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Books in Life sciences

  • The Chlamydomonas Sourcebook

    Volume 3: Cell Motility and Behavior
    • 3rd Edition
    • February 15, 2023
    • Susan Dutcher
    • English
    The Chlamydomonas Sourcebook, 3rd Edition Cell Motility and Behavior (Volume 3) The gold-standard reference introducin... this multidisciplinary science, fully revised and updated with the latest discoveries Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the third volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Cell Motility and Behavior has been fully revised and updated to include the wealth of new resources for the Chlamydomonas community. Reflecting the significant advancement in the understanding of the role of basal bodies and cilia play in human diseases, this volume employs quantitative proteomics and mass spectroscopy as well as cryo EM tomography and single particle cryo EM. Other topics such as current insights on mitosis and cytokinesis, ciliary assembly and motility, intraflagellar trans... and more help build an understanding of human diseases of the cilium. Cell Motility and Behavior presents the latest in research and best practices, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

  • The Chlamydomonas Sourcebook

    Volume 1: Introduction to Chlamydomonas and Its Laboratory Use
    • 3rd Edition
    • February 15, 2023
    • Ursula Goodenough
    • English
    The Chlamydomonas Sourcebook, 3rd Edition Introduction to Chlamydomonas and Its Laboratory Use (Volume 1) The gold-standard reference covering the basic biology of the Chlamydomonas alga and techniques for its laboratory analysis Originally published as the standalone Chlamydomonas Sourcebook, then expanded as the first volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Introduction to Chlamydomonas and Its Laboratory Use has been fully revised and updated to include a wealth of new resources for the Chlamydomonas community. Early chapters cover current understandings of its taxonomy, ultrastructure, cell and life cycles, and nuclear and organelle genomes, followed by technique-oriented chapters covering such topics as cell culture, mutagenesis, genetic analysis, construction of mutant libraries, and protein localization using immunofluorescence. This volume presents the latest in research and best practices, making it a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, and biochemistry; crop scientists; plant physiologists; and plant, molecular, and human disease biologists.

  • The Chlamydomonas Sourcebook

    Volume 2: Organellar and Metabolic Processes
    • 3rd Edition
    • February 15, 2023
    • Arthur Grossman + 1 more
    • English
    Originally published as the stand-alone Chlamydomonas Sourcebook, then expanded as the second volume in a three-part comprehensive gold-standard reference, The Chlamydomonas Sourcebook: Organellar and Metabolic Processes has been fully revised and updated to include a wealth of new knowledge and resources for the Chlamydomonas community. It details the tremendous progress recently made with respect to imaging the ultrastructure of cells, dissecting acclimation and biosynthetic responses, and elucidating molecular processes underlying the biology of organelles. In particular, this volume includes exciting new developments in the use of imaging technologies for examining supramolecular organization of the chloroplast, defining mechanisms of branched electron transfer pathways in photosynthesis, dissecting the organization of pyrenoids and CO2 concentration mechanisms, presenting the intricacies associated with acclimation to environmental conditions and providing new insights into dark metabolism and the network of fermentative metabolism. This book thus presents the latest advances in both the research and uses of new experimental approaches and technologies, making this a must-have resource for researchers and students working in plant science and photosynthesis, fertility, mammalian vision, aspects of human disease, acclimation to environmental change, and the biogenesis of cellular complexes.

  • Polysaccharide Degrading Biocatalysts

    • 1st Edition
    • February 15, 2023
    • Rosana Goldbeck + 1 more
    • English
    The transformation of polysaccharides into valuable compounds for health and industry requires the careful application of enzyme protocols and controlled biocatalysis. Polysaccharide-Degra... Biocatalysts provides a thorough grounding in these biocatalytic processes and their growing role in the depolymerization of polysaccharides, empowering researchers to discover and develop new enzyme-based approaches across pharmaceuticals, fuels, and food engineering. Here, over a dozen leading experts offer a close examination of structural polysaccharides, genetic modification of polysaccharides, polysaccharide degradation routes, pretreatments for enzymatic hydrolysis, hemicellulose-degrad... enzymes, biomass valorization processes, oligosaccharide production, and enzyme immobilization for the hydrolysis of polysaccharides, among other topics and related research protocols. A final chapter considers perspectives and challenges in an evolving, carbohydrate-based economy.

  • Atomic Force Microscopy for Nanoscale Biophysics

    From Single Molecules to Living Cells
    • 1st Edition
    • February 15, 2023
    • Mi Li
    • English
    Atomic Force Microscopy for Nanoscale Biophysics: From Single Molecules to Living Cells summarizes the applications of atomic force microscopy for the investigation of biomolecules and cells. The book discusses the methodology of AFM-based biomedical detection, diverse biological systems, and the combination of AFM with other complementary techniques. These state-of-the-art chapters empower researchers to address biological issues through the application of atomic force microscopy. Atomic force microscopy (AFM) is a unique, multifunctional tool for investigating the structures and properties of living biological systems under aqueous conditions with unprecedented spatiotemporal resolution.

  • Precision Medicine in Neurodegenerative Disorders

    Part I
    • 1st Edition
    • Volume 192
    • February 14, 2023
    • English
    Precision Medicine in Neurodegenerative Disorders, Part One, Volume 192 in the Handbook of Clinical Neurology deals with the "Why" in the approach to slow the progression of accelerated brain aging. This volume is intended to provide a scholarly background on the framework, basic science and conceptual pitfalls related to disease-modifying efforts in Parkinson's, Alzheimer's and other neurodegenerative disorders. Among topics covered are different models of precision medicine, the lumping-versus-split... tension in biomarker development and therapeutics, and the rationale for replacing the convergence of the prevailing autopsy-based nosology of neurodegenerative diseases with the divergence of a systems biology approach to human diseases. Specific chapters are dedicated to the promise of genetic subtypes and the lessons in disease modification offered by the fields of oncology and cystic fibrosis that can be adapted to the field of neurodegeneration. Matching a biology-correcting therapy with those biologically suitable to benefit from such therapy represents the vision and mission of precision medicine, the highest level of personalized medicine.

  • Proteomics

    A Promising Approach for Cancer Research
    • 1st Edition
    • February 14, 2023
    • Shafat Ali + 2 more
    • English
    Proteomics: A Promising Approach for Cancer Research provides an updated overview of scientific knowledge, achievements and findings in the field of cancer proteomics. The book discusses topics such as the use of proteomics in cancer biology and drug discovery, its role in surgical oncology, applications of mass spectrometry, target proteomics, single-cell proteomics, and next-generation proteomics. In addition, it discusses proteomics and phosphor-proteomics in cancer precision medicine; translation of proteomics research into clinical application; and challenges and future developments of the field. This will be a valuable resource for cancer researchers, oncologists, graduate students, and members of biomedical field who are interested in the potential of proteomics in cancer research and treatment. The field of cancer proteomics is very dynamic, with emerging trends related to clinical solutions developed in recent years, therefore this book's content helps readers get up-to-speed on the topic to easily apply learnings into their research or clinical practice.

  • Sex and Cohabitation Among Early Humans

    Anthropological and Genetic Evidence for Interbreeding Among Early Humans
    • 1st Edition
    • February 14, 2023
    • Rene J. Herrera + 1 more
    • English
    Sex and Cohabitation Among Early Humans: Anthropological and Genetic Evidence for Interbreeding Among Early Humans explores the available information regarding interbreeding among different ancestral human species. In addition, it reviews evidence in support of cohabitation as well as cultural and technological interactions and exchanges among early humans, particularly Neanderthal-sapiens interactions. The fields of archaeology, anthropology, genetics, linguistics and molecular evolution have provided a wealth of information on the complex processes involved in human evolution. The book will help readers will develop knowledge on the complexity and multiplicity of hominins, including Homo heidelbergensis, Homo sapiens, and Homo floresiensis. Moreover, the book will help them reach a greater understanding of major topics, such as introgression, migration from Africa, the origin, development and extinction of Neanderthals, interbreeding between Neanderthals and humans, and trait continuity.

  • Computational Modeling of Infectious Disease

    With Applications in Python
    • 1st Edition
    • February 14, 2023
    • Chris von Csefalvay
    • English
    Computational Modeling of Infectious Disease: With Applications in Python provides an illustrated compendium of tools and tactics for analyzing infectious diseases using cutting-edge computational methods. From simple S(E)IR models, and through time series analysis and geospatial models, this book is both a guided tour through the computational analysis of infectious diseases and a quick-reference manual. Chapters are accompanied by extensive practical examples in Python, illustrating applications from start to finish. This book is designed for researchers and practicing infectious disease forecasters, modelers, data scientists, and those who wish to learn more about analysis of infectious disease processes in the real world.

  • Security and Privacy Issues in Internet of Medical Things

    • 1st Edition
    • February 14, 2023
    • Rajkumar Buyya + 4 more
    • English
    Security and Privacy Issues in Internet of Medical Things addresses the security challenges faced by healthcare providers and patients. As IoMT devices are vulnerable to cyberattacks, and a security breach through IoMT devices may act as a pathway for hackers to enter hospital networks, the book covers a very timely topic. The incorporation of blockchain in the healthcare environment has given birth to the Internet of Medical Things (IoMT), which consists of a collection of healthcare systems that espouse groundbreaking technologies. Systems consist of inter-linked sensors, wearable technology devices and clinical frameworks that perform explicit, secure machine-to-machine and cloud platform communications. The significance of IoMT in the field of healthcare is undoubtedly a win-win situation for patients through technology enhancements and a collection of analytics that helps in better diagnosis and treatment. Due to higher accuracy levels, IoMT devices are more reliable in reporting and data tracking and help avoid human errors and incorrect reporting.

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