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Books in Life sciences

  • Rigor and Reproducibility in Genetics and Genomics

    Peer-reviewed, Published, Cited
    • 1st Edition
    • English
    Rigor and Reproducibility in Genetics and Genomics: Peer-reviewed, Published, Cited provides a full methodological and statistical overview for researchers, clinicians, students, and post-doctoral fellows conducting genetic and genomic research. Here, active geneticists, clinicians, and bioinformaticists offer practical solutions for a variety of challenges associated with several modern approaches in genetics and genomics, including genotyping, gene expression analysis, epigenetic analysis, GWAS, EWAS, genomic sequencing, and gene editing. Emphasis is placed on rigor and reproducibility throughout, with each section containing laboratory case-studies and classroom activities covering step-by-step protocols, best practices, and common pitfalls. Specific genetic and genomic technologies discussed include microarray analysis, DNA-seq, RNA-seq, Chip-Seq, methyl-seq, CRISPR gene editing, and CRISPR-based genetic analysis. Training exercises, supporting data, and in-depth discussions of rigor, reproducibility, and ethics in research together deliver a solid foundation in research standards for the next generation of genetic and genomic scientists.

  • Drug-delivery systems of phytochemicals as therapeutic strategies in cancer therapy

    • 1st Edition
    • Akhileshwar Kumar Srivastava + 2 more
    • English
    Drug-delivery Systems of Phytochemicals as Therapeutic Strategies in Cancer Therapy elucidates the importance of various phytochemicals in cancer therapy and explains various routes/methods to deliver phytochemicals for overcoming the problems associated with delivery systems in cancer treatment. Several nanotechnological methods are presented to enhance drug solubility, sustainability, bioavailability, and gastrointestinal permeability of these phytochemicals. Current understanding of the relevant information presented on therapeutic strategies in cancer therapy fulfils the requirements of oncologists, molecular biologists, pharmacologist and related researchers who want to work in the areas of drug development targeting phytochemicals for cancer therapy.

  • Entrepreneurship with Microorganisms

    • 1st Edition
    • A. C. Shukla
    • English
    Entrepreneurship with Microorganisms explains both the basic science and applications of microbiology and bio-resource technology, shining a special emphasis on its entrepreneurial applications. By focusing on basic principles, current research, and global trends, this comprehensive book provides a critical resource and serves as a complete one-stop source for undergraduate and graduates in microbiology, food, agricultural science, medical science, and industrial microbiology biotechnology. In addition, this book will be helpful in the creation of economic (commercial) value of the microorganism(s) based products and technologies as well as opportunities for new jobs at the global level.

  • Biochemistry of Collagens, Laminins and Elastin

    Structure, Function and Biomarkers
    • 3rd Edition
    • Morten Karsdal
    • English
    Biochemistry of Collagens, Laminins, and Elastin: Structure, Function and Biomarkers, Third Edition provides current data on key structural proteins (collagens, laminins, and elastin), reviews on how these molecules affect pathologies, and information on how selected modifications of these proteins can result in altered signaling properties of the original extracellular matrix (ECM). Further, it discusses the novel concept that an increasing number of components of the extracellular matrix harbor cryptic signaling functions with ties to endocrine function, and how this knowledge may be used to modulate various pathologies, including fibrotic disease. This new edition has been expanded and revised to incorporate recent research advances. Several new chapters explore a range of chronic diseases in which the ECM and collagens, laminin and elastin are central players in disease modulation, including new chapters on lung, skin and intestinal disease, as well as cancers. The new edition also considers emerging analytical technologies that can detect biomarkers of ECM degradation, with discussion of protein quantification and detecting aging of collagens.

  • Starch Based Nanomaterials for Food Packaging

    Perspectives and Future Prospectus
    • 1st Edition
    • Gulzar Ahmad Nayik + 1 more
    • English
    Starch-Based Nanomaterials for Food Packaging: Perspectives and Future Prospectus presents the properties and sources of starch- based nanomaterials, new perspectives, safety aspects, applications and future trends. The book's chapters cover nanostructured materials, polysaccharide based bionanocomposites, starch based nanofibers, starch food packaging applications, nano gold imprinted starch bio nanocomposites, cereal starch-based nanoparticles, and edible packaging reinforced with starch-based nanomaterials. This is a complete resource to food industrialists who deal directly with food packaging and fruit and vegetable preservation.

  • The Enzymes

    • 1st Edition
    • Volume 54
    • English
    The Enzymes, Volume 54 highlights new advances in enzymes, with new chapters on a variety of topics, including the History of The Enzymes, Impact of The Enzymes in chronicling biochemical processes and pathways, Metabolism and Catalysis, Mitochondrial ATP synthase, The respiratory chain, A century of mitochondrial research, Five decades of metalloenzymology, Mechanisms of catalysis, Mitochondrial fatty acid synthesis and associated processes, Signaling, MAPK cascades: Origins, mechanisms and current status, Sphingolipids: From structural components to signaling hubs, Protein Homeostasis and Hydrolysis, Mitochondrial AAA+ proteases, Hsp70 and JDP proteins: structure-function perspective on molecular chaperone activity. Other sections cover DNA Replication and Repair, Structure-function studies of DNA replication proteins, and Helicases required for nucleotide excision repair.

  • The COVID-19 Disruption and the Global Health Challenge

    • 1st Edition
    • Vincenzo Atella + 1 more
    • English
    The COVID-19 pandemic represents an important watershed for modern society. The world will never be the same. Almost all economic and social activities need to be reviewed, rethought, and adapted to the new context. The COVID-19 Disruption and the Global Health Challenge explains a complex phenomenon that has left doubts and uncertainties among the many who want to understand.The book fills some of these gaps by providing answers to a series of questions including why the epidemic originated, how it spread, how it was managed, how long we will have to live with it, what effects did it have on the economy, who will be most affected, how the new world will change us, and how our way of seeing the world will change. Lastly, the book proposes some solutions to prevent and be more prepared to the recurrence of such events as well as to manage them more effectively.

  • Good and Bad Testosterone

    • 1st Edition
    • Ilpo Huhtaniemi
    • English
    Good and Bad Testosterone is a unique reference to understand and learn about the biology and psychophysical aspects of this hormone.Unlike most other hormones, testosterone regulates not only the biological functions of the body but also many psychological functions. This wide spectrum of effects, influencing nearly all biological and behavioral features of a males, makes testosterone particularly interesting.This book takes a historical approach to understanding testosterone. It provides is a comprehensive description of the functions of testosterone and its role in determining the biological, medical, psychological, behavioral, and cultural features of the male sex/gender and the male/female differences. Sex/gender issues are of great interest for a wide readership, including the general public and experts from various disciplines.

  • Genomics in the Clinic

    A Practical Guide to Genetic Testing, Evaluation, and Counseling
    • 1st Edition
    • Antonie D. Kline + 1 more
    • English
    **Selected for 2025 Doody’s Core Titles® in Clinical Genetics**Genomics in the Clinic: A Practical Guide to Genetic Testing, Evaluation, and Counseling illustrates the current scope of the practice of genetics for healthcare professionals, so they can understand principles applicable to genetic testing and consultation. Written by an authoritative well-balanced team, including experienced clinical geneticists, genetic counselors, and medical subspecialists, this book adopts an accessible, easy-to-follow format. Sections are dedicated to basic genetic principles; clinical genetic and genomic testing; prenatal, clinical and cancer genetic diagnosis and counseling; and ethical and social implications in genomic medicine. Over 100 illustrative cases examine a range of prenatal, pediatric and adult genetic conditions and testing, putting these concepts and approaches into practice. Genomics in the Clinic: A Practical Guide to Genetic Testing, Evaluation, and Counseling is important for primary care providers, as patient care evolves in the current genomic-influenced world of precision medicine.

  • The Science of Human Milk

    • 1st Edition
    • Josef Neu
    • English
    The Science of Human Milk offers readily understandable, scientifically sound information related to the compositional features of human milk at different stages of lactation. The book also debunks many myths about human milk and provides an analysis of the differences in human milk and baby formulas, offering suggestions for how the latter can be improved. The correlation between human milk composition and infant physiology and metabolism, growth, development, health and disease is explored in detail, placing emphasis on preterm infants. In addition, the dynamic nature of human milk, including its microbes, immunology, metabolites, cell components and epigenetically active molecules are covered. Written for researchers working in nutrition and neonatology, as well as health care professionals working in related fields, this book is sure to be a welcomed reference.

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