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Books in Life sciences

  • The Exposome in Cancer Disparities

    Influence of Environmental and Infectious Factors in LMICs
    • 1st Edition
    • Zodwa Dlamini
    • English
    The Exposome in Cancer Disparities: Influence of Environmental and Infectious Factors in LMICs examines how environmental and infectious factors drive cancer inequities in low- and middle-income countries (LMICs). The book introduces the exposome as a comprehensive framework to understand complex risk factors, such as environmental toxins, climate change, and infectious agents like HPV and HIV. The book combines scientific insights, real-world case studies, and practical strategies from international experts, highlighting region-specific contributors to cancer disparities. Structured into thematic sections, it offers a holistic view of the challenges faced by LMICs and provides actionable, evidence-based solutions tailored to resource-limited settings.The work emphasizes the importance of multidisciplinary approaches and international collaboration to develop effective prevention and policy strategies. It will benefit researchers, policymakers, and healthcare professionals by deepening understanding of cancer risk factors, fostering global cooperation and guiding targeted interventions to reduce health inequities and improve outcomes worldwide.

  • Explainable AI in Clinical Practice

    Advanced Applications and Future Directions
    • 1st Edition
    • Saurav Mallik + 4 more
    • English
    Explainable AI in Clinical Practice: Advanced Applications and Future Directions builds on foundational concepts to explore the practical implementation and emerging trends of transparent AI in healthcare. Featuring contributions from leading experts, this volume presents advanced methodologies, real-world case studies across various medical specialties, and strategies for overcoming ethical, regulatory, and operational challenges. The book offers comprehensive frameworks for integrating explainable AI into clinical workflows, emphasizing trust, patient understanding, and regulatory compliance. In addition, it examines future technologies such as federated learning, multimodal systems, and human-AI collaboration, providing insights into the evolving landscape of AI in medicine.Essential for healthcare professionals, researchers, and policymakers, this volume aims to accelerate the responsible adoption of explainable AI, ultimately enhancing patient care, clinical decision-making, and healthcare system efficiency.

  • Barrier Membranes in Regenerative Dentistry

    From Concepts to Clinical Applications and Bioengineering
    • 1st Edition
    • Mehrdad Lotfazar
    • English
    Barrier Membranes in Regenerative Dentistry: From Concepts to Clinical Applications and Bioengineering provides the first comprehensive book dedicated to the science, technology, and clinical practice of barrier membranes in regenerative periodontal and implant therapy. Bridging foundational biology with state-of-the-art innovations, this authoritative volume traces the historical evolution of barrier membranes, examines their material and biological properties, and explores their therapeutic applications in guided tissue regeneration (GTR) and guided bone regeneration (GBR). Structured as both a scholarly reference and a practical clinical guide, the book spans the continuum of membrane technologies—from early passive barriers to today’s bioenhanced, gene-activated, and tissue-engineered platforms.Each chapter integrates scientific principles with real-world surgical applications that are supported by more than 500 clinical and scientific illustrations and over 1,000 peer-reviewed references. Concise summary boxes, clinical implications, and key conclusions at the end of each chapter reinforce learning and support evidence-based decision-making. Unique features include comprehensive coverage of both degradable and non-degradable membranes, comparative analysis of material classes, and forward-looking perspectives on biofunctional and personalized regenerative approaches.

  • Epigenetic Mechanisms in Brain Physiology and Disorders

    • 1st Edition
    • Moshe Szyf + 1 more
    • English
    Epigenetic Mechanisms in Brain Physiology and Disorders provides a comprehensive summary of epigenetic mechanisms in brain development, from embryogenesis to aging, brain physiology and pathology. It discusses the role DNA methylation plays in regulating genomic functions, which in turn guide brain function. The book explores the epigenetic role in cell type differentiation, epigenetic processes in memory, learning, and neuronal functioning, the role of DNA methylation and other epigenetic mechanisms in sleep, feeding and metabolic control, sex, temperature regulation, and cardiovascular and blood pressure regulation. It further explores the role of epigenetic processes in neuropsychiatry disorders, neurological disease and behavioral disorders, as well as epigenetic diagnostics and therapeutics.

  • Transposable Elements in Health and Disease

    • 1st Edition
    • Volume 116
    • English
    Transposable Elements in Health and Disease, Volume 116 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Specific chapters examine Transposable Elements in Human Cancer: Regulation, Activation, and Genomic Consequences, Retrotransposons as both “architects” and “saboteurs” in the nervous system, Shaping Mammalian Genomes: The Regulation and Co-option of Transposable Elements, Transposable element analysis in -omics data, and Transposable elements in Aging: from biomarkers to effectors.Together, these contributions provide valuable insights into the mechanisms and impacts of transposable element activity, advancing our understanding of their broad significance in genetics, development, health, and disease.

  • Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics

    Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations
    • 1st Edition
    • Naresh Kasoju + 1 more
    • English
    Mesenchymal Stem Cells and Extracellular Vesicles as Next-Generation Therapeutics: Basic Concepts, Clinical Applications, and Cross-Disciplinary Innovations provides a comprehensive exploration of the groundbreaking roles stem cells and extracellular vesicles (EVs) play in regenerative medicine. The book examines the fundamental biology of stem cells and EVs, their therapeutic applications across tissues - including skin, neural, cardiac, ocular, and more and the innovative, interdisciplinary approaches shaping the future of healthcare. Sections cover Basic and Emerging Concepts, Therapeutic Applications and Disease Focus, and Cross-disciplinary Innovations and Future Directions the field will encounter in this rapidly growing branch of medicine.Written by experts in the field for researchers and academics engaged in regenerative medicine, stem cell biology, and biomedical engineering, this book will be of interest to healthcare professionals such as physicians, surgeons, and specialists interested in tissue repair and regeneration.

  • Smart Aquaponic Farming

    An Intelligent Production System for Aquaponics
    • 1st Edition
    • Daoliang Li
    • English
    Smart Aquaponic Farming: An Intelligent Production System for Aquaponics describes the aquaponics AI factory, an ecologically efficient and sustainable multitrophic production model. While traditional aquaculture systems produce farming waste with environmental and food safety implications, the aquaponics model offers a circular organic production method that recycles and reuses aquatic waste to expand the ecological planting scene. Given recent developments in intelligent sensing, information processing, and agricultural equipment technologies, this book provides a much-needed technical guide for industry scientists and technicians. Written by leading experts in aquaculture biosystems engineering, this book reviews technology assembly, system realization, and industrial development of intelligent aquaponics AI factory models. Early chapters introduce the concept of AI factory infrastructure before exploring recirculating aquaculture systems, hydroponic planting systems, and various control systems to maintain air quality, water quality, and fish nutrition. Concluding chapters discuss AI factory system integration, sustainability evaluation, and global case studies of proof-of-concept systems. Smart Aquaponic Farming provides in-depth conceptual analyses, technical overviews, and case presentations to demonstrate the characteristics, advantages, and significance of industrial scale-up for aquaponics. It bridges the gap in disseminated knowledge on analysis, design, and implementation of aquaponics AI factories, making it an indispensable resource for aquaponics producers, technicians, industry scientists, and academics alike.

  • Fundamentals of Translational Tissue Engineering

    • 1st Edition
    • Yogesh Kumar Verma + 3 more
    • English
    Fundamentals of Translational Tissue Engineering explores the practical dimensions of tissue engineering (TE), outlining the intricate path of development of tissue engineered products. The book navigates the reader through the fundamental aspects and challenges in TE, equipping the reader with insights crucial to comprehending the journey a tissue engineered product traverses on its way to clinical translation. The first section, Material Sciences, provides the reader with a general overview covering the basics of scaffolds, biomaterials and techniques, while the larger, second section, Biological and Clinical Aspects, discussing the biological perspectives relating to tissue engineering.This is a multi-disciplinary work that will be ideal for audiences of varying levels of expertise, from the novice exploring fundamental concepts or the seasoned professionals seeking comprehensive information, readers of all backgrounds will be able to access and benefit from this tailored approach.

  • Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging

    • 1st Edition
    • Mohammad Sufian Badar
    • English
    Diagnosis and Analysis of Glaucoma using AI and ML for Medical Imaging highlights the importance of early detection while also discussing and updating on current treatment options to slow disease progression, emphasizing the role of AI and ML in improving diagnosis and management. Sections explore causes, symptoms, diagnostic challenges, and treatment strategies for glaucoma, integrating insights on how artificial intelligence and machine learning models can enhance healthcare delivery. Practical case studies and discussions on how accessible AI tools can be utilized by healthcare workers, NGOs, students, and researchers to address diagnostic barriers prevalent in resource-limited settings are included. This targeted resource is aimed at increasing understanding of this often asymptomatic, progressive eye disease, particularly in developing countries. Healthcare professionals, students, and policymakers will find this resource valuable with its straightforward, easy to understand, curriculum-aligned content. Its emphasis on practical applications and awareness-building make it a valuable tool for advancing glaucoma care and fostering interdisciplinary collaboration in eye health.

  • Modern fMRI

    Practical Lessons and Insights
    • 1st Edition
    • Andrew Jahn
    • English
    The field of neuroimaging with functional magnetic resonance imaging (fMRI) is developing at a rapid pace, with a seemingly endless number of software packages, statistical methods, and different ways to organize and analyze neuroimaging data. Among such a wide variety of options, and with so many seemingly conflicting pieces of advice on the “correct” way of analyzing neuroimaging data, knowing what decisions to make is a difficult task. Modern fMRI: Practical Lessons and Insights provides an up-to-date, holistic overview of the field of fMRI, familiarizing the reader with the latest trends in neuroimaging, such as standardized data organization and preprocessing, advances in functional connectivity and machine learning, and current guidelines in data and code sharing. This includes advice about best practices in preprocessing, statistical modeling, QA checks, and some of the latest tools and concepts to be familiar with, including fMRIPrep, OpenNeuro.org, Open Science practices, and Jupyter notebooks

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