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Books in Life sciences

  • New Insights in Pediatric Holter Monitoring and Interpretation

    • 1st Edition
    • Gabriel Cismaru + 2 more
    • English
    New Insights in Pediatric Holter Monitoring and Interpretation is the cutting edge book required by pediatric cardiologists and other professionals who encounter arrhythmias in children. Holter ECG examination has recently undergone significant advances in technology, sensors, and software. Yet, these innovations have been considered primarily in the context of adult patients. On the contrary, New Insights in Pediatric Holter Monitoring and Interpretation uses a case-based methodology to illustrate diagnosis and management of actual pediatric patients. Further, it offers guidance in deciding when referrals are necessary for arrhythmological consultations or ablation interventions. This book also contains novel techniques for detecting and interpreting pediatric arrhythmias. These include the introduction of Poincare graphs, Lorenz plots, and other advanced methods for assessing heart rate variability. New Insights in Pediatric Holter Monitoring and Interpretation modernizes readers' understanding of arrhythmias in children, thus improving the young lives of those in their care.

  • Neurogenetic Therapies

    Advancements in Treating Nervous System Disorders
    • 1st Edition
    • Ashutosh Pareek + 4 more
    • English
    Neurogenetic Therapies: Advancements in Treating Nervous System Disorders offers a comprehensive resource on the latest gene therapy techniques and their applications in treating neurological disorders. The book delves into various gene therapy methods, including genomic DNA-based therapies, vector-mediated delivery, and RNA interference-based gene silencing. It explores the use of these techniques in treating conditions such as Alzheimer's disease, Parkinson's disease, spinal muscular atrophy, and Duchenne muscular dystrophy. Key topics include the molecular and genetic basis of nervous system disorders, the role of epigenetics, and the development of stem cell and genome editing therapies.With contributions from leading experts, the book also addresses regulatory and ethical considerations in gene therapy, providing a balanced perspective on the challenges and opportunities in this rapidly evolving field. Case studies and practical examples illustrate successful gene therapy treatments, offering valuable insights into translating research into clinical practice. This book is an essential resource for students, researchers, and scientists in neurogenetics, neurology, and molecular biology, as well as clinicians interested in the mechanisms and treatment of neurodegenerative diseases.

  • A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management

    • 1st Edition
    • Scott G. Pritzlaff + 4 more
    • English
    A Comprehensive Guide to Dorsal Root Ganglion Stimulation for Pain Management explores the theoretical foundations, clinical applications, and technical nuances of DRG stimulation, providing a robust framework for understanding and implementing this advanced pain management technique. The book consolidates current best practices, novel technical considerations, and emerging research into a single, authoritative volume. Main themes include the anatomical and physiological basis of DRG stimulation, clinical indications, patient selection, surgical techniques, device programming, and long-term patient outcomes. By integrating insights from leading experts in the field, the book provides a comprehensive and practical guide for clinicians, researchers, and students. Distinct from existing titles that merely touch upon the subject, this book offers a detailed and specialized focus on DRG stimulation, including up-to-date evidence, clinical guidelines, and case studies. The book also features pedagogical elements such as learning objectives, review questions, and case studies to enhance understanding and application.

  • Genome Damage

    Repair and Adaptation Across Life
    • 1st Edition
    • Vinod K. Kannaujiya + 2 more
    • English
    Genome Damage: Repair and Adaptation Across Life explores the significance of nucleic acid damage from environmental pollutants, UV radiation, and other stressors that can lead to mutations, genetic instability, and various diseases, including cancer. This book delves into the mechanisms of DNA and RNA repair, which are crucial for maintaining cellular health and enabling evolutionary adaptations. It examines these intricate processes across microbes, plants, and animals, providing a comprehensive understanding of how genetic materials are regulated and repaired under diverse environmental conditions.Other sections cover a wide range of topics, including advanced molecular mechanisms of nucleotide repair, UV-induced damage, apoptosis cell death and autophagy, genetic instability in crops, and the role of post-translational modifications in DNA repair, the detection and quantification of DNA damage, the impact of synthetic chemicals and climate change on nucleic acids, and the therapeutic significance of DNA repair mechanisms. The book closes with a look towards future perspectives.

  • The Future of Health and Economic Resiliency in Africa

    • 1st Edition
    • Muhammad Pate + 1 more
    • English
    Grown out of a Lancet Commission to look at the future of health and economic resiliency of Africa, The Future of Health and Economic Resiliency takes a multidisciplinary approach across numerous sectors of analysis, central to Africa’s future well-being. This book serves as a comprehensive analysis of the current state of the continent and what actions can be taken to improve health and resiliency moving forward. While previous analysis has been done regionally within the continent (sub-Saharan Africa, for example) or by specific health needs (HIV or poverty, for example), this book will be the first to synthesize a cross sector approach pan-Africa. By describing the context and through actionable solutions for the future, this book sets the framework for a more resilient Africa and global future. Future of Health and Economic Resiliency is a collaboration of top African experts and practitioners in public health, health systems, economics, financing, nutrition, climate, youth representation, and the private sector.

  • Encyclopedia of Psychotherapy

    • 2nd Edition
    • David Reitman + 1 more
    • English
    The Encyclopedia of Psychotherapy, Second Edition, Three Volume Set covers the major psychotherapies currently in practice as well as the classical approaches that laid the foundation for the various contemporary treatment approaches. In addition, the encyclopaedia identifies the scientific studies conducted on the efficacy of the therapies and review the theoretical basis of each therapy.The new edition has been thoroughly updated from the first edition, focusing on major modes of psychotherapy practice and core psychotherapy processes. Outdated entries have been culled or combined with other entries in a manner that better communicates the content to present-day readers (e.g., “water-misting therapy” can be addressed in a more cohesive entry covering the use of punishment techniques more generally).

  • Apolipoprotein E in Health and Disease

    Unravelling its Intricate Roles
    • 1st Edition
    • Dileep Kumar + 2 more
    • English
    Apolipoprotein E in Health and Disease: Unravelling its Intricate Roles delves into the multifaceted functions of Apolipoprotein E (ApoE) across various health conditions and diseases. This comprehensive volume offers an in-depth exploration of ApoE, illuminating its structural insights, functional significance, and genetic variability. Each chapter examines the role of ApoE in different disease contexts, including cardiovascular diseases, Alzheimer's disease, neurological disorders, metabolic syndrome, liver health, cancer, and inflammatory disorders. Key chapters investigate ApoE's impact on lipid metabolism, atherosclerosis, and heart health while also probing its involvement in genetic predispositions and mechanistic implications in Alzheimer's disease. In addition, the book extends its exploration to the broader influence of ApoE on cognitive decline and other neurological conditions, metabolic health, liver function, cancer risk, and immune modulation. With a strong focus on the pharmacogenetics of ApoE, the book paves the way for precision medicine, offering insights into how ApoE genotypes influence medication responses and therapeutic strategies. Future prospects and challenges in harnessing ApoE for disease management are discussed, alongside its role in infectious diseases, genetic engineering innovations, and targeted drug delivery systems.

  • Space Physiology

    From Earth to Space and Back Again
    • 1st Edition
    • Alan Hargens
    • English
    Space Physiology: From Earth to Space and Back Again provides readers with new and authoritative information about current and important topics related to risks in space. The book covers translation of Earth-based physiology to astronaut health and Earth applications of space research. Topics include adaptations of various systems to space, including bone, microcirculation, microcirculation, skeletal and smooth muscles, headward fluid shifts as well as integrated countermeasures to maintain well-being and health in space.This is a volume in Elsevier’s new series Hot Topics in Physiology, published in association with the International Union of Physiological Sciences (IUPS). It is an ideal reference for academics and researchers (space physiology and medicine, rehabilitation medicine, biochemistry and cell biology, molecular biology) at Undergrad, Masters, PhD, and Post-Doc levels.

  • Radiation Biology

    Molecular Foundations and Clinical Applications
    • 1st Edition
    • Barry S. Rosenstein + 1 more
    • English
    Radiation Biology: Molecular Foundations and Clinical Applications is a comprehensive exploration of the effects of radiation on living organisms, delving into the molecular mechanisms underlying cellular responses. This book examines critical topics such as radiation-induced DNA damage, repair processes, and molecular signaling pathways. It provides a detailed look at how cells respond to radiation, addressing cell cycle control, apoptosis, and the effects of radiation on immune system functionality. As a resource for researchers, it bridges the gap between molecular biology and clinical oncology, offering insights into radiation's role in both therapeutic contexts and its broader impact on human biology.In addition to its focus on molecular responses, the book covers topics like tumor microenvironment and metabolism, the role of epigenetics in radiation biology, and the hallmarks of cancer relevant to radiation therapy. It also provides discussions on chemotherapeutic agents, radiation carcinogenesis, and the complex interplay between radiation and cancer biology. The later sections extend the scope to tissue, organ, and systemic effects of radiation, making it an invaluable reference for professionals in molecular biology, oncology, and related fields striving to push the boundaries of radiation research.

  • Rhythm and Entrainment in Neuromodulation

    • 1st Edition
    • James R. Evans + 2 more
    • English
    Rhythm and Entrainment in Neuromodulation covers cutting-edge and up-to-date information on currently available rhythm-related treatment procedures, as well as the interplay between music and cognition. The book contains contributions from leading experts in the across several fields, exploring the ways in which rhythmic stimulation serves as a powerful neuromodulator, enhancing cognitive function and promoting healing. Best suited for clinicians and researchers interested in neuromodulation, this volume offers profound insights into how rhythm shapes our cognition, influences our well-being, and paves the way for innovative therapeutic practices.

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