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Books in Life sciences

  • Vaccinology and Methods in Vaccine Research

    • 1st Edition
    • March 10, 2022
    • Rebecca Ashfield + 3 more
    • English
    Vaccinology and Methods in Vaccine Research is a combination of cutting-edge methodologies, experimental approaches and literature reviews. The book covers all aspects of vaccine development, including basic immunology (focusing on the stimulation of adaptive immunity, which is required for vaccine efficacy), approaches to vaccine design and target validation, vaccine biomanufacturer and clinical development. Existing vaccinology resources are theoretical reference books, whereas this book provides a practical handbook for use in the research lab and classroom by those working in vaccinology and training others in the field. It is authored and edited by scientists actively engaged in vaccine research and development for day-to-day teaching/methodologi... advice.
  • Cancer Vaccines as Immunotherapy of Cancer

    • 1st Edition
    • March 4, 2022
    • Luigi Buonaguro + 1 more
    • English
    Cancer Vaccines as Immunotherapy of Cancer provides extensive and state-of-the-art information about the meaning, relevance and limitation of therapeutic cancer vaccines. It covers all the aspects involved in the vaccine research and development (identification of optimal target antigens, formulations, delivery strategies, adjuvants among others) as well as their use in combination with other immunomodulatory approaches. The book discusses topics such as identification of tumor associated and specific antigens, proteogenomic for identification of novel target tumor antigens, antigen-specific T cells, and Peptide and RNA based vaccines. Additionally, it covers oncolytic viruses for antigen delivery, cancer vaccine targeting viral antigens and combinatorial immunotherapy strategies. Written by leading experts worldwide, this is a valuable resource for cancer researchers, oncologists and members of biomedical field who wants to understand in depth the recent findings in the field of cancer vaccines.
  • Advanced Biosensors for Virus Detection

    Smart Diagnostics to Combat SARS-CoV-2
    • 1st Edition
    • March 4, 2022
    • Raju Khan + 3 more
    • English
    Advanced Biosensors for Virus Detection: Smart Diagnostics to Combat Against the SARS-CoV2 Pandemic covers the development of biosensor-based approaches for the diagnosis and prognosis of viral infections, specifically coronaviruses. The book discusses wide-ranging topics of available biosensor-based technologies and their application for early viral detection. Sections cover the emergence of SARS-CoV, MERS-CoV and SARS-CoV2, the global health response, the impact on affected populations, state-of-the art biomarkers, and risk factors. Specific focus is given to COVID-19, with coverage of genomic profiling, strain variation and the pathogenesis of SARS-CoV2. In addition, current therapeutics, nano-abled advancements and challenges in the detection of SARS-CoV2 and COVID-19 management are discussed, along with the role of nanomaterials in the development of biosensors and how biosensors can be scaled up for clinical applications and commercialization.
  • Osteosarcopenia

    • 1st Edition
    • March 4, 2022
    • Gustavo Duque + 1 more
    • English
    Falls, fractures, frailty, osteoporosis and sarcopenia are highly prevalent in older persons. While the concept of osteosarcopenia is new, it is a rapidly evolving and cross-disciplinary problem. Prevention and treatment are challenging and a combined therapeutic approach is needed. Osteosarcopenia provides evidence-based information on how to prevent and treat these conditions at multiple settings, including multiple illustrations, care pathways and tips to easily understand the pathophysiology, diagnostic methods and therapeutic approach to these conditions. This work evaluates the potential for a link between osteoporosis, sarcopenia and obesity.
  • Nanotherapeutics in Cancer Vaccination and Challenges

    • 1st Edition
    • March 3, 2022
    • Mahfoozur Rahman + 4 more
    • English
    Nanotherapeutics in Cancer Vaccination and Challenges consolidates the current research on cancer nanomedicine and therapeutic cancer vaccination to explore the most effective and promising avenues. The book covers cancer vaccines before exploring nanotherapeutics, DNA and mRNA vaccines in cancer treatment. Finally, it considers regulatory and industrial perspectives on cancer vaccination and nanotherapeutics. This resource will be useful for pharmaceutical scientists and researchers focused on biomedical engineering, chemical engineering, vaccine development, and cancer immunotherapy, along with advanced students in these subjects. Cancer is arguably the most complex and challenging disease known to mankind. Over the last two-decades, significant advancements have been made in new and novel concepts of cancer nanomedicines. Therapeutic cancer vaccines may be utilized to inhibit further growth of advanced cancers and/or relapsed tumors that are refractory to conventional therapies, such as surgery, radiation therapy and chemotherapy.
  • Hypogonadism, An Issue of Endocrinology and Metabolism Clinics of North America

    • 1st Edition
    • Volume 51-1
    • March 3, 2022
    • Channa Jayasena + 1 more
    • English
    In this issue of Endocrinology and Metabolism Clinics, guest editors Channa Jayasena and Shalender Bhasin bring their considerable expertise to the topic of Hypogonadism.
  • Plastic Pollution and Marine Conservation

    Approaches to Protect Biodiversity and Marine Life
    • 1st Edition
    • March 2, 2022
    • Giuseppe Bonanno + 1 more
    • English
    Plastic Pollution and Marine Conservation: Approaches to Protect Biodiversity and Marine Life provides comprehensive knowledge on the consequences of plastic waste in marine environments at different levels, ranging from ecological and biological, to social, economic and political. The book synthesizes historical information, gaps in current knowledge, and recent discoveries by illustrating the main stages that made plastics a global issue for ocean ecosystems and their wildlife. Written by international experts on marine pollution, marine biology, and management of environmental resources, this book explores the main topics of marine plastic pollution such as input quantification, polluting sources, ultimate fate, ecological consequences, and more. This an important resource for a wide audience, including marine conservationists, environmental managers, decision-makers, NGOs, private companies, and activists working to combat plastics in our seas and oceans.
  • Advances in Parasitology

    • 1st Edition
    • Volume 115
    • March 1, 2022
    • Russell Stothard + 1 more
    • English
    Advances in Parasitology, Volume 115, the latest release in this ongoing series, includes medical studies of parasites of major influence, along with reviews of more traditional areas, such as zoology, taxonomy and life history. Chapters in this update include Taking the strain out of onchocerciasis: a reanalysis of blindness and transmission data does not support the existence of a savanna blinding strain of onchocerciasis in West Africa, Enterocytozoon bieneusi of animals, Taenia solium taeniasis/cysticerco... Genomic analysis reveals predominant clonality and progressive evolution at all evolutionary scales in eukaryotic pathogens, HTLV-I and Strongyloides: the worm lurking beneath, and more.
  • The COVID-19 Pandemic

    A Global High-Tech Challenge at the Interface of Science, Politics, and Illusions
    • 1st Edition
    • March 1, 2022
    • Klaus Rose
    • English
    The COVID-19 Pandemic: A Global High-Tech Challenge at the Interface of Science, Politics, and Illusions discusses COVID-19 as the first pandemic in the Internet era and our current reality of continuous reports, news, and updates. Since its beginning, we were daily bombarded with news of what was happening around the world. There was no global political leadership. The United States was politically partially paralyzed. Russia and China hoped to gain diplomatic profile worldwide, but their vaccines are of limited efficacy, and trust in their clinical data is rightly low. The European Union did not order enough vaccines in time, but sued a large manufacturer for delivery delays. Now it is setting up yet another bureaucratic institution. At least the pharmaceutical or life science industry paved the way out, but is not enthusiastically praised for it. It would be too easy and superficial to blame mistakes of governments and leaders on stupidity. Idiocy exists, but we have to go deeper to understand how illusions and blind spots in today’s common perception and science, inertia, arrogance, conflicts of interest, competition of individuals, and states and institutions for public recognition have contributed to a multitude of flawed assessments and direct mistakes. Healthcare professionals and anyone interested in an in-depth understanding of humankind’s response to the COVID-19 challenge will not get around the key conclusions of this book.
  • Food Lipids

    Sources, Health Implications, and Future Trends
    • 1st Edition
    • February 26, 2022
    • Jose M. Lorenzo + 4 more
    • English
    Food Lipids: Sources, Health Implications, and Future Trends presents specific and updated details related to human health and emerging technologies to obtain valuable lipids and lipid analysis of food products. The book covers the most relevant topics of food lipids as main sources (animal, marine and vegetable) and their composition, the implication of different lipids in human health, the main degradative processes and analytical methods for quality. Written for nutrition researchers, food scientists, food chemists and chemical engineers, R&D managers, new product developers, and other professionals working in the food industry and academia, including students, this book is sure to be a welcomed reference. Lipids are vital for human nutrition as they provide energy to the biological processes of the body and contain substances with high importance as essential fatty acids or fat-soluble vitamins. Furthermore, lipids are responsible for many desirable characteristics of foods. However, in recent years consumers are increasingly aware of the diet-health relationship, especially the implication that some lipids exert in the development of different diseases.