Nanotechnology for Drug Delivery and Pharmaceuticals
- 1st Edition - January 10, 2023
- Imprint: Academic Press
- Editors: Ravindra Pratap Singh, Kshitij RB Singh, Jay Singh, Charles Oluwaseun Adetunji
- Language: English
- Paperback ISBN:9 7 8 - 0 - 3 2 3 - 9 5 3 2 5 - 2
- eBook ISBN:9 7 8 - 0 - 3 2 3 - 9 5 3 2 6 - 9
Nanotechnology for Drug Delivery and Pharmaceutical Sciences presents various drug-delivery techniques that utilize nanotechnology for the biomedical domain, highlighting both ther… Read more
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Request a sales quoteNanotechnology for Drug Delivery and Pharmaceutical Sciences presents various drug-delivery techniques that utilize nanotechnology for the biomedical domain, highlighting both therapeutic and diagnostic applications. The book provides important facts and detailed studies on different promising nanocarriers like liposomes, exosomes and virus-based nanocarriers. Moreover, it explores these nanocarriers' utilization in the therapeutic applications of various diseases such as cancer, inflammation, neurodegenerative disorders like Huntington’s disease, Alzheimer's disease, human immunodeficiency virus (HIV), and inflammatory bowel disease. In addition, the book describes how nanotechnology has efficiently overtaken conventional dosage forms and provided comfort and ease to patients.
Relevant information regarding market trends, patents and social-economic factors are also provided, making this the perfect reference for doctors, researchers and scientists working in the fields of medicine, biochemistry, biotechnology, nanobiotechnology and the pharmaceutical sciences.
- Gives a brief description of the utilization of nanotechnology in the drug-delivery domain
- Highlights the properties of nanocarriers, their diagnostic and imaging applications, and their potential role in clinical diagnosis
- Focuses on future developments and possibilities, allowing readers to enhance and explore the remaining gaps
Doctors, researchers, and scientists who are working majorly in the fields of medicine, biochemistry, biotechnology, nanobiotechnology, pharmaceutical sciences, material chemistry, chemistry, zoology, botany, and microbiology
- Cover Image
- Title page
- Table of Contents
- Copyright
- Dedication
- List of contributors
- About the editors
- Preface
- Acknowledgments
- Section 1: Targeted drug delivery
- Chapter 1. Introduction to drug-delivery techniques based on nanotechnological approaches
- Abstract
- Introduction
- Synthesis of nanocarriers and nanomedicines for targeted drug delivery
- Utility of nanocarriers
- Utility of nanomedicines
- Targeted drug delivery
- Pros of nano-based targeted drug delivery
- Toxicity of nanomaterials used for targeted drug delivery applications
- Conclusion
- References
- Chapter 2. Methods of fabricating various nanocarriers for targeted drug delivery
- Abstract
- Introduction
- Various nanocarriers for drug delivery
- Fabrication methods/formulation method of nanocarriers
- Conclusion and prospects
- References
- Chapter 3. Biologically synthesized nanocarriers for targeted drug delivery applications
- Abstract
- Introduction
- Biogenic nanocarriers employed in drug delivery
- Physicochemical properties of nanocarriers for their use in targeted drug delivery systems
- Plant protein–based nanocarriers for targeted drug delivery system
- Smart nanocarriers in clinical interventions and translation for targeted therapies or disease treatments
- Conclusions and future prospects
- References
- Chapter 4. Nanomedicine and nanocarriers for cancer treatment
- Abstract
- Introduction
- Nanotechnology in cancer therapy
- Nanomedicines for cancer treatment
- Nanotechnology to nanomedicine
- Emerging vaccine nanotechnology
- Enhancing drug delivery to the tumor
- Principles involved in the development of nanomedicine
- Opportunities: advanced functionalities
- Tumor targeting via enhanced permeability and retention
- Passive targeting or physical targeting
- Active targeting
- Stimuli-responsive systems/triggered release
- Internally responsive drug delivery
- Externally responsive drug delivery
- Multifunctionality/theranostics
- Antibody-mediated targeting
- Antiangiogenesis
- Nanomedicine in cancer treatment
- Viral nanoparticles for cancer therapy
- Organic nanocarriers for cancer therapy
- Drug conjugates
- Lipid-based nanocarriers
- Polymer-based nanocarriers
- Inorganic nanoparticles for cancer therapy
- Porous inorganic nanomaterials
- Combination therapy
- Conclusion, challenges, and current limitations
- Barriers in physicochemical studies
- Safety concern
- Regulatory issues
- Scale-up and manufacturing issues
- Immunological challenges of nanomedicines
- References
- Chapter 5. Role of nanocarriers for inflammation treatment
- Abstract
- Introduction
- Overview of inflammatory conditions and treatments
- Anti-inflammatory treatment with a nanoparticle-based drug delivery system
- Treatment of inflammatory diseases using nanoparticles
- Clinical trials
- Future prospects and conclusions
- Acknowledgment
- References
- Further reading
- Chapter 6. Nanodiagnostics and nanomedicines for neurodegenerative disorders
- Abstract
- Introduction
- Etiopathogenesis and pharmacology of neurodegenerative disorders
- Nanodiagnostics and manomedicines for neurodegenerative diseases
- Translational nanodiagnostics and nanomedicine-based products for neurodegenerative diseases
- Conclusion
- References
- Chapter 7. Potentialities of nanomedicine and nanocarriers for infectious disease treatment
- Abstract
- Introduction
- Different types of infectious diseases
- Conventional versus modern approaches
- Nanotechnology approaches against microbial resistance
- Nanotechnology potential in drug delivery
- Nanocarrier-mediated treatment strategies
- Sustained systemic delivery
- Targeted medication delivery through receptors (active) and stimuli
- Local delivery
- Strategies used to treat infectious diseases
- Antibacterial nanoparticles against planktonic bacteria
- Antibacterial nanoparticles against biofilm bacteria
- Antibacterial nanoparticles against intracellular bacteria
- Animal-based evaluation of antibacterial nanoparticles
- Virus-based nanoparticles
- Nanoparticles derived from fungal pathogens
- Nanoparticles mimicking mammalian cells
- Conclusion and perspectives
- Acknowledgments
- References
- Chapter 8. Recent plant-based nanomedicine and nanocarrier for cancer treatment
- Abstract
- Introduction
- Advancement in plant-based nanocarrier systems for cancer treatment
- Different plant-based nanocarrier systems for the treatment of cancer
- Plant-based compounds used in cancer therapy
- Future prospects and barriers of nanomaterials for cancer therapy
- Conclusion
- Acknowledgment
- References
- Chapter 9. Utility of nanomedicine and nanocarriers for noninfectious disease treatment
- Abstract
- Introduction
- Chemistry and mechanism of action for nanomedicine and nanocarriers for noninfectious disease treatment
- Nanotechnology in central nervous system diseases
- Nanotherapies for central nervous system disease
- Nanotechnology in diabetes
- Nanotechnology in respiratory diseases
- Nanomaterials in treatment of autoimmune diseases
- Nanocarriers for targeted therapy in cancer treatment
- The application of nanomaterials in vaccine design including COVID-19 vaccines
- Conclusion and prospects
- Acknowledgment
- References
- Chapter 10. Passive and active targeted drug delivery strategies
- Abstract
- Introduction
- Passive targeted drug delivery
- Physiochemical properties of nanocarriers
- Active targeted drug delivery
- Conclusion
- References
- Chapter 11. Utility of various drug delivery systems and their advantages and disadvantages
- Abstract
- Introduction
- Nanoparticles as therapeutic administration platforms
- Comparison of Various Nanocarrier Systems
- Classification on the basis of administration routes
- Hazards of nanomedicines
- Future tendencies for nanocarriers in drug distribution
- Conclusion
- References
- Chapter 12. Clinical applications and future clinical trials of the drug delivery system
- Abstract
- Introduction
- Clinical applications
- Transdermal patches
- Pulmonary drug delivery systems
- Implantable systems
- Future clinical trials
- Conclusion
- References
- Chapter 13. Advantages of nanodrug targeting than conventional dosage system
- Abstract
- Introduction
- Administration of drugs
- Conventional dosage systems
- Drug delivery systems
- Smart drug delivery systems
- Polymers
- Porous nanostructures
- Graphene–quantum dots
- Therapeutic proteins delivery
- Advantages of the drug delivery systems
- Drug delivery systems evolution to micro/nanorobots
- Conclusion
- Future of nanomedicine and drug delivery systems
- References
- Chapter 14. Risk assessment of various nanomaterials: health safety perspective
- Abstract
- Introduction
- Exposure assessment to nanoparticles
- Risk characterization of nanoparticles in suspension
- Nonspecific measure
- Specific measure
- Nanotoxicity toward bacteria
- Associated health risks
- Ecotoxicity
- Regulation and challenges
- Conclusion and future perspectives
- Acknowledgment
- References
- Section 2: Pharmaceuticals
- Chapter 15. Introduction to nanotechnological utility in the pharmaceutical industry
- Abstract
- Introduction
- Nanotechnological utility in the pharmaceutical industry
- Recent developments in the pharmaceutical industry
- Role of pharmaceutical nanoparticles
- Advantages
- Disadvantages
- Synthesis
- Patents and market trends of nano-based pharmaceutical products
- Safety and legal factors
- Conclusion and prospects
- References
- Chapter 16. Recent development in the pharmaceutical industries
- Abstract
- Introduction
- Development of new drugs
- Development of drug delivery systems
- Development of drug carrier systems
- Oral delivery
- Gene therapeutics
- Tissue engineering: the development of a novel composite bone substitute
- Recent nanocarrier approaches for targeted drug delivery in cancer therapy
- Conclusion
- References
- Chapter 17. Strategies to synthesize, advantages, and disadvantages of pharmaceutical nanoparticles
- Abstract
- Introduction
- Pharmaceutical nanoparticles-based drug designing and drug delivery process and mechanism
- Synthesis of pharmaceutical nanomaterials, advantages, and disadvantages
- Applications of pharmaceutical nanoparticles
- The role of pharmaceutical nanoparticles in drug delivery formulations
- Features of pharmaceutical nanoparticles-based drug delivery
- Conclusion
- References
- Chapter 18. Recent patents and market trends of nano-based pharmaceutical products
- Abstract
- Introduction
- Patent analysis
- Technology domain distributions
- Market trends and future perspectives
- Acknowledgments
- References
- Chapter 19. Perspectives, safety issues, and legal factors of nano-based materials utility in pharmaceutical applications
- Abstract
- Introduction
- Figure and facts of nanomedicine market
- Nanodrug design and therapeutics
- Nanomedicines in pharmaceutical industries
- Safety issues related to nanomedicines
- Perspectives
- Conclusion
- Acknowledgment
- References
- Index
- Edition: 1
- Published: January 10, 2023
- Imprint: Academic Press
- No. of pages: 472
- Language: English
- Paperback ISBN: 9780323953252
- eBook ISBN: 9780323953269
RP
Ravindra Pratap Singh
Dr. Singh received his B. Sc. from Allahabad University India and his M.Sc and Ph.D. in Biochemistry from Lucknow University, India. He is currently working as an Assistant Professor in the Department of Biotechnology, Indira Gandhi National Tribal University, India. His work and research interests include biochemistry, biosensors, nanobiotechnology, electrochemistry, material sciences, and biosensors applications in biomedical, environmental, agricultural and forensics sciences.
Affiliations and expertise
Assistant Professor in the Department of Biotechnology, Indira Gandhi National Tribal University, IndiaKR
Kshitij RB Singh
Kshitij RB Singh obtained his MSc in Biotechnology from Indira Gandhi National Tribal University, India. Currently, he is a doctoral student in the laboratory of Professor Shyam S. Pandey at the Department of Life Science and Systems Engineering, Kyushu Institute of Technology, Japan. His research interests encompass a range of fields, including biotechnology, biochemistry, nanotechnology, nanobiotechnology, biosensors, and materials sciences.
Affiliations and expertise
Research Scholar at the Graduate School of Life Science and Systems Engineering, Kyushu Institute of Technology, Fukuoka, Japan.JS
Jay Singh
Dr. Jay is an Assistant Professor at the Department of Chemistry, Institute of Sciences, Banaras Hindu University, India, since 2017. He received his Ph.D. degree in Polymer Science from Motilal Nehru National Institute of Technology in 2010 and did MSc and BSc from Allahabad University, India. He is actively engaged in the development of nanomaterials (CeO2, NiO, rare-earth metal oxide, Ni, Nife2O4, Cu2O, Graphene, RGO etc.), based nanobiocomposite, conducting polymer and self-assembled monolayers based clinically important biosensors for estimation of bioanalaytes such as cholesterol, xanthine, glucose, pathogens and pesticides/toxins using DNA and antibodies. He is actively engaged in fabricating metal oxide-based biosensors for clinical diagnosis, food packaging applications, drug delivery, and tissue engineering applications.
Affiliations and expertise
Assistant Professor at the Department of Chemistry, Institute of Sciences, Banaras Hindu University, IndiaCA
Charles Oluwaseun Adetunji
Prof. Charles Oluwaseun Adetunji is a full Professor at the Department of Microbiology, Faculty of Sciences and the Director of Research and Innovation, Edo State University Uzairue (EDSU), Edo State, Nigeria. He formerly served as the Acting Director of Intellectual Property and Technology Transfer, Head of the Department of Microbiology, and Sub Dean of the Faculty of Science. Currently, he holds the positions of Chairman of the Grant Committee and Dean of the Faculty of Science at EDSU.
Prof. Adetunji is a Fellow of the Royal Society of Biology in the UK. Additionally, he serves as a Visiting Professor and the Executive Director of the Center for Biotechnology at Precious Cornerstone University, Nigeria. His research centers on applying biological techniques and microbial bioprocesses to achieve Sustainable Development Goals (SDGs) and contribute to advancements in agriculture.
Affiliations and expertise
Full Professor and Lecturer in the Microbiology Department at Faculty of Sciences, Edo State University Uzairue (EDSU), NigeriaRead Nanotechnology for Drug Delivery and Pharmaceuticals on ScienceDirect