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    • Intelligent Computing Techniques in Biomedical Imaging

      • 1st Edition
      • August 23, 2024
      • Bikesh Kumar Singh + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 9 9 9 2
      • eBook
        9 7 8 0 4 4 3 1 6 0 0 0 4
      Intelligent Computing Techniques in Biomedical Imaging: Methods, Case Studies, and Applications provides comprehensive and state-of-the-art applications of Computational Intelligence techniques used in biomedical image analysis for disease detection and diagnosis. The book offers readers a stepwise approach from fundamental to advanced techniques using real-life medical examples and tutorials. The editors have divided the book into five sections, from prerequisites to case studies. Section I presents the prerequisites, where the reader will find fundamental concepts needed for advanced topics covered later in this book. This primarily includes a thorough introduction to Artificial Intelligence, probability theory and statistical learning. The second section covers Computational Intelligence methods for medical image acquisition and pre-processing for biomedical images. In this section, readers will find AI applied to conventional and advanced biomedical imaging modalities such as X-rays, CT scan, MRI, Mammography, Ultrasound, MR Spectroscopy, Positron Emission Tomography (PET), Ultrasound Elastography, Optical Coherence Tomography (OCT), Functional MRI, Hybrid Modalities, as well as pre-processing topics such as medical image enhancement, segmentation, and compression. Section III covers description and representation of medical images. Here the reader will find various categories of features and their relevance in different medical imaging tasks. This section also discusses feature selection techniques based on filter method, wrapper method, embedded method, and more. The fourth section covers Computational Intelligence techniques used for medical image classification, including Artificial Neural Networks, Support Vector Machines, Decision Trees, Nearest Neighbor Classifiers, Random Forest, clustering, extreme learning, Convolution Neural Networks (CNN), and Recurrent Neural Networks. This section also includes a discussion of computer aided diagnosis and performance evaluation in radiology. The final section of Intelligent Computing Techniques in Biomedical Imaging provides readers with a wealth of real-world Case Studies for Computational Intelligence techniques in applications such as neuro-developmental disorders, brain tumor detection, breast cancer detection, bone fracture detection, pulmonary imaging, thyroid disorders, imaging technologies in dentistry, diagnosis of ocular diseases, cardiovascular imaging, and multimodal imaging.

    • Epigenetic Regulation of Cancer-Part C

      • 1st Edition
      • Volume 387
      • August 23, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 1 4 4 6 2
      • eBook
        9 7 8 0 4 4 3 2 1 5 4 7 6
      Epigenetic Regulation of Cancer, Part C, Volume 389 in the International Review of Cell and Molecular Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of hot topics, including Epigenetic biomarkers in breast cancer, Contribution of epigenetics to virus-driven cancer, Cancer metabolism and epigenetics, Technologies for epigenome editing, Epigenetics and cancer stemness, Epigenetic modifications in obesity-associated cancers, Epigenetics in cf microRNA in blood of solid tumors, Integrative analysis of transcriptome, chromatin accessibility, cell surface antigen in single cell level for AML, and more.Additional chapters cover Epigenetics in lung cancer, Gene Regulatory Mechanisms underlying therapy resistance in Cancer, Role of miRNAs as epigenetic regulators of immune checkpoints in cancer immunity, Epigenetic contributions to Acute myeloid leukemia (AML), Contribution of epigenetics to chemoresistance, Epigenetic contribution to the relationship between obesity and cancer, and Epigenetic regulation in ovarian cancer.

    • Linseed

      • 1st Edition
      • August 22, 2024
      • Sapna Langyan + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 3 1 5 4 3 9 3
      • eBook
        9 7 8 0 4 4 3 1 5 4 4 0 9
      Linseed: A Multipurpose-Multise... Crop of Industrial Significance provides a general overview of linseed as a multipurpose-multise... crop for obtaining a number of valuable products. The book's sections present the use of linseed as food products and discuss a number of important topics, including genetic engineering and breeding advances, pre-harvest processing methods, advanced extraction and quality assessment, metabolic engineering, bioactivity, new food product development, chemistry, and functionality. The book also covers the use of linseed in the textile sector and modified linseed oil products, animal feed products, cosmetics, and personal use products, along with their industrial significance.Food waste and the challenges of linseed crop production and processing into a number of industrial products are also discussed. This book acts as a comprehensive resource for food scientists, researchers, scholars, and industrial people related to food, nutraceutical, cosmetics, pharmaceuticals, textiles, and health practitioners, especially dieticians and nutritionists.

    • TRP Channels as Therapeutic Targets

      • 2nd Edition
      • August 22, 2024
      • Arpad Szallasi
      • English
      • Hardback
        9 7 8 0 4 4 3 1 8 6 5 3 0
      • eBook
        9 7 8 0 4 4 3 1 8 6 5 4 7
      TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use, Second Edition is a comprehensive reference on the roles of TRP Channels in health and disease states. Chapters are completely updated, withe new topics on TRP channels biology, the crystalline structure of TRP channels, targeting TRP channels for pain relief, the relationship with migraine, emerging pain targets, a comprehensive view of the role of TRP channels in respiratory diseases and COVID complications, anxiety relief, renal disease, arthritis, and therapeutic opportunities for thermal regulation. This is a great reference for broad segments of the scientific and medical community. Researchers working on TRP channel drug discovery will benefit from the overview of applications to conditions in specific organ systems. Clinicians interested in new drugs in the pipeline will also find this book helpful for biologic principles of action.

    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 123
      • August 22, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 7 0 6 9
      • eBook
        9 7 8 0 4 4 3 2 9 7 0 7 6
      Advances in Clinical Chemistry, Volume 123, the latest installment in this internationally acclaimed series, contains chapters authored by world-renowned clinical laboratory scientists, physicians, and research scientists.

    • Vesicle Trafficking in Eukaryotes

      • 1st Edition
      • Volume 93
      • August 22, 2024
      • English
      • Hardback
        9 7 8 0 4 4 3 2 9 4 5 8 7
      • eBook
        9 7 8 0 4 4 3 2 9 4 5 9 4
      Current Topics in Membranes, Volume 93 highlights new advances in the field, with this new volume presenting interesting chapters on a variety of topics, including Receptor-mediated endocytosis in kidney cells during physiological and pathological conditions, Membrane transport and endocytosis in malaria parasites, Impact of Coat Protein on Evolution of Ilarviruses, and Membrane Contact Sites.

    • Applied Multivariate Statistical Analysis in Medicine

      • 1st Edition
      • August 21, 2024
      • Jingmei Jiang
      • English
      • Paperback
        9 7 8 0 4 4 3 2 3 5 8 7 0
      • eBook
        9 7 8 0 4 4 3 2 3 5 8 8 7
      Applied Multivariate Statistical Analysis in Medicine provides a multivariate conceptual framework that allows readers to understand the interconnectivity and interrelations among variables, which maintains the intrinsic precision of statistical theories. With a strong focus on the fundamental concepts of multivariate statistical analysis, the book also gives insight into the applications of multivariate distribution in biomedical fields. In 14 chapters, Applied Multivariate Statistical Analysis in Medicine covers the main topics of multivariate analysis methods widely used in health science research. The content is organized progressively from fundamental concepts to sophisticated methods. It begins with basic descriptive statistics in multivariate analysis and follows with parameter estimation, in addition to the hypothesis testing of a multivariate normal distribution, which has heavy applications in biomedical fields where the relationships among approximately normal variables are of great interest. Keeping mathematics to a minimum, considerable emphasis is placed on explanations and real-world applications of core principles to maintain a good balance between introducing theory and cultivating problem-solving skills. This book is a very valuable reference text for clinicians, medical researchers, and other researchers across medical and biomedical disciplines, all of whom confront increasingly complex statistical methods during the analysis and presentation of their results.

    • Principles of Immunotherapy in Breast and Gastrointestinal Cancers

      • 1st Edition
      • August 20, 2024
      • Michele Ghidini
      • English
      • Hardback
        9 7 8 0 4 4 3 1 3 3 7 6 3
      • eBook
        9 7 8 0 4 4 3 1 3 3 7 5 6
      Principles of Immunotherapy in Breast and Gastrointestinal Cancers: Activity, Mechanisms of Resistance, and New Sensitization Strategies presents updated research findings on immunotherapy, with a special focus on the mechanisms of resistance of those cancer types and how to overcome them.The book discusses topics such as tumor cell-intrinsic and -extrinsic mechanisms of cancer resistance to immunotherapy; the role of currently available biomarkers; strategies to overcome therapeutic resistance; sensitizing agents for cancer resistance to cell-mediated immunotherapy; and immunotherapeutic approaches, mechanisms of resistance, and sensitizing strategies in gastroesophageal and biliopancreatic tumors and colorectal cancer.It is a valuable resource for researchers, students, and members of the biomedical and medical fields who want to learn more about resistance to immunotherapy and how to overcome it.

    • Neurologic Channelopathies

      • 1st Edition
      • Volume 203
      • August 20, 2024
      • English
      • Hardback
        9 7 8 0 3 2 3 9 0 8 2 0 7
      • eBook
        9 7 8 0 3 2 3 9 0 8 2 1 4
      Neurological Channelopathies, Volume 203 begins with an introductory overview highlighting common mechanistic themes that cut across different CNS and PNS presentations, but that also have potential for common treatment approaches, considering classification, genetics, and fundamental physiology of ion channels. Subsequent chapters present a detailed consideration of all genetic and immunological channelopathies. Each chapter considers Pathophysiological underpinnings - genetic or immunological; Clinical presentations; Diagnostic approach; and Treatment and management.In the last 15 years, a combination of detailed clinical, genetic, molecular electrophysiological... and immunological research has combined to result in a deep understanding of a subgroup of neurological diseases spanning the central and peripheral nervous system and which have become known collectively as the Neurological Channelopathies. Although it was originally considered that significant ion channel dysfunction would not be compatible with life, we now know this is often not the case, although severe disease can often be the result. Given these major advances, it is now the right time to combine this knowledge into a single HCN volume dedicated to the topics at hand.

    • Imagerie des urgences neuroradiologiques

      • 1st Edition
      • August 20, 2024
      • François Cotton
      • French
      • Paperback
        9 7 8 2 2 9 4 7 8 6 2 8 0
      • eBook
        9 7 8 2 2 9 4 7 8 6 7 8 5
      La survenue brutale d’un déficit neurologique oriente toujours vers la réalisation en urgence d’une imagerie du système nerveux central par scanner ou IRM. Cet examen est crucial pour la prise en charge thérapeutique du patient. Ce nouveau volume de la collection des « Syllabus de la SFR »(Société française de radiologie) et de la SFNR (Société française de neuroradiologie) propose ainsi un état de l’art de l’imagerie des urgences neuroradiologiques.C... ouvrage propose toute la sémiologie à connaître afin de pouvoir proposer la gamme diagnostique des urgences à rechercher. Il donne les clés pour privilégier la technique d’exploration la plus pertinente. Après un rappel des protocoles d’exploration en fonction des urgences, ou encore des éléments en vue de mieux comprendre la neuroradiologie interventionnelle, sont ainsi évoqués, entre autres, les accidents vasculaires cérébraux, les urgences traumatiques, infectieuses, métaboliques et toxiques, celles en fonction des régions (médullaire, orbitaire, etc.) ou en fonction des traitements sans oublier les spécificités pédiatriques, gériatriques et psychiatriques.Riche... illustré et complet, présenté de façon didactique et rédigé par les meilleurs experts en neuro-imagerie diagnostique et interventionnelle, cet ouvrage constitue la référence actuelle sur le sujet. Il est indispensable pour tous les radiologues confrontés aux urgences neuroradiologiques (vacations scanners ou IRM, permanence des soins, télémédecine) ainsi que pour les neurologues et neurochirurgiens qui prennent en charge ces patients.

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