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Books in Life sciences

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    • Encyclopedia of Marine Mammals

      • 3rd Edition
      • November 24, 2017
      • Bernd Würsig + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 4 3 2 7 1
      • eBook
        9 7 8 0 1 2 8 0 4 3 8 1 3
      The Encyclopedia of Marine Mammals, Third Edition covers the ecology, behavior, conservation, evolution, form and function of whales, dolphins, seals, sea lions, manatees, dugongs, otters and polar bears. This edition provides new content on anthropogenic concerns, latest information on emerging threats such as ocean noise, and impacts of climate change. With authors and editors who are world experts, this new edition is a critical resource for all who are interested in marine mammals, especially upper level undergraduate and graduate students, researchers, and managers, and is a top reference for those in related fields, from oceanographers to environmental scientists.

    • Inhaled Pharmaceutical Product Development Perspectives

      • 1st Edition
      • November 23, 2017
      • Anthony J. Hickey
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 2 0 9 9
      • eBook
        9 7 8 0 1 2 8 1 2 3 3 6 2
      Inhaled Pharmaceutical Product Development Perspectives: Challenges and Opportunities describes methods and procedures for consideration when developing inhaled pharmaceuticals, while commenting on product development strategies and their suitability to support regulatory submission. It bridges the gap between the aspirations of scientists invested in new technology development and the requirements that must be met for any new product. The book brings together emerging analytical and inhalation technologies, providing perspectives that illuminate formulation and device design, development, regulatory compliance, and practice. Focusing on underlying scientific and technical principles known to be acceptable from the current regulatory perspective, this monograph will remain useful as a high-level guide to inhaled product development for the foreseeable future.

    • CRISPR in Animals and Animal Models

      • 1st Edition
      • Volume 152
      • November 10, 2017
      • English
      • Hardback
        9 7 8 0 1 2 8 1 2 5 0 6 9
      • eBook
        9 7 8 0 1 2 8 1 2 5 0 7 6
      CRISPR in Animals and Animal Models, Volume 152, the latest release in the Progress in Molecular Biology and Translational Science series, explores the genome editing CRISPR system in cells and animal models, its applications, the uses of the CRISPR system, and the past, present and future of CRISPR genome editing. Topics of interest in this updated volume include a section on CRISPR history, The genome editing revolution, Programming CRISPR and its applications, CRISPR Delivery methods, CRISPR libraries and screening, CRISPR investigation in haploid cells, CRISPR in the generation of transgenic animals, CRISPR therapeutics, and Promising strategies and present challenges.

    • Designing EEG Experiments for Studying the Brain

      • 1st Edition
      • May 25, 2017
      • Aamir Saeed Malik + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 1 1 4 0 6
      • eBook
        9 7 8 0 1 2 8 1 1 1 4 1 3
      Designing EEG Experiments for Studying the Brain: Design Code and Example Datasets details the design of various brain experiments using electroencephalogram (EEG). Providing guidelines for designing an EEG experiment, it is primarily for researchers who want to venture into this field by designing their own experiments as well as those who are excited about neuroscience and want to explore various applications related to the brain. The first chapter describes how to design an EEG experiment and details the various parameters that should be considered for success, while remaining chapters provide experiment design for a number of neurological applications, both clinical and behavioral. As each chapter is accompanied with experiment design codes and example datasets, those interested can quickly design their own experiments or use the current design for their own purposes. Helpful appendices provide various forms for one’s experiment including recruitment forms, feedback forms, ethics forms, and recommendations for related hardware equipment and software for data acquisition, processing, and analysis.

    • Principles and Practice of Clinical Research

      • 4th Edition
      • November 16, 2017
      • John I. Gallin + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 4 9 9 0 5 4
      • eBook
        9 7 8 0 1 2 8 4 9 9 0 4 7
      Principles and Practice of Clinical Research, Fourth Edition has been thoroughly revised to provide a comprehensive look at both the fundamental principles and expanding practice of clinical research. New to this edition of this highly regarded reference, authors have focused on examples that broadly reflect clinical research on a global scale while including a discussion of international regulations, studies, and implications. In addition to key topics such as bioethics, clinical outcome data, cultural diversity, protocol guidelines, and “omic” platforms, this edition contains new chapters devoted to electronic health records and information resources for clinical researchers, as well as the many opportunities associated with big data. Covering a vast number of topics and practical advice for both novice and advanced clinical investigators, this book is a highly relevant and essential resource for all those involved in conducting research.

    • Environmental Factors in Neurodegenerative Diseases

      • 1st Edition
      • Volume 1
      • September 19, 2017
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 7 6 4 3
      • eBook
        9 7 8 0 1 2 8 1 2 7 6 5 0
      Environmental Factors in Neurodegenerative Diseases, Volume One addresses contemporary advances in neurotoxicology, with thematic volumes providing authoritative review articles on key issues in the field. Updates in this new volume include chapters on Air pollution and neurodegenerative diseases, Mercury and Parkinson’s disease, Pesticides and PD: current evidence, Aluminum and neurodegeneration, Microglia and neurodegeneration, Dietary factors, Mitochondria in neurodegeneration, and Manganese and neurodegeneration. Edited by leading experts, volumes are designed as in-depth overviews of the latest topic developments that analyze the effect of varied chemical agents on the nervous system. It is an essential resource for researchers and graduate students alike.

    • Mathematics for Neuroscientists

      • 2nd Edition
      • February 4, 2017
      • Fabrizio Gabbiani + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 1 8 9 5 8
      • eBook
        9 7 8 0 1 2 8 0 1 9 0 6 1
      Mathematics for Neuroscientists, Second Edition, presents a comprehensive introduction to mathematical and computational methods used in neuroscience to describe and model neural components of the brain from ion channels to single neurons, neural networks and their relation to behavior. The book contains more than 200 figures generated using Matlab code available to the student and scholar. Mathematical concepts are introduced hand in hand with neuroscience, emphasizing the connection between experimental results and theory.

    • Comparative Anatomy and Histology

      • 2nd Edition
      • August 29, 2017
      • Piper M. Treuting + 2 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 9 0 0 8
      • eBook
        9 7 8 0 1 2 8 1 3 8 8 3 0
      • eBook
        9 7 8 0 1 2 8 0 2 9 1 9 0
      The second edition of Comparative Anatomy and Histology is aimed at the new rodent investigator as well as medical and veterinary pathologists who need to expand their knowledge base into comparative anatomy and histology. It guides the reader through normal mouse and rat anatomy and histology using direct comparison to the human. The side by side comparison of mouse, rat, and human tissues highlight the unique biology of the rodents, which has great impact on the validation of rodent models of human disease.

    • Vegetarian and Plant-Based Diets in Health and Disease Prevention

      • 1st Edition
      • May 23, 2017
      • François Mariotti
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 9 6 8 7
      • eBook
        9 7 8 0 1 2 8 0 3 9 6 9 4
      Vegetarian and Plant-Based Diets in Health and Disease Prevention examines the science of vegetarian and plant-based diets and their nutritional impact on human health. This book assembles the science related to vegetarian and plant-based diets in a comprehensive, balanced, single reference that discusses both the overall benefits of plant-based diets on health and the risk of disease and issues concerning the status in certain nutrients of the individuals, while providing overall consideration to the entire spectrum of vegetarian diets. Broken into five sections, the first provides a general overview of vegetarian / plant-based diets so that readers have a foundational understanding of the topic. Dietary choices and their relation with nutritional transition and sustainability issues are discussed. The second and third sections provide a comprehensive description of the relationship between plant-based diets and health and disease prevention. The fourth section provides a deeper look into how the relationship between plant-based diets and health and disease prevention may differ in populations with different age or physiological status. The fifth and final section of the book details the nutrients and substances whose intakes are related to the proportions of plant or animal products in the diet.

    • The Rewiring Brain

      • 1st Edition
      • June 21, 2017
      • Arjen van Ooyen + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 7 8 4 3
      • eBook
        9 7 8 0 1 2 8 0 3 8 7 2 7
      The adult brain is not as hard-wired as traditionally thought. By modifying their small- or large-scale morphology, neurons can make new synaptic connections or break existing ones (structural plasticity). Structural changes accompany memory formation and learning, and are induced by neurogenesis, neurodegeneration and brain injury such as stroke. Exploring the role of structural plasticity in the brain can be greatly assisted by mathematical and computational models, as they enable us to bridge the gap between system-level dynamics and lower level cellular and molecular processes. However, most traditional neural network models have fixed neuronal morphologies and a static connectivity pattern, with plasticity merely arising from changes in the strength of existing synapses (synaptic plasticity). In The Rewiring Brain, the editors bring together for the first time contemporary modeling studies that investigate the implications of structural plasticity for brain function and pathology. Starting with an experimental background on structural plasticity in the adult brain, the book covers computational studies on homeostatic structural plasticity, the impact of structural plasticity on cognition and cortical connectivity, the interaction between synaptic and structural plasticity, neurogenesis-related structural plasticity, and structural plasticity in neurological disorders. Structural plasticity adds a whole new dimension to brain plasticity, and The Rewiring Brain shows how computational approaches may help to gain a better understanding of the full adaptive potential of the adult brain. The book is written for both computational and experimental neuroscientists.

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