Life sciences print books and ebooks | Elsevier

Brain Metastases from Primary Tumors Volume 1

1st Edition
April 3, 2014
M. A. Hayat
English
Hardback
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eBook
9 7 8 0 1 2 8 0 1 0 9 5 2

With an annual rate of more than 12 million global diagnoses and 7.6 million deaths, the societal and economic burden of cancer cannot be overstated. Brain metastases are the most common malignant tumors of the central nervous system, yet their incidence appears to be increasing in spite of the advancement of cancer therapies. While much is known about primary cancers (including primary brain tumors), less work has been done to uncover the roots of metastatic disease. Brain Metastases from Primary Tumors Volume 1 fills that gap, serving as the first reference to focus primarily on the link between primary cancers and brain metastases. This link is explored for the most common cancer types – lung, breast, and melanoma. Additionally, biological background as well as therapy for CNS metastases is addressed. Age and gender related trends are also discussed, as is the use of biomarkers for early detection.

Biofilms in Infection Prevention and Control

1st Edition
January 30, 2014
Steven L. Percival + 3 more
English
Hardback
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eBook
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Biofilms in Infection and Disease Control: A Healthcare Handbook outlines the scientific evidence and rationale for the prevention of infection, the role biofilms play in infection control, and the issues concerning their resistance to antimicrobials. This book provides practical guidance for healthcare and infection control professionals, as well as students, for preventing and controlling infection. Biofilms are the most common mode of bacterial growth in nature. Highly resistant to antibiotics and antimicrobials, biofilms are the source of more than 65 percent of health care associated infections (HCAI), which, according to the WHO, affect 1.4 million people annually. Biofilms are involved in 80 percent of all microbial infections in the body, including those associated with medical devices such as catheters, endotracheal tubes, joint prostheses, and heart valves. Biofilms are also the principle causes of infections of the middle-ear, dental caries, gingivitis, prostatitis and cystic fibrosis. Importantly, biofilms also significantly delay wound healing and reduce antimicrobial efficiency in at-risk or infected skin wounds.

Aging

1st Edition
March 5, 2014
Victor R Preedy
English
Paperback
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Hardback
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eBook
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Aging: Oxidative Stress and Dietary Antioxidants bridges the trans-disciplinary divide and covers in a single volume the science of oxidative stress in aging and the potentially therapeutic use of natural antioxidants in the diet or food matrix. The processes within the science of oxidative stress are described in concert with other processes, such as apoptosis, cell signaling, and receptor mediated responses. This approach recognizes that diseases are often multifactorial, and oxidative stress is a single component of this. Gerontologists, geriatricians, nutritionists, and dieticians are separated by divergent skills and professional disciplines that need to be bridged in order to advance preventative as well as treatment strategies. While gerontologists and geriatricians may study the underlying processes of aging, they are less likely to be conversant in the science of nutrition and dietetics. On the other hand, nutritionists and dietitians are less conversant with the detailed clinical background and science of gerontology. This book addresses this gap and brings each of these disciplines to bear on the processes inherent in the oxidative stress of aging.

Quantitative MRI of the Spinal Cord

1st Edition
January 16, 2014
Julien Cohen-Adad + 1 more
English
Hardback
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eBook
9 7 8 0 1 2 3 9 7 2 8 2 8

Quantitative MRI of the Spinal Cord is the first book focused on quantitative MRI techniques with specific application to the human spinal cord. This work includes coverage of diffusion-weighted imaging, magnetization transfer imaging, relaxometry, functional MRI, and spectroscopy. Although these methods have been successfully used in the brain for the past 20 years, their application in the spinal cord remains problematic due to important acquisition challenges (such as small cross-sectional size, motion, and susceptibility artifacts). To date, there is no consensus on how to apply these techniques; this book reviews and synthesizes state-of-the-art methods so users can successfully apply them to the spinal cord. Quantitative MRI of the Spinal Cord introduces the theory behind each quantitative technique, reviews each theory’s applications in the human spinal cord and describes its pros and cons, and suggests a simple protocol for applying each quantitative technique to the spinal cord.

Biochemistry LabFax

1st Edition
June 28, 2014
English
Paperback
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eBook
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LABFAX volumes are purpose-designed data reference books for practising scientists. Each book presents key information for a major subject in one place and so saves hours of searching. It does not simply collect together data which are already available in catalogues since these are often incomplete and can contain conflicting information. Rather, the authors and editors of each LABFAX volume have searched the original literature for the accurate data which they know the specialist needs.Biochemistry LabFax is a detailed compendium of essential information - on radioisotopes, enzymes, proteins, nucleic acids, lipids, plus data on selected techniques such as chromatography, electrophoresis, etc. - needed on an almost daily basis by researchers in any area of biochemistry. In addition, the book acts as a gateway to other sources for information more specific than can be covered in a volume of this size.

Natural Resource Administration

1st Edition
January 10, 2014
Donald W. Sparling
English
Paperback
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eBook
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Natural Resource and Wildlife Administration presents a clear perspective on natural resource administration in North America, how it developed, how it is currently structured, and where it might be heading. Intertwined areas of natural resources, including wildlife administration, fisheries, forestry, and other competitive land uses, are heavily discussed. The book covers the history of natural resource management in Europe and North America, proceeding to environmental law; agencies involved in wildlife and natural resource management; and the human dimensions of public relations and economic concerns. Natural Resource and Wildlife Administration provides solid background on the history of natural resource conservation, critical laws protecting resources, and the nature of agencies. The interconnectedness among natural resources makes this a useful text for disciplines such as wildlife, fisheries, and forestry.

Pheromone Biochemistry

1st Edition
June 28, 2014
Glenn D. Prestwich + 1 more
English
Paperback
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eBook
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Pheromone Biochemistry covers chapters on Lepidoptera, ticks, flies, beetles, and even vertebrate olfactory biochemistry. The book discusses pheromone production and its regulation in female insects; as well as reception, perception, and degradation of pheromones by male insects. The text then describes the pheromone biosynthesis and its regulation and the reception and catabolism of pheromones. Researchers in the areas of chemistry, biochemistry, entomology, neurobiology, molecular biology, enzymology, morphology, behavior, and ecology will find the book useful.

Class 1 Devices

1st Edition
November 24, 2014
Peter J. Ogrodnik
English
Paperback
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eBook
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The Case Studies in Medical Devices Design series consists of practical, applied case studies relating to medical device design in industry. These titles complement Ogrodnik’s Medical Device Design and will assist engineers with applying the theory in practice. The case studies presented directly relate to Class I, Class IIa, Class IIb and Class III medical devices. Designers and companies who wish to extend their knowledge in a specific discipline related to their respective class of operation will find any or all of these titles a great addition to their library. Class 1 Devices is a companion text to Medical Devices Design: Innovation from Concept to Market. The intention of this book, and its sister books in the series, is to support the concepts presented in Medical Devices Design through case studies. In the context of this book the case studies consider Class I (EU) and 510(k) exempt (FDA) . This book covers classifications, the conceptual and embodiment phase, plus design from idea to PDS.

Metabolic Conjugation and Metabolic Hydrolysis

1st Edition
May 10, 2014
William H. Fishman
English
Paperback
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eBook
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Metabolic Conjugation and Metabolic Hydrolysis, Volume I is a comprehensive account of the main conjugation mechanisms and hydrolytic reactions. Topics covered range from the metabolic conjugates of steroids and N-hydroxy compounds to the effects of conjugated steroids on enzymes. The glucuronic acid pathway is also discussed, along with sulfoconjugation and sulfohydrolysis. Comprised of eight chapters, this volume first looks at the history of conjugation mechanisms before proceeding to developments in metabolic conjugations. The isolation, recognition, enzymic formation and hydrolysis, and the possible significance of steroid N-acetylglucosaminid... and glucosides are considered. The book also examines the mechanisms involved in the enzymic formation of N-hydroxy compounds; the pathways by which N-hydroxy compounds may be further metabolized in vivo; and the chemical properties of conjugates of N-hydroxy compounds, particularly as these properties are related to the generation of reactive cations or free radicals in vivo. The possible role of conjugates of N-hydroxy compounds in the mechanism of carcinogenesis by aromatic amines and their N-acyl derivatives is also analyzed. Finally, glycoprotein and mucopolysaccharide hydrolysis and the role of hydrolases in cellular death are described. This monograph will be a useful resource for biologists, biochemists, physiologists, and pharmacologists.

Advances in Lipid Research

1st Edition
Volume 11
June 28, 2014
Rodolfo Paoletti + 1 more
English
eBook
9 7 8 1 4 8 3 2 1 5 3 3 4

Advances in Lipid Research, Volume 11 is a seven-chapter text that discusses a wide range of topics in the field, including steroid metabolism, phytosterols, and fatty acid transport. The first chapter reviews the metabolic role of lecithin: cholesterol acyltransferase. The next chapter deals with the simple means of separation and quantitation of serum lipoproteins. This chapter describes the variations of the reaction involving lipoproteins, divalent cations, and polyanionic substances, both organic and inorganic. Other chapters discuss the fatty acid metabolism by brain tissue, the concept of the blood-brain barrier and its role in fatty acid uptake, as well as the many alterations in bile acid structure due to their interaction with the intestinal microflora. A chapter focuses on the multiple aspects of plant sterol chemistry, function, and metabolism. The last chapters examine the mechanism of insect utilization and metabolism of dietary sterol. These chapters also cover the role of lipids in viral structure and metabolism. This book will prove useful to lipid chemistry, biochemists, and researchers.

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