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Books in Life sciences

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  • Antimicrobial Peptides

    Challenges and Future Perspectives
    • 1st Edition
    • K. Sreejith + 1 more
    • English
    Antimicrobial Peptides: Challenges and Future Perspectives covers the latest developments about antimicrobial peptides in the scenario of drug resistance. The book is divided into 16 chapters arranged in sequence and preceded by chapters on historical developments and their role as regulatory molecules in innate defense mechanism. Emphasis is given to purification techniques and characterization suitable for interdisciplinary research. Chapters provide an inventory of various antimicrobial peptides, from a diverse array of organisms such as bacteria, fungi, insects, amphibians, plants and mammals. A section on marine ecosystem broadens readers understanding on marine based antimicrobial peptides. Additional sections provide an informative overview on peptides with antiviral properties and those targeting multi-drug resistant bacteria. Recent reports and mechanism on resistance against antimicrobial peptides are also provided, along with key insights into the challenges and future perspectives of peptide drug development.

  • Bidirectional Gene Promoters

    Transcription system and chromosomal structure
    • 1st Edition
    • Fumiaki Uchiumi
    • English
    Recent studies in human genetics and in silico analyses have revealed that a number of genes are head-head orientated with other genes or non-coding RNAs. The expression of regulatory element-containing 5’-upstream regions of gene pairs are referred to as bi-directional promoters and are thought to have a key role in biological regulatory mechanisms. For example, tumor suppressor protein-encoding TP53 and BRCA1 genes are head-head bound with WRAP53 and NBR2, respectively. DNA-repair factor-encoding ATM and PRKDC (DNA-PKcs) genes have bidirectional partner NPAT and MCM4, respectively. Surveillance of the human DNA database has revealed that the numbers of DNA repair/mitochondrial function/immune response-associated genes are bound with other genes that are transcribed to opposite direction. The observations may encourage us to investigate in the molecular mechanisms how DNA repair/mitochondrial function/immune response-associated genes are regulated by bidirectional promoters. Not only protein-coding genes, but also quite a few ncRNAs, which play important roles in various cellular events, are transcribed under the regulation of the bidirectional promoters. More importantly, we know that dysregulation in the promoter activity and transcription initiation of genes might cause human diseases.

  • Central Nervous System Infections, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 33-1
    • Tchoyoson Lim
    • English
    In this issue of Neuroimaging Clinics, guest editor Dr. Tchoyoson Lim Choie Cheio brings his considerable expertise to the topic of Central Nervous System Infections. Infections can involve any part of the CNS and often, multiple parts of the CNS are involved at the same time. The imaging surrounding them is constantly evolving, and in this issue, key international experts provide a thorough update of the imaging of these common and pervasive infections.

  • RNA Methodologies

    A Laboratory Guide for Isolation and Characterization
    • 6th Edition
    • Robert E. Farrell Jr.
    • English
    RNA Methodologies: A Laboratory Guide for Isolation and Characterization, Sixth Edition provides the most up-to-date ribonucleic acid lab techniques for seasoned scientists and graduate students alike. This edition features new material on RNA sequencing, RNA in Situ Hybridization, non-coding RNAs, computational RNA biology, transcriptomes and bioinformatics, along with the latest advances in methods and protocols across the field of RNA investigation. As a leader in the field, Dr. Farrell provides a wealth of knowledge on the topic of RNA biology while also giving readers helpful hints and troubleshooting techniques from his own personal experience in this subject area. This book presents the essential knowledge and techniques to use when working with RNA for the experienced practitioner, while also aiding the beginner in fully understanding this important branch of molecular biology.

  • Emerging Thermal Processes in the Food Industry

    Unit Operations and Processing Equipment in the Food Industry
    • 1st Edition
    • Seid Mahdi Jafari
    • English
    Emerging Thermal Processes in the Food Industry, a volume in the Unit Operations and Processing Equipment in the Food Industry series, explains the processing operations and equipment necessary for thermal processing, including infrared heating, microwave processing, sonication, UV processing, ohmic heating and dielectric processing. These processes and unit operations are very important in terms of achieving favorable sensory properties and energy usage. Chapters emphasize basic texts relating to experimental, theoretical, computational and/or applications of food engineering principles and relevant processing equipment for emerging thermal unit operations. Written by experts in the field of food engineering in a simple and dynamic way, this book targets industrial engineers working in the field of food processing and within food factories to make them more familiar with food processing operations and equipment.

  • QTL Mapping in Crop Improvement

    Present Progress and Future Perspectives
    • 1st Edition
    • Shabir Hussain Wani + 2 more
    • English
    QTL Mapping in Crop Improvement: Present Progress and Future Perspectives presents advancements in QTL breeding for biotic and abiotic stresses and nutritional improvement in a range of crop plants. The book presents a roadmap for future breeding for resilience to various stresses and improvement in nutritional quality. Crops such as rice, wheat, maize, soybeans, common bean, and pigeon pea are the major staple crops consumed globally, hence fulfilling the nutritional requirements of global populations, particularly in the under-developed world, is extremely important. Sections cover the challenges facing maximized production of these crops, including diseases, insect damage, drought, heat, salinity and mineral toxicity. Covering globally important crops including maize, wheat, rice, barley, soybean, common bean and pigeon pea, this book will be an important reference for those working in agriculture and crop improvement.

  • Microbial Endophytes and Plant Growth

    Beneficial Interactions and Applications
    • 1st Edition
    • Manoj Kumar Solanki + 3 more
    • English
    Microbial Endophytes and Plant Growth: Beneficial Interactions and Applications explains how modern molecular tools can unlock the plant's microbial network, building the bridge between plant and environment. Chapters describe the usefulness of the endophytic microbiome of different crops, including cereals, vegetables and horticulture, and delve into the latest research surrounding the applications of plant-microbe interactions in improving plant growth. Other topics discussed include root endophytes and their role in plant fitness, seed associated endophytes and their functions, and microbial endophytes and nanotechnology. This is a one-stop resource for scientists wanting access to the latest research in plant microbiology. The book also provides advanced techniques for using multi-omics approaches to study plant-microbe interactions, providing readers with a practical approach.

  • Mathematical Approaches to Molecular Structural Biology

    • 1st Edition
    • Subrata Pal
    • English
    Mathematical Approaches to Molecular Structural Biology offers a comprehensive overview of the mathematical foundations behind the study of biomolecular structure. Initial chapters provide an introduction to the mathematics associated with the study of molecular structure, such as vector spaces and matrices, linear systems, matrix decomposition, vector calculus, probability and statistics. The book then moves on to more advanced areas of molecular structural biology based on the mathematical concepts discussed in earlier chapters. Here, key methods such as X-ray crystallography and cryo-electron microscopy are explored, in addition to biomolecular structure dynamics within the context of mathematics and physics. This book equips readers with an understanding of the fundamental principles behind structural biology, providing researchers with a strong groundwork for further investigation in both this and related fields.

  • Advances in Immunology

    • 1st Edition
    • Volume 156
    • English
    Advances in Immunology, Volume 156, the latest release in a long-established and highly respected publication, presents current developments and comprehensive reviews in immunology, with this volume covering self-referential immune recognition through C-type lectin receptors, genetic susceptibility to autoimmunity, activation and regulation of the cGAS-STING pathway and the implications of IL-15 trans-presentation on the immune response.

  • Food Quality Analysis

    Applications of Analytical Methods Coupled With Artificial Intelligence
    • 1st Edition
    • Ashutosh Kumar Shukla
    • English
    Food Quality Analysis: Applications of Analytical Methods Coupled With Artificial Intelligence provides different spectroscopic techniques and their application to food quality analysis, with the unique approach of adding multivariate analysis as well as artificial intelligence applications. It also brings chromatographic methods for the analysis of a wide range of food items including wheat flours, oils and fats. Written by a team of interdisciplinary experts, this is a valuable resource for researchers and personnel involved in food industries.　　

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