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Elsevier

Books in Life sciences

  • Glucose Transporters

    • 1st Edition
    • Volume 128
    • English
    Glucose Transporters, Volume 128 in the Vitamins and Hormones series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics, including Glucose transporters and their energy homeostasis function in various organs, Molecular basis for inhibiting glucose transporters by exofacial inhibitors, Self-assembly of the insulin-responsive vesicles creates a signaling platform for the insulin action on glucose uptake, The role of lipid soluble vitamins on glucose transporter, Transport of dehydroascorbic acid by glucose transporters GLUTs, Glut-1 Inhibition in Breast Cancer Cells, Small-molecule inhibitors of glucose transporters, and more.

  • Differentiating Factors in Alzheimer’s Disease

    Gender, Ethnicity, Clinical and Treatment
    • 1st Edition
    • Henry M. Zeidan + 1 more
    • English
    Differentiating Factors in Alzheimer’s Disease: Gender, Ethnicity, Clinical and Treatment addresses the question why women differ from men in terms of their risk factors and how Alzheimer's disease can be prevented at the molecular level. This book reviews the epidemiology of Alzheimer's disease describing the differences in men's and women's brain anatomy and biochemistry that may account for why women are more likely to develop Alzheimer's disease. The authors offer actions that could help to prevent or slow the progression of Alzheimer's disease in addition to discussing the most recent pharmacological treatments.

  • Emerging Green Processing Technologies for Beverages

    • 1st Edition
    • Roji Waghmare + 1 more
    • English
    Emerging Green Processing Technologies for Beverages, Volume Seven in the Developments in Food Quality and Safety series, covers the fundamentals and recent trends in the processing of different beverages, such as herbal beverages, fresh produce-based beverages, and dairy beverages. Chapters cover a broad range of beverages to enhance knowledge in quality retention and shelf life extension. Sections summarize the influence of green technologies on nutritional quality, microbial safety, and physico-chemical characteristics. Edited by Dr. José Manuel Lorenzo and authored by a team of global experts, this book provides comprehensive knowledge to food industry personnel and scientists.This is the most up-to-date resource, covering trend topics such as Advances in the analysis of toxic compounds and control of food poisoning; Food fraud, traceability and authenticity; Revalorization of agrifood industry; Natural antimicrobial compounds and application to improve the preservation of food; Non-thermal processing technologies in the food industry; Nanotechnology in food production; and Intelligent packaging and sensors for food applications.

  • Cerebral Asymmetries

    • 1st Edition
    • Volume 208
    • English
    Cerebral Asymmetries, Volume 208 summarizes research on cerebral hemispheric asymmetries and their implication for consciousness cognition, language emotion, behavior movement, and neurological disease. The book discusses anatomy and networks, genetics, hormones, and evolution, although it is primarily focused on animal research as it relates back to humans.

  • The Immunology of the Domestic Ruminants

    Cattle, Sheep, and Goats
    • 1st Edition
    • Ian R. Tizard
    • English
    The Immunology of Domestic Ruminants: Cattle, Sheep, and Goats provides a thorough examination of the immune systems of these animals. It explores their normal immune functions and their roles in combating infectious and parasitic diseases, chronic inflammatory conditions, and immunodeficiency disorders. The book incorporates new data from the bovine genome project and highlights significant breed differences. Both innate and adaptive immunity are systematically covered, offering insights into basic and applied aspects of bovine immunology. In addition to detailing the immunology of major bacterial, viral, and parasitic diseases in cattle, the book reviews bovine vaccines and emphasizes the importance nutrition.This essential resource caters to professionals in large animal research and practice, providing comprehensive information on the immunology of domestic cattle, sheep, and goats.

  • Natural Biopolymers for Drug Delivery

    • 1st Edition
    • Amit Kumar Nayak + 2 more
    • English
    Natural Biopolymers for Drug Delivery thoroughly details the properties, benefits and challenges of using these biomaterials in drug delivery, with a strong focus on biocompatibility and reduction of unwanted interactions. An extensive range of natural biopolymers are explored, such as cellulose, chitosan, casein, gelatin, cashew gum, and many more. Biocompatibility, toxicity and regulatory considerations are also thoroughly discussed, ensuring the reader is fully equipped for efficient biomaterials selection and utilization in drug delivery applications. This is a must-have reference for those working in the fields of materials science, biomedical engineering, pharmaceutical science and pharmacology, chemical engineering and clinical science.

  • Cholecystokinin

    From Gallbladder to Cognition and Beyond
    • 1st Edition
    • Christine Feinle-Bisset + 1 more
    • English
    Cholecystokinin: From Gallbladder to Cognition and Beyond covers the biology, physiology, and pathophysiological roles of cholecystokinin (CCK) peptides. The book begins with a historical overview before providing in-depth chapters on the biology of CCK, from biogenesis to cell expression, including intestinal and extraintestinal endocrine cells, the central and peripheral nervous system, and receptor function. CCK phylogenesis is explored across various species, including fish, birds, insects and amphibians. The physiology of CCK covers intestinal CCK secretion, the gallbladder and pancreas, and the role of CCK in the gut-brain axis, gastrointestinal motor function, appetite regulation, and cardiovascular function.Methods used for CCK research are also discussed. A number of chapters then covers the roles of CCK in various diseases, including metabolic diseases, tumors, psychiatric illness, the immune system and nociception, as well as potential therapeutic approaches targeting CCK receptors.

  • Methods for Monitoring Mitochondrial Functions During Pathogen Infection

    • 1st Edition
    • Volume 194
    • English
    Methods for Monitoring Mitochondrial Functions During Pathogen Infection, Volume 194 in the Methods in Cell Biology series highlights advances in the field, with this new volume presenting interesting chapters on timely topics, including Mitochondrial Labeling with Fluorescent Proteins for Enhanced Morphological Characterization and Visualization of Intercellular Mitochondrial Transfer, Visualizing mitochondrial electron transport chain complexes and super-complexes during infection of human macrophages with Legionella pneumophila, Quantitative assessment of mitochondrial membrane potential in macrophages in sepsis, Quantification of mitochondrial reactive oxygen species in macrophages during sepsis, and much more.Additional chapters cover Quantification of intracellular and mitochondrial ATP content in macrophages during lipopolysaccharide-i... inflammatory response, Analysis of cytosolic mtDNA release during Staphylococcus Aureus infection, Monitoring mitochondria dynamics upon infection using a tomographic approach, A screening system to determine bacterial effects on MADCAM1 expression by high endothelial venule cells, Isolation of mitochondria from Mycobacteria infected cells, Monitoring mitochondrial localization of Mycobacterial proteins, and more.

  • La maladie de Parkinson

    • 5th Edition
    • Luc Defebvre + 2 more
    • French
    La collection « Elsevier Monographies » permet aux praticiens d’approfondir et d’actualiser leurs connaissances, en exposant les données fondamentales actuelles et leurs applications dans la pratique clinique.La maladie de Parkinson est, après la maladie d’Alzheimer, l’affection neurologique la plus répandue au sein de la population après 50 ans. Sa prévalence augmentant avec l’âge, surtout au-delà de 60 ans, on peut prévoir dès aujourd’hui qu’avec le vieillissement de la population, le nombre de patients ne cessera d’augmenter dans les années à venir.Modèle d’affection neurodégénérative, la maladie de Parkinson se manifeste de façon variable selon les patients et les stades d’évolution, bien au-delà des seuls troubles moteurs qui la caractérisent. Ces dernières années, la recherche a connu des avancées significatives, tant sur le plan de la compréhension des mécanismes physiopathologiques et génétiques que sur celui des stratégies diagnostiques et thérapeutiques.Cette cinquième édition, réalisée en collaboration avec les meilleurs spécialistes cliniciens et chercheurs francophones, propose une actualisation complète des connaissances, enrichie de neuf nouveaux chapitres. Cette nouvelle édition aborde ainsi des thématiques essentielles comme l’histoire et l’épidémiologie de la maladie, les innovations en électrophysiologie, la santé bucco-dentaire, les indications des injections de toxine botulique ou encore le rôle du pharmacien d’officine. De plus, une attention particulière a été portée à la démarche neuropalliative, aux dispositifs de soins à domicile et aux questions pratiques telles que le permis de conduire.Ce livre s’adresse aux praticiens et à tous les professionnels de santé, médicaux et paramédicaux, exerçant dans un service de neurologie ou concernés par la pathologie parkinsonienne : neurologues, internes préparant le diplôme d’études spécialisées de neurologie, neuropsychologues, psychiatres, rééducateurs, orthophonistes et kinésithérapeutes.PO... CLÉSL’histoire et l’épidémiologie de la maladie.Les causes, la physiopathologie et les signes cliniques.La prise en charge thérapeutique des patients. Luc Defebvre est chef du service de neurologie et pathologie du mouvement, responsable du Centre Expert Parkinson, unité Inserm 1172, CHU et université de Lille.Marc Vérin est neurologue au service de neurologie, CHU d’Orléans, laboratoire interdisciplinaire pour l’innovation et la recherche en santé d’Orléans (LI2RSO), équipe « Brain Clinical and Experimental Neuroplasticity » (B-CLINE), université d’Orléans.

  • The Nervous System

    • 1st Edition
    • Volume 5
    • Mayeen Uddin Khandaker + 1 more
    • English
    The series Stem Cell Innovation in Health and Disease is a timely and fascinating collection of information and new discoveries and provides a contemporary snapshot album from the fast-moving field of regenerative medicine and stem cell therapeutics. The Nervous System, Volume 5 addresses the recent data accumulated on the potential applications of stem cells to treat diseases and disorders of the nervous system. This volume will highlight the recent development of cutting edge in vitro and in vivo research tools and approaches, including human and murine organoid cultures, genetic editing in vitro and in vivo, human iPSC models of disease, haploid cells for genetic as well as compound screening paradigms, genetically engineered mice, and stem cell transplantation to treat nervous system disorders and diseases. The volume is written for researchers and scientists in stem cell therapy, cell biology, regenerative medicine and organ transplantation; and is contributed by world-renowned authors in the field.

  • Innovations in Biomedical Engineering

    Trends in Scientific Advances and Applications
    • 1st Edition
    • Shubham Mahajan + 1 more
    • English
    Innovations in Biomedical Engineering: Trends in Scientific Advances and Application addresses the burgeoning demand for a comprehensive resource that not only showcases the latest advancements in this dynamic field but also shows how these innovations can be effectively translated into real-world applications. In essence, the book acts as a bridge, connecting discoveries, research, and innovations in biomedical engineering to tangible, real-world applications.

  • African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance

    Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance
    • 1st Edition
    • Volume 115
    • English
    African Plant-Based Products as a Source of Potent Drugs to Overcome Cancers and their Chemoresistance: Part 3. Potential Pharmaceuticals to Overcome Cancers and their Chemoresistance offers detailed information on the best cytotoxic phytoconstituents of African medicinal plants that could be useful for the development of efficient pharmaceuticals that could be further explored to efficiently overcome cancers and their drug resistance. The book identifies and comments on the various classes of cytotoxic African secondary metabolites. The book also clearly identifies and comments on the best cytotoxic molecules identified in African medicinal plants. The book appears an amazing tool for Scientists to have state-of-the-art of the best cytotoxic phytoconstituents from the African flora, and to boost their clinical investigations.

  • Foodborne and Microorganisms

    Spoilage and Pathogens and their Control
    • 1st Edition
    • Volume 113
    • English
    Foodborne and Microorganisms: Spoilage and Pathogens and their Control, Volume 110 in the Advances in Food and Nutrition Research series, updates on the latest developments in this evolving science. Chapters in this new release include Understanding the potential of fresh produce as vehicles of Salmonella enterica, Modeling and Optimization of Non-thermal Technologies for Animal-origin Food Decontamination, Space food production on safety and quality: Hazard Analysis and Critical Control Points (HACCP) plan and quality control methods, Inactivation of foodborne pathogens by nonthermal Technologies, Foodborne sporeforming bacteria: challenges and opportunities for their control through food production chain, and more.Additional sections focus on Spoilage microorganisms in the dairy industry, Foodborne pathogens in the pork production chain, Food spoilage fungi: main sources and controlling strategies, Advanced data analytics and ‘omics’ techniques to control enteric foodborne pathogens, and Prevention of foodborne virus and pathogens in fresh produce and root vegetables.

  • Necrobotics for Healthcare Applications and Management

    • 1st Edition
    • Hemachandran Kannan + 4 more
    • English
    Necrobotics for Healthcare Applications and Management delves into the emerging area of necrobotics and its implications for healthcare. Exploring the convergence of robotics, technology, and healthcare, the book presents leading-edge research, practical implementations, and ethical considerations. It bridges a significant gap in healthcare literature, furnishing a contemporary and comprehensive perspective on necrobotics. Highlighting its distinct applications, management nuances, and ethical dimensions in the domain of medical robotics, the book equips readers with an in-depth grasp of this evolving field. It offers insights into technological intricacies, practical utilization, and ethical guidelines. Through real-world case studies and exemplar practices, it vividly demonstrates successful necrobotics deployments while addressing integration challenges. The book facilitates adept navigation of necrobotics complexities, spur innovation, enhance patient outcomes, and contribute to healthcare evolution. Catering to the distinct information requisites and daily obstacles encountered by engineers, healthcare practitioners, and researchers, the book offers extensive insights into necrobotics technologies, real-life case studies, and ethical reflections. It stands as a valuable resource for individuals striving to harness necrobotics' potential for efficacious healthcare solutions.

  • An Insider's Guide to Academic Publishing in Orthopaedic and Spine Surgery

    • 1st Edition
    • Andrew J. Schoenfeld
    • English
    An Insider's Guide to Academic Publishing in Orthopaedic and Spine Surgery provides detailed guidelines on the design, execution, synthesis, and communication of research. It is divided into four sections: General Considerations, Conduct of the Research and Writing, Submission Strategy, and Post-Production. Each section offers practical advice and insights to help researchers navigate the complex process of academic publishing. Additionally, the book covers preparing a CV and building a research program, making it an invaluable tool for students, post-grads, residents, and fellows who seek direction in publishing articles or presenting at conferences.Authored by a leader in orthopedic and spine surgery, this guide aims to enhance the academic success of individuals at various stages of their careers.

  • Microplastics in Agriculture and Food Science

    Methods for Identification and Remediation
    • 1st Edition
    • Pasquale Avino + 2 more
    • English
    Microplastics in Agriculture and Food Science: Methods for Identification and Remediation presents fundamental insights into the sources of microplastics and their impact on important agricultural, food, and environmental resources. Presenting insights into these highly related fields, this book is the first to enable cross- and multidisciplinary understanding and application.Micropla... are tiny particles created during plastic production as well as those particles remaining when plastic degrades and breaks down. They are sometimes difficult to identify, and the methods for qualifying and classifying them are not always clear despite the importance of their recognition and remediation. With insights into analytical methods including the challenges, this book addresses microplastics from the farm to the food pyramid, highlighting the issues they raise and the options for removing them.Written by a global team of experts, this volume contributes to further understanding and addressing of this increasing global challenge, and is an excellent resource for researchers in agricultural science, environmental science, and food science (particularly food chemistry and food packaging).

  • "Functionally" Single Ventricle

    The Most Complex Congenital Heart Defect
    • 1st Edition
    • Antonio F. Corno
    • English
    "Functionally" Single Ventricle: The Most Complex Congenital Heart Defect covers the most recent knowledge, methodologies, and techniques for diagnosing, managing, and treating pediatric patients with the "functionally" single ventricle congenital heart defect. The book covers epidemiology, ethnicity, racial issues, socioeconomic factors, fetal diagnosis, interventions, various treatment options available to pediatric patients, currently obtainable outcomes, and rescue plans after failure of conventional managements. In addition, it offers the potential for a wide range of future studies. Clinicians and researchers alike will find this title to be an invaluable one-stop resource for improving outcomes of pediatric patients with this complex congenital heart defect.

  • Lipids in Pulmonary Drug Delivery

    • 1st Edition
    • Md Faiyazuddin + 3 more
    • English
    Lipid in Pulmonary Drug Delivery explores the most recent advancements, strategies, and state-of-the-art technological progress in the development of lipid-based nanocarriers for pulmonary administration. The book presents wide coverage of various lipid-based nano-drug carriers such as liposomes, solid lipid nanoparticles, and nanoemulsions intended for the administration of drugs through the pulmonary route to treat different conditions. It also includes a general description of the formulation aspects of various lipid-based drug delivery vehicles, post-production processing, and biofate aspects with special emphasis on the pulmonary microenvironment.In addition, the authors include an update on the clinical status of the potential lipid nanocarriers used for effective management of the pulmonary related diseases. Written in a technical way covering the latest advancements in lipid-based drug delivery for pulmonary administration, this book is a useful reference for researchers, scientists, and graduate and postgraduate students working on, or planning, research in the field of lipid-based nano-drug pulmonary delivery platforms.

  • Antimicrobial Food Packaging

    • 2nd Edition
    • Jorge Barros-Velazquez
    • English
    Antimicrobial Food Packaging, Second Edition continues to be an essential resource covering all aspects in the development and application of novel antimicrobial films to all types of packaged foods. The book is organized in six parts to include the main backgrounds and frameworks of the topic, types of packaging materials and packaging systems and the migration of packaging elements into food, the most relevant established and emerging technologies for microbial detection in food systems, the development and application of antimicrobial packaging strategies to specific food sectors, and the most promising combinational approaches, also including combinational edible antimicrobial coatings.Useful to a wide audience of researchers, scientists, and students, the new edition brings five new chapters that include the latest information on smart packaging for monitoring food quality, postbiotics in antimicrobial packaging applications, emerging hydrocolloids from food processing waste or novel antimicrobial packaging strategies in dairy products.

  • Coma, Stupor, and Related Disorders of Consciousness

    • 1st Edition
    • Volume 207
    • Peter W. Kaplan + 1 more
    • English
    Coma, Stupor, and Related Disorders of Consciousness reviews recent research and best practice in the assessment and treatment of coma, stupor, and disorders of consciousness. It encompasses the neural circuits, anatomy & physiology of stupor and coma, differential diagnosis and clinical assessment, imagery, EEGs, therapy/intervention... decision making and prognosis.

  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 125
    • English
    Advances in Clinical Chemistry, Volume 125, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists. Content covered in this new release includes, Spotting Targets with 2D-DIGE Proteomics, Extracellular Vesicles and MicroRNAs in Cancer Progression, Brain white matter damage biomarkers, Cell-cell junctional proteins in cancer, Advances in Periodontal Healing Biomarkers, and Preeclampsia and Eclampsia: Role of Hemolytic Protozoan Iron.

  • Brave Genomes

    Microbial Genome Plasticity in the Face of Environmental Challenge
    • 1st Edition
    • Silvia Bulgheresi
    • English
    **2026 PROSE Award Category Winner in Biomedicine and Neuroscience**The role of environmentally triggered genetic and epigenetic changes in microbial adaptation and evolution is still not broadly appreciated. Brave Genomes: Microbial Genome Plasticity in the Face of Environmental Challenge narrates how microorganisms cope with environmental changes including unanticipated ones. Although it does comprise eukaryotes, it focuses on bacteria and – whenever possible – on archaea.Among the environmentally sensitive sources of genome plasticity, the book treats tandem repeats, mutagenic break repair, transcription-associ... mutagenesis and transposable elements. Additionally, it deals with epigenetic mechanisms such as DNA methylation and regulatory RNA-based systems. These not only regulate the activity of mobile DNA, they can also synergize with it. In closing, symbiosis and genetic noise are also discussed as possible sources of phenotypic plasticity.Brave Genomes emphasizes the role of the environment in generating genotypic and phenotypic diversity. This emerges, in turn, as the most efficient response to challenging conditions.

  • TRNA-derived RNAs

    • 1st Edition
    • Volume 711
    • English
    tRNA-derived RNAs series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Genetic and Genome-Wide Microbial Insights: Bioenergy

    Microbial Genomics Volume 3
    • 1st Edition
    • Javid Ahmad Parray + 2 more
    • English
    Genetic and Genome-Wide Microbial Insights: Bioenergy: Microbial Genomics (Volume 3) delves into the cutting-edge developments in the field of metagenomics, encompassing both metatranscriptomics and metaproteomics. This comprehensive resource highlights the significant potential of metagenomics in screening previously uncultivated microbial species. It underscores the pivotal role of these advanced genomic techniques in accessing elusive microorganisms, thereby revolutionizing the production of biofuels. This book emphasizes the practicality of these methods, aiming to make biofuel production more economically feasible and efficient. "Genetic and Genome-Wide Microbial Insights: Bioenergy" offers both a foundational overview and the most recent advancements in microbial genomics, computational genomics, and enzyme engineering. It details the process of upscaling and bio-prospecting microbial strains, specifically tailored for biofuel production, providing a comprehensive guide that bridges basic concepts with cutting-edge research. This book covers a range of topics, including advanced microbial fuel production techniques, Sustainable bioenergy (genomics and biofuel development) and microbial engineering. The comprehensive chapters in this book will appeal to readers from diverse backgrounds in biology, life sciences, agriculture, environmental engineering, genome engineering, and even medicine.

  • Host Adaptation, Virulence, and Evolution

    Microbial Genomics Volume 1
    • 1st Edition
    • Javid Ahmad Parray + 2 more
    • English
    Microbial Genomics: Host Adaptation, Virulence, and Evolution covers different aspects of microbial genomics, metagenomics, and functional studies of microbes that have provided a significant understanding of microbial-host interactions, virulence function, host adaptation mechanisms, including microbial evolution. Microbial Genomics: Host Adaptation, virulence, and Evolution is a comprehensive source on the latest updates and applications of microbial genomics information to understand the plant, microbe interaction, host adaptation, virulence nature of the infectious pathogen, microbial evolution, host-pathogen interactions contribute to shaping the genetic diversity of both organisms. Sections include an introduction to Microbial Genomics, followed by sections on Plant Microbiome, Genome Editing Prospecting and Approaches, Microbial virulanse and disease incidence. The final section of the book covers Microbial Genomics and evolutionary concepts. “Microbial Genomics: Host Adaptation, virulence, and Evolution” is a valuable resource for faculty members, researchers, and undergraduate and postgraduate students at universities, medical research labs, industries, and government agencies that are interested in the microbial science specific to the microbial genome, virulence function of pathogenic microbes, host adaptation, evolution of microbes, and all other disciplines related to molecular microbiology.

  • Environmental Remediation in Agri-Food Industry Using Nanotechnology and Sustainable Strategies

    • 1st Edition
    • Predrag Putnik + 1 more
    • English
    Environmental Remediation in Agri-Food Industry Using Nanotechnology and Sustainable Strategies presents remediation practices to remove environmental pollutants caused by food manufacturing processes. The book explores AOPs, BiOX photocatalysts, perovskite materials, Zirconium oxide-based nanocomposites, and heterostructured semiconductor nanomaterials. It looks at environmental pollutants from the meat industry, fish production, horticulture, grains and other food manufacturing, and explores remediation of soil, water, and air. Contributors represent expertise from backgrounds in materials chemistry, nanotechnology, environmental chemistry, green technologies, analytical and physical chemistry, and agricultural and food science, providing a multidisciplinary approach for use in industry and public policy toward solving food security and environmental issues.

  • Introduction to Pharmaceutical Technology Development

    Journey from Lab to Shelf of Commercial Pharmaceutical Drugs
    • 1st Edition
    • Yaser Dahman
    • English
    Introduction to Pharmaceutical Technology Development: Journey from Lab to Shelf of Commercial Pharmaceutical Drugs is a complete reference and learning resource for those working in pharmaceutics or aspiring to join the industry. The book provides a comprehensive view into all aspects of drug discovery, approval, and production. Using examples of well-known drugs and their journeys from lab to market, the book provides a comprehensive overview of all steps involved in bringing new drugs, including biologics, to the shelves.Topics covered include Drug Discovery, Pharmaceutical Formulations of Different Dose Form, Analytical Testing and Development, Unit Operations and Design for Major Equipment, Basics of Analytics and Process Validations and Protocols (DQ, IQ, OQ, PQ) in FDA-Regulated Industries.This book provides graduate students from several areas with a solid foundation of the Pharmaceutic industry across key stages on new drug lifecycle.

  • Immunotherapy: Magic Bullet to Change the Future Therapeutics

    • 1st Edition
    • Volume 144
    • English
    FORMTEXT Immunotherapy is emerging as a novel and reliable therapeutic technique for treating diseases such as autoimmunity, HIV/AIDS, allergy and cancers. Immunotherapy change or modulate our immune system functionalization and activate it to kill pathogen infected cells or affected cells. Development in the field of Immunology, Molecular Biology, and Pharmaceutical Sciences empower the immune system for protecting us agaist number of pathogenic infections. This volume consisit of the chapters from the different stalwarts of the field coveriing the topic such as Immunotherapy past and present, Oncolytic virus based therapy, CAR-T cell therapy, antibody engineering, adjuvant engineering etc. Chapters covered in this volume discuss the immunological translational research in the field of human cancer, parasitic and infectiouds diseases. This volume incudes the chapter describing the tools developed by scientist to engineers safe and effective antibody which can be used as powerful medicine durig human disease conditions. This volume will reflect the secret of biological sciences and technology in the field on immunology to develop safe and efficacious immune molecules based magic bullet to provide absolute cure. This volume will be helpful to the early career researchers and students working in the field of basic and applied immunological sciences.

  • Circulating biomarkers for diagnosis, prognosis and treatment response prediction in cancer - Part A

    • 1st Edition
    • Volume 391
    • English
    Circulating Biomarkers for Diagnosis, Prognosis and Treatment Response Prediction in Cancer Patients, Part A, Volume 391 delves into the crucial role of circulating biomarkers in cancer diagnosis and treatment monitoring. Specific chapters in this new release include Circulating biomarkers for diagnosis and response to therapies in cancer patients, Identification of circulating tumor DNA as a biomarker for diagnosis and response to therapies in cancer patients, Identification of cell-free circulating epigenomic biomarkers for early diagnosis and response to therapies in breast cancer patients, Expanding frontiers in liquid biopsy-discovery and validation of circulating biomarkers in renal cell carcinoma and bladder cancer, and much more.This comprehensive work explores the various types of biomarkers, their significance in early cancer detection, prognostication, and evaluation of therapeutic responses. It covers cutting-edge research on circulating tumor cells, cell-free DNA, exosomes, and other biomarkers that can revolutionize cancer management. Additionally, it discusses the challenges, advancements, and future prospects of utilizing circulating biomarkers in personalized cancer care.

  • Recent Advances in Nanomedicines Mediated Wound Healing

    • 1st Edition
    • Prashant Kesharwani
    • English
    Recent Advances in Nanomedicines Mediated Wound Healing presents an overview of various nanotechnology-based drug delivery systems explored widely for wound healing. The book provides a comprehensive review of thriving strategies used for wound healing and thoroughly describes the most recent developments in emerging modern drug delivery systems with a focus on nanotechnology. It serves as a complete package for a holistic understanding of molecular pathways, conventional therapy, and novel nanocarrier-mediated drug delivery for wound healing while also exploring advanced strategies like siRNA and aptamer mediated approaches and nanomedicines to treat diabetic and full thickness wounds.This book will help researchers, undergraduates, graduate students, and experts in nanotechnology drug delivery and pharmaceutical related disciplines design and develop novel drug delivery systems and devices for wound healing that take advantage of recent advances in nanomedical technologies.

  • Imagerie de l'accident vasculaire cérébral ischémique aigu

    Méthode d'auto-apprentissage
    • 1st Edition
    • Valentin Lefèvre + 1 more
    • French
    L’imagerie constitue l’outil diagnostic indispensable dans la prise en charge des accidents vasculaires cérébraux (AVC), problème majeur de santé public. Elle permet d’orienter vers des choix thérapeutiques qui réduisent efficacement les risques de mortalité et de handicap.Conçu comme une méthode pratique qui regroupe l’ensemble des notions indispensables à la prise en charge d’un patient présentant un AVC, cet ouvrage se veut résolument pédagogique. Constitué d’une vingtaine de dossiers cliniques illustrés par une abondante iconographie, il propose au lecteur une démarche innovante en l’invitant à se confronter à des difficultés graduelles au fil des dossiers. Si l’apprentissage de l’imagerie est au coeur de ce livre, il aborde en complémentaritél’épi... la physiopathologie, l’anatomie, la clinique et la prise en charge thérapeutique.Cette démarche originale de graduation des connaissances et la structure des dossiers font de cet ouvrage un outil indispensable pour tous les professionnels, internes et praticiens, confrontés à la prise en charge des AVC. L’ouvrage s’adresse ainsi à un large public de médecins : radiologues, neurologues eturgentistes ou tout professionnel soucieux d’actualiser ou approfondir ses connaissances sur l’imagerie de l’AVC. Il favorise l’auto-apprentissage des uns et l’aide à la décision des autres.Ce livre a reçu la prix Hermann Fischgold 2025 décerné par la Société française de radiologie (SFR).Jean-Philippe Cottier est professeur des universités, praticien hospitalier, au sein du service de radiologie-neuroradi... diagnostique et interventionnelle au CHRU de Tours.Valentin Lefèvre est chef de clinique des universités, assistant des hôpitaux, au sein du service de radiologie-neuroradi... diagnostique et interventionnelle au CHRU de Tours.

  • The Science of Grapevines

    • 4th Edition
    • Markus Keller
    • English
    Fully revised and updated The Science of Grapevines, Fourth Edition is an introduction to the physical structure of the grapevine, its organs, their functions, and their interactions with the environment. Scientifically grounded and integrating discoveries in other plant species, it explores the physiological processes underlying grapevine form and function, their developmental and environmental control, and their implications for practical vineyard management. The book begins with a brief overview of the botanical classification, plant morphology and anatomy, and growth cycles of grapevines. It then covers the basic concepts in growth and development, water relations, photosynthesis and respiration, mineral uptake and utilization, and carbon partitioning. Then these concepts are put to use to understand plant-environment interactions including canopy dynamics, yield formation, and fruit composition. The book concludes with an introduction to stress physiology, including water and nutrient stresses, extreme temperatures, and the interaction with other organisms. Progress in the fields of grape cultivar evolution, grape ripening, and stress physiology has been rapid since edition 3 was published in 2020. Edition four reflects the latest insights into these and other key aspects of grapevine anatomy and physiology. Based on the author’s more than 30 years of teaching, research, and practical experience with grapevines and grape production, this book provides an important guide to understanding this fascinating and economically important plant. As a textbook for students and a reference for scientists and industry professionals, the book enables readers to use the discussed scientific concepts in their own research or practical production systems.

  • Advances in Agronomy

    • 1st Edition
    • Volume 190
    • English
    Advances in Agronomy, Volume 190, the latest release in this leading reference on agronomy, contains a variety of updates and highlights new advances in the field, each written by an international board of authors.

  • Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and Their Components

    • 2nd Edition
    • Mahendra Rai
    • English
    Fighting Multidrug Resistance with Herbal Extracts, Essential Oils and their Components, Second Edition offers pharmaceutical and life sciences researchers an overview on the most relevant studies for fighting specific multidrug-resistant (MDR) microorganisms such as bacteria, protozoans, viruses, and fungi using natural products. This new edition expands the coverage of uses of traditional medicinal plants to against MDR, includes new chapters on the potential of plant-derived bioactive compounds for reversal of multidrug resistances, covers the use of flavonoids to combat microbes and cancer, and the use of nanoparticles as drug delivery vehicle.The need to combat multidrug-resistant microorganisms is an urgent one. This book provides important coverage of mechanism of action, the advantages and disadvantages of using herbal extracts, essential oils and their components, and more, to aid researchers in effective antimicrobial drug discovery.

  • Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis

    • 1st Edition
    • Volume 211
    • English
    Osmolytes and Intrinsically Disordered Proteins: From Functional Regulation to Disease Pathogenesis, Volume 112 delves into the fascinating interplay between osmolytes and intrinsically disordered proteins (IDPs), exploring their pivotal roles in cellular function and disease mechanisms. This volume brings together experts to present cutting-edge research on how osmolytes regulate functional behavior of IDPs and ensure cellular stability and adaptability under stress conditions. Specific chapters cover Functional diversity of IDPs and their structural heterogeneity: Protein structure-function continuum, Osmolytes as structure-function regulators of intrinsically disordered casein, Synergism of the effects of osmolytes and crowders on structure and function of IDPs/IDRs: The natural habitat, and more.Additional chapters delve into Osmolyte-IDP Interactions during Desiccation, Modulation of aggregation/fibrilla... propensity of IDPs by osmolytes, Osmolytes in modulating the structural and functional integrity of α-synuclein: a study based on Parkinson's disease, Regulation of the structural dynamics, aggregation, and pathogenicity of polyQ-expanded Huntingtin by osmolytes, Aggregation and inhibitory strategies of amyloid fibrillation, and much more.

  • Navigating Endophytic Research for Next-Generation Therapeutics

    • 1st Edition
    • Vagish Dwibedi + 3 more
    • English
    Navigating Endophytic Research for Next-Generation Therapeutics explores the evolving field of endophytic fungal research and applications in combating diseases, addressing environmental challenges, and in shaping the future of therapeutics. The book starts off with a discussion on the biodiversity and biogeography of endophytic fungal communities and describes the bioprospecting of endophytes for drug discovery. In addition, it covers the therapeutic application of endophytic fungi to treat and manage specific diseases and investigates the innovative use of technologies such as genome editing, genetic engineering for enhanced bioactivity, multi-omics-based exploration, and the use of big data and machine learning in endophytic drug discovery.Featuring contributions from experts across fields like mycology, pharmacology, biotechnology, and environment science, this comprehensive, practical, and insightful resource guides those engaged in endophytic fungal research and its transformative potential in next-generation therapeutics.

  • Organic Mechanochemistry

    A New Tool for Sustainable Synthesis
    • 1st Edition
    • Davor Margetic
    • English
    Organic Mechanochemistry: A New Tool for Sustainable Synthesis presents the greener chemical method to a broader reading audience, including chemical practitioners. Descriptions of each method, followed by examples on sustainability aspects and applications give readers a better understanding and realization of its possibilities. Mechanochemistry, a nonconventional method for inducing the chemical reaction by application of mechanical energy in solid state, has been recognized as beneficial as mechanochemically conducted reactions hold diverse environmental sustainability advantages in manufacturing processes.

  • Colorectal Imaging

    From Basic to Advanced Concepts
    • 1st Edition
    • Luca Saba
    • English
    Colorectal Imaging: From Basic to Advanced Concepts provides an exhaustive overview of today’s basic and advanced principles of colorectal imaging, focusing not only on oncologic but also inflammatory, infective, and ischemic pathologies and complications. The book reviews basic colorectal cancer information, examines imaging techniques and analysis, and concludes with a review of non-neoplastic pathologies. It is a useful resource for scientists, physicians, and medical students in the discipline of radiology, highlighting the critical role of contemporary imaging in guiding clinical and surgical approaches and providing the knowledge needed to confidently choose the most appropriate imaging examination.

  • Plant Functional Traits

    Linking Climate and Ecosystem Functioning
    • 1st Edition
    • Manoj Kumar + 2 more
    • English
    Plant Function Traits: Linking Climate and Ecosystem Functioning, part of the Plant Biology, Sustainability and Climate Change series, presents a wholistic understanding of Plant Functional Traits. As global climate change advances, natural resources are facing increasing survival challenges, hence this book directly addresses that need, exploring the morphological, physiological, and phenological properties of a plant that can be used as a proxy to understand plant environment interactions. Users will find great illustrations throughout individual chapters, along with case studies that demonstrate applications of functional traits in classifying vegetation of a region into distinct type groups as Plant Functional Types (PFTs).Additional information includes applications in the development of new generation of Dynamic Global Vegetation Model (DGVM) and an understanding of the response of vegetation to changing environments.

  • Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases

    • 1st Edition
    • Anoop Kumar + 1 more
    • English
    Applications of Nanotherapeutics and Nanotheranostics in Managing Infectious Diseases discusses how nanotechnology aids in overcoming the existing traditional approaches in combating diseases. The book explores the emerging trends of using nanoparticles for nanotherapeutics and nanotheranostics and their role in the efficient diagnosis and treatment of infectious microbial diseases. Sections covers nanotherapeutic impregnated medical devices, nanotherapeutics as vaccines, related regulatory requirements, the application of nanotherapeutics and nanotheranostics in diagnosing and treating specific infectious diseases, including bacterial infections, viral infections, fungal infestations, parasitic infestations, and other infectious conditions.With chapter contributions from experts in the fields, this book offers a comprehensive reference for researchers, scientists, and industry professionals working on infectious diseases and the application of nanoparticles to effectively diagnose, treat, and manage them.

  • Biofarmacia y farmacocinética

    • 3rd Edition
    • Antonio Aguilar Ros + 3 more
    • Spanish
    Esta nueva edición actualiza plenamente contenidos y conceptos, abordando los principales modelos de cálculo de la Biofarmacia y Farmacocinética a través de la resolución de problemas, todo ello en un estilo riguroso y con una perspectiva eminentemente práctica. Incorpora nuevos capítulos sobre ajuste posológico en insuficiencia renal, y sobre modelos farmacocinéticos/far... (PK/PD), así como un capítulo final consistente en 50 cuestiones tipo test para estudio y repaso. Para esta edición se han incorporado además nuevos autores.Los capítulos comienzan con un breve repaso del esquema del modelo y de las ecuaciones que posteriormente se utilizan en los problemas, que se resuelven paso a paso a continuación. La obra está dirigida tanto a los estudiantes de la materia como a los profesionales de distintos ámbitos que deseen profundizar y ampliar sus conocimientos en Biofarmacia y Farmacocinética. Se ofrece acceso a la versión electrónica completa del libro a través de la plataforma VitalSource. Esta versión incluye los siguientes contenidos complementarios: Problemas extra por capítulo, con sus soluciones; Enlaces a archivos para la impresión de papel milimetrado y semilogarítmico para la elaboración de gráficas, Enlaces a archivos Excel (con complemento SOLVER) para el cálculo y elaboración de gráficas, mediante regresión no lineal de los distintos modelos de biofarmacia y farmacocinética que se desarrollan en el libro.

  • Update on Obesity, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 54-1
    • Caroline M. Apovian + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Drs. Caroline M. Apovian and Dong Wook Kim bring their considerable expertise to the topic of Update on Obesity. Top experts in the field cover the latest research regarding weight loss drugs, drug safety, pharmacotherapy, AI, and nutritional/lifestyl... changes for managing obesity.

  • The Auditory Cerebellum

    Function and Dysfunction
    • 1st Edition
    • Jos J. Eggermont
    • English
    The Auditory Cerebellum: Function and Dysfunction focuses on the sensory and cognitive aspects of the cerebellum, with an emphasis on hearing, speech, music, speaking, and singing. This book fills the gap for information needed in audiology and auditory neuroscience, tinnitus, and developmental disorders with a strong auditory component. This book starts with a general overview on the connectivity between the cerebellum and auditory subcortical and cortical areas, including general cortical networks. There are several chapters devoted to the timing aspects of the cerebellum underlying speech and music perception as well as motor aspects in speaking and singing.Also discussed is the role of the cerebellum in hearing impairment, tinnitus, developmental disorders with a strong auditory component, including dyslexia, autism, attention deficit, and hyperactivity disorder. Dr. Jos Eggermont, a leading researcher in the field, uses a systems analysis approach that covers electrophysiology and neural imaging, both in animals and humans.

  • Haschek and Rousseaux's Handbook of Toxicologic Pathology Volume 5: Toxicologic Pathology of Organ Systems

    • 4th Edition
    • Wanda M Haschek + 3 more
    • English
    Haschek and Rousseaux's Handbook of Toxicologic Pathology, Fourth Edition, Volume Five: Toxicologic Pathology of Organ Systems is a key reference on the integration of structure and functional changes in tissues associated with the response to pharmaceuticals, chemicals, and biologics. This book continues coverage of Organ-Specific Toxicologic Pathology and major organ systems not covered in Volume Four, and has been completely revised, making it an essential part of the most authoritative reference on toxicologic pathology for pathologists, toxicologists, research scientists, and regulators studying and making decisions on drugs, biologics, medical devices, and other chemicals, including agrochemicals and environmental contaminants.

  • Biochar Ecotechnology for Sustainable Agriculture and Environment

    • 1st Edition
    • Abhay Kumar + 3 more
    • English
    Biochar Ecotechnology for Sustainable Agriculture and Environment summarizes current accomplishments in biochar ecotechnologies for enhancing agricultural production, encouraging sustainable waste management, and fostering a circular bioeconomy by advancing the pyrolysis process at both large-scale industrial and small-scale-local levels. Chapters in the book synthesize recent breakthroughs in biochar agro-ecotechnologies for increasing agricultural productivity and promoting circular bioeconomy by advancing the pyrolysis process and add mechanisms involved in biochar-fertilizer mediated in-soil biogeochemical cycle and nutrients retention, availability and their losses, soil-microbial responses, emission of greenhouse gases, and plant responses.Finally, this book aims to increase research understanding of nanotechnological breakthroughs in the production of biochar-based slow-release fertilizers, including their Nano characteristics involved in increasing fertilizer usage efficiency and managing chemical losses, for sustainable agriculture and the environment.

  • Patterns, Function and Application of Seed Microbiome

    Bacteria, Fungi and Viruses
    • 1st Edition
    • Mohammad Yaseen Mir + 3 more
    • English
    Patterns, Function and Application of Seed Microbiome: Bacteria, Fungi and Viruses presents the current understanding of seed and microbiota associations, emphasizing recent findings that highlight the latest insights into these interactions, and how they may ultimately influence plant ecology, health and productivity in both natural and agricultural systems. The development and dispersal of seeds and their transition to seedlings are among the most critical stages of the life cycle of plants and seed health is of crucial global importance for producing both quantity and high quality crops to feed world’s population. It is important for seeds to be produced that contain the best hybrid embryo so that it is free of diseases, includes beneficial endophytes and ensures a healthy start of a seedling. Focusing on the role of seed microbiota, their transmission and implications for producing healthier seeds as well as the relationship between the seed microbiome and primed plant resistance this book reveals the targeted use of the seed microbiome to enrich the soil biodiversity and its resilience and its resulting impact on plant health and yield. also explores the importance of nanotechnology in the development and production of crops for both improved plant production, and plant protection. It explores the different microbes that are vectored onto and within the seeds of both cultivated and non-cultivated plants, with an emphasis on the importance and roles of seed microbiomes in sustainable agriculture. It explains how to change seeds to increase microbiome vectoring; repairing damaged ones, and conserves seed microbiota. It also present seed microbiome roles for plant health and design effective microbiome engineering.

  • Medicinal Chemistry and Drug Development

    • 1st Edition
    • Gang Liu
    • English
    Medicinal Chemistry and Drug Development describes the key events and roles of medicinal chemistry in the discovery and development of lead compounds into drugs, including target identification, which is accomplished by using 30 case studies. This book outlines all the stages of drug development, including the discovery of active compounds, research on the pharmacologicalprope... of molecules, and confirmation of drug targets. The role of the case studies is to show the common factors in the successful development of drugs, thereby showing medicinal chemists how best to explore the scientific pathways when developing new drugs. This makes the book especially relevant for senior university students majoring in pharmaceutical sciences as well as graduate students and researchers.

  • Targeting Enzymes in the Brain

    • 1st Edition
    • Volume 102
    • English
    Targeting Enzymes in the Brain series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors.

  • Handbook of Immunoassay Technologies

    Approaches, Performances, and Applications
    • 2nd Edition
    • Sandeep K. Vashist + 1 more
    • English
    Handbook of Immunoassay Technologies: Approaches, Performances, and Applications, Second Edition unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays to the smartphone-based point-of-care formats. The book discusses how advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies that have paved the way for next-generation immunoassays.Revised and updated, the second edition of Handbook of Immunoassay Technologies: Approaches, Performances, and Applications covers all the relevant, timely, and important developments in the field. This edition offers new content on topics such as antibody production for immunodiagnostics, multiplex immunoassays, chemiluminescent immunoassays, immunoassays for newborn screening, and immunoassays of viruses like SARS-CoV-2, HIV, Ebola, and Hepatitis C. The addition of these new topics as well as up-to-date content make the second edition a valuable and comprehensive resource on immunoassays.

  • The Immunological Synapse Part C

    • 1st Edition
    • Volume 193
    • English
    The Immunological Synapse - Part C, Volume 193 in the Methods in Cell Biology series provides state-of-the-art and detailed methods for the study of the T cell, natural killer (NK) cell and B cell immunological synapses. Topics covered in this third volume include tau-STED microscopy for 3D-quantitative colocalization of lytic granule markers, image processing approaches for 3D-analysis of markers and for microtubule remodeling quantification at the immunological synapse, flow cytometry to analyze NK cell-target cell conjugation, imaging flow cytometry to quantify a range of different subcellular processes at the immunological synapse, imaging techniques aimed at quantitatively analyzing B cell immunological synapse formation, quantification of force-mediated antigen extraction in the B cell immune synapse using DNA-based tension sensors, measuring interaction forces between T lymphocytes and their target cells using live microscopy and laminar shear flow chambers, measuring interaction kinetics between T cells and their target tumor cells with optical tweezers, and gauging antigen recognition by human primary T-cells featuring orthotopically exchanged TCRs of choice. Additionally, this volume includes methods to isolate and characterize primary NK cells and enrich the KIR2DL1+ population, and to expand γδ T cells and evaluate their cytotoxicity.

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