Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.
After reports of adverse events associated with energy drink consumption, including trouble sleeping, anxiety, cardiovascular events, seizures, and even death, concerns have been raised about their safety and efficacy. Energy Drinks: Composition, Consumption, and Cautions will focus on these popular beverages, their composition, ingredients, consumption patterns, performance-enhancing effects, and their potential negative side effects and health risks. This book will go on to make recommendations that call for education, regulatory actions, changes in marketing, and additional research.The research about energy drink safety and efficacy is often contradictory, and much of the available literature is industry sponsored. This book will offer a single, unbiased, up-to-date resource for researchers, healthcare providers, and industry regulators to understand the full scope of energy drinks and their associated health risks.
Clinical Applications of Echo Doppler Haemodynamics is precisely the book cardiologists and cardiology trainees have been waiting for. While this essential area of echocardiography is crucial to cardiologists and all cardiac imagers, there are no dedicated books for case-based Doppler Echocardiography. This often-overlooked discipline integrates physiology with interpretation of a wide variety of real-life echo Doppler tracings. It contains critical information for professionals around the world, including contents highly relevant to their day-to-day practice as well as its unique case studies. An abundance of knowledge in this area can currently be found randomly in various textbooks, but they lack cohesive, dedicated explanations and discussions. Clinical Applications of Echo Doppler Haemodynamics presents the reader with 100 different Doppler images, exemplifying (among other things) cardiophysiology image analysis, LVOT, pulmonary pressures, shunts, congenital heart disease and ECMO. It quite literally gives medical professionals a new way to look at the heart, better allowing them to diagnose and treat previously under-identified ailments. It is a must-have for healthcare workers interested in the most accurate, up-to-date methods of cardiac imaging and Doppler interpretation.
Early Detection of Alzheimer’s Disease: Biological and Technological Advances aims to introduce to a wide audience the high global priority problem of detecting AD prior to dementia onset. According to the Alzheimer’s Association, 5.8 million Americans are living with Alzheimer’s and care costs will cost the nation approximately $290 billion (2019 Alzheimer’s Disease Facts and Figures). With the failure of recent AD drug trials, many hypothesize that by the time symptoms appear, it is too late to be treated. Early detection can offer benefits such as more choice of medications, ability to participate in clinical trials, more time for family and for care planning. This book outlines potential solutions to the above problem using opportunities arising from the technology revolution, advances in neuroscience, and molecular biology. Most importantly, it discusses a paradigm shift from a reactive to a proactive diagnostic approach, aiming to detect disease before occurrence of symptoms. Topics covered include the use of sensing technologies (e.g. smartphones, smartwatches, Internet of Things) to detect early disease-related changes, the application of data science (machine learning/AI) to extract otherwise invisible disease features from these datasets and the potential to personalize diagnosis based on tracking changes in individual behaviours. Advances in blood-based biomarkers, brain imaging, and the potential for early diagnosis to aid interventions (lifestyle, dietary, pharmacological) to delay future development of dementia are also discussed.
Intelligent Nanobiosystems in Medicine and Healthcare, Volume One: Fundamentals, Fabrication and Commercialization provides an overview of recent progress in the nanobiosystems arena, helping readers design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancement in cutting-edge nanomedical technologies. It highlights established research and technology on intelligent nanobiosystems, their rapidly emerging aspects, and future research directions. Sections cover nanobiosystems, explore nano candidates and fabrication aspects, and delve into the challenges of commercialization.This book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, biochemical and biomedical engineers working both in academia and industry.
Intelligent Nanobiosystems in Medicine and Healthcare, Volume 2: Applications of Intelligent Nanobiosystems provides recent progress in the nanobiosystems arena, helping readers better design and develop novel drug delivery systems and devices that take advantage of recent advances in nanomedical technologies. The book explores a wide range of promising approaches for the diagnosis and treatment of diseases using the latest advancements in cutting-edge nanomedical technologies. This updated volume includes chapters by experts in the field, featuring an exploration of targeted therapy and drug delivery systems, analytical and imaging tools, theranostics, tissue engineering and regenerative medicines, dentistry tools and modern developments.This book will be a useful resource for researchers and postgraduate students in pharmaceutical sciences and biotechnology industries as well as medical professionals, biologists, chemists, materials scientists, clinical researchers, and biochemical and biomedical engineers working both in industry and academia.
Driven to the brink of extinction by the maritime fur trade, sea otter recovery is a remarkable success story, one with broad implications to our understanding of their life history, ecology, and socio-ecology. Sea Otter Conservation II: Nearshore Ecosystem Restoration summarizes current knowledge regarding sea otter recovery and the role it plays in the restoration and resilience of coastal systems. Written by experts in the field, this volume describes the influence of sea otters in kelp, seagrass, salt marsh, and mixed sediment communities, and how their ecological effects can link marine and terrestrial systems. The authors consider the ecological and socio-ecological consequences of the maritime fur trade, the ways in which abundant food and space have affected sea otter recovery, and the potential of future sea otter reintroductions to aid their recovery and that of related ecosystems. This book reviews the latest methods in monitoring sea otter behavior, population status and genetic diversity, and the impact of climate change on sea otters and their associated communities. Sea Otter Conservation II: Nearshore Ecosystem Restoration is an important resource for anyone studying ecology, conservation, or restoration.
Handbook of Spinal Anesthesia introduces the theoretical and practical aspects of administering spinal anesthesia. The book's chapters explore the anatomy of the spine and the mechanism of action of a neuraxial block, as well as the pharmacology of local anesthetics in this area. Sections also include guidance for assessing risks on a patient-by-patient basis and feature a range of administration techniques. Information on pre-operative patient care, patient monitoring and post-operative care is also included. The book considers complications and challenges in performing spinal anesthesia and closes with a chapter on recent advances in the field. This book acts as a comprehensive foundation to spinal anesthesia. It is an ideal reference for junior doctors, medical officers, and non-specialist physicians seeking a practical guide to performing spinal anesthesia.
Diagnostic Landscape in Cancer Landscape examines the combined impact of prevention, diagnosis, and treatment of cancer. With a strong focus on the status, challenges, and prospects of diagnostic tools and technology, the book also examines the clinical translation-related knowledge and prognosis of different organ related cancers. In 22 chapters, the book describes current and new diagnostic tools in twenty different cancers and explores how innovations in the cancer diagnostic space could make cancer screening and early detection more straightforward.This book is a timely and valuable resource for health professionals, scientists, researchers, health practitioners, students, and all those who wish to broaden their knowledge in the allied field.
Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omic offers an advanced exploration into the comprehensive understanding of disease etiology and prognosis through multiomics approaches. This authoritative volume delves into the applications of multiomics technology in elucidating complex human health conditions and diseases. It introduces the technology's potential for biomarker identification, drug discovery, and disease prognostication. For a thorough understanding of human health and diseases, particularly cancer, it is essential to integrate knowledge of molecular biomarkers across multiple omics levels, including the genome, epigenome, transcriptome, proteome, and metabolome. This resource addresses the current gaps in knowledge among students and researchers, providing in-depth coverage of multiomics technology and its implementation in scientific research and discovery.Multi-Omics Technology in Human Health and Diseases: Genomics, Epigenomics, Transcriptomics, Proteomics, Metabolomics, Radiomics, Multi-omics is a pioneering resource that presents cutting-edge information on contemporary multiomics technologies for big data interpretation and their applications in deciphering complex human pathobiology. This comprehensive guide is indispensable for researchers, academics, students, and industry professionals alike.