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2nd Edition - July 10, 2013
Authors: David P. Clark, Nanette J. Pazdernik
Molecular Biology, Second Edition, introduces the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This new edition… Read more
Immediately download your ebook while waiting for your print delivery. No promo code is needed.
Molecular Biology, Second Edition, introduces the basic concepts of molecular biology while incorporating primary literature from today’s leading researchers. This new edition reflects the massive surge in our understanding of the molecular foundations of genetics, thanks to major scientific revolutions in genetics and computer technology. It explains how living organisms function at a molecular level and how DNA, RNA, and proteins interact to provide the cell with genetic information.
This volume goes far beyond the flowing text, annotation, and hyperlinking available in most ebooks. Unique features include interactive quizzes for enhanced student understanding and self-testing; narrated animations to clarify complex content; and study guides equipped with 62 full-text Cell Press journal articles, all in one downloadable package. Also new to this second edition are updated chapters on genomics and systems biology, proteomics, bacterial genetics, and molecular evolution and RNA. A fully revised art completes the updates made in this ebook.
This book will be of interest to undergraduate students taking a course in Molecular Biology, as well as upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture.
Undergraduate students taking a course in Molecular Biology; upper-level students studying Cell Biology, Microbiology, Genetics, Biology, Pharmacology, Biotechnology, Biochemistry and Agriculture
Unit 1: Basic Chemical and Biological Principles
Ch1 Cells and Organisms
Ch2 Basic Genetics
Ch3 DNA, RNA, and Protein
Ch4 Genes, Genomes, and DNA
Ch5 Manipulation of Nucleic Acids
Unit 2: The Genome
Ch6 Polymerase Chain Reaction
Ch7 Cloning Genes for Analysis
Ch8 DNA Sequencing
Ch9 Genomics & Systems Biology
Unit 3: The Central Dogma of Molecular Biology
Ch10 Cell Division and DNA Replication
Ch11 Transcription of Genes
Ch12 Processing of RNA
Ch13 Protein Synthesis
Ch14 Protein Structure & Function
Ch15 Proteomics: Global Analysis of Proteins
Unit 4: Regulating Gene Expression
Ch16 Regulation of Transcription in Prokaryotes
Ch17 Regulation of Transcription in Eukaryotes
Ch18 Regulation at RNA Level
Ch19 Analysis of Gene Expression (Transcriptome)
Unit 5: Subcellular Life Forms
Ch20 Plasmids
Ch21 Viruses
Ch22 Mobile DNA
Unit 6: Changing the DNA Blueprint
Ch23 Mutations and Repair
Ch24 Recombination
Ch25 Bacterial Genetics
Ch26 Molecular Evolution
DC
David P. Clark did his graduate work on bacterial antibiotic resistance to earn his Ph.D. from Bristol University, in the West of England. During this time, he visited the British Government's biological warfare facility at Porton Down and was privileged to walk inside the (disused) Black Death fermenter. He later crossed the Atlantic to work as a postdoctoral researcher at Yale University and then the University of Illinois. Dr Clark recently retired from teaching Molecular Biology and Bacterial Physiology at Southern Illinois University which he joined in 1981. His research into the Regulation of Alcohol Fermentation in E. coli was funded by the U.S. Department of Energy, from 1982 till 2007. From 1984-1991 he was also involved in a project to use genetically altered bacteria to remove contaminating sulfur from coal, jointly funded by the US Department of Energy and the Illinois Coal Development Board. In 1991 he received a Royal Society Guest Research Fellowship to work at Sheffield University, England while on sabbatical leave. He has supervised 11 master’s and 7 PhD students and published approximately 70 articles in scientific journals. He has written or co-authored several textbooks, including Molecular Biology and Biotechnology, both published by Elsevier.
NP
Nanette J. Pazdernik has devoted her career to the understanding of molecular biology and biotechnology, and then disseminating that knowledge by writing and teaching. She is a co-author of Biotechnology, 2nd edition and Molecular Biology, 3rd edition, with Dr. David P. Clark and Dr. Michelle McGehee. Both the second and third edition of Molecular Biology won a Texty award from the Textbook and Academic Authors Association. She has taught courses in General Biology, Genetics, as well as Anatomy and Physiology at Southwestern Illinois College, McKendree University, and Harris-Stowe University. She received her BA in Biology from Lawrence University in Appleton, Wisconsin, and her PhD in Molecular, Cellular, Developmental Biology and Genetics from the University of Minnesota. Her doctoral thesis studied protein structure-function relationships. Following her degrees, she investigated the signal transduction pathways that control apoptosis and immunity at Indiana University School of Medicine. In a second post-doctoral position, she studied the various molecules that maintain the stem cell niche in the Department of Genetics at Washington University School of Medicine in St. Louis, MO. Currently, Dr. Pazdernik works in the biotech industry as a scientific writer.