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  • Neuropsychiatric Disorders and Epigenetics

    • 2nd Edition
    • Jacob Peedicayil + 1 more
    • English
    Neuropsychiatric Disorders and Epigenetics, Second Edition is a comprehensive reference on the epigenetic basis of common neuropsychiatric disorders. The volume is organized into chapters covering individual neuropsychiatric disorders, from addiction to anxiety and autism spectrum disorders, and is contributed by leading experts in their respective fields. The epigenetic aspects of each disorder are discussed in the context of the full range of associated epigenetic mechanisms, including DNA modification, histone post-translational modification, chromatin organization, and non-coding RNA. A particular emphasis is placed on potential epigenetic interventions when the effects of environmental stimuli on epigenetic states is particularly relevant to disease. This new edition has been fully updated to reflect recent research advances enabled by genomic technologies, as well as therapeutic interventions for previously unmanageable disorders. Several new chapters have been added on disorders or approaches not considered in the earlier edition, including epigenetics and anxiety disorders, epigenetics and neuroimaging in neuropsychiatric disorders, genome-wide approaches to epigenetic research, and the epigenetics of spinal muscular atrophy.

  • Stem Cells and Signaling Pathways

    • 1st Edition
    • Surajit Pathak + 1 more
    • English
    Stem Cells and Signaling Pathways brings together chapters exploring the mechanism of stem cells and the signaling pathways. This book is a very concise and easy-to-use book. It serves as an ideal reference to guide investigators towards further valuable answers on the role of stem cells and will aid basic researchers and scientists in biomedical sciences and tissue engineering and regenerative medicine with a wide variety of interests in stem cell biology linking basic signal transduction for possible future therapies directed to treatments and different diseases.Significant information on signaling has been presented here. Sufficient knowledge has been provided on therapeutic approaches for the treatment of different degenerative disorders.

  • Non-Conventional Starch Sources

    Properties, Functionality, and Applications
    • 1st Edition
    • José Manuel Lorenzo + 1 more
    • English
    Non-Conventional Starch Sources: Properties, Functionality, and Applications presents the use of non-conventional, unutilized, and underutilized sources to isolate, characterize and functionalize starches. Specific attention is paid to the sources’ application in foods as well as their incorporation into packaging through films and coatings. Broken into seven sections, this book addresses sources from fruit seeds, cereals and millets, pseudo-cereals, seeds, roots and tubers, rhizome and legumes. Food scientists, technologists and students and researchers studying related fields will benefit from this important reference.

  • Treatment-Resistant Depression Part B

    • 1st Edition
    • Volume 281
    • English
    Treatment-Resistant Depression, Part B, Volume 281 in the Progress in Brain Research series, highlights new advances in the field, with this new volume presenting interesting chapters on highly relevant topics such as Treatment Resistant Depression in Children and Adolescents, Treatment Resistant Depression in Elderly, Brain Stimulation for Treatment Resistant Depression, Electroconvulsive Therapy for Treatment Resistant Depression, Psychological aspects and Psychotherapy for Treatment Resistant Depression, Psychiatric Rehabilitation and Cognitive Deficit for Treatment-Resistant Depression, Insomnia and Treatment Resistant Depression, and Tinnitus and Treatment Resistant Depression.

  • Pediatric Head and Neck Imaging, An Issue of Neuroimaging Clinics of North America

    • 1st Edition
    • Volume 33-4
    • William T. O'Brien Sr.
    • English
    In this issue of Neuroimaging Clinics, guest editor Dr. William T. O'Brien, Sr., brings his considerable expertise to the topic of Pediatric Head and Neck Imaging. The differential diagnosis of neck masses in pediatric patients differs compared to masses that arise in adults. In this issue, top experts in the field discuss imaging of hearing loss, sinus infections, neck masses, and congenital lesions, and more.

  • Advances in Stem Cells and their Niches

    • 1st Edition
    • Volume 7
    • Susie Nilsson
    • English
    Advances in Stem Cells and their Niches, Volume Seven highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Phage Therapy - Part B

    • 1st Edition
    • Volume 201
    • English
    Phage Therapy - Part B, Volume 201 covers bacteriophage and their isolation, screening, synthetic phage, diagnostics, directed evolution, host interaction, and more. The book's aim is to highlight a number of aspects of phage in a way that can help students, researchers, clinicians, entrepreneurs and stakeholders perform research. Sections cover Phages for the treatment of Pseudomonas aeruginosa infection, Phage for the treatment of Vibrio cholerae infection, Phages for the treatment of Mycobacterium species, Phage therapy for gut microbiome, Phages as delivery vehicles, Phage display, Unlocking the potential of Phages: Innovative Approaches to harnessing Bacteriophages as Diagnostic Tools for Human Diseases, and more. Other sections explore Phage display and human disease detection, Bacteriophage as Cargo and its application in nanomedicine, Phage for drug delivery vehicles, Genome editing for phage design and uses for therapeutic applications, Phage for cancer therapy, and Phage for regenerative medicine and cosmetics.

  • Chromatin Readers in Health and Disease

    • 1st Edition
    • Volume 35
    • Olivier Binda
    • English
    Chromatin Readers in Health and Disease, Volume 35, a new release in the Translational Epigenetics series, gathers and makes actionable our current understanding of how chromatin readers regulate access to genetic information, and how their aberrant regulation can contribute to human pathologies. Chromatin readers discussed include 14-3-3 Dinshaw, ADD, Ankyrin, BAH, BET, BIR, BRCT, bromodomains and Kac readers, chromodomains and chromobarrel readers, citrullination readers, macrodomains and poly-ADP-ribose readers, MBT, PHD and double PHD, PWWP, SUMO (H4K12) readers, Tudor and TTD, UDR and ubiquitin, WD40, YEATS (crotonyl reader), MBD, SRA, and Methyl-RNA readers.In the book, more than a dozen leaders in the field examine a range of protein readers, their relationship to human disease, and the early therapeutics that act as chromatin signaling factors to treat cancers and Huntington's disease, among other disorders.

  • Chromatin Remodeling Complexes and Transcriptional Coregulators

    • 1st Edition
    • Volume 53
    • English
    Chromatin Remodeling Complexes and Transcriptional Coregulators, Volume 53, the latest release in The Enzymes series highlights new advances in the field, with interesting new chapters that cover Perspectives on Chromatin Remodeling, The functions of ISWI-type remodelers in yeast, Conserved mechanisms of NuRD function in hematopoietic gene expression, The SIN3 complex as a metabolic epigenetic regulator, Soft repression and chromatin modification by conserved transcriptional corepressors, The NPAC-LSD2 complex in nucleosome demethylation, Role of intrinsically disordered domains in transcriptional regulation, and Regulation of the Recovery of Cancer from Therapy Exposure by Noncoding RNAs.

  • Medical Image Analysis

    • 1st Edition
    • Alejandro Frangi + 2 more
    • English
    Medical imaging is increasingly at the base of many breakthroughs in biomedical sciences, becoming a fundamental enabling technology of biomedical scientific progress. Medical Image Analysis presents practical knowledge on medical image computing and analysis and is written by top educators and experts in the field. This text is a modern, practical, broad, and self-contained reference that conveys a mix of essential methodological concepts within different medical domains, reflecting the nature of the discipline today, making it suitable as a course text and a self-learning resource.

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