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Books in Life sciences

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  • Saffron

    Science, Technology and Health
    • 1st Edition
    • Alireza Koocheki + 1 more
    • English
    Saffron: Science, Technology and Health summarizes the scientific, technical and health aspects of this crop. Saffron possesses unique agronomical, ecological, social and physiological characteristics. And, there are various chemical components present in saffron, including carbohydrates, minerals, vitamins, color pigment, aromatic and flavoring agents. Saffron has a long history of use in traditional medicine, and in recent years, the application of saffron in the medical industry as a cancer curing and antidepressant agent has brought more attention. There is also a growing trend of saffron use in the conventional food industry, including saffron desserts, cream, butter, beverages, powders, cake mixes and soups. Intended for nutrition scientists and scientists and technologists working in the areas of food, agriculture, new product development and pharmacology.

  • Advances in Agronomy

    • 1st Edition
    • Volume 159
    • Donald L. Sparks
    • English
    Advances in Agronomy, Volume 159, the latest release in this leading reference on agronomy, contains a variety of updates, including specific chapters on the Environmental Behavior of Glyphosate in Soil, Agriculture Contingency Plans for Managing Weather Aberrations and Extreme Climate Events: Development, Implementation and Impacts in India, Unmanned Aircraft Systems for Precision Weed Management Applications: Prospects and Challenges, Ratoon Rice Technology: A Green and Resource-Efficient Way for Rice Production, Growth Characteristics of Winter Wheat in China Based on GDD Comprehensive and Quantitative Analysis of Growth Characteristics of Winter Wheat in China Based on Growing Degree Days, and more.

  • An Innovative Approach to Understanding and Treating Cancer: Targeting pH

    From Etiopathogenesis to New Therapeutic Avenues
    • 1st Edition
    • Tomas Koltai + 2 more
    • English
    An Innovative Approach to Studying and Treating Cancer: Targeting pH describes one of the few characteristics of cancer that is not shared by normal tissues: the reversal or inversion of the pH gradient when intracellular pH becomes alkaline and extracellular pH becomes acid. This is now recognized as one of the most selective and differential hallmarks of all cancer cells and tissues, being the opposite of the condition found in normal tissues and a potential target in order to achieve either a stable disease or even regression with no toxicity. The book discusses topics such as lactic acid and its transport system in the pH paradigm, mechanisms to decrease extra cellular pH and increase intracellular pH, NHE-1 activity in cancer, carbonic anhydrases, vacuolar ATPase proton pump, and the sodium-bicarbonate cotransporter system. Additionally, it discusses complementary pharmacological interventions, cellular acidification and extracellular alkalinization as a new and integral approach to cancer treatment.

  • Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors

    • 1st Edition
    • Volume 169
    • English
    Oligomerization in Health and Disease: From Enzymes to G Protein-Coupled Receptors, Volume 169 in the Progress in Molecular Biology and Translational Science series, provides in-depth reviews on topics of exceptional scientific importance. Topics of note in this new release include Computational prediction and re-design of aberrant oligomerization, Oligomerization of G protein-coupled receptors: an historical overview, Prediction and targeting of GPCR oligomer interfaces, GPCR Oligomerization dynamics: Functional consequences, GPCR heteromerization in neuropsychiatric disorders, Structural basis of regulation and oligomerization of human cystathionine β-synthase, and Oligomerization of Porphobilinogen Synthase.

  • Neurological Modulation of Sleep

    Mechanisms and Function of Sleep Health
    • 1st Edition
    • Ronald Ross Watson + 1 more
    • English
    Neurological Modulation of Sleep provides readers with updated scientific reviews regarding the interaction between sleep and contributing factors, with special attention paid to the potential for neurological modulation of sleep via diet. This book expands the notion of diet and adds an element of physical activity and exercise as well as a chapter on caffeine and its effects on sleep. With 30+ international contributors, this book aims to provide readers with a unique global perspective on the role these factors plays in sleep architecture and its regulation by circadian biology and neurology. Sleep disorders have become an increasing problem plaguing more than 70 million Americans according to the American Sleep Association. There is a clear association between sleep disorder and a wide range of other human disorders –performance deficiencies, psychiatric illnesses, heart disease, obesity and more – but in spite of this there is not yet a convenient overview on the market detailing the impact of obesity, age, diabetes and diet on sleep duration and attendant health outcomes.

  • Neural Networks Modeling and Control

    Applications for Unknown Nonlinear Delayed Systems in Discrete Time
    • 1st Edition
    • Jorge D. Rios + 3 more
    • English
    Neural Networks Modelling and Control: Applications for Unknown Nonlinear Delayed Systems in Discrete Time focuses on modeling and control of discrete-time unknown nonlinear delayed systems under uncertainties based on Artificial Neural Networks. First, a Recurrent High Order Neural Network (RHONN) is used to identify discrete-time unknown nonlinear delayed systems under uncertainties, then a RHONN is used to design neural observers for the same class of systems. Therefore, both neural models are used to synthesize controllers for trajectory tracking based on two methodologies: sliding mode control and Inverse Optimal Neural Control. As well as considering the different neural control models and complications that are associated with them, this book also analyzes potential applications, prototypes and future trends.

  • Deep Learning Techniques for Biomedical and Health Informatics

    • 1st Edition
    • Basant Agarwal + 4 more
    • English
    Deep Learning Techniques for Biomedical and Health Informatics provides readers with the state-of-the-art in deep learning-based methods for biomedical and health informatics. The book covers not only the best-performing methods, it also presents implementation methods. The book includes all the prerequisite methodologies in each chapter so that new researchers and practitioners will find it very useful. Chapters go from basic methodology to advanced methods, including detailed descriptions of proposed approaches and comprehensive critical discussions on experimental results and how they are applied to Biomedical Engineering, Electronic Health Records, and medical image processing.

  • Tumor Immunology and Immunotherapy – Cellular Methods Part A

    • 1st Edition
    • Volume 631
    • English
    Tumor Immunology and Immunotherapy – Cellular Methods Part A, Volume 631, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. New chapters include Detection of intracellular cytokine production by T cells with flow cytometry, High-throughput identification of human antigen-specific CD8+ and CD4+ T cells using soluble pMHC multimers, In vitro assays for effector T cell functions and activity of immunostimulatory antibodies, Ex vivo energetic profiling of tumor cells and T cells from mouse models and human samples, A cytofluorimetric assay to evaluate T cell polyfunctionality, and much more.

  • Gene Environment Interactions

    Nature and Nurture in the Twenty-first Century
    • 1st Edition
    • Moyra Smith
    • English
    Gene Environment Interactions: Nature and Nurture in the Twenty-first Century offers a rare, synergistic view of ongoing revelations in gene environment interaction studies, drawing together key themes from epigenetics, microbiomics, disease etiology, and toxicology to illuminate pathways for clinical translation and the paradigm shift towards precision medicine. Across eleven chapters, Dr. Smith discusses interactions with the environment, human adaptations to environmental stimuli, pathogen encounters across the centuries, epigenetic modulation of gene expression, transgenerational inheritance, the microbiome’s intrinsic effects on human health, and the gene-environment etiology of cardiovascular, metabolic, psychiatric, behavioral and monogenic disorders. Later chapters illuminate how our new understanding of gene environment interactions are driving advances in precision medicine and novel treatments. In addition, the book's author shares strategies to support clinical translation of these scientific findings to improve heath literacy among the general population.

  • Protein Misfolding

    • 1st Edition
    • Volume 118
    • Rossen Donev
    • English
    Protein Misfolding, Volume 118, covers the wide spectrum of diseases and disorders that are attributed to protein misfolding, including degenerative and neurodegenerative, cardiovascular, renal, glaucoma, cancer, cystic fibrosis, Gaucher's disease, and many others. Specific chapters cover Mass spectrometric approaches for profiling protein folding and stability, Biomembranes, a key player in protein misfolding, how Genetic and environmental factors interact to disrupt proteostasis and trigger protein misfolding diseases, Formation of oligomers and large amorphous aggregates by intrinsically disordered proteins, Protein misfolding in ER stress with applications to cardiovascular and renal disease, and much more.

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