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Elsevier

Books in Life sciences

  • Actinobacteria: Diversity and Biotechnological Applications

    New and Future Developments in Microbial Biotechnology and Bioengineering
    • 1st Edition
    • Bhim Pratap Singh + 2 more
    • English
    Actinobacteria: Diversity and Biotechnological Applications: New and Future Developments in Microbial Biotechnology and Bioengineering, a volume in the series New and Future Developments in Microbial Biotechnology and Bioengineering series, offers the latest on the biotechnology of Kingdom actinobacteria, covering unique niches like their endosphere, rhizospheric soil and contaminated sites, etc. The book also covers the bioactive secondary metabolites obtained from actinobacteria and describes the application of microorganism (Actinobacteria) in plant growth promotion and in environmental cleanup. Finally, the book describes the biocontrol aspects of actinobacteria and how they can control fungal phytopathogens and the production of secondary metabolites.

  • Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle

    • 1st Edition
    • Tetsuya Watanabe
    • English
    Biophysical Basis of Physiology and Calcium Signaling Mechanism in Cardiac and Smooth Muscle acts as a bridge between physiology and physics by discussing the physiology and calcium signaling mechanism in cardiac and smooth muscle. By exploring the mechanism of the cyclic release of stored Ca^(2+) in the SR or ER, this book covers the cell communication system, including excitable cells, recognizing the most relevant mechanisms of cell communication. Serving as a bridge between physiology and physics, coverage spans the physiology and calcium signaling mechanism in cardiac and smooth muscle, offering insight to physiological scientists, pharmaceutical scientists, medical doctors, biologists and physicists.

  • Neurogenetics, Part II

    • 1st Edition
    • Volume 148
    • English
    Neurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses.

  • Sirtuins in Health and Disease

    • 1st Edition
    • Volume 154
    • English
    Sirtuins in Health and Disease, Volume 154 presents the reactions catalyzed by sirtuins in terms of their unique coenzyme NAD+-dependent catalytic mechanisms, the ways to elucidate these mechanisms, and the design of the inhibitory compounds against the sirtuin-catalyzed reactions as potential therapeutic agents for human diseases. Sections cover the concepts and chemical tools in sirtuin research, SIRT4 and SIRT7, the regulatory effects of NAD metabolic pathways on sirtuin activity, sirtuins as modifiers of Huntington’s Disease (HD) pathology, parasite sirtuins as targets for novel chemotherapeutic agents, targeting sirtuins – substrate specificity and inhibitor design, and chemical probes in sirtuin research. This book focuses on the outstanding issues in the sirtuin field and implications for future sirtuin research.

  • Sustainable Recovery and Reutilization of Cereal Processing By-Products

    • 1st Edition
    • Charis M. Galanakis
    • English
    Sustainable Recovery and Reutilization of Cereal Processing By-Products addresses topics associated with the sustainable management of cereal manufacturing. Emphasis is placed on current, advisable practices, general valorization techniques of cereal processing by-products, and the functional properties of healthy cereal by-product components that lead to target applications in foods and nutraceuticals. Focus includes discussions on wheat bran, distillers' dried grains—based within the biorefinery concept, and different techniques for the separation, extraction, recovery and formulation of valuable compounds, including proteins, arabinoxylans, and beta-glucan.

  • Plastid Genome Evolution

    • 1st Edition
    • Volume 85
    • English
    Plastid Genome Evolution, Volume 85 provides a summary of recent research on plastid genome variation and evolution across photosynthetic organisms. It covers topics ranging from the causes and consequences of genomic changes, to the phylogenetic utility of plastomes for resolving relationships across the photosynthetic tree of life. This newly released volume presents thorough, up-to-date information on coevolution between the plastid and nuclear genomes, with chapters on plastid autonomy vs. nuclear control over plastid function, establishment and genetic integration of plastids, plastid genomes in alveolate protists, plastid genomes of glaucophytes, the evolution of the plastid genome in chlorophyte and streptophyte green algae, and more.

  • Protein-Protein Interactions in Human Disease, Part A

    • 1st Edition
    • Volume 110
    • English
    Protein-Protein Interactions in Human Disease, Part A, Volume 110 aims to promote further research and development in the protein interaction network as a means to not only identify the critical proteins involved in the etiology of human diseases, but also identify new protein targets for drug development. Sections cover such topics as protein-protein interaction modulators for epigenetic therapies, intrinsic disorder, protein-protein interactions and disease, targeting protein-protein interactions in the ubiquitin-proteasome pathway, the proteomics of occupational diseases, and computational methods in predicting the impact of SNPs in protein-protein network, amongst other topics.

  • International Review of Cell and Molecular Biology

    • 1st Edition
    • Volume 336
    • English
    International Review of Cell and Molecular Biology. Volume 336 reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. This updated volume includes specific chapters on Membrane trafficking in autophagy, Targeting the metabolism of leukemic cells, Autophagic flux in Alzheimer's disease, Transcriptional alterations associated with celiac disease, and the Regulation of antitumor immunity by IDO1, amongst other timely topics. The articles published in IRCMB have a high impact and an average cited half-life of 9 years. This great resource ranks high amongst scientific journals dealing with cell biology.

  • Advances in Cancer Research

    • 1st Edition
    • Volume 137
    • English
    Advances in Cancer Research, Volume 137, the latest release in this ongoing, well-regarded serial provides invaluable information on the exciting and fast-moving field of cancer research. This volume presents original reviews on research bridging oncology and gene expression, with this volume covering unconventional approaches to modulating the immunogenicity of tumor cells, tumor dormancy and immunoediting, the emerging role of anti-apoptotic Bcl-2 family proteins in chemoresistance, Beclin-1 and autophagy, MDA-7/IL-24, and nanotechnology and medicine.

  • Inmunología básica para medicina

    • 1st Edition
    • Isabel Olazabal Olarreaga + 1 more
    • Spanish
    Manual conciso que destaca la información más útil para el médico y expone los temas de actualidad para estudiantes y profesionales en los fundamentos de la Inmunología. El contenido más importante de la obra es: 24 temas de inmunología básica con información clínica complementaria; 4 anexos sobre patógenos, trasplantes, oncología y vacunas; cuadros con aspectos de interés generales y médicos, así como resúmenes al final de cada capítulo; guías de seminarios para ayudar a integrar conocimientos; material de carácter molecular esencial; profusamente ilustrado, para ayudar a fijar conceptos inmunológicos. Dirigida a estudiantes de Medicina, médicos de cualquier especialidad y estudiantes de otros grados de ciencias de la salud que necesiten ponerse al día en esta materia de una manera breve, clara y desarrollada de forma que se facilita el autoaprendizaje.

  • Food Quality: Balancing Health and Disease

    • 1st Edition
    • Volume 13
    • Alexandru Mihai Grumezescu + 1 more
    • English
    Food Quality: Balancing Health and Disease, Volume Thirteen in the Handbook of Food Bioengineering series, provides essential information for researchers, scientists and students on the relationship between the quality of foods and disease at the biological level. It presents different technological approaches to detect food properties and their capabilities for balancing health and disease to deliver high-quality products to consumers. This volume explores the dynamic potential of how food bioengineering can improve traditional foods through modern methods to make a positive impact on human health and foster innovation.

  • The Nature and Use of Ecotoxicological Evidence

    Natural Science, Statistics, Psychology, and Sociology
    • 1st Edition
    • Michael C. Newman
    • English
    The Nature and Use of Ecotoxicological Evidence: Natural Science, Statistics, Psychology, and Sociology examines how toxicologists and environmental professionals come to understand and make decisions about possible harm from pollutants. Drawing on concepts and techniques from the natural, social and mathematical sciences, the book emphasizes how pollutant-related evidence is gathered, assessed, communicated and applied in decision-making. Each chapter begins with a real-world example before exploring fundamental cognitive, social, statistical or natural science concepts to explain the opening example. Methods from other disciplines for recognizing, reducing or removing the influence of impediments in wise decision-making are highlighted in each chapter. Misreading evidence by the scientific community, and miscommunication to regulators and the public, remain major impediments to wise action in pollution issues. Which evidence comes to dominate the dialogue among scientists, regulators and decision makers depends on social and scientific dynamics. Yet psychological and sociological factors that influence the movement of evidence through scientific communities to regulators receive cursory discussion by professionals unfamiliar with the sociology literature. Toxicologists, environmental scientists, psychologists and professionals and students across the sciences will find the book useful for understanding how evidence is generated, assessed and communicated in their own fields.

  • Skin and Arthropod Vectors

    • 1st Edition
    • Nathalie Boulanger
    • English
    Recent research on skin immunity and the skin microbiome reveals the complexity of the skin and its importance in the development of immunity against arthropod-borne diseases. In diseases such as malaria, borreliosis, leishmaniasis, trypanosomiasis, etc., the skin interface has been shown as an essential site for pathogens to hide from the immune system, and as a potential site of persistence. Only very few vaccines have been successfully developed so far against these diseases, likely because of an insufficient understanding on the development of skin immunity against pathogens. Skin and Arthropod Vectors expands our knowledge on the role of the skin interface during the transmission of arthropod-borne diseases and particularly its immunity. This work may support researchers who strive for developing more efficient diagnostic tools and vaccines. It also gives scientists and advanced students working in related areas a better insight on how humans and animals are attractive to arthropods to develop better repellents, or to set up transgenic arthropods.

  • Apprentices to Genius: A tribute to Solomon H. Snyder

    • 1st Edition
    • Volume 82
    • English
    Apprentices to Genius: A tribute to Solomon H. Snyder, a volume in the Advances in Pharmacology series, presents a tribute to Dr. Solomon H. Snyder, highlighting chapters submitted from a broad range of his students. It covers many different areas of neuroscience and pharmacology, with this volume exploring how receptor binding and drug discovery, the emerging role of glutamate in the pathophysiology of mental illness, nitric oxide signaling in neurodegeneration and cell death, carboxypeptidase E and the identification of novel neuropeptides as potential therapeutic targets, the regulation of mitochondrial functions by TSPO, clozapine and its translational investigation, and more.

  • Fe-S Cluster Enzymes Part B

    • 1st Edition
    • Volume 599
    • English
    Methods in Enzymology, Volume 599 is the second of two volumes focused on Fe-S cluster enzymes. Topics of interest in this new release include steps towards understanding mitochondrial Fe/S cluster biogenesis, iron sulfur clusters in zinc finger proteins, electrochemistry of Iron-sulfur enzymes, NRVS for Fe in biology and its experiment and basic interpretation, methods for studying iron regulatory protein 1, an important protein in human iron metabolism, the characterization of glutaredoxin Fe-S cluster binding interactions using circular dichroism spectroscopy, fluorescent reporters to track Fe-S cluster assembly and transfer reactions, methods for studying the Fe-S cluster containing base excision repair glycosylase MUTYH, and more.

  • Endothelium and Cardiovascular Diseases

    Vascular Biology and Clinical Syndromes
    • 1st Edition
    • Protasio L. Da Luz + 3 more
    • English
    Endothelium and Cardiovascular Diseases: Vascular Biology and Clinical Syndromes provides an in-depth examination of the role of endothelium and endothelial dysfunction in normal vascular function, and in a broad spectrum of clinical syndromes, from atherosclerosis, to cognitive disturbances and eclampsia. The endothelium is a major participant in the pathophysiology of diseases, such as atherosclerosis, diabetes and hypertension, and these entities are responsible for the largest part of cardiovascular mortality and morbidly. Over the last decade major new discoveries and concepts involving the endothelium have come to light. This important reference collects this data in an easy to reference resource. Written by known experts, and covering all aspects of endothelial function in health and disease, this reference represents an assembly of recent knowledge that is essential to both basic investigators and clinicians.

  • Thyroid Hormone

    • 1st Edition
    • Volume 106
    • English
    Thyroid hormone, Volume 106, the latest release in the Vitamins and Hormones series first published in 1943 provides up-to-date information on crystal structures and basic structural studies on neurotrophins and their receptors, neurotrophin functions and the biological actions of neurotrophins related to clinical conditions and disease. This new release focuses on timely topics, including the Nuclear Import and Export of the Thyroid Hormone Receptor, the Thyroid hormone and the white matter of the central nervous system: from development to repair, Thyroid hormone and astrocyte differentiation, and the Molecular Basis of Nongenomic Actions of Thyroid Hormone, amongst other topics.

  • Long Non-coding RNA

    The Dark Side of the Genome
    • 1st Edition
    • Antonin Morillon
    • English
    The dark side of the genome represents vast domains of the genome that are not encoding for proteins – the basic bricks of cellular structure and metabolism. Up to 98% of the human genome is non-coding and produces so-called long non-coding RNA. Some of these non-coding RNA play fundamental roles in cellular identity, cell development and cancer progression. They are now widely studied in many organisms to understand their function. This book reviews this expanding field of research and present the broad functional diversities of those molecules and their putative fundamental and therapeutic roles and develops the recent history of non-coding RNA, their very much debated classification and how they raise a formidable interest for developmental and tumorigenesis biology. Using classical examples and an extensive bibliography, the book illustrates the most studied and attractive examples of these long non-coding RNA, how they interface with epigenetics, genome integrity and expression and what are the current models of their regulatory mechanisms.

  • Soft Computing Based Medical Image Analysis

    • 1st Edition
    • Nilanjan Dey + 3 more
    • English
    Soft Computing Based Medical Image Analysis presents the foremost techniques of soft computing in medical image analysis and processing. It includes image enhancement, segmentation, classification-based soft computing, and their application in diagnostic imaging, as well as an extensive background for the development of intelligent systems based on soft computing used in medical image analysis and processing. The book introduces the theory and concepts of digital image analysis and processing based on soft computing with real-world medical imaging applications. Comparative studies for soft computing based medical imaging techniques and traditional approaches in medicine are addressed, providing flexible and sophisticated application-oriented solutions.

  • Bioactive Seaweeds for Food Applications

    Natural Ingredients for Healthy Diets
    • 1st Edition
    • Yimin Qin
    • English
    Bioactive Seaweed Substances for Functional Food Applications: Natural Ingredients for Healthy Diets presents various types of bioactive seaweed substances and introduces their applications in functional food products. Presenting summaries of the substances derived from seaweed, this book systematically explores new ingredients and the bioactive substances that are both environmentally friendly and highly beneficial to human health. This evidence-based resource offers an abundance of information on the applications of seaweed as a solution to meet an increasing global demand for sustainable food sources. It is an essential reference for anyone involved in seaweed substance research, seaweed processing, and food and health disciplines.

  • Interventional Inflammatory Bowel Disease: Endoscopic Management and Treatment of Complications

    • 1st Edition
    • Bo Shen
    • English
    Interventional Inflammatory Bowel Diseases: Endoscopic Management and Treatment of Complications covers the preparation, principle, techniques, and damage control of complications in endoscopic therapy, providing the ultimate guidance in endoscopic management of IBD. With contributions from a panel of international leading experts in the field, perspectives are included from GI pathologists, GI radiologists, gastroenterologists, advanced endoscopists, IBD specialists and colorectal surgeons. Recommendations from experts are also included within each chapter. By bridging medical and surgical treatment modalities for IBD, this is the perfect reference for GI researchers, medical students, therapeutic GI endoscopists, IBD specialists, surgeons and advanced health care providers.

  • WNT Signaling

    • 1st Edition
    • Volume 153
    • English
    WNT Signaling, Volume 153, the latest release in the Progress in Molecular Biology and Translational Science series, seeks to provide the most topical, informative, and exciting monographs available on a wide variety of research topics related to prions, viruses, bacteria and eukaryotes. The series provides readers with in-depth knowledge of important molecular biological aspects of organismal physiology and function, along with insights into how this knowledge may be applied to understand and ameliorate human disease. Each volume is edited by an internationally recognized expert who selects contributors at the forefront of a field.

  • Precision Medicine and the Reinvention of Human Disease

    • 1st Edition
    • Jules J. Berman
    • English
    Despite what you may have read in the popular press and in social media, Precision Medicine is not devoted to finding unique treatments for individuals, based on analyzing their DNA. To the contrary, the goal of Precision Medicine is to find general treatments that are highly effective for large numbers of individuals who fall into precisely diagnosed groups. We now know that every disease develops over time, through a sequence of defined biological steps, and that these steps may differ among individuals, based on genetic and environmental conditions. We are currently developing rational therapies and preventive measures, based on our precise understanding of the steps leading to the clinical expression of diseases. Precision Medicine and the Reinvention of Human Disease explains the scientific breakthroughs that have changed the way that we understand diseases, and reveals how medical scientists are using this new knowledge to launch a medical revolution.

  • Impact of Nanoscience in the Food Industry

    • 1st Edition
    • Volume 12
    • Alexandru Mihai Grumezescu + 1 more
    • English
    The Impact of Nanoscience in the Food Industry, Volume 12 in The Handbook of Food Bioengineering series, explores how nanoscience applications in food engineering offer an alternative to satisfying current food needs that cannot be fulfilled by natural products. Nanotechnology enables the development of tailored food ingredients and structures to replace products that are difficult to obtain. The book discusses how specialized nano-preservatives, sensors and food degradation and contamination detectors were developed and how they can be introduced in food products without degrading quality or properties of the final product. A valuable resource for food engineering researchers and students alike.

  • Direct versus Indirect Realism

    A Neurophilosophical Debate on Consciousness
    • 1st Edition
    • John R. Smythies + 1 more
    • English
    Direct versus Indirect Realism: A Neurophilosophical Debate on Consciousness brings together leading neuroscientists and philosophers to explain and defend their theories on consciousness. The book offers a one-of-a-kind look at the radically opposing theories concerning the nature of the objects of immediate perception—whether these are distal physical objects or phenomenal experiences in the conscious mind. Each side—neuroscientists and philosophers—offers accessible, comprehensive explanations of their points-of-view, with each side also providing a response to the other that offers a unique approach on opposing positions. It is the only book available that combines thorough discussion of the arguments behind both direct and indirect realism in a single resource, and is required reading for neuroscientists, neurophilosophers, cognitive scientists and anyone interested in conscious perception and the mind-brain connection.

  • Buckwheat Germplasm in the World

    • 1st Edition
    • Meiliang Zhou + 4 more
    • English
    Buckwheat Germplasm in the World offers an overview of this globally important crop, including its general characterization and genetic diversity—particular... in Russia, China, India and Eastern Europe. The book presents the latest research on molecular marker development, genetics and phenotype analysis of new wild buckwheat to examine the nutritional values of this pseudocereal crop. Due to its short growth span, ability to grow at high altitudes and the high quality of its protein content, buckwheat is considered an important crop for addressing global food needs. Ideal for researchers and advanced-level students seeking better understanding of the buckwheat germplasm.

  • Polyphenols: Properties, Recovery, and Applications

    • 1st Edition
    • Charis M. Galanakis
    • English
    Polyphenols: Properties, Recovery, and Applications covers polyphenol properties, health effects and new trends in recovery procedures and applications. Beginning with coverage of the metabolism and health effects of polyphenols, the book then addresses recovery, analysis, processing issues and industrial applications. The book not only connects the properties and health effects of polyphenols with recovery, processing and encapsulation issues, but also explores industrial applications that are affected by these aspects, including both current applications and those under development.

  • Principles of Hormone/Behavior Relations

    • 2nd Edition
    • Donald W. Pfaff + 3 more
    • English
    Principles of Hormone/Behavior Relations, Second Edition, provides an introduction to the underlying principles of endocrine regulation of behavior, a newly emerging area of research within neurobiology and endocrinology. It addresses the properties of hormone/behavior relations, including the influence of family background, timing issues, neuroanatomical features, cellular mechanisms, and the importance of environmental context and evolution. This new edition incorporates critical advances in the field, also including increased coverage of hormonal influences on food intake, and on the cardiovascular system. The addition of entirely new principles provides further coverage of epigenetics and appetite. Thoroughly revised and updated, this book is an ideal resource for neuroscientists and researchers engaging in this rapidly expanding field of study.

  • Genetic Engineering of Horticultural Crops

    • 1st Edition
    • Gyana Ranjan Rout + 1 more
    • English
    Genetic Engineering of Horticultural Crops provides key insights into commercialized crops, their improved productivity, disease and pest resistance, and enhanced nutritional or medicinal benefits. It includes insights into key technologies, such as marker traits identification and genetic traits transfer for increased productivity, examining the latest transgenic advances in a variety of crops and providing foundational information that can be applied to new areas of study. As modern biotechnology has helped to increase crop productivity by introducing novel gene(s) with high quality disease resistance and increased drought tolerance, this is an ideal resource for researchers and industry professionals.

  • Neurogenetics, Part I

    • 1st Edition
    • Volume 147
    • English
    Genetic methodologies are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is evolving rapidly and expected to grow in scope as more disorders are linked to specific genetic markers. Part I covers basic genetic concepts and recurring biological themes, and begins the discussion of movement disorders and neurodevelopmental disorders, leading the way for Part II to cover a combination of neurological, neuromuscular, cerebrovascular, and psychiatric disorders. This volume in the Handbook of Clinical Neurology will provide a comprehensive introduction and reference on neurogenetics for the clinical practitioner and the research neurologist.

  • Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia

    From Research to Bedside
    • 1st Edition
    • Giuseppe Morgia + 1 more
    • English
    Lower Urinary Tract Symptoms and Benign Prostatic Hyperplasia: From Research to Bedside offers full acknowledgment of the basic research of lower urinary tract symptoms (LUTS) and benign prostatic hyperplasia (BPH), also connecting the clinical and practice management of the disease. It provides a full comprehension of LUTS and BPH from several aspects, allowing for a schematic interpretation of the disease and subsequent medical management. Going beyond the guidelines in the field, this title enhances the knowledge of BPH onset, allowing for the advancement of research, beneficial clinical implication and treatment. Perfect for researchers, urologists, pathologists and endocrinologists, this must-have reference provides what is needed to understand LUTS and BPH in one easy to reference place.

  • Exotic Fruits Reference Guide

    • 1st Edition
    • Sueli Rodrigues + 2 more
    • English
    Exotic Fruits Reference Guide is the ultimate, most complete reference work on exotic fruits from around the world. The book focuses on exotic fruit origin, botanical aspects, cultivation and harvest, physiology and biochemistry, chemical composition and nutritional value, including phenolics and antioxidant compounds. This guide is in four-color and contains images of the fruits, in addition to their regional names and geographical locations. Harvest and post-harvest conservation, as well as the potential for industrialization, are also presented as a way of stimulating interest in consumption and large scale production.

  • Neuromodulation

    Comprehensive Textbook of Principles, Technologies, and Therapies
    • 2nd Edition
    • Elliot Krames + 2 more
    • English
    Neuromodulation: Comprehensive Textbook of Principles, Technologies, and Therapies, Second Edition, serves as a comprehensive and in-depth reference textbook covering all aspects of the rapidly growing field of neuromodulation. Since the publication of the first edition seven years ago, there has been an explosion of knowledge in neuromodulation, optogenetics, bioelectronics medicine and brain computer interfacing. Users will find unique discussions of the fundamental principles of neuromodulation and therapies, and how they are applied to the brain, spinal cord, peripheral nerves, autonomic nerves and various organs. The book focuses on comprehensive coverage of spinal cord stimulation, non-interventional and interventional brain stimulation, peripheral nerve stimulation, and the emerging fields of neuromodulation, including optogenetics and bioelectronics medicine.

  • Methods in Extracellular Matrix Biology

    • 1st Edition
    • Volume 143
    • English
    Methods in Extra Cellular Matrix, Volume 142, a new volume in the Methods in Cell Biology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Unique to this updated volume are sections devoted to Elastin, Quantification of collagen and elastin, Fibrillins, Lysyl oxidase, Fibulins, Matrilins, Hyaluronic Acid, Small leucine-rich proteoglycans, Syndecans, Fibronectin, SPARC, Thrombospondins, Tenascins, Collagen IV, Multi-photon analysis of ECM, Cell-derived extracellular matrices, Laminins, Fibrillar Collagens, Imaging ECM in developing embryos, Analysis of Matrix Degradation, Ultrastructural analysis of ECM, Versican and Large proteoglycans, and an ECM crosslink analysis. This series covers a wide array of topics about the extracellular matrix, including an understanding of crucial proteins and glycoproteins components of ECM.

  • Vascular Pharmacology: Cytoskeleton and Extracellular Matrix

    • 1st Edition
    • Volume 81
    • English
    Vascular Pharmacology: Cytoskeleton and Extracellular Matrix, Volume 81, contains the latest information on the vascular cytoskeleton and extracellular matrix that is presented with helpful illustrations and supporting references by prominent scientists and highly-recognized experts in the vascular field. Topics of interest in this new release include Pharmacology of the Vascular Cytoskeleton and Extracellular Matrix, The Dynamic Actin Cytoskeleton in Smooth Muscle, The Role of the Actin Cytoskeleton in the Regulation of Vascular Inflammation, The Smoothelin Family of Proteins and the Smooth Muscle Cell Contractile Apparatus, Smooth Muscle Cytoskeletal Network Regulates Expression of the Profibrotic Genes PAI-1 and CTGF, and more.

  • Food Science and the Culinary Arts

    • 1st Edition
    • Mark Gibson
    • English
    Food Science and the Culinary Arts is a unique reference that incorporates the principles of food and beverage science with practical applications in food preparation and product development. The first part of the book covers the various elements of the chemical processes that occur in the development of food products. It includes exploration of sensory elements, chemistry, and the transfer of energy and heat within the kitchen. The second part looks in detail at the makeup of specific foodstuffs from a scientific perspective, with chapters on meat, fish, vegetables, sugars, chocolate, coffee, and wine and spirits, among others. It provides a complete overview of the food science relevant to culinary students and professionals training to work in the food industry.

  • Handbook of Developmental Neurotoxicology

    • 2nd Edition
    • William Slikker Jr. + 2 more
    • English
    Handbook of Developmental Neurotoxicology, Second Edition, provides a comprehensive view of the fundamental aspects of neurodevelopment, the pathways and agents that affect them, relevant clinical syndromes, and risk assessment procedures for developmental neurotoxicants. The editors and chapter authors are internationally recognized experts whose collaboration heralds a remarkable advance in the field, bridging developmental neuroscience with the principles of neurotoxicology. The book features eight new chapters with newly recruited authors, making it an essential text for students and professionals in toxicology, neurotoxicology, developmental biology, pharmacology, and neuroscience.

  • Metastatic Disease of the Nervous System

    • 1st Edition
    • Volume 149
    • David Schiff + 1 more
    • English
    Metastatic Disease of the Nervous System, Volume 149, begins with an overview of the impact and range of direct neoplastic involvement of the central and peripheral nervous system, comprehensively reviewing all aspects of brain metastases, from clinical, radiological and neuropathological manifestations, to the roles of surgery, radiation, systemic and palliative therapy in their management, and the complications of these interventions. The clinical manifestations, diagnosis and treatment of leptomeningeal, dural, spinal epidural and plexus metastases are also covered in detail.

  • Water Scarcity and Sustainable Agriculture in Semiarid Environment

    Tools, Strategies, and Challenges for Woody Crops
    • 1st Edition
    • Ivan Francisco Garcia Tejero + 1 more
    • English
    Water Scarcity and Sustainable Agriculture in Semiarid Environment: Tools, Strategies and Challenges for Woody Crops explores the complex relationship between water scarcity and climate change, agricultural water-use efficiency, crop-water stress management and modeling water scarcity in woody crops. Understanding these cause- and effect relationships and identifying the most appropriate responses are critical for sustainable crop production. The book focuses on Mediterranean environments to explain how to determine the most appropriate strategy and implement an effective plan; however, core concepts are translational to other regions. Informative for those working in agricultural water management, irrigation and drainage, crop physiology and sustainable agriculture.

  • The Liver

    Oxidative Stress and Dietary Antioxidants
    • 1st Edition
    • Vinood Patel + 1 more
    • English
    The Liver: Oxidative Stress and Dietary Antioxidants takes a novel approach to the science of oxidative stress in liver disease by recognizing that diseases are multifactorial and oxidative stress is a single component. It highlights oxidative stress in relation to other processes, such as apoptosis, cell signaling and receptor mediated responses, and includes the therapeutic usage of natural antioxidants in the diet and food matrix, along with coverage of pharmacological and natural agents designed to counteract oxidative stress. Written for research scientists, gastroenterologists, food scientists, hepatologists and physicians, this trans-disciplinary guide will help advance medical sciences and enable new preventative and treatment strategies.

  • Myogenesis in Development and Disease

    • 1st Edition
    • Volume 126
    • English
    Myogenesis in Development and Disease, Volume 126, the latest volume in the Current Topics in Developmental Biology series, covers major topics of research in myogenesis, with a particular emphasis on regeneration and muscle disease. It includes contributions from an international board of authors, providing a comprehensive set of reviews.

  • Chemical Glycobiology: Monitoring Glycans and Their Interactions

    • 1st Edition
    • Volume 598
    • English
    Chemical Glycobiology, Part B, Volume 598, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. This volume is the second release on chemical glycobiology.

  • Food Neophobia

    Behavioral and Biological Influences
    • 1st Edition
    • Steve Reilly
    • English
    Food Neophobia: Behavioral and Biological Influences brings together academic and applied studies to give a comprehensive overview of this topic in both sensory and consumer science and pediatric psychology. The effects of food neophobia can have a huge impact on children’s lives and an influence across their lifespan. Split into two main sections, the book focuses on both the environmental and biological aspects of food neophobia. It covers social, contextual and psychosocial factors that affect food neophobia. Sensory aspects of food neophobia are covered with chapters on disgust and sensation seeking, and genetic and evolutionary influences are also thoroughly discussed. The book is essential reading for academic researchers studying food neophobia from a sensory, consumer science and psychological perspective. It will also be of value to food product developers, especially those working on products for children. Finally, healthcare professionals treating patients suffering from food neophobia will be able to gain greater insight into this condition.

  • Gut Microbiota

    Interactive Effects on Nutrition and Health
    • 1st Edition
    • Edward Ishiguro + 2 more
    • English
    Gut Microbiota: Interactive Effects on Nutrition and Health focuses on the fascinating intestinal microbiome as it relates to nutrition. The book covers the core science in the microbiome field and draws links between the microbiome and nutrition in medicine. Reflecting the most current state of evidence available in the field, the early chapters introduce key concepts about the microbiome, and the latter focus on the application of the gut microbiome and nutrition science. Both human studies and animal studies (where appropriate) are discussed throughout the work. Addressing topics such as gut microbiota throughout the lifespan, gut microbiota in health and disease, and genetic and environmental influences on gut microbiota, this book will provide scientists and clinicians who have an interest in the microbiome with an understanding of the future potential and limitations of this tool as they strive to make use of evidence-based diet information for the maintenance of good health.

  • Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases

    Overview of Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine
    • 1st Edition
    • Emilija Veljkovic + 7 more
    • English
    Nicotine and Other Tobacco Compounds in Neurodegenerative and Psychiatric Diseases: Epidemiological Data on Smoking and Preclinical and Clinical Data on Nicotine provides a comprehensive summary of the epidemiological data on smoking and several neurological disorders, including Alzheimer’s disease, Parkinson’s disease, Multiple Sclerosis, Tourette’s syndrome, schizophrenia, anxiety, depression and ADHD, as well as preclinical and clinical data on the effects of nicotine. Despite the obvious and undisputed harmful nature of smoking, evidence suggests that some tobacco and tobacco smoke-derived constituents may offer neuroprotective effects, possibly in combinations, rather than individually. This unprecedented book describes the complex relationships between smoking and neurological disease and the bioactive compounds found in tobacco. It provides a comprehensive review of nicotine and other compounds found in tobacco plant, with scientific evidence of neuroprotective and anti-inflammatory effects that may act in conjunction with nicotine to exert neuroprotective effects observed in smokers. By presenting findings beyond harmful cigarette smoke effects, attention can be drawn to individual compounds of tobacco that may serve as inspiration for further therapy development.

  • Forensic Odontology

    Principles and Practice
    • 1st Edition
    • Thomas J. David + 1 more
    • English
    Forensic Odontology: Principles and Practice details the aspects necessary to become an accomplished forensic odontologist, including an illustration of the skills necessary to become an expert witness. The book is ideal for both the experienced and novice forensic odontologist, covering many fields of expertise, including civil and criminal matters. The civil side involves standard of care and personal injury matters, while the criminal side involves not only dental identification, but management of mass fatality incidents, age assessment, child and elder abuse, and bitemark analysis.

  • Handbook of Immunoassay Technologies

    Approaches, Performances, and Applications
    • 1st Edition
    • Sandeep K. Vashist + 1 more
    • English
    Handbook of Immunoassay Technologies: Approaches, Performances, and Applications unravels the role of immunoassays in the biochemical sciences. During the last four decades, a wide range of immunoassays has been developed, ranging from the conventional enzyme-linked immunosorbent assays, to the smartphone-based point-of-care formats. The advances in rapid biochemical procedures, novel biosensing schemes, fully integrated lab-on-a-chip platforms, prolonged biomolecular storage strategies, device miniaturization and interfacing, and emerging smart system technologies equipped with personalized mobile healthcare tools are paving the way to next-generation immunoassays, and are all discussed in this comprehensive text. Immunoassays play a prominent role in clinical diagnostics as they are the eyes of healthcare professionals, helping them make informed clinical decisions via confirmed disease diagnosis, and thus enabling favorable health outcomes. The faster and reliable diagnosis of infections will further control their spread to uninfected persons. Similarly, immunoassays play a prominent role in veterinary diagnostics, food analysis, environmental monitoring, defense and security, and other bioanalytical settings. Therefore, they enable the detection of a plethora of analytes, which includes disease biomarkers, pathogens, drug impurities, environmental contaminants, allergens, food adulterants, drugs of abuse and various biomolecules.

  • Methods in Consumer Research, Volume 2

    Alternative Approaches and Special Applications
    • 1st Edition
    • Gaston Ares + 1 more
    • English
    Methods for Consumer Research, Volume Two: Alternative Approaches and Special Applications brings together world leading experts in global consumer research who provide a fully comprehensive state-of-the-art coverage of emerging methodologies and their innovative application. The book puts consumer research in-context with coverage of immersive techniques and virtual reality, while also looking at health-related Issues in consumer science, including sections on food intake and satiation. Other sections delve into physiological measurements within the context of consumer research and how to design studies for specific populations. In conjunction with the first volume, which covers new approaches to classical methodology, this book is an invaluable reference for academics working in the fields of in-sensory and consumer science, psychology, marketing and nutrition. With examples of the methodology being applied throughout, it serves as a practical guide to research and development managers in both food and non-food companies.

  • Sustainable Food Systems from Agriculture to Industry

    Improving Production and Processing
    • 1st Edition
    • Charis M. Galanakis
    • English
    Sustainable Food Systems from Agriculture to Industry: Improving Production and Processing addresses the principle that food supply needs of the present must be met without compromising the ability of future generations to meet their needs. Responding to sustainability goals requires maximum utilization of all raw materials produced and integration of activities throughout all production-to-consum... stages. This book covers production stage activities to reduce postharvest losses and increase use of by-products streams (waste), food manufacturing and beyond, presenting insights to ensure energy, water and other resources are used efficiently and environmental impacts are minimized. The book presents the latest research and advancements in efficient, cost-effective, and environmentally friendly food production and ways they can be implemented within the food industry. Filling the knowledge gap between understanding and applying these advancements, this team of expert authors from around the globe offer both academic and industry perspectives and a real-world view of the challenges and potential solutions that exist for feeding the world in the future. The book will guide industry professionals and researchers in ways to improve the efficiency and sustainability of food systems.

  • Transcriptional Gene Regulation in Health and Disease

    • 1st Edition
    • Volume 335
    • English
    Transcriptional Gene Regulation in Health and Disease, Volume 335, the latest release in the International Review of Cell and Molecular Biology reviews and details current advances in cell and molecular biology. The IRCMB series has a worldwide readership, maintaining a high standard by publishing invited articles on important and timely topics that are authored by prominent cell and molecular biologists. The articles published in IRCMB have a high impact and an average cited half-life of nine years. This great resource ranks high amongst scientific journals dealing with cell biology.

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