific interactions between transfer factor and antigens. The topics include the selective removal of transfer factor activity with antigen, antigen-specific suppressor factor in human leukocyte dialysates, and specific suppressor dialysates from mice. The kinetics of immune response and production of transfer factor in bovine, dialyzable leukocyte extracts in pulmonary diseases, and mechanisms of action of human transfer factor are also elaborated. This compilation is suitable for microbiologists, immunologists, and specialists researching on transfer factor.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 19
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 19 is a seven-chapter text that covers the physical and biological aspects of lipid metabolism. The first chapter deals with the interactions between circulating lipids and lipid proteins and the arterial tissue matrix. The subsequent chapter discusses the apolipoprotein C metabolism, the roles of lecithin-cholesterol acyltransferase and cholesterol ester transfer protein in intravascular cholesterol transport. Other chapters explore the significance of bile acid biosynthesis for cholesterol homeostasis, the metabolism of phosphatidylserine, and gas chromatographic and mass spectrometry analysis of prostanoids. The last chapter considers the role of dietary fiber in health and disease. This book is of great value to lipid and enzyme chemists, biochemists, and researchers.

  • Pheromone Biochemistry

    • 1st Edition
    • Glenn D. Prestwich + 1 more
    • English
    Pheromone Biochemistry covers chapters on Lepidoptera, ticks, flies, beetles, and even vertebrate olfactory biochemistry. The book discusses pheromone production and its regulation in female insects; as well as reception, perception, and degradation of pheromones by male insects. The text then describes the pheromone biosynthesis and its regulation and the reception and catabolism of pheromones. Researchers in the areas of chemistry, biochemistry, entomology, neurobiology, molecular biology, enzymology, morphology, behavior, and ecology will find the book useful.

  • In Vitro Methods in Cell-Mediated Immunity

    • 1st Edition
    • Barry R. Bloom + 1 more
    • English
    In Vitro Methods in Cell-Mediated Immunity focuses on methods for approaching cell-mediated immune responses in vitro. This book provides, in simplified in vitro systems, a basis for understanding the mechanism of the in vivo response and discusses useful and reliable in vitro tests for cell-mediated immune responses in humans, where in vivo testing is often not possible. The topics discussed include factors and activities produced in vitro by lymphocytes; biological implications of in vitro phenomena; and requirements and prospects for improved methodology. The leucocyte migration technique for in vitro detection of cellular hypersensitivity in man; proliferation of human blood lymphocytes stimulated by antigen in vitro; and virus plaque assay for antigen-sensitive are also elaborated in this text. This publication is a good reference for microbiologist and immunologists, including medical students researching on in vitro models for cell-mediated immune reactions.

  • Advances in Lipid Research

    • 1st Edition
    • Volume 22
    • Rodolfo Paoletti + 1 more
    • English
    Advances in Lipid Research, Volume 22 provides information pertinent to the fundamental aspects of lipid research. This book covers a variety of topics, including lipid secretion, lipids in platelet function, lipid transfer proteins, serum cholesterol, and cholesterol metabolism. Organized into five chapters, this volume begins with an overview of the lipid secretion of the meibomian glands, with emphasis on its chemical composition and physical properties. This text then explains the influence of lipids in platelet function and considers the metabolism of arachidonic acid in disease states, such as diabetes, nephrosis, and atherosclerosis. Other chapters examine the manner in which dietary cholesterol contributes to regulation of cholesterol metabolism. This book discusses as well the identification, isolation, and metabolism of sterol carrier proteins and lipid transfer proteins. The final chapter deals with the underlying problems that militate against a simple dose–response relationship. This book is a valuable resource for biologist, biochemists, and clinicians.

  • Molecules, Cells, and Parasites in Immunology

    • 1st Edition
    • Carlos Larralde + 2 more
    • English
    Molecules, Cells, and Parasites in Immunology contains the proceedings of a symposium on immunology held in Mexico City in the fall of 1979 under the auspices of the National University of Mexico (UNAM). This volume brings together prominent foreign scientists and Mexican investigators to discuss the areas of immunology that being developed at UNAM. Either in the form of reviews or of original presentations, the various authors proffer observations and ideas that generally relate to the regulation of the immune response at the molecular and cellular levels. The topic of Molecules encompasses the effect of molecular aggregation upon the triggering of physiological events, cooperative binding, and the expression of immunoglobulins during the lymphocyte differentiation process. Under the heading of Cells, there are contributions dealing with the physiological and pathological roles of interiorized antibodies; the mechanisms of antigen recognition by T cells; and the synthesis of membrane proteins by myeloma cells which somehow protect them from killer T cells. The section on Parasites includes some unique contributions on the immunology of human and animal cysticercosis and amebiasis, complemented by a general discussion of host-parasite relationships.

  • Blood and Tissue Antigens

    International Symposium on Blood and Tissue Antigens Held at the University of Michigan Medical Center, September 17-19, 1969
    • 1st Edition
    • David Aminoff
    • English
    Blood and Tissue Antigens documents the proceedings of the International Symposium on Blood and Tissue Antigens held in Ann Arbor, Michigan on September 17-19, 1969. This book focuses on the immunogenetic and biochemical aspects of the blood and tissue antigens. The topics discussed include the genetics of blood groups; blood groups and serum phosphatase; immunogenetics of the mouse H-2 system; and glycolipids as membrane antigens. The carbohydrate composition of epithelial mucins; glycolipids in SV40 and polyoma virus transformed mouse cell lines; and metabolic variations of serum proteins and enzymes are also elaborated. This text likewise covers the action of glycosidases on erythrocytes; blood group specific oligosaccharides in urine; biosynthesis of submaxillary mucins; and genes, glycosyltransferases... and blood types. This publication is a good source for students and individuals researching on blood and tissue antigens.

  • Current Topics in Bioenergetics

    Volume 11
    • 1st Edition
    • D. Rao Sanadi
    • English
    Current Topics in Bioenergetics, Volume 11 provides information pertinent to the ATP utilizing or synthesizing parts of the major bioenergetics reactions of cells. This book discusses the individual proteins comprising each of the energy-transducing ATPases and their organization into a functional structure. Organized into six chapters, this volume begins with an overview of the role of ATPases in the production and utilization of the H+ gradient from a genetic and biochemical viewpoint. This text then examines the ATPase associated with bacterial membranes, which is known to have an analogous function and a similar structure to that found in membranes of chloroplasts and mitochondria. Other chapters consider the composition and the biogenesis of chromaffin granules. This book discusses as well the models for the mode of action of peptide molecules. The final chapter deals with the various forms of energy transduction. This book is a valuable resource for biologists, physiologists, and pharmacologists.

  • Antigens, Lymphoid Cells and the Immune Response

    • 1st Edition
    • G. J. V. Nossal + 1 more
    • F. J. Dixon + 1 more
    • English
    Antigens, Lymphoid Cells, and the Immune Response deals with the nature and properties of antigens and with the functional anatomy and cell physiology of the mammalian lymphoid system which responds to antigens. The book discusses the central questions in cellular immunology; the antigens and the afferent limb of the immune response; and antibodies and the afferent limb of the immune response. The text also describes the organ distribution of antigens; the functional anatomy of the lymphoid system; and the behavior patterns of lymphoid cells. The microscopic and electron microscopic distribution of antigen in lymphoid organs; the interaction of antigens with cells of the reticuloendothelial system; and the interaction of antigen with lymphoid cells are also considered. The book further tackles the role of antigen in immunological tolerance; antibody production and tolerance dissociated; and antigen and lymphoid cells.

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