Life sciences print books and ebooks | Elsevier

Nanoparticles Synthesis by Soil Microbes

1st Edition
October 21, 2024
Ajay Kumar + 3 more
English
Paperback
9 7 8 0 4 4 3 2 1 6 9 2 3
eBook
9 7 8 0 4 4 3 2 1 6 9 3 0

Nanoparticles Synthesis by Soil Microbes: Application in Plant Production and the Environment, a volume in the Plant and Soil Microbiome series, presents an advanced and recent description of plant and soil microbiome in the nanoparticle synthesis and their application in sustainable agriculture and environment. In The book covers the broad aspect of microbial synthesized nanoparticles in their synthesis and application in sustainable agriculture and environmental management in line with the recent and timely further interest in the biogenic synthesis of nanoparticles due to their environmentally-frie... cost-effective, rapid, and efficient nature.The microbial cell contains various bioactive compounds, and in the last few years, nanoparticle syntheses from the microbial cell have been increasingly sought due to their overall cost effectiveness and less toxic residual products. Microbe-assisted synthesis of nanoparticles could provide a green, environmentally benign, rapid and efficient route for the fabrication of biocompatible nanostructures with diverse physical-chemical and optoelectronic properties.

Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders

1st Edition
October 21, 2024
Gabriele De Rubis + 5 more
English
Paperback
9 7 8 0 4 4 3 2 7 3 4 5 2
eBook
9 7 8 0 4 4 3 2 7 3 4 4 5

Technological Advances and Innovations in the Treatment of Chronic Respiratory Disorders focuses on 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling. The book, written by a team of leading experts in the field, is an essential resource for anyone interested in the future of CRD treatment. Chapters discuss the emerging therapeutic approaches for CRDs, including biologicals and phytoceuticals. Core chapters of the book then cover the application of 3D printing, bioprinting, microfluidics, organ-on-a-chip systems, and molecular modeling to different CRDs. The book concludes with a discussion of the current clinical trials and future prospects for the management of CRDs.This is a valuable resource for researchers, clinicians, and other healthcare professionals who are interested in the latest technological advances in the field of CRDs. It will also be of interest to students and scientists working in the fields of pharmaceutical sciences, microfluidics, bioinformatics, drug design, drug delivery, and 3D printing.

Small Lungs and Obstructed Airways

1st Edition
October 21, 2024
Peter Burney
English
Paperback
9 7 8 0 4 4 3 1 3 9 2 2 2
eBook
9 7 8 0 4 4 3 1 3 9 2 1 5

Small Lungs and Obstructed Airways: Reassessing Chronic Obstructive Pulmonary Disease proposes an alternative perspective to current explanations for the distribution of chronic lung disease. The book considers the link between chronic respiratory disease and associated mortality with smaller lungs rather than obstructed airways and explores other factors contributing to poor lung health besides the current emphasis on the roles of air pollution, occupational exposures, and cardio-metabolic disease. It presents the findings of the Burden of Obstructive Lung Disease (BOLD) study, sharing new views on the prevalence of obstructive lung disease and risk factors across various global regions. Sections cover decreased lung function, including the prevalent views on the impact of both household and external air pollution, occupational exposure, and the prenatal and postnatal/childhood environment in the etiology of impaired lung function and COPD. The book then moves on to discussions on the impact poverty and nutrition has on lung health, sharing the findings of the BOLD study regarding its effect on lung function and risk of COPD in lower-income countries. The book closes with a chapter outlining the clinical and public health implications of the findings discussed in the book.

The multitasking molecular chaperone Hsp60

1st Edition
October 19, 2024
Francesco Cappello + 2 more
English
Paperback
9 7 8 0 4 4 3 2 3 9 9 6 0
eBook
9 7 8 0 4 4 3 2 3 9 9 7 7

The Multitasking Molecular Chaperone Hsp60: Structure, Function, and Impact on Health and Disease provides an overview of this key component of the Chaperone System (CS). The book covers various areas of medicine in which Hsp60 chaperonopathies have been identified. Various chapters discuss the Hsp60 structure, localization, functions, and participation in disease mechanisms both genetic and acquired, focusing on humans but also presenting data obtained from pro- and eukaryotic experimental models. The main goal is to provide information accessible to all healthcare professionals in a way that can be understood by nonspecialists and that would stimulate clinical and pathological detection of Hsp60 chaperonopathies.Mol... mechanisms are briefly described with the purpose of illuminating roads toward accurate diagnosis, treatment, and patient monitoring. Consequently, the possibility of developing/applying chaperonotherapy centered on Hsp60, as a therapeutic tool or target, is analyzed in many sections of this book, across a variety of medical specialties. Over the last several years, the importance of the CS as a physiological system has been brought to prominence and its roles in health and disease made clear. The molecular chaperones, including Hsp60, are the key components of the CS that are typically cytoprotective, but they can also be etiopathogenic factors, causing diseases named chaperonopathies.

Rhizomicrobiome in Sustainable Agriculture and Environment

1st Edition
October 18, 2024
Joginder Singh Panwar + 1 more
English
Paperback
9 7 8 0 4 4 3 2 3 6 9 1 4
eBook
9 7 8 0 4 4 3 2 3 6 9 2 1

Rhizomicrobiome in Sustainable Agriculture and Environment explores the important potential of biocontrol agents in the reduction of overexploitation of synthetic pesticides, enhancing crop production, and maintaining the natural texture and health of agricultural soils. As concerns about sustainable production challenge current practices, this book presents opportunities for utilizing biological systems as part of the solution. Written by a team of global experts, sections explore the full range of rhizomicrobiome topics, including sustainable agriculture, food security, and environmental management. This will be a valuable resource for researchers, academics, and advanced students.Rhizomicrob... is a significant part of plant biological system which impacts the plant growth and survival in different physiological conditions. Its composition includes different microbial networks whose presence is mainly impacted by the root exudates. Archaea, bacteria, protozoa, fungi, oomycetes, nematodes, microarthropods etc. are the significant parts of the rhizomicrobiome. Rhizomicrobiome could be that novel ecosystem housing the bioinoculants that can help create sustainable, productive growth environments.

Drug Discovery Stories

1st Edition
October 18, 2024
Bin Yu + 1 more
English
Paperback
9 7 8 0 4 4 3 2 3 9 3 2 8
eBook
9 7 8 0 4 4 3 2 3 9 3 3 5

Drug Discovery Stories: From Bench to Bedside presents a collection of cases on the development of highly successful pharmaceuticals. It delves into the realm of drug discovery, exploring the structural biology and biological functions of the sought-after targets. The book covers the identification of promising compounds, their transformation from hits to leads through meticulous optimization, and the elucidation of how key compounds interact with the target (in essence, providing invaluable insights for drug design). Additionally, it covers essential information such as the pivotal biological and PK data of lead compounds, any noteworthy clinical results, and a comprehensive overview of other candidate compounds.The field of drug discovery and development has experienced rapid evolution, with numerous new drugs receiving approval each year. While several books have been published on this subject, there is a pressing need for a new book series that accurately reflects the current advancements in drug discovery. This book aims to not only cater to the drug discovery community but also engage other communities involved in chemical biology, synthetic chemistry, and pharmacology.

Sustainable Agriculture under Drought Stress

1st Edition
October 18, 2024
Hassan Etesami + 1 more
English
Paperback
9 7 8 0 4 4 3 2 3 9 5 6 4
eBook
9 7 8 0 4 4 3 2 3 9 5 7 1

Sustainable Agriculture under Drought Stress: Integrated Soil, Water and Nutrient Management seamlessly blends cutting-edge research with practical applications, offering a unique perspective on tackling this urgent challenge. Through a multidisciplinary lens, this book provides a cohesive and comprehensive understanding of both the current landscape and future prospects. Readers will find this book equips them with the knowledge and strategies required to manage soil nutrients and water effectively, ensuring the health of both soil and plants, especially in arid and semi-arid regions, where solutions are urgently needed.This book offers actionable insights into mitigating the impacts of climate change on agricultural systems, making it essential reading for anyone invested in sustainable land management and food security.

γδ T Cell Cancer Immunotherapy

1st Edition
October 17, 2024
Marta Barisa
English
Hardback
9 7 8 0 4 4 3 2 1 7 6 6 1
eBook
9 7 8 0 4 4 3 2 1 7 6 7 8

γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation sets out and critically discusses the current clinical and relevant preclinical γδ T cell immunotherapy landscape.In five chapters, field experts discuss the challenges facing γδ T cell oncoimmunotherapy, propose solutions, and map next steps.Particular attention is given to summarizing our understanding of the complex, translationally relevant human γδ T cell biology, the evidence basis for designing γδ T cell combination trials and data-driven perspectives on what is known—and what isn’t—about γδ T cell therapeutic persistence. Various perspectives are provided on how issues of cytotoxic effector function, functional exhaustion, and cytokine addiction can be mitigated using gene engineering.A chapter is dedicated to the systematic review of all γδ T cell immunotherapy trials to date, and the cell therapy products that were used in these trials. The final chapter discusses allograft persistence-enhancem... techniques in the context of γδ T cell therapy, covering lymphodepleting chemotherapy and synthetic stealth engineering.γδ T Cell Cancer Immunotherapy: Evidence-Based Perspectives for Clinical Translation gives an updated and comprehensive insight into the current state of γδT cell immunotherapy, which is of interest to existing translational γδ T cell specialists, the proliferating range of academic scientists and commercial scientists entering the field, as well as clinicians who may encounter γδ T cell immunotherapy in the clinic, or are wishing to familiarize themselves with noncanonical lymphocyte immunotherapy.

A New Era in Alzheimer's Research

1st Edition
October 17, 2024
Sandeep Kumar Singh + 1 more
English
Paperback
9 7 8 0 4 4 3 1 5 5 4 0 6
eBook
9 7 8 0 4 4 3 1 5 5 3 9 0

A New Era in Alzheimer's Research: Pathogenesis, Prevention, and Treatment is focused on the research and perspectives in Alzheimer's disease (AD), offering an update on the challenging aspects of neurodegenerative disorders. Each chapter of this book contains unique and valuable scientific information on the latest progress of research in neurodevelopmental diseases. Even after years of research, Alzheimer's disease is still far from being cured; this book addresses the most current issues within the many dimensions relevant to the pathogenesis, diagnosis, and prevention under one cover, making it useful for researchers, students, and clinicians, as well as those in pharmaceuticals.

Genome Editing for Neurodegenerative Diseases

1st Edition
October 17, 2024
Sandeep Kumar Singh + 3 more
English
Paperback
9 7 8 0 4 4 3 2 3 8 2 6 0
eBook
9 7 8 0 4 4 3 2 3 8 2 7 7

Genome Editing for Neurodegenerative Diseases: From Concept to Clinical Trials examines recent advances in neurodegenerative disease research and clinical challenges in practical applications. With an emphasis on genome editing tools such as ZFNs, TALENSs and CRISPR-Cas, this book sheds light on the possibilities to counteract genetic and neurodegenerative diseases. It will be of interest to researchers in neuroscience and biopharmaceuticals, as well as clinicians specializing in neurodegenerative diseases.

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