
How Sex and Gender Impact Clinical Practice
An Evidence-Based Guide to Patient Care
- 2nd Edition - November 1, 2025
- Imprint: Academic Press
- Editors: Marjorie R. Jenkins, Connie B. Newman
- Language: English
- Paperback ISBN:9 7 8 - 0 - 4 4 3 - 2 6 7 1 2 - 3
- eBook ISBN:9 7 8 - 0 - 4 4 3 - 2 6 7 1 3 - 0
How Sex and Gender Impact Clinical Practice: An Evidence-Based Approach to Patient Care, Second Edition is an essential resource for primary care clinicians seeking to integr… Read more

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Request a sales quoteHow Sex and Gender Impact Clinical Practice: An Evidence-Based Approach to Patient Care, Second Edition is an essential resource for primary care clinicians seeking to integrate sex and gender differences into their practice. This edition emphasizes the unique application framework that assists practitioners in providing personalized care. It aligns sex and gender medicine with precision medicine, helping health care providers attract patients who value clinicians that understand the nuances of sex and gender in healthcare.
This updated edition updates evidence-based information on disease prevalence, diagnosis, testing, and treatment. It covers new topics such as sex differences in thyroid disease, pain, and hypertension. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.
This updated edition updates evidence-based information on disease prevalence, diagnosis, testing, and treatment. It covers new topics such as sex differences in thyroid disease, pain, and hypertension. Each chapter reflects how sex and gender impact disease presentation, physical examination, testing, treatment, and clinical decision-making.
- Includes Case Studies and Tables that summarize Sex and Gender Differences in a disease
- Provides Gaps in Knowledge and Practice Points for the physician
- Presents a new way of looking at common diseases through a sex and gender lens
- Includes new chapters or subchapters on pain, hypertension, and thyroid disease
Biomedical researchers in endocrinology, cardiology, neuroscience, development biology, medical students, residents, and practicing physicians from all medical areas
Section I: The Importance of Sex and Gender in Patient Care
1. Application of Sex and Gender Health: A Practical Framework
2. Clinician-Patient Communication: Gender Influences
Section II: Sex and Gender Evidence in Health and Disease
3. Addiction: Sex and Gender Evidence in Alcohol, Tobacco, and Opioids Substance Use Disorders
4. Autoimmune Diseases: Sex and Gender Evidence in Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Ankylosing Spondylitis
5. Cancer Screening and Prevention: Sex and Gender Evidence in Lung, Breast, and Colorectal Cancer
6. Cardiovascular Disease: Sex and Gender Evidence in Acute Ischemic Syndrome and Heart Failure
7. Gastrointestinal Diseases: Sex and Gender Evidence in Liver Lesions, Gastroesophageal Reflux, and Inflammatory Bowel Disease
8. Mental Health: Sex and Gender Evidence in Schizophrenia, Depression, and Anxiety Disorders
9. Metabolic Disorders: Sex and Gender Evidence in Dyslipidemia, Diabetes, and Obesity
10. Musculoskeletal Disorders: Sex and Gender Evidence in ACL Injuries, Osteoarthritis, and Osteoporosis
11. Neurological Diseases: Sex and Gender Evidence in Stroke, Migraine, and Alzheimer’s Dementia
12. Pharmacology: Sex and Gender Evidence in Medication Safety and Efficacy
13. Public Health in Your Practice: Sex and Gender Considerations in Access to Healthcare, Immunizations, and Intimate Partner Violence
14. Respiratory Diseases: Sex and Gender Evidence in Obstructive Sleep Apnea, COPD, and Asthma
Section III: Beyond Point of Care: Sex and Gender Influences in the Community of Practice
15. The Business of Medicine: Making the Case for a Sex and Gender Practice
16. Knowledge Resources in Sex and Gender Health
17. Sex and gender differences in pain
18. Sex and gender differences in thyroid diseases
19. Sex and gender differences in hypertension
1. Application of Sex and Gender Health: A Practical Framework
2. Clinician-Patient Communication: Gender Influences
Section II: Sex and Gender Evidence in Health and Disease
3. Addiction: Sex and Gender Evidence in Alcohol, Tobacco, and Opioids Substance Use Disorders
4. Autoimmune Diseases: Sex and Gender Evidence in Rheumatoid Arthritis, Systemic Lupus Erythematosus, and Ankylosing Spondylitis
5. Cancer Screening and Prevention: Sex and Gender Evidence in Lung, Breast, and Colorectal Cancer
6. Cardiovascular Disease: Sex and Gender Evidence in Acute Ischemic Syndrome and Heart Failure
7. Gastrointestinal Diseases: Sex and Gender Evidence in Liver Lesions, Gastroesophageal Reflux, and Inflammatory Bowel Disease
8. Mental Health: Sex and Gender Evidence in Schizophrenia, Depression, and Anxiety Disorders
9. Metabolic Disorders: Sex and Gender Evidence in Dyslipidemia, Diabetes, and Obesity
10. Musculoskeletal Disorders: Sex and Gender Evidence in ACL Injuries, Osteoarthritis, and Osteoporosis
11. Neurological Diseases: Sex and Gender Evidence in Stroke, Migraine, and Alzheimer’s Dementia
12. Pharmacology: Sex and Gender Evidence in Medication Safety and Efficacy
13. Public Health in Your Practice: Sex and Gender Considerations in Access to Healthcare, Immunizations, and Intimate Partner Violence
14. Respiratory Diseases: Sex and Gender Evidence in Obstructive Sleep Apnea, COPD, and Asthma
Section III: Beyond Point of Care: Sex and Gender Influences in the Community of Practice
15. The Business of Medicine: Making the Case for a Sex and Gender Practice
16. Knowledge Resources in Sex and Gender Health
17. Sex and gender differences in pain
18. Sex and gender differences in thyroid diseases
19. Sex and gender differences in hypertension
- Edition: 2
- Published: November 1, 2025
- Imprint: Academic Press
- Language: English
- Paperback ISBN: 9780443267123
- eBook ISBN: 9780443267130
MJ
Marjorie R. Jenkins
Dr. Jenkins serves as the Dean at the School of Medicine Greenville, Associate Provost University of South Carolina, and Chief Academic Officer for Prisma Health Upstate. She has served many additional leadership roles such as Director of Medical Initiatives and Scientific Engagement at the U.S. Food and Drug Administration Office of Women’s Health (OWH); Graduate Research Program Director, Master of Education for Health Professions at Johns Hopkins University, College of Education, Professor of Internal Medicine, and Founding Director and Chief Scientific Officer for the Laura W. Bush Institute at Texas Tech University Health Sciences Center; She is a founder and past co-chair of the National Sex and Gender in Health Professions Education Summit. She is nationally and internationally known in the area of sex and gender-specific clinical care, research application, and health professions curriculum development.
Affiliations and expertise
Dean at the School of Medicine Greenville, Associate Provost University of South Carolina, and Chief Academic Officer for Prisma Health Upstate, USACN
Connie B. Newman
Adjunct Professor of Medicine at the New York University Grossman School of Medicine, is Board Certified in Internal Medicine, Endocrinology and Metabolism, and Obesity Medicine. She is a Fellow of the American College of Physicians, the American Heart Association, the American Medical Women’s Association (AMWA), and the New York Academy of Medicine. She served as the 2018-2019 President of AMWA, an organization of women physicians, pre-medical and medical students that advocates for advancement of women in medicine, health equity and sex and gender based medical education. Dr. Newman is recognized for her expertise in hypercholesterolemia, hypertriglyceridemia, statin safety, and randomized controlled clinical trials. She is the Chair of the 2020 Endocrine Society clinical practice guideline on the management of dyslipidemia in endocrine diseases, and served as Chair of the writing group for the American Heart Association’s 2019 Scientific Statement on the safety of statins. Dr. Newman is an appointed member of the FDA Endocrine and Metabolic Disorders Advisory Committee. Dr. Newman writes and speaks on the topics of sex and gender health, high cholesterol and heart disease, and statin safety. She is the recipient of the 2020 Bertha Van Hoosen Award, named for the founder of AMWA. She is featured in “20 Women, 20 Years”, an online exhibit of leaders in the medical profession, sponsored by the Women in Medicine Legacy Foundation.
Affiliations and expertise
Adjunct Professor of Medicine, Division of Endocrinology, Diabetes and Metabolism, NYU Grossman School of Medicine, NY, USA