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Elsevier

Books in Life sciences

  • Gametogenesis

    • 1st Edition
    • Volume 102
    • English
    This new volume of Current Topics in Developmental Biology covers the area of gametogenesis, with contributions from an international board of authors. The chapters provide a comprehensive set of reviews covering such topics as germline stem cells, signaling modalities during oogenesis in mammals, and genomic imprinting as a parental effect established in mammalian germ cells.

  • Fluorescence Fluctuation Spectroscopy (FFS) Part B

    • 1st Edition
    • Volume 519
    • English
    This new volume of Methods in Enzymology continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume covers fluorescence fluctuation spectroscopy and includes chapters on such topics as Förster resonance energy transfer (fret) with fluctuation algorithms, protein corona on nanoparticles by FCS, and FFS approaches to the study of receptors in live cells.

  • Encyclopedia of Human Nutrition

    • 3rd Edition
    • English
    The role of nutrition in improving quality of life and combating disease is undeniable — and researchers from different disciplines are bringing their perspectives to bear on this fundamental topic. The 4-volume Encyclopedia of Human Nutrition, Third Edition, is a thorough revision of the previous award-winning version and reflects the scientific advances in the field of human nutrition. It presents the latest understanding on a wide range of nutrition-related topics including food safety, weight management, vitamins, bioengineering of foods, plant based diet and raw foods among others. New articles on organic food, biofortification, nutritional labeling and the effect of religious customs on diet, among many others, reflect the dedication to currency in this revision. It not only contains the most current and thorough information available on the topic, but also contains broader cross-referencing on emerging opportunities for potential treatment and prevention of diseases.An ideal starting point for scientific research, Encyclopedia of Human Nutrition, Third Edition, continues to provide authoritative information in an accessible format, making this complex discipline available to readers at both the professional and non-professional level.

  • Plastic Films in Food Packaging

    Materials, Technology and Applications
    • 1st Edition
    • Sina Ebnesajjad
    • English
    The value of the groceries purchases in the USA is over $500 billion annually, most of which is accounted for by packaged foods. Plastic packaging of foods is not only ubiquitous in developed economies, but increasingly commonplace in the developing world, where plastic packaging is instrumental in decreasing the proportion of the food supply lost to spoilage. This new handbook is a combination of new material and updated chapters, chosen by Dr. Sina Ebnesajjad, from recently published books on this subject. Plastic Films in Food Packaging offers a practical handbook for engineers, scientists and managers working in the food packaging industry, providing a tailor-made package of science and engineering fundamentals, best practice techniques and guidance on new and emerging technologies. By covering materials, design, packaging processes, machinery and waste management together in one book, the authors enable the reader to take a lifecycle approach to food packaging. The Handbook addresses questions related to film grades, types of packages for different types of foods, packaging technologies, machinery and waste management. Additionally the book provides a review of new and emerging technologies. Two chapters cover the development of barrier films for food packaging and the regulatory and safety aspects of food packaging.

  • Genomics of Cyanobacteria

    • 1st Edition
    • Volume 65
    • English
    Advances in Botanical Research publishes in-depth and up-to-date reviews on a wide range of topics in plant sciences. The series features a wide range of reviews by recognized experts on all aspects of plant genetics, biochemistry, cell biology, molecular biology, physiology and ecology. This thematic volume features reviews on The Genomics of Cyanobacteria.

  • Insulin Therapy, An Issue of Endocrinology and Metabolism Clinics

    • 1st Edition
    • Volume 41-1
    • John L. Leahy + 1 more
    • English
    This issue of Endocrinology Clinics brings the reader up do date on the current standards and important advances in insulin therapy. The following clinical topics are discussed: types of insulins, including new insulins; goals of therapy; pathophysiology of, and insulin treatment in type1 and type 2 diabetes mellitus; pumps and glucose sensors; alternative insulin delivery; patient and provider insulin resistance; inpatient insulin therapy; insulin therapy in pregnancy; and pediatric insulin therapy.

  • Atlas of Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 1st Edition
    • Faramarz Naeim
    • English
    As the definitive diagnostic atlas of the diseases of the hematopoietic system, the Atlas of Hematopathology appeals to a wide range of people who are being trained in a variety of medical fields or practicing as non-hematopathologis... and therefore, are looking for a book which can provide information in a clear, focused format, with no excessive text or details. The atlas offers effective guidance in evaluating specimens from the lymph nodes, bone marrow, spleen, and peripheral blood, enabling clinicians to deliver more accurate and actionable pathology reports. Practicing physicians and those in pathology and hematology training also gain a better understanding of the nature of hematologic disorders and improve their diagnostic skills along the way. Taking a unique multi-disciplinary approach, the book covers conventional histopathology and cytopathology, as well as all important complementary diagnostic tests, such as immunophenotyping (immunohistochemical stains and flow cytometry), karyotyping, FISH and DNA/molecular studies. It offers concise textual and extensive visual coverage of both neoplastic and non-neoplastic hematology disorders, with the neoplastic hematology sections presented according to the most recent WHO classifications. There is also an introduction to the normal structures of hematopoietic tissues and the various multidisciplinary techniques. The atlas contains more than 900 high-quality color images that mirror the findings that fellows and clinicians encounter in practice. It provides information in a quick, simple and user-friendly manner, attracting those who are in training or are not considered experts in the field. Residents, fellows, practicing clinicians, and researchers in pathology, hematology, hematology/oncology, as well as graduate students in pathology and other clinicians workings in clinical hematology laboratories will all find it useful.

  • The Epidemiology of Plasmodium Vivax: History, Hiatus and Hubris

    • 1st Edition
    • Volume 80
    • English
    First published in 1963, Advances in Parasitology contains comprehensive and up-to-date reviews in all areas of interest in contemporary parasitology. Advances in Parasitology includes medical studies on parasites of major influence, such as Plasmodium falciparum and trypanosomes. The series also contains reviews of more traditional areas, such as zoology, taxonomy, and life history, which shape current thinking and applications. Eclectic volumes are supplemented by thematic volumes on various topics, including control of human parasitic diseases and global mapping of infectious diseases. The 2010 impact factor is1.683.

  • Nutritional Management of Renal Disease

    • 3rd Edition
    • Joel D. Kopple + 2 more
    • English
    This translational text offers in-depth reviews of the metabolic and nutritional disorders that are prevalent in patients with renal disease. Chapter topics address the growing epidemic of obesity and metabolic syndrome. Each chapter integrates basic and clinical approaches, from cell biology and genetics to diagnosis, patient management and treatment. Chapters in sections 4-7 include new illustrative case reports, and all chapters emphasize key concepts with chapter-ending summaries. New features also include the latest National Kidney Foundation Clinical Practice Guidelines on Nutrition in Chronic Renal Failure, the most recent scientific discoveries and the latest techniques for assessing nutritional status in renal disease, and literature reviews on patients who receive continuous veno-venous hemofiltration with or without dialysis.

  • NMR Metabolomics in Cancer Research

    • 1st Edition
    • Miroslava Čuperlović-Culf
    • English
    The application of nuclear magnetic resonance (NMR) metabolomics in cancer research requires an understanding of the many possibilities that NMR metabolomics can offer, as well as of the specific characteristics of the cancer metabolic phenotype and the open questions in cancer research. NMR metabolomics in cancer research presents a detailed account of the NMR spectroscopy methods applied to metabolomics mixture analysis along with a discussion of their advantages and disadvantages. Following an overview of the potential use of NMR metabolomics in cancer research, the book begins with an examination of the cancer metabolic phenotype and experimental methodology, before moving on to cover data pre-processing and data analysis. Chapters in the latter part of the book look at dynamic metabolic profiling, biomarker discovery, and the application of NMR metabolomics for different types of cancer, before a concluding chapter discusses future perspectives in the field.

  • Nutrigenetics

    Applying the Science of Personal Nutrition
    • 1st Edition
    • Martin Kohlmeier
    • English
    Nutrigenetics: Applying the Science of Personal Nutrition provides a fully referenced, readable guide to understanding the rationale and importance of nutrigenetic applications and explains why single nutrition recommendations will not fit everybody or even a majority of modern humans. This books explains how genetic variation shapes individual nutrition requirements and sensitivities, presents questions to ask about reported gene-nutrient interactions, and what needs to be done before putting nutrigenetic tests to practical use. This book blends key concepts from the fields of genetics, biochemistry, epidemiology, public health, and clinical medicine to give a rich perspective on the genetically diverse nutritional needs and sensitivities of individuals in health and disease. A steadily increasing number of people order genetic tests to find out what they should eat for better health, well being and performance, and an even greater number asks their healthcare providers about such tests. Most of the currently offered tests are not grounded in current knowledge, often absurdly so, but few professionals can explain why they are misguided. On the other hand, there are more evidence-supported genetic variants that can guide nutrition decisions, but again most healthcare providers know little about them, much less use them in their daily practice. There is a great need for a solidly evidence-based yet accessible book that explains the science of nutrigenetics and provides the tools to evaluate new nutrigenetic tests.

  • Side Effects of Drugs Annual

    A worldwide yearly survey of new data in adverse drug reactions
    • 1st Edition
    • Volume 34
    • Jeffrey K Aronson
    • English
    The Side Effects of Drugs Annual was first published in 1977. It has been continually published since then as a yearly update to the voluminous encyclopedia, Meyler's Side Effects of Drugs. Each new Annual continues to provide clinicians and medical investigators with a reliable and critical yearly survey of new data and trends in the area of adverse drug reactions and interactions. An international team of specialists has contributed to the informative Annual by critically interpreting it and by pointing to whatever is misleading.

  • Microfluidic Cell Culture Systems

    • 1st Edition
    • Christopher Bettinger + 2 more
    • English
    The fields of microfluidics and BioMEMS are significantly impacting cell biology research and applications through the application of engineering solutions to human disease and health problems. The dimensions of microfluidic channels are well suited to the physical scale of biological cells, and the many advantages of microfluidics make it an attractive platform for new techniques in biology. This new professional reference applies the techniques of microsystems to cell culture applications. The authors provide a thoroughly practical guide to the principles of microfluidic device design and operation and their application to cell culture techniques. The resulting book is crammed with strategies and techniques that can be immediately deployed in the lab. Equally, the insights into cell culture applications will provide those involved in traditional microfluidics and BioMEMS with an understanding of the specific demands and opportunities presented by biological applications. The goal is to guide new and interested researchers and technology developers to the important areas and state-of-the-practic... strategies that will enhance the efficiency and value of their technologies, devices and biomedical products.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part II
    • 1st Edition
    • Volume 201
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on Functional Neural Transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Axon Growth and Regeneration: Part 2

    • 1st Edition
    • Volume 106
    • English
    Leading authors review state-of-the-art in their field of investigation and provide their views and perspectives for future research. Chapters are extensively referenced to provide readers with a comprehensive list of resources on the topics covered. All chapters include comprehensive background information and are written in a clear form that is also accessible to the non-specialist

  • Axon Growth and Regeneration: Part 1

    • 1st Edition
    • Volume 105
    • English
    Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research. This volume reviews existing theories and current research surrounding Axon Growth and Regeneration.

  • Emerging Horizons in Neuromodulation

    New Frontiers in Brain and Spine Stimulation
    • 1st Edition
    • Volume 107
    • English
    This issue of International Review of Neurobiology brings together cutting-edge research on neuromodulation. It reviews current knowledge and understanding, provides a starting point for researchers and practitioners entering the field, and builds a platform for further research and discovery.

  • Agricultural Sustainability

    Progress and Prospects in Crop Research
    • 1st Edition
    • Gurbir Bhullar + 1 more
    • English
    Collaboratively written by top international experts and established scientists in various fields of agricultural research, this book focuses on the state of food production and sustainability; the problems with degradation of valuable sources of land, water, and air and their effects on food crops; the increasing demand of food resources; and the challenges of food security worldwide. The book provides cutting edge scientific tools and methods of research as well as solid background information that is accessible for those who have a strong interest in agricultural research and development and want to learn more on the challenges facing the global agricultural production systems.

  • Head and Neck Cancer, An Issue of Neuroimaging Clinics

    • 1st Edition
    • Volume 23-1
    • Patricia A. Hudgins + 1 more
    • English
    This issue reviews the state of the art in imaging head and neck cancer. Articles cover topics on Rationale for Staging by Imaging; Oral Cavity Cancer; Oropharynx; Nasopharyngeal Carcinoma; Pitfalls in Staging Squamous Cell Carcinoma of the Hypopharynx; Larynx; Major Salivary Glands; Thyroid Cancer; Lymph Nodes; Image-Guided Tissue Sampling; and Surgical Perspective.

  • Functional Neural Transplantation III

    Primary and Stem Cell Therapies for Brain Repair, Part I
    • 1st Edition
    • Volume 200
    • English
    This issue of Progress in Brain Research is split over 2 volumes, bringing together cutting-edge research on functional neural transplantation. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Co-Transport Systems

    • 1st Edition
    • Volume 70
    • English
    Current Topics in Membranes is targeted towards scientists and researchers in biochemistry and molecular and cellular biology, providing the necessary membrane research to assist them in discovering the current state of a particular field and in learning where that field is heading. In this volume, researchers are encouraged to fully explore topics and research related to co-transport systems. The authors and editors associated with the Current Topics in Membranes series are recognized as world-renowned scientists in their respective fields, making CTM one of the premier serials on membranes.

  • Platelets

    • 3rd Edition
    • Alan D. Michelson
    • English
    Platelets - winner of a 2013 Highly Commended BMA Medical Book Award for Internal Medicine - is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.

  • Workbook for Pharmacology for Pharmacy Technicians

    • 2nd Edition
    • Kathy Moscou + 1 more
    • English
    Specially designed to parallel the material in Pharmacology for Pharmacy Technicians, 2nd Edition, this helpful workbook provides in-depth study and review of the ASHP content requirements for pharmacology and anatomy and physiology. Its user-friendly format and engaging learning exercises help you understand both basic and advanced pharmacologic concepts. Practical activities allow you to apply your knowledge to real-world scenarios.

  • Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation

    Models in Discovery and Translation
    • 1st Edition
    • Gerard Socie + 1 more
    • English
    Immune Biology of Allogeneic Hematopoietic Stem Cell Transplantation provides clinical and scientific researchers with a deep understanding of the current research in this field and the implications for translational practice. By providing an overview of the immune biology of HSCT, an explanation of immune rejection, and detail on antigens and their role in HSCT success, this book embraces biologists and clinicians who need a broad view of the deeply complex processes involved. It then moves on to discuss the immunobiology mechanisms that influence graft-versus-host disease (GVHD), graft-versus-leukemi... (GVL) effect, and transplantation success. Using illustrative figures, highlighting key issues, describing recent successes and discussing unanswered questions, this book sums up the current state of HSCT to enhance the prospects for the future. Allogeneic HSCT is a medical procedure in which a patient receives blood-forming stem cells from a genetically similar but not identical donor. This procedure is commonly performed for people with diseases of the blood, bone marrow, or certain cancers, but it remains risky with many possible complications. As such, experimental practice is reserved for preclinical animal models including the mouse and dog. These animal models have been essential in developing transplant protocols, including preclinical testing of conditioning regimens, treatment of GVHD, and understanding the pathology of GVHD as well as the immunological mechanisms of GVHD and GVL effect. However, recent research has revealed significant species differences between humans and animal models that must be considered when relating animal model studies to clinical allogeneic HSCT scenarios.

  • Clinical Pharmacology During Pregnancy

    • 1st Edition
    • English
    Clinical Pharmacology During Pregnancy is written for clinicians, physicians, midwives, nurses, pharmacists and other medical professionals directly involved in the care of women during pregnancy. This book focuses on the impact of pregnancy on drug disposition and also includes coverage of treatments for diseases of specific body systems as well as essential content on dosing and efficacy. The broad range of this book encompasses analgesics, antiasthmatics, antidepressants, heart and circulatory drugs, vitamins and herbal supplements, and more. Topics in chemotherapy and substance abuse are covered, as are research issues, including clinical trial design and ethical considerations.

  • Advances in Carbohydrate Chemistry and Biochemistry

    • 1st Edition
    • Volume 68
    • English
    Since its inception in 1945, this serial has provided critical and integrating articles written by research specialists that integrate industrial, analytical, and technological aspects of biochemistry, organic chemistry, and instrumentation methodology in the study of carbohydrates. The articles provide a definitive interpretation of the current status and future trends in carbohydrate chemistry and biochemistry.

  • Neurological Rehabilitation

    • 1st Edition
    • Volume 110
    • Michael P. Barnes + 1 more
    • English
    Neurological Rehabilitation is the latest volume in the definitive Handbook of Clinical Neurology series. It is the first time that this increasing important subject has been included in the series and this reflects the growing interest and quality of scientific data on topics around neural recovery and the practical applications of new research. The volume will appeal to clinicians from both neurological and rehabilitation backgrounds and contains topics of interest to all members of the multidisciplinary clinical team as well as the neuroscience community. The volume is divided into five key sections. The first is a summary of current research on neural repair, recovery and plasticity. The authors have kept the topics readable for a non-scientific audience and focused on the aspects of basic neuroscience that should be most relevant to clinical practice. The next section covers the basic principles of neurorehabilitation, including excellent chapters on learning and skill acquisition, outcome measurement and functional neuroimaging. The key clinical section comes next and includes updates and reviews on the management of the main neurological disabling physical problems, such as spasticity, pain, sexual functioning and dysphagia. Cognitive, emotional and behavioural problems are just as important and are covered in the next section, with excellent chapters, for example, on memory and management of executive dysfunction. The final part draws the sections on symptom management together by discussing the individual diseases that are most commonly seen in neurorehabilitation and providing an overview of the management of the disability associated with those disorders. The volume is a definitive review of current neurorehabilitation practice and will be valuable to a wide range of clinicians and scientists working in this rapidly developing field.

  • Bioinformatics of Behavior: Part 2

    • 1st Edition
    • Volume 104
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Bioinformatics of Behavior: Part 1

    • 1st Edition
    • Volume 103
    • English
    This issue of International Review of Neurobiology is split over 2 volumes, bringing together cutting-edge research on Bioinformatics of Behavior. The 2 volumes review current knowledge and understanding, provide a starting point for researchers and practitioners entering the field, and build a platform for further research and discovery.

  • Robotics and Automation in the Food Industry

    Current and Future Technologies
    • 1st Edition
    • Darwin G Caldwell
    • English
    The implementation of robotics and automation in the food sector offers great potential for improved safety, quality and profitability by optimising process monitoring and control. Robotics and automation in the food industry provides a comprehensive overview of current and emerging technologies and their applications in different industry sectors.Part one introduces key technologies and significant areas of development, including automatic process control and robotics in the food industry, sensors for automated quality and safety control, and the development of machine vision systems. Optical sensors and online spectroscopy, gripper technologies, wireless sensor networks (WSN) and supervisory control and data acquisition (SCADA) systems are discussed, with consideration of intelligent quality control systems based on fuzzy logic. Part two goes on to investigate robotics and automation in particular unit operations and industry sectors. The automation of bulk sorting and control of food chilling and freezing is considered, followed by chapters on the use of robotics and automation in the processing and packaging of meat, seafood, fresh produce and confectionery. Automatic control of batch thermal processing of canned foods is explored, before a final discussion on automation for a sustainable food industry.With its distinguished editor and international team of expert contributors, Robotics and automation in the food industry is an indispensable guide for engineering professionals in the food industry, and a key introduction for professionals and academics interested in food production, robotics and automation.

  • Nonisotopic DNA Probe Techniques

    • 1st Edition
    • Larry J. Kricka
    • English
    Recently many nonisotopic methods of probing specific DNA sequences have been developed as replacements for radioactive labels, such as 32phosphorous and 125iodine. This book brings all of these new methods together in one convenient, easily accessible source. It enables researchers to select the nonisotopic method best suited to their application and to use it to maximum advantage by following the straightforward instructions provided.This book contains chapters on colorimetric, bioluminescent, chemiluminescent, fluorescent, and time-resolved fluorescent detection methods. Each chapter has been written by the inventor or developer of a particular nonisotopic method and thus provides an expert account of the method. Each chapterpresents useful background information and detailed, step-by-step, easy-to-follow, experimental procedures for labeling and detection.

  • The Bacteria

    Molecular Basis of Bacterial Pathogenesis
    • 1st Edition
    • Bozzano G Luisa
    • English
    The reviews in this volume deal with questions of the mechanisms of pathogenesis and with organisms that have only recently been extensively studied on the molecular level.**The introductory section presents an overview of pathogenesis, emphasizing common elements and genetic mechanisms of regulation and a review on the population genetics of bacterial pathogenesis. The second section deals with the regulation of synthesis of surface components and their role in the colonization of the host and/or of the host immune systems. The third section covers the invasion and intracellular growth of facultative and obligate intracellular parasites. The last section is devoted to studies of the role of bacterial toxic products in pathogenesis.

  • Designing Antibodies

    • 1st Edition
    • Ruth Mayforth
    • English
    Designing Antibodies provides a compilation of research in the design of antibodies. It describes the techniques used in antibody design, the kinds of antibodies generated through modern techniques, and their applications in medicine and science. The book begins with an overview of the humoral immune system and of antibody structure, function, and biosynthesis, which sets the stage for the subsequent discussions of developments in antibody technology. The remaining chapters discuss the making of monoclonal antibodies; the design of antibodies for human therapy; the connection of antibodies (either chemically or genetically) to other potentially therapeutic effector molecules such as toxins, enzymes, or even an antibody of another specificity; idiotypes and anti-idiotypic antibodies; and the ability of antibodies to functionally mimic enzymes and mediate catalysis. It is hoped that, in addition to illustrating the progress of research in antibody design, the various creative and innovative approaches reviewed in this book will be modified or will stimulate new ideas that will spur the research and application of designer antibodies.

  • Keratinization

    A Survey of Vertebrate Epithelia
    • 1st Edition
    • Nancy Alexander
    • English
    Keratinization: A Survey of Vertebrate Epithelia illustrates the salient features of the epithelial portion of the skin and its appendages in each class of vertebrates, with emphasis on the ultrastructural and functional aspects. Divided into six chapters, this book begins with the general process of keratinization. Then, epithelial differentiation and specialization in the various classes of vertebrates are described. Classes of vertebrates considered are fish, amphibian, reptilian, avian, and mammalian. This treatise is designed to provide an introduction to the study of vertebrate skin and to stimulate professional investigators to delve into its mysteries.

  • Planar Lipid Bilayers

    Methods and Applications
    • 1st Edition
    • W. Hanke + 1 more
    • English
    Biological Techniques is a series of volumes aimed at introducing to a wide audience the latest advances in methodology. The pitfalls and problems of new techniques are given due consideration, as are those small but vital details not always explicit in the methods sections of journal papers.In recent years, most biological laboratories have been invaded by computers and a wealth of new DNA technology and this will be reflected in many of the titles appearing in the series.The books will be of value to advanced researchers and graduate students seeking to learn and apply new techniques, and will be useful to teachers of advanced undergraduate courses involving practical or project work.Methods of constructing artificial membranes (planar lipid bilayers) from the main components of cell membranes (lipids) date from the early 1960s.Planar bilayers offer direct, quantitative experimental approaches to the study of membranes of precisely determined composition which can be manipulated by the experimenter. Pore-forming molecules, transporter molecules, ATP-dependent enzymes and other entities can be incorporated into the bilayers to simulate biological functions.Reconstitu... of such functions in this way remains a key final step in attributing a functional role to purified cell membrane proteins.This book aims to demystify these techniques and begins with a broad overview of the development of the subject before dealing with the protocols involved.Key references are provided at the end of the book together with a list of suppliers.

  • Neurotransmitter Release the Neuromuscular Junction

    • 1st Edition
    • Francesco Clementi
    • English
    Neurotransmitter Release: The Neuromuscular Junction is a collection of papers presented at a small meeting organized in the University of Milan to honor Bruno Ceccarelli. Ceccarelli was particularly interested in the structure and functioning of the neuromuscular junction and spent the rest of his career characterizing the process of neurotransmitter release, and eventually providing the strongest available support for the widely accepted ""vesicle hypothesis"" of neurotransmitter release. The meeting was intended to gather as many scientists who had been directly in touch with Bruno as possible and to discuss together problems of Bruno's interest. Organized into 20 chapters, the book first discusses the organelles of distinct secretory pathways involved in distinct types of neuronal signaling, such as synapsins, synaptophysin , and synaptobrevin. It then examines the role of coated vesicles, acetylcholine compartments, and potassium and calcium channels on neurotransmission processes. Other topics considered are the regeneration of nerve-evoked neurotransmission; the single-channel recordings of KNa in avian sensory neurons; the modulation of voltage-dependent calcium currents in identified snail neurons; and the agonistic/antagonist... action of calcium channel in mammalian peripheral neurons. Cross-talks between receptors coupled to calcium currents and between different intracellular signaling are provided in the last chapters of the book. These chapters also look into the relevance of lipoxygenase metabolites of arachidonic acid to cell-to-cell communication in the central nervous system. This book is an invaluable source for scientists, researchers, and students who are interested in basic neurology.

  • Social Insects V1

    • 1st Edition
    • Henry Hermani
    • English
    Social Insects, Volume I is a part of a four-volume discourse and collection of research on insect sociobiology. This volume covers the “modern theory” with certain concepts of insect sociality, particularly through genetic, behavioral, and evolutionary pathways. This book consists of eight chapters, which mostly deal with the sociality of insects and other aspects. The first chapter provides an introduction to the subject of insect sociality. Topics in this chapter include definition of sociality, types of social insects, and insect sociobiology. The next chapter focuses on the origin and evolution of insect sociality and discusses the theories of origin of sociality. The following chapters discuss the aspects of social insects in terms of antiquity and territoriality. Caste differentiation and division of labor is also emphasized, as well as the genetics of sociality. The last two chapters deal with the larvae of the social hymenoptera and the social and evolutionary significance of social insect symbionts. This volume is a good reference for students and teachers in the study of entomology, zoology, and biology.

  • Molecular Biology and Pathology

    A Guidebook for Quality Control
    • 1st Edition
    • Daniel H. Farkas
    • English
    This is the first handbook to provide an all-in-one guide to establishing molecular biology protocols with requisite quality control. Molecular Biology and Pathology will help professionals sift through the incredible wealth of information available on molecular biology, specifically as it relates to the clinical arena of molecular pathology. This handbook provides excellent training information, and the concern of safety is discussed extensively. The handbook can serve as a primer and reference for those interested in the technical topics described, including the brief discussion of DNA banking. Quality Control (QC) suggestions are also presented.

  • Recombinant DNA Methodology II

    • 1st Edition
    • Ray Wu
    • English
    The critically acclaimed laboratory standard for forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerlyawaited, frequently consulted, and praised by researchers and reviewers alike. More than 250 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences.

  • Viral Transformation and Endogenous Viruses

    • 1st Edition
    • Albert Kaplan
    • English
    Viral Transformation and Endogenous Viruses is a collection of papers presented at the symposium on ""Viral Transformation and Endogenous Viruses"" held at Vanderbilt University on April 1-2, 1974. Contributors discuss the viral function(s) responsible for the transformation of the cells that are infected with oncogenic viruses, emphasizing the type of changes that characterize transformed cells and the regulatory mechanisms that are altered after malignant transformations. This volume is organized into 10 chapters and begins with an overview of DNA-containing tumor viruses, particularly Simian Virus 40 (SV40) and its mutants with DNA deletions, insertions, and duplications. The integration and transcription of adenovirus DNA is considered, along with the characteristics of temperature-sensitiv... mutants of these viruses. The reader is then introduced to the chemistry and biology of RNA-containing tumor viruses, which are useful reagents to study neoplastic transformation both in vivo and in vitro. A major aspect of these viruses concerns the analysis of their genome at the chemical and genetic levels. The last part of the book is devoted to biochemical and genetic analyses of endogenous viruses isolated from avian cells. This book is a valuable resource for scientists and investigators in fields such as pathology, molecular virology, molecular biology, microbiology, oncology, and biochemistry.

  • Cellular and Molecular Neurobiology

    • 2nd Edition
    • Constance Hammond
    • English
    This Second Edition, is the new, thoroughly revised edition of the established and well-respected authoritative text in the field. Cellular and Molecular Neurobiology is hypothesis driven and firmly based on numerous experiments performed by experts in the field. Seven new chapters (five new and two totally rewritten) complement and expand on the first edition and are written in a way that encourages students to ask questions. Additionally, new, groundbreaking research data on dendritic processing is presented in a very easy-to-understand format.

  • Molecular Biology

    Elementary Processes of Nerve Conduction and Muscle Contraction
    • 1st Edition
    • David Nachmansohn
    • English
    Molecular Biology: Elementary Processes of Nerve Conduction and Muscle Contraction focuses on the underlying elementary processes of muscular contraction and nerve impulse conduction. This book explores the fundamental concepts and notions in molecular biology. Organized into 11 chapters, this book starts with an overview of the double array model of striated muscle. This text then discusses the structural changes at the molecular level, which occur as a consequence or an accompaniment of the chemical reactions that occur during contraction. Other chapters explain the process by which molecular changes are summated to produce macroscopic shortenings. This book discusses as well the molecular complementarity and chemistry of acetylcholinesterase... which provides significant information for the understanding of nervous activity. The final chapter deals with the structure of guanidinium ion, which consists of three equivalent NH2 groups arranged with a planar trigonal symmetry around the central carbon atom. Physicists, chemists, and biologists will find this book useful.

  • An Introduction to Animal Law

    • 1st Edition
    • Cooper
    • English
    Legislation relating to animals has ancient origins and in many civilizations certain species have held particular significance, be it religious, cultural, nutritional, or sporting. As a general rule, the law was primarily concerned with animals as property, rather than in need of protection, until the 19th century. Since the 1970s animal law has proved to be a growth area in the production and enforcement of both national and international legislation. This has been particularly so in the areas of conservation and welfare and there has been extensive legal and philosophical consideration of the status of animals.This book is not intended to be a standard text, but rather a handbook in the true sense, a guide for the lay person--namely, to help the non-lawyer to understand the basic concepts of animal law and to provide the lawyer (who is the lay person in the world of animal science) with an introduction to relevant concepts and literature which are not normally found in the conventional legal texts.

  • Isoenzymes In Biology and Medicine

    • 1st Edition
    • Albert Latner
    • English
    Isoenzymes in Biology and Medicine attempts to give an account of the study of isoenzymes in relation to humans, animals, insects, higher plants, fungi, protozoa, algae, and bacteria. This book discusses the chemical structure, physiological aspects, metabolic role, and function of isoenzyme observations in genetic, ontogenic, and phylogenic studies. A detailed account of the use of isoenzyme in the diagnosis and pathogenesis of disease and control of therapy is also provided. This text likewise considers the isoenzymes of the oxidoreductases, transferases, and hydrolases, including its relation to clinical medicine. This publication is intended for biochemists, biologists, clinical biochemists and physicians.

  • Transport And Diffusion Across Cell Membranes

    • 1st Edition
    • Wilfred Stein
    • English
    Transport and Diffusion across Cell Membranes is a comprehensive treatment of the transport and diffusion of molecules and ions across cell membranes. This book shows that the same kinetic equations (with appropriate modification) can describe all the specialized membrane transport systems: the pores, the carriers, and the two classes of pumps. The kinetic formalism is developed step by step and the features that make a system effective in carrying out its biological role are highlighted. This book is organized into six chapters and begins with an introduction to the structure and dynamics of cell membranes, followed by a discussion on how the membrane acts as a barrier to the transmembrane diffusion of molecules and ions. The following chapters focus on the role of the membrane's protein components in facilitating transmembrane diffusion of specific molecules and ions, measurements of diffusion through pores and the kinetics of diffusion, and the structure of such pores and their biological regulation. This book methodically introduces the reader to the carriers of cell membranes, the kinetics of facilitated diffusion, and cotransport systems. The primary active transport systems are considered, emphasizing the pumping of an ion (sodium, potassium, calcium, or proton) against its electrochemical gradient during the coupled progress of a chemical reaction while a conformational change of the pump enzyme takes place. This book is of interest to advanced undergraduate students, as well as to graduate students and researchers in biochemistry, physiology, pharmacology, and biophysics.

  • Dimensions In Health Research: Search For The Medicines Of Tomorrow

    • 1st Edition
    • Herbert Weissbach
    • English
    Dimensions in Health Research: Search for the Medicines of Tomorrow is a collection of papers presented at the 1977 Symposium on Dimensions in Health Research: Search for the Medicines of Tomorrow, held in Basel, Switzerland, sponsored by the Roche Research Foundation for Scientific Exchange and Biomedical Collaboration. This symposium is organized in honor to Professor Alfred Pletscher, a known neurobiologist who led the discovery of drugs for the treatment of various central nervous disorders. This book is organized into three section encompassing 28 chapters. The first section covers the molecular biological aspects of gene expression; the biosynthesis of human interferon; the concept of DNA damage and repair; and the link between advances in molecular genetics and medicine. The second section discusses the pertinent advances in understanding the mechanism of immune system and its components. The third section surveys the trends in pharmacotherapy based on monoaminergic, adenosine triphosphate, gamma-amino butyric acid, amino acid, and peptide mechanisms. This book will prove useful to researchers in the fields of molecular biology, immunology, and neurobiology.

  • Development of Perception

    Psychobiological Perspectives
    • 1st Edition
    • Richard Aslin
    • English
    Development of Perception: Psychobiological Perspectives, Volume 2, The Visual System, is the second of two-part series covering vision, audition, olfaction, taste, tactile sensitivity, and sensory-motor activity during ontogenesis. The focus is on approaches to perceptual development that incorporate a psychobiological perspective. The present volume brings together several topics of critical importance to the process of understanding the visual system. The book is organized into three parts. Part A addresses the theoretical and interpretive issues involved in designing and drawing conclusions from research on the development of the visual system. Part B on animal studies of visual development covers the neural and behavioral characteristics of the cat and monkey visual system during the early postnatal period. Part C examines visual development in human infants. Together, these three parts offer a comprehensive coverage of major issues in the structure and function of the developing mammalian visual system. Each chapter emphasizes the behavioral consequences of developing visual functions.

  • Cellular Membranes in Development

    • 1st Edition
    • Michael Locke
    • English
    Cellular Membranes in Development covers the proceedings of the 1963 22nd Symposium on ""The Society for the Study of Development and Growth"" held in Storrs, Connecticut. This book is organized into 10 chapters that discuss the properties, isolation, function, composition, and physiological aspects of membranes. After briefly dealing with the principles of the unit membrane concept, the book describes the properties of lipid membranes of bilayer thickness with biological relevance. The next chapter focuses on hepatic cell and the modifications of the endoplasmic reticulum in cell differentiation in normal and cancerous growth. Another chapter describes the developmental changes in a particular experimental systems and the modification of the membranes by specific treatments using the apical portion of the primary root of Zea mays. The book also discusses the role of the different organelles in development, supporting the idea of topological continuity between the membranes of all the organelles except the mitochondria. Other chapters describe the cytology of oogenesis and fertilization in Pteridium aquilinum; the early events of fertilization in Hydroides and Saccoglossus; and the composition of cell walls of bacteria, yeast, and fungi. Some aspects of the capsules, microcapsules, and sheaths exhibited by some microorganisms are also covered. The last chapters deal with the quantitative aspects of plant cell permeation and permeability function and changes in relation to maturation and growth hormones. The book is an ideal source for cell biologists and researchers, evolutionists, and biochemists.

  • The Transfer of Calcium and Strontium Across Biological Membranes

    • 1st Edition
    • R Wasserman
    • English
    The Transfer of Calcium and Strontium Across Biological Membranes represents the proceedings of a Conference on The Transfer of Calcium and Strontium Across Biological Membranes, held in Cornell University, Ithaca, New York on May 13-16, 1962. This book is organized into seven sections encompassing 22 chapters, and deals first with some of the properties of biological membranes, the general aspects of ion transport, and chelation of divalent cations. These subjects are all important to understand the transfer of calcium and strontium across membranes. The subsequent sections are devoted to the physiological and nutritional aspects of intestinal absorption, with a particular emphasis on the influence of vitamin D and other nutritional factors on the absorption of calcium and strontium. A section describes the biological transfer and movement of calcium and strontium across kidney, mammary gland, nerve, and muscle. The last section examines the behavior of chronically ingested radiostrontium in animals. This section also provides an overview of strontium and calcium metabolism principles.

  • The Macrophage In Neoplasia

    • 1st Edition
    • Mary Fink
    • English
    The Macrophage in Neoplasia is a compilation of papers presented at a workshop held at the Marine Biological Laboratory, Woods Hole, Massachusetts, on October 8-11, 1975. The book presents the many faceted activities of macrophage. This book is divided according to the five sessions of the workshop. First session talks about the role of tumor macrophages in vivo. It then elucidates the macrophage function and indicates how the interaction of macrophages with other cells can alter the host-tumor balance. The remaining sessions, as presented in this book, explore the mechanism of macrophage mediated cytotoxicity, functional expression of macrophages and neoplasia, and the stimulation of macrophage function and applied therapy.

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