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Elsevier

Books in Life sciences

  • A Synopsis of Rheumatic Diseases

    • 5th Edition
    • Douglas N. Golding
    • English
    A Synopsis of Rheumatic Diseases presents the study and practice of rheumatology. It discusses the aetiology, diagnosis, and management of the rheumatic disorders. It addresses the scientific work on antinuclear antibodies and extractable nuclear antigens. Some of the topics covered in the book are the biology of synovial joints and connective tissue; immunological principles of rheumatic disorders; pathology of the inflammatory reaction; examination of the locomotor system; classification of rheumatic disorders; rehabilitation in chronic arthritis; and the major rheumatic diseases. The rheumatism due to extra-articular causes is covered. The arthritis associated with skin disorders is discussed. The text describes the neoplasms of synovial membrane and tendon sheaths. A study of the hereditary connective-tissue disorders and psychogenic rheumatism is presented. A chapter is devoted to the limb pain syndromes. Another section focuses on the cervical pain and brachial neuralgia. The book can provide useful information to radiologists, doctors, physical therapists, students, and researchers.

  • Planarian Regeneration

    International Series of Monographs in Pure and Applied Biology: Zoology
    • 1st Edition
    • H. V. Brøndsted
    • G. A. Kerkut
    • English
    Planarian Regeneration deals with regeneration problems including embryogenesis and morphogenesis. The book compares the principles involved in the regeneration processes with those in ontogenesis from the egg. The author also reviews the works of Thomas H. Morgan and Charles M. Child which became the basis for systematic scientific investigation of regeneration. The head regenerates vigorously, with a faster rate behind the eyes, then at various levels along the longitudinal axis of the planarian body. A time-graded regeneration includes inhibitory forces and some genetic codes that determine such rate. The time-graded field has been proven by transplantation experiments; the author addresses the morphological structure to which biochemical factors or processes determine the different rate of regeneration. He notes that the nervous system conforms to these processes as shown by studies of Lender and Klein (1961). The author suggests that the study of regeneration in planarians should involve time considerations quantitatively to explain some substance, if any, from the nervous system that activates the cytoplasm of neoblasts, and then the genome. This book will prove valuable for zoologists and researchers in genetics, biochemistry or molecular biology.

  • Extracellular Matrix Assembly and Structure

    • 1st Edition
    • Peter D. Yurchenco
    • English
    The complex and critical process of extracellular matrix (ECM) assembly is described in this book. Assembly may involve molecules interacting with molecules of the same matrix class, such as in collagen, or interactions between different ECM molecules, such as in basement membranes. The text shows how this is driven by structural information within the matrix monomer. This information will be of interest to cell, developmental, and molecular biologists, biochemists, biophysicists, and biomedical researchers involved in macromolecular assembly, biological macromolecules, and extracellular matrix.

  • Plant Tissue Culture and Its Agricultural Applications

    Proceedings of Previous Easter Schools in Agricultural Science, Published by Butterworths, London
    • 1st Edition
    • Lyndsey A. Withers + 1 more
    • English
    Plant Tissue Culture and Its Agricultural Applications presents the proceedings of the 41st University of Nottingham Easter School in Agricultural Science held in England. The sessions covered in this volume reflect the revolution of tissue culture and its role in the propagation of elite plant material and the development of improved genotypes. This book is organized into four main sections. The first section chronicles the revolution of the plant tissue culture. This includes papers on clonal propagation, morphogenesis, germplasm storage, plant health, and genetic improvement. The core of this volume is covered by the introductory and the final chapters which interrelate the different subjects areas covered by the proceedings and provide a realistic assessment of future research required for the plant tissue culture revolution to come to fruition. This book will be useful to readers interested in understanding the history, evolution, and future of plant tissue culture and its applications in the agricultural sector.

  • Physiology of Echinoderms

    International Series of Monographs in Pure and Applied Biology Zoology
    • 1st Edition
    • John Binyon
    • G. A. Kerkut
    • English
    Physiology of Echinoderms is an 11-chapter book that begins by elucidating the feeding, digestion, and excretion of specific echinoderms. The critical role of amoebocytes in the excretion process involved in these organisms is also explained. This book also describes several aspects of importance to these organisms, including salinity tolerance, osmoregulation, ionic regulation, chemical composition, neural control of locomotion, biochemical affinities, toxins, and immunology. The organisms' physiology in sensory, water vascular system, respiratory system, spawning, neurosecretion, nerves, and muscles are also explained.

  • Cyclic Phenomena in Marine Plants and Animals

    Proceedings of the 13th European Marine Biology Symposium, Isle of Man, 27 September - 4 October 1978
    • 1st Edition
    • E. Naylor + 1 more
    • English
    Cyclic Phenomena in Marine Plants and Animals covers the proceedings of the 13th European Marine Biology Symposium. The title presents papers that tackle the cyclical biological processes in population ecology, developmental biology, metabolism, and the behavior of marine organisms. The text first covers topics about the population cycles of flora and fauna. Next, the selection details the rhythmic aspects of reproduction and growth, and then proceeds to discussing the cyclical aspects of production and metabolism. The text also deals with the rhythmic behavior and its control by environmental and physiological factors. The book will be of great use to students, researchers, and practitioners of marine biology and ecology.

  • Clinical Ocular Pharmacology

    • 2nd Edition
    • Jimmy D. Bartlett
    • English
    Clinical Ocular Pharmacology, Second Edition covers the diagnostic and therapeutic clinical procedures in the administration of drugs to the eye. This book is organized into five parts encompassing 35 chapters that evaluate the basic pharmacologic principles that govern the different types of ophthalmic drugs. It addresses the pharmacologic agents useful in the diagnosis and treatment of ocular diseases. Some of the topics covered in the book are the basic science of ocular pharmacology; clinical administration of ocular drugs; drugs affecting the autonomic nervous system; types of local anesthetics; review of anti-inflammatory drugs; and examination of inhibitors of aqueous formation. Other parts deal with the development of contact lens solution in clinical practice and the pharmacologic management of strabismus. These topics are followed by discussions of the legal basis of using drugs in optometry and the systemic effects of ocular drugs. The concluding part is devoted to the diseases of the optic nerve. The book can provide useful information to doctors, optometrists, pediatricians, students, and researchers.

  • Malnutrition in Chronic Diet-Associated Infantile Diarrhea

    Diagnosis and Management
    • 1st Edition
    • Carlos H. Lifschitz + 1 more
    • English
    Malnutrition in Chronic Diet-Associated Infantile Diarrhea: Diagnosis and Management documents the proceedings of eighth annual symposium on nutrition research. The symposium addressed the complex problem of ""Enteropathy of Infantile Malnutrition"" by assembling a distinguished group of international scientists at the Children's Nutrition Research Center, Baylor College of Medicine in Houston, Texas. Leading experts in the fields of pathology, immunology, gastroenterology, and nutrition reviewed the state of knowledge on the topic; researchers from countries including Sweden, the People's Republic of China, Brazil, India, Australia, and the United States presented the latest findings from field studies. The volume contains 52 chapters organized into seven parts. Part I contains papers on intestinal mucosal histology in infantile malnutrition and chronic diarrhea. Part II presents studies on Intestinal mucosal immunology. Part III examines the epidemiological relationship between malnutrition and chronic diarrhea in infants and children. Part IV focuses on the diagnosis and dietary and pharmacological management of chronic diarrhea. Part V deals with clinical disorders of transient carbohydrate malabsorption. Part VI reports on the terminology and classification of patients with malnutrition in chronic diet-associated infantile diarrhea while Part VII discusses future research priorities.

  • International Review of Connective Tissue Research

    Volume 9
    • 1st Edition
    • David A. Hall + 1 more
    • English
    International Review of Connective Tissue Research, Volume 9 provides information pertinent to the fundamental aspects of connective tissue research. This book reviews the methods involved in chromosome mapping of genes and their application to genes. Organized into six chapters, this volume begins with an overview of basement membranes updates. This text then examines the widespread use of the methods of immunofluorescence and immune electron microscopy. Other chapters consider the degradation of collagen in vivo that is of necessity under close biological control. This book discusses as well the nature and role of inhibitors of the collagenolytic enzymes in normal and pathological conditions. The final chapter emphasizes that in addition to the multiplicity of functions of connective tissue in various organs, the formation of this tissue is the major mechanism of the repair of damaged tissues in species that have lost the power of regeneration. This book is a valuable resource for biochemists.

  • Drug Design

    Medicinal Chemistry: A Series of Monographs, Vol. 5
    • 1st Edition
    • E. J. Ariëns
    • English
    Drug Design, Volume V covers the fundamental approaches to the development of bioactive compounds. The book discusses the utilization of operational schemes for analog synthesis in drug design; the design of enzyme inhibitors (transition state analogs); and the significance of structure-absorption... relationships for drug design. The text describes the role of charge-transfer processes in the action of bioactive materials, as well as the approaches to the rational combination of antimetabolites for cancer chemotherapy. The physicochemical, quantum chemical, and other theoretical techniques for the understanding of the mechanism of action of central nervous system (CNS) agents, such as psychoactive drugs, narcotics, and narcotic antagonists and anesthetics, are also encompassed. Chemists, biochemists, pharmacologists, and people involved in drug design will find the book invaluable.

  • Genetic Interactions Among Microorganisms in the Natural Environment

    • 1st Edition
    • E.M.H. Wellington + 1 more
    • English
    This book gives an overview of gene transfer and stability in those aquatic and terrestrial environments where bacteria and fungi can survive and interact genetically. It examines the role played by sex between microbes in the evolution of populations and their survival. Special emphasis is placed on methodology, including the analysis by novel techniques of genetic material extracted directly from soils, rivers and lakes. The natural spread of antibiotic resistance and the safe use of genetically manipulated microbes are matters of considerable scientific, medical and public concern upon which the investigations presented here have direct bearing. This unique collection will be of value to specialist researchers in applied microbiology, ecology and biotechnology as well as biomedical scientists interested in the environmental risks of genetic engineering.

  • Spinal Degenerative Disease

    • 1st Edition
    • R. S. Maurice-Williams
    • English
    Spinal Degenerative Disease aims to provide a guide to the subject of spinal degenerative disease in all its aspects and to provide a balanced account of the more controversial parts of this field. It was written to fill the lack of books that deal with the degenerative disease of the vertebral column. This book is organized into 14 chapters that attempt to cover not only the pathology, clinical features, and treatment of spinal degenerative disease but also some relevant topics such as radiological techniques used in spinal investigation and the relationship between spinal arachnoiditis and degenerative disease. The book also discusses the relevant aspects of normal spinal physiology and anatomy and the differential diagnosis of spinal pain and sciatica. It also provides case histories to illustrate various points. This book will be of interest to students, medical professionals, and others interested in understanding the pathology and treatment of spinal degenerative disease.

  • Muscle Function Testing

    • 1st Edition
    • Vladimír Janda
    • English
    Muscle Function Testing provides information pertinent to the muscle functions. This book evaluates the method of examination that provides information about the strength of individual muscles or muscle groups that form a functional unit. Organized into three sections encompassing four parts, this book begins with an overview of the size, extent, and progress of peripheral nerve lesions. This text then discusses the nature of the simple movement pattern seen in muscle function testing. Other chapters consider the conditions for analytical physiotherapy and determination of the work capacity of the part of the body being tested. This book discusses as well the possible errors and mistakes that might occur during testing and might decrease the validity of the assessment. The final chapter deals with the demand for a better and a more rational method to therapeutic exercise. This book is a valuable resource for physiotherapists, orthopedic surgeons, physiologists, neurologists, and rheumatologists.

  • The Biology of the Mollusca

    • 2nd Edition
    • R. D. Purchon
    • G. A. Kerkut
    • English
    Reviews the most important literature on the functional morphology and natural history of molluscs over a period of half a century, from 1925 to the present day, and draws extensively upon authoritative papers published mostly in the English language in a large number of international journals during this period. By these means it is hoped to provide an anthology of what is most interesting in the literature in a number of selected topics. Appendices give some practical assistance for the dissection of selected examples

  • Cooperative Phenomena in Biology

    • 1st Edition
    • George Karreman
    • English
    Cooperative Phenomena in Biology deals with cooperation in biology and covers topics such as cooperative specific adsorption; the kinetics of oxygen binding to hemoglobin; allosteric control of cooperative adsorption and conformation changes; and cooperativity in biological surfaces responding to topical treatment. The use of Monte Carlo methods to investigate the behavior of cooperative Ising models is also described. This book is comprised of five chapters and opens with a discussion on the phenomenon of cooperative specific adsorption and its importance for the understanding of fundamental biological phenomena. The derivation of the cooperative specific adsorption isotherm both stochastically and on the basis of statistical mechanics is explained. The next chapter reviews the theory of the allosteric control of cooperative adsorption and conformation changes and outlines a molecular model for physiological activities according to the association-inductio... hypothesis. The reader is also introduced to a kinetic equation for hemoglobin oxygenation based on the infinite chain; the use of bioelectrometric methods to study solute interactions with biocolloidal surfaces responding to topical treatment; and the use of Monte Carlo computations to determine the behavior of cooperative Ising models. This monograph is intended for biologists, physicists, chemists, and mathematicians.

  • The Chemistry and Technology of Edible Oils and Fats and Their High Fat Products

    • 1st Edition
    • G. Hoffmann
    • Steve L Taylor
    • English
    The Chemistry and Technology of Edible Oils and Fats and their High Fat Products covers the theoretical and practical aspects associated with the chemistry and technology of oils and fats. The book discusses the chemistry of edible fats; vegetable-oil separation technology; and water- and heat-promoted fat separation from animal and plant "fatty tissues". The text also describes the refining process; the fat-modification processes; and the production of edible-fat products of high fat content. The technologies applied to speciality fats; the storage and transport of oils and fats; and energy demands of the oil-milling and edible-fat processing operations. People involved in the processing of edible oils and fats will find the book useful.

  • Clinical Pharmacology

    Proceedings of the 7th International Congress of Pharmacology, Paris 1978
    • 1st Edition
    • P. Duchêne-Marullaz + 2 more
    • English
    Clinical Pharmacology provides a detailed discussion on toxicology. This discussion includes the chemotherapy of parasitic diseases. Some parts of the book focus on topics on immunopharmacology. Such topic as the genetic and environmental factors that contribute to individual’s varying response to drugs is explained. The book covers such topics as the methods and models for the isoniazid acetylation polymorphism. The issues that arise in the administration of drugs in the neonatal period are assessed. Another topic of interest is the effects of diseases on the absorption of drugs. The pharmacokinetic and pharmacodynamic characteristics of a drug are evaluated. The pharmacogenetic investigation amobarbital disposition is presented completely. The book then presents the use and consumption of drugs in different locations and some clinical considerations. The procedures and methods of analysis for such drug are also reviewed . The book can serve as a valuable tool for pharmacists, medical doctors, pediatricians, students, and researchers in the field of medicine.

  • Woodlice

    • 1st Edition
    • S. Sutton
    • English
    Woodlice are one of the few land-living groups of the class Crustacea. In order to live in such a harsh environment, they have evolved many structural and behavioural mechanisms to conserve water. This book covers not only the morphology and physiology of woodlice but also the behaviour, genetics and population ecology. The parasites and predators, and distribution and range of the British species are described. A checklist of British species of woodlice accompanies an illustrated identification key. Practical ideas of study techniques are supported by many suggestions for further investigation - many of which are accompanied by detailed instructions

  • Selected Topics in Environmental Biology

    Based on the Sessions on Environmental Biology Held at the XXVI International Congress of Physiological Sciences, New Delhi, October 20-26, 1974
    • 1st Edition
    • Balraj Bhatia + 2 more
    • English
    Selected Topics in Environmental Biology covers the proceedings of the 26th International Congress of Physiological Sciences on Environmental Biology, held in New Delhi, India on October 20-26, 1974. The symposium is arranged in the subjects of high altitude and under water physiology and the physiological effects of cold, heat, and accelerations. This book is organized into 13 sections encompassing 74 chapters. The opening part deals with the principles and mechanisms of thermoregulation, with emphasis on the role of neurotransmitters in temperature regulation. The succeeding parts examine metabolic aspects and adaptive mechanisms to cold and heat stress. These parts also survey the thyroid function, resistance, acclimatization, and nerve impulse effects of these conditions. Other parts discuss the hypothalamic control and susceptibility to hypothermia and thermal injury; the capacity of short-term and prolonged exposure to hypoxia; the pathogenesis of pulmonary edema; and the constitution and body functions in different ethnic groups. These topics are followed by reviews on the body adaptive changes under hypogravic state, biochemical changes induced by environmental pollution, and physiological behavior under noise, hyperbaric, and emotional stress. The last part describes the effect of environmental stress on diurnal variations in body functions. This book will prove useful to environmental biologists, physiologists, biochemists, and researchers.

  • Evolution

    Evolution
    • 1st Edition
    • Volume 10
    • E. R. Trueman + 1 more
    • English
    FROM THE GENERAL PREFACE: This multivolume work, The Mollusca, had its origins in the mid 1960s with the publication of two volumes entitled Physiology of Mollusca and edited by Wilbur and Yonge. In those volumes, 27 authors collaborated to summarize the status of the conventional topics of physiology as well as biochemistry, reproduction and development, and ecology. Within the past two decades, there has been a remarkable burgeoning of molluscan research generally and with it the development of new fields of investigation. During the same period, several excellent books on molluscs have appeared. However, they do not provide adequate information on the many recent advances or give the breadth of perspective of current knowledge of the phylum. Clearly, there was need for a larger work with a comprehensive treatment of major areas of molluscan research. The Mollusca, as a series of 12 volumes, attempts to fulfill this objective. Even here, practical considerations have meant that certain aspects of molluscan research have not been included.Each major area is treated by several authors, each reviewing his or her special field. The areas are structure and function, metabolic biochemistry, molecular biomechanics, environmental biochemistry, physiology, ecology, reproduction and development, neurobiology and behavior, and evolution. Throughout, the authors have given emphasis to recent advances and present status of molluscan biology. In so doing, directions of future research have become evident.The Mollusca is intended to serve several disciplines--zoology... biochemistry, physiology, and paleontology. It will prove useful to researchers and to all others with interests in molluscs.FROM THE PREFACE TO VOLUME 10: Recent events that have stimulated a great surge of investigation into the evolution of the Mollusca include the discovery of well-preserved microscopic molluscs at most levels of the Cambrian on five continents, the development of electron microscopy, the need to examine competing models of the early history of the phylum, new interest in interstitial fauna of littoral and near-littoral sands, and significant advances in our knowledge of shell ontogeny, construction, and evolution. It is timely that an up-to-date synthesis involving both paleontologists and zoologists should be published after a decade of such activity and advance when many of the long-held views on molluscan phylogeny have been overturned.This book deals with all molluscan classes except the Cephalopoda, which will be treated in Volume 12. The two books together provide an up-to-date introduction to the evolution of the Mollusca with adequate references to guide further work. They will be invaluable to specialists on molluscs, postgraduate research workers, and undergraduates with particular interests in this phylum. Authorities on the various molluscan groups were asked to express their views and to treat the subject as they wished; the book provides a valuable record of their opinions at this time.While the main groups are broadly and fully treated, focus has been narrowed toward a few selected minor groups of particular interest such as limpets, land snails, and the Anomalodesmata, in which recent work has been particularly significant.Because recent years have seen major revisions in classificatory terms, the editors have provided an outline classification into which the chapter topics fit.

  • Life Sciences and Space Research

    Proceedings of The Open Meetings of The Working Group on Space Biology of The Twentieth Plenary Meeting of COSPAR, Tel Aviv, Israel, 7-18 June 1977
    • 1st Edition
    • R. Holmquist + 1 more
    • English
    Cospar Life Sciences and Space Research, Volume XVI covers the proceedings of the Open Meetings of the Working Group on Space Biology of the 20th Plenary Meeting of COSPAR, held in Tel Aviv, Israel, on June 7-18, 1977. The book focuses on the developments in space explorations; approaches for the creation of extraterrestrial intelligence; and biochemical mechanism of the visual-light-flash phenomena. The selection first discusses the Viking Lander biology experiments on Mars. The experiments returned detailed picture of the Martian soil surface chemistry. The text also takes a look at a preliminary search for narrowband signals at microwave frequencies; observational program options and system requirements for the search of extraterrestrial intelligence; and public health considerations related to a Mars surface sample return mission. The book reviews planetary protection guidelines for outer planet missions, including Viking clean room technology, efficacy of clean room assembly, and Jupiter Orbiter Probe PP appraisal. The text also focuses on the effects of temperature, salinity, and other factors on the growth and formation of UV-absorbing substances by the fungus aspergillus; effects of gravitational and magnetic fields on transplanted neuroblastoma vascularity; and the roles of body mass and gravity in identifying the energy requirements of homoiotherms. The selection is a dependable reference for readers interested in space research.

  • Biochemical and Molecular Aspects of Selected Cancers

    Volume 2
    • 2nd Edition
    • Thomas G. Pretlow II
    • English
    This two-volume work not only includes much of the newer molecular biology research but also important earlier research in this area essential for the comprehensive understanding of the biochemistry of neoplastic diseases. As such it will provide an invaluable source of information for the young investigator. Human cancers, not experimental models of cancer, are emphasized.

  • Metabolic Diseases in Farm Animals

    • 1st Edition
    • Jack M. Payne
    • English
    Metabolic Diseases in Farm Animals discusses metabolic diseases in farm livestock, focusing on four clinical syndromes—parturient hypocalcaemia, hypomagnesaemia, ketosis, and bloat. This book discusses metabolic disorders associated with water, calcium, magnesium, sodium, potassium, nitrogen, and phosphorus. The parturient paresis, which causes considerable metabolic stress and disrupts the daily pattern of feeding and digestion of dairy cows is also elaborated. This text covers the changes in mineral metabolism at parturition; factors predisposing dairy cows to parturient paresis; cause of paresis in milk fever; and downer syndrome in dairy cows. The complexity of energy metabolism and its associated disorders are likewise described. This publication is a good source for veterinarians and livestock farmers concerned with metabolic diseases in farm animals.

  • Comprehensive Insect Physiology, Volume 4

    Regulation: Digestion, Nutrition, Excretion
    • 1st Edition
    • G. A. Kerkut
    • English
    In this volume, seven of the chapters deal with feeding and diet, which is reasonable since insects consume an estimated l5-20% of all the world's planted crops. Many insects even have a specialized larval feeding stage that usually occupies a different ecological niche to the adult and so does not compete for the adult's food stock. Other chapters describe the means by which insects maintain their water balance, nitrogen balance and temperature balance under a range of conditions. These involve regulation by hormonal and behavioural systems that are also described here. The l4 chapters are all extensively illustrated and referenced and therefore provide excellent summaries of current knowledge. They will be of great value to entomologists, zoologists and biologists in general.

  • Biochemistry of Brain

    • 1st Edition
    • Sudhir Kumar
    • English
    Biochemistry of Brain is a collection of articles dealing with the developments in the biochemistry of the brain. This book gives a comprehensive and critical discussion of important developments in studies concerning the above subject. This text discusses the structure, function, and metabolism of glycosphingolipids, which are related to the study of sphingolipid storage diseases. Inborn defects of metabolism are found in Gaucher's and Fabry's disease, which are characterized by lipid accumulation in the brain. Another paper reviews the chemical and genetics of critically lysosomal hydrolase deficiencies that can cause the storage of sphingolipids. This book then explains the role of myelin basic protein in lipids in vivo that the weak bonding of the protein is not a major component of myelin stability. Another paper discusses the procedures for isolating subfractions of myelin and myelin-related membranes, with some attention given on the alterations in the subfractionation of myelin in pathological hypomyelinating and demyelinating conditions. Another article discusses the biochemical and enzymatic composition of lysosomes and the biosynthesis, intracellular transport, storage, and the degradation of lysosomal constituents. This collection of papers will benefit scientists doing research in microbiology, microchemistry, molecular genetics, and neurochemistry.

  • Discovery of Novel Natural Products with Therapeutic Potential

    • 1st Edition
    • Vincent P. Gullo
    • English
    Although science has discovered effective drugs for many of the diseases that afflict mankind, many human health problems remain untreatable. The search for novel therapeutic agents is always ongoing. This book will describe some of the diverse sourcesof natural products, such as terrestrial and marine environments; and will review how research has increased knowledge of biological systems and human disease, leading to the design of targeted asssays, amenable to high volume screening.

  • Biological Cycles

    Current Topics in Cellular Regulation, Vol. 18
    • 1st Edition
    • Ronald W. Estabrook + 1 more
    • English
    Current Topics in Cellular Regulation, Volume 18: Biological Cycles covers topics on the events of molecular biology, cellular communication, and the merging of cell structure to biochemical function. The book discusses the ornithin-urea cycle; the cycles of glutathione metabolism and transport; and the role of multienzymatic proteins in mammalian pyrimidine biosynthesis. The text also describes the significance of interconvertible enzyme cycles in cellular regulation; regulation of mammalian pyruvate dehydrogenase complex by a phosphorylation-deph... cycle; replenishment of citric acid cycle intermediates by the purine nucleotide cycle in rat skeletal muscle. The control of a secondary pathway of ethanol metabolism by differences in redox state; the role of aldolase and fructose bisphosphatase in the control of gluconeogenesis and glycolysis; and the fructose 6-phosphate/fructose 1,6-bisphosphate cycle are also considered. The book further tackles the cycles in polysaccharide biosynthesis and other important biological cycles. Biologists, microbiologists, cellular biologists, and biochemists will find the book invaluable.

  • New and Updated Methods

    Analytical Methods for Pesticides and Plant Growth Regulators, Vol. 10
    • 1st Edition
    • Gunter Zweig + 1 more
    • English
    Analytical Methods for Pesticides and Plant Growth Regulators, Volume X: New and Updated Methods covers the specific methods (i.e. gas chromatography, thin-layer chromatography, spectroscopy, high-performance liquid chromatography, and thin-layer densitometry) of analysis for formulations and residues of pesticides (i.e. insecticides, fungicides, herbicides, plant growth regulators, nematicides, and soil fumigants) of international importance. Toxicologists and people involved in the research of analytical methods for the formulations of pesticides will find the book invaluable.

  • A Guide to Alcohol and Drug Dependence

    • 2nd Edition
    • J. S. Madden
    • English
    A Guide to Alcohol and Drug Dependence, Second Edition provides information on the recognition of alcohol misuse, on alcohol dependence among the elderly, and on outpatient withdrawal from opioids. This book emphasizes the detection and early treatment of alcohol misuse, the detoxification of drug users followed by drug-free counseling, and preventive measures. Organized into nine chapters, this edition begins with an overview of the various types of dependence-producing drugs, including morphine, cocaine, cannabis, alcohol-barbiturate, amphetamine, hallucinogen, and inhalants and volatile solvents. This text then explains the depressant actions of alcohol on the central nervous system that affects first the higher cerebral functions responsible for concern about personal behavior and for self-restraint. Other chapters consider the physical disabilities that heavy drinkers are prone to develop. The final chapter deals with the preventive measures directed against the problems presented by drugs and alcohol. This book is a valuable resource for social workers, nurses, occupational therapists, and clinical psychologists.

  • Coastal Environments

    An Introduction to the Physical, Ecological, and Cultural Systems of Coastlines
    • 1st Edition
    • R. W.G. Carter
    • English
    This original volume draws on the author's own research experiences in Ireland, Britain, France, Canada, and the United States to present a guide of coastal environments for applications of shoreline and environmental management. Topics include: long-term development of coasts, water supply and waste disposal, energy resources and coastal water management, coastal water management for recreation, coastal management of storm hazards, and managing world sea-level rise.

  • Foundations of Mathematical Biology

    Subcellular Systems
    • 1st Edition
    • Robert J. Rosen
    • English
    Foundations of Mathematical Biology, Volume 1, Subcellular Systems, provides an introduction the place of mathematical biology in relation to the other biological, physical, and organizational sciences. It discusses the use of mathematical tools and techniques to solve biological problems. The book contains four chapters and begins with a discussion of the nature of hierarchical control in living matter. This is followed by a chapter on chemical kinetics and enzyme kinetics, covering the physicomathematical principles, models, and approximations underlying transition-state theory and the unimolecular reaction. Subsequent chapters deal with quantum genetics and membrane excitability.

  • Membrane Fluidity in Biology

    Cellular Aspects
    • 1st Edition
    • Roland C. Aloia + 1 more
    • English
    Membrane Fluidity in Biology, Volume 4: Cellular Aspects provides a unique interpretation of membrane and cellular activity, as well as cellular aspects of membrane fluidity. This book discusses the influence of membrane fluidity on enzyme activity, function of the sarcoplasmic reticulum in skeletal muscle, role of cholesterol in membrane function, phospholipid methylation, glycosyltransferases... and membrane fusion. The realm of normal cellular function and mechanisms involved in the modulation of cellular function by membrane lipids are also elaborated in this publication. This volume is intended for cell and molecular biologists and clinical-medical scientists, but is also beneficial to individuals researching on the effects of membrane lipids and fluidity in cellular function.

  • Advances in Drug Research

    • 1st Edition
    • Volume 22
    • Bernard Testa
    • English
    Advances in Drug Research, Volume 22 focuses on the concepts and facts of drug research. This book is divided into four chapters. Chapter 1 discusses the use of atomic properties and atom-centered indices in QSAR models, while Chapter 2 describes the pharmacokinetics of peptides and proteins. The nuclear receptors, emphasizing the aspects of molecular and genomic pharmacology are elaborated in Chapter 3. The last chapter covers the medicinal chemistry of a vast group of agents acting on nuclear receptors. This publication is valuable to drug researchers and students interested in advances in drugs.

  • The Catecholamines in Psychiatric and Neurologic Disorders

    • 1st Edition
    • C. Raymond Lake + 1 more
    • English
    The Catecholamines in Psychiatric and Neurologic Disorders focuses on the contributions of catecholamines (CA) in the modulation of blood pressure, stress and exercise, body movements, memory, learning, emotions, thought processing, appetite, and mediation of psychotropic drug action. The selection first elaborates on the techniques for the assessment and interpretation of catecholamine measurements in neuropsychiatric patients and catecholaminergic response to stress and exercise. Discussions focus on noradrenergic response to isometric exercise, isotonic exercise, effect of acceleration on sympathetic activity, techniques for sympathetic nervous system evaluation, and measurements of CA and their metabolites in cerebrospinal fluid. The text then takes a look at urinary CA in behavioral research on stress; CA in anxiety disorders and mitral valve prolapse; and interaction with neurotransmitters in normal subjects and in patients with selected neurologic diseases. The selection examines noradrenergic responses in postural hypotension, norepinephrine, alcohol, and alcoholism, and catecholamine metabolism in anorexia nervosa. Topics include cerebral catecholamine metabolism in anorexia nervosa; central nervous system norepinephrine and voluntary alcohol drinking; and overview of norepinephrine in selected pediatric disorders. The book is a dependable reference for neuropsychiatrists and readers interested in the contributions of catecholamines on psychiatric disorders.

  • Enzymes in Blood Plasma

    • 1st Edition
    • Benno Hess
    • English
    Enzymes in Blood Plasma gives a comprehensive account of the current state of research and practical application of biochemistry and biology, as well as the pathology and clinical aspects of plasma enzymes. Enzymes in blood plasma, for reasons of principle and methods, are not limited to plasma-specific enzymes, which are only briefly mentioned. Emphasis will rather be placed on plasma-nonspecific enzymes, i.e., enzymes of identical properties in plasma and serum. Their action is, for technical reasons, generally determined in serum. The enzymes in plasma will be stressed in this presentation, but the situation in other extracellular spaces and even extracorporeal areas such as urine, excreta, and feces will be included. There exists no basic difference of enzyme function in these biological areas. Many of the findings reported in this volume were obtained with the old units and methods, rather than the International Unit. For this reason, the section dealing with methods includes a table for conversion, which can be used for comparison of data, insofar as these data were obtained under optimalconditions of measurement.

  • New Protein Foods

    Technology
    • 1st Edition
    • Aaron M. Altschul
    • English
    New Protein Foods, Volume 2: Technology, Part B covers examples of mixtures of pure amino acids used in medicine, as well as of the vast social possibilities inherent in exploiting pure synthetic nutrients. The book discusses new approaches to marketing fish; new approaches to marketing milk products; and extrusion cooking. The text also describes the development of the particular knowledge in nutrition and food science and technology that allowed the first chemically defined, almost complete, synthetic foods to be produced. The role of flavor in new protein technologies; mass and institutional feeding of protein foods; and the use of nutrient intervention to improve nutritional status are also considered. The book further tackles the AID program for the introduction of new protein technologies; the notable happenings occurring in the technology and marketing of meat analogs; and the limits of technology.

  • Biological Oxidants: Generation and Injurious Consequences

    Volume 4
    • 1st Edition
    • Charles G. Cochrane + 1 more
    • English
    Biological Oxidants: Generation and Injurious Consequences is a collection of papers that describes research work done concerning molecules of the intracellular and plasma membrane generating system in leukocytes; the intracellular interactions in oxidant-induced cellular injury; malignant transformation; and intracellular mechanism of oxidant formation. One paper reviews biological oxidants and the molecular basis of chronic granulomatous disease, particularly on compositions found within the plasma membrane. One such composition concerns the discovery of a flavocytochrome b as the central electron-transportin... molecule in this system. Another paper examines the early injury of cells caused by external oxidants and the consequences of DNA damage. Other papers review the metabolism of vascular endothelial-derived reactive species, the calcium-modulated cellular effects of oxidants, as well as, the mechanism of inflammatory oxidant damage in tissues. This book is suitable for biochemists, microbiologists, and academicians whose works involve research of cell membranes.

  • Lipid Metabolism in Signaling Systems

    • 1st Edition
    • Volume 18
    • P. Michael Conn + 1 more
    • English
    Many of the phospholipases and even the receptor for inositol 1,4,5-trisphosphate have recently been cloned and sequenced and play an important role in neurotransmission. Methods developed in recent years for the study of the enzymes and intermediates involved in the regulation of neuronal signal transduction involving phospholipid turnover are presented in this volume.

  • Advances in Pharmacological Research and Practice

    Proceedings of the 4th Congress of the Hungarian Pharmacological Society, Budapest, 1985
    • 1st Edition
    • J. Knoll + 1 more
    • English
    Advances in Pharmacological Research and Practice, Volume 1: Pharmacological Protection of the Myocardium presents the proceedings of the 4th Congress of the Hungarian Pharmacological Society, held in Budapest, Hungary in 1985. This book presents a comprehensive view of the development in the fields of pharmacological protection of the myocardium and the pharmacology of the vascular system. Organized into two sections encompassing 70 chapters, this volume begins with an overview of the ischemic biochemical changes with emphasis on the role of cAMP and the protein kinase system. This text then explores the cellular electrophysiological disorders seen in acute myocardial ischemia as well as their pharmacological modification. Other chapters consider the prevention of primary ventricular fibrillation that includes measures aimed at maintaining electrical stability. The final chapter deals with drugs affecting beneficially the pathological lipoprotein levels. This book is a valuable resource for cardiologists and pharmacologists.

  • Fetal Endocrinology

    • 1st Edition
    • Miles J. Novy + 1 more
    • English
    Fetal Endocrinology covers many facets of primate reproductive biology. The book discusses some thoughts on the fetoplacental unit and parturition in primates; the development and function of the human fetal adrenal cortex; and postnatum evolution of the adrenal glands of rhesus macaques. The text also describes the regulation of fetoplacental steroidogenesis in rhesus macaque; the comparative biological, immunologic, and chemical properties of the primate chorionic gonadotropins; and urinary estrogens during pregnancy in diverse species. The secretion and physiology of chorionic somatomammotropin in primates; the placental thyroid stimulators and thyroid function in pregnancy; and growth factors in fetal growth and development are also considered. The book further tackles the production and activity of placental releasing hormone; the endocrinology of parturition; and sex-determining genes and gene regulation. The text also looks into the testicular hormone production in fetal rhesus macaque; the control of pituitary gonadotropin secretion in fetal rhesus macaque; and the development of the regulatory mechanisms of the hypothalamic-pituita... system in the human fetus. The development of the fetal adrenals in nonhuman primates and perspectives in fetal endocrinology are also encompassed. Reproductive physiologists, pediatricians, gynecologists, and endocrinologists will find the book invaluable.

  • Agricultural Insurance

    Theory and Practice and Application to Developing Countries
    • 2nd Edition
    • P. K. Ray
    • English
    This book, which deals comprehensively with agricultural insurance, is the second edition of a book that was published in 1967. The book first deals with the nature of agricultural risks and their insurability. The second part describes the principles and practices of the main types of insurance currently applied to agriculture in different countries. The third and last part is a critical examination of the applicability of the techniques of crop and livestock insurance so far evolved in developed countries to developing countries, and also the possibilities of international reinsurance of national crop insurance systems.

  • Anatomy and Human Movement

    Structure and Function
    • 1st Edition
    • Nigel Palastanga + 2 more
    • English
    Anatomy and Human Movement: Structure and Function describes the musculoskeletal structures of the human body and the biomechanics behind their movements. The book provides anatomical descriptions of bone and muscle groups with emphasis on the joints; enumeration of common traumatic or pathological problems affecting the musculoskeletal structures; and the use of palpation through intact skin to describe the structures, as well as how movements can be tested and analyzed with respect to joint movement, muscle work and function. Chapters on embryology; the skin and its appendages; terminologies used in the book; and an account of the structure and function of the nervous system are included as well. Students of anatomy will find the text a valuable reference material.

  • Pulsatility in Neuroendocrine Systems

    • 1st Edition
    • Volume 20
    • Jon E. Levine + 1 more
    • English
    Pulsatility is now recognized as a nearly ubiquitous functional feature of neuroendocrine systems. This volume presents a comprehensive guide to the established and emerging technologies being used to study the perplexing phenomenon of pulsatility. Molecular, cellular, physiological, and mathematical approaches are described in detail.

  • Advances in Metabolic Disorders

    Volume 2
    • 1st Edition
    • Rachmiel Levine + 1 more
    • English
    Advances in Metabolic Disorders discusses the uric acid and gout, the macroglobulins, the metabolism of testosterone in feminizing testes, tryptophan metabolism, and anabolic steroids. It defines the concept of nitrogen-retaining steroids and their use in disease. The book also explains the meaning of macroglobulinemia. The text examines the genetic factors in the development of gout. The technology involved in the control of purine synthesis is analyzed. The nucleotide degradation and uric acid synthesis are explained. The accumulation of uric acid in gout is discussed in detail. The formation of renal stone is explored. A chapter of the book focuses on a group of antibody molecules. This chapter also introduces cytology, hematology, and serology. A section of the volume is devoted to the source of macroglobulins, chromosomal aberrations, the analysis of urinary metabolites and the nature of macroglobulinemia. The book will provide useful information to doctors, students, and researchers in the field of medicine.

  • Soil Fungi and Soil Fertility

    An Introduction to Soil Mycology
    • 2nd Edition
    • S. D. Garrett
    • English
    Soil Fungi and Soil Fertility, Second Edition is an introduction to soil microbiology, incorporating significant advances in knowledge and understanding of the way micro-organisms live and function under laboratory and natural conditions. This book is comprised of nine chapters, discusses soil microbiology, and shows how the living ecosystem of the soil helps maintain soil fertility and crop production. This text begins with a description of the soil as a habitat, encompassing both its physical and chemical characteristics. The root systems, soil fauna, and soil micro-organisms or the Protist Kingdom all form the living inhabitants of the soil. The components of soil fungi from the organization and growth of its branching system called mycelium to the asexual reproduction and final dispersion are explained. This book also discusses genetic mechanisms in fungi and nuclear division that is a compensatory reduction in the number of chromosomes back to the haploid number that must occur. This text also presents a comparison of further studies of the fungal communities through microscopic and cultural methods, as well as other methods that would yield better soil fungi and soil fertility. Also considered are factors that affect the competitive saprophytic colonization of substrates by soil fungi, and then how these fungi exploit their colonized substrates for survival. This monograph then examines the root-infecting fungi through their ability to feed on living plant tissues and how a balanced host-parasite relationship actually benefits the fungi community.This book is suitable for soil mycologists, soil researchers, agriculturists, and university undergraduates interested in soil microbiology.

  • Atlas of Human Tumor Cell Lines

    • 1st Edition
    • Robert K.M. Hay + 2 more
    • English
    Human tumor cells in culture are valuable for studying cancer causes and properties. This convenient reference provides useful information for cancer researchers on commonly used, established tumor cell lines of the major human organ systems.Atlas of Human Tumor Cell Lines includes data about morphological, metabolic, genetic, and growth characteristics of human tumor cells, with morphological characteristics presented in more than 250 photomicrographs. It also contains information for establishing and maintaining human tumor cell lines in culture, and each chapter covers future perspectives.

  • Biochemistry and Physiology of Plant Immunity

    • 1st Edition
    • B. A. Rubin + 1 more
    • English
    Biochemistry and Physiology of Plant Immunity details the physiological properties of plant immunity from a biochemical perspective. The book provides a summary and concise explanation of the various studies conducted on the field of biochemistry and physiology of plant immunity. The text first details the evolution of parasitism, and then proceeds to discussing the biochemistry and physiology of heterotrophic micro-organisms. Next, the selection talks about the biochemistry and physiology of diseased plant, before it finally deals with plant immunity. The book will be of great use to researchers and practitioners of disciplines that deal with the health of vegetation, such as botany and horticulture.

  • Studies in Neurolinguistics

    • 1st Edition
    • Haiganoosh Whitaker + 1 more
    • English
    Studies in Neurolinguistics, Volume 3 presents detailed case histories, multi-subject experimental studies, literature reviews, and research papers that employ a variety of experimental and observational techniques. This volume contains seven chapters that focus on a wide range of research in the field of neurolinguistics. Chapter 1 discusses the various approaches to the problem of auditory comprehension in aphasia. A survey of the world's literature on bilingualism and aphasia is provided in chapter 2. The third chapter examines the different models and explanations for conduction aphasia. Chapter 4 provides a synthesis of the anatomic, physiologic, and behavioral research on the role of the limbic system in human communication. Chapter 5 presents a model of individual differences in hemispheric functioning, in which a number of theories about the left and right hemispheres are analyzed and compared. Chapter 6 shows how different levels of language are revealed. The last chapter addresses "The Question of Electrophysiological Asymmetries Preceding Speech" in a study of the readiness potentials over the motor and premotor regions in eight subjects. Linguists, psychologists, and neurologists will find the book highly informative.

  • Neurobiology of Steroids

    • 1st Edition
    • Volume 22
    • P. Michael Conn + 1 more
    • English
    Steroid hormones are unique compounds in that they are active at the interface of peripheral endocrine events and neural mechanisms. Thus their effects present an important peripheral signaling system to alter brain function. This volume presents state-of-the-art and classical techniques for the study of steroid hormones and their receptors and their effects and actions.

  • Endocrine Aspects of Disease Processes

    Proceedings of the Conference Held in Honor of Hans Selye, Mont Tremblant, Quebec
    • 1st Edition
    • Gaëtan Jasmin
    • English
    Endocrine Aspects of Disease Processes presents a critical review of hypothalamic hormones regulating the secretion of the anterior pituitary. The book discusses calcitonin as a hormone of ultimobranchials; the brain monoamines and thyroid hormones on emotional stress induced by sympathomimetic agents; and the pharmacology of aggression. Some of the topics covered in the book are the characteristics of brain plasticity under stress; the sleep-wakefulness patterns; the endocrine factors in the etiology of peptic ulcer; and blood sugar levels and allergies. The inflammation and structure of thymus; the cause of coronary and cerebral artery thrombosis in human; and the definition of serum aminopexy are also considered. The book further tackles corticosterone-bindi... by transcortin; the pituitary-thyroid-ad... interaction in the rat; and the description of polypeptides and biogenic amines in the acute inflammatory reactions. The text also looks into the pathogenesis of adrenal-regeneration and methyl-androstenedio... hypertension; and the peripheral vasodilation and thymic tumors in magnesium-deficient rats. A chapter is devoted to the role of the adrenal cortex in the pathogenesis of a spontaneous hereditary congestive heart failure. The book can provide useful information to endocrinologist, doctors, students, and researchers.

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