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Books in Life sciences

  • Geriatric Neurology

    • 1st Edition
    • Volume 167
    • English
    Geriatric Neurology, Volume 167, serves as an update on the basic biological and behavioral mechanisms underlying the aging process, with an emphasis on neurological aging and state-of-the-art reviews on our understanding of vascular, cognitive, neurodegenerative and neuropsychiatric diseases in the elderly. Developed with an eye to providing both the basic underpinnings of age-related changes and the clinical information necessary to aid in diagnostics and treatment, the book serves as a useful volume for students, basic and translational scientists, and practicing clinicians on how to understand and treat common neurological disorders in the elderly.
  • Conceptual Breakthroughs in Evolutionary Ecology

    • 1st Edition
    • Laurence Mueller
    • English
    Although biologists recognize evolutionary ecology by name, many only have a limited understanding of its conceptual roots and historical development. Conceptual Breakthroughs in Evolutionary Ecology fills that knowledge gap in a thought-provoking and readable format. Written by a world-renowned evolutionary ecologist, this book embodies a unique blend of expertise in combining theory and experiment, population genetics and ecology. Following an easily-accessible structure, this book encapsulates and chronologizes the history behind evolutionary ecology. It also focuses on the integration of age-structure and density-dependent selection into an understanding of life-history evolution.
  • General Medical Semiology Guide Part II

    • 1st Edition
    • Manuela Stoicescu
    • English
    General Medical Semiology Guide, Part Two is the second volume in a two volume set that provides a comprehensive understanding of medical semiology. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter contains a specific questionnaire of important questions that should be asked of patients in different situations to obtain valuable information that will assist in both medical thinking and in the formulation of diagnoses. Part Two covers topics on how to examine primary and secondary skin lesions, hair changes, nails, lymph nodes, breasts, and more.
  • Perspectives in the Development of Mobile Medical Information Systems

    Life Cycle, Management, Methodological Approach and Application
    • 1st Edition
    • Pantea Keikhosrokiani
    • English
    Perspectives in the Development of Mobile Medical Information Systems: Life Cycle, Management, Methodological Approach and Application discusses System Development Life Cycle (SDLC) thoroughly, focusing on Mobile Healthcare Information Systems (M-HIS). Covering all aspect of M-HIS development, the book moves from modeling, assessment, and design phases towards prototype phase. Topics such as mobile healthcare information system requirements, model identification, user behavior, system analysis and design are all discussed. Additionally, it covers the construction, coding and testing of a new system, and encompasses a discussion on future directions of the field. Based on an existing mobile cardiac emergency system used as a real case throughout the chapters, and unifying and clarifying the various processes and concepts of SDLC for M-HIS, this book is a valuable source for medical informaticians, graduate students and several members of biomedical and medical fields interested in medical information systems.
  • Demystifying the Engineering PhD

    • 1st Edition
    • Monica Cox
    • English
    Demystifying the Engineering Ph.D. explores what it means to be an engineering Ph.D. holder, including insights from engineering professionals working in academia and industry across multiple institute types and companies. Topics covered include motivations for obtaining a Ph.D., the added value of a Ph.D., and career options for Ph.D. holders. The book concludes with recommendations for transforming engineering doctoral education to preparing doctoral students for diverse careers in industry and academia.
  • Precision Medicine for Investigators, Practitioners and Providers

    • 1st Edition
    • Joel Faintuch + 1 more
    • English
    Precision Medicine for Investigators, Practitioners and Providers addresses the needs of investigators by covering the topic as an umbrella concept, from new drug trials to wearable diagnostic devices, and from pediatrics to psychiatry in a manner that is up-to-date and authoritative. Sections include broad coverage of concerning disease groups and ancillary information about techniques, resources and consequences. Moreover, each chapter follows a structured blueprint, so that multiple, essential items are not overlooked. Instead of simply concentrating on a limited number of extensive and pedantic coverages, scholarly diagrams are also included.
  • Wearable Robotics

    Systems and Applications
    • 1st Edition
    • Jacob Rosen
    • English
    Wearable Robotics: Systems and Applications provides a comprehensive overview of the entire field of wearable robotics, including active orthotics (exoskeleton) and active prosthetics for the upper and lower limb and full body. In its two major sections, wearable robotics systems are described from both engineering perspectives and their application in medicine and industry. Systems and applications at various levels of the development cycle are presented, including those that are still under active research and development, systems that are under preliminary or full clinical trials, and those in commercialized products. This book is a great resource for anyone working in this field, including researchers, industry professionals and those who want to use it as a teaching mechanism.
  • General Medical Semiology Guide Part I

    • 1st Edition
    • Manuela Stoicescu
    • English
    General Medical Semiology Guide, Part One is the first part of a two volume set that provides a comprehensive understanding of medical semiology. Highly illustrated with many original images from the author’s daily medical practice, the book highlights all signs of diseases and important semiological maneuvers. Each chapter contains a specific questionnaire of important questions that should be asked of patients in different situations to obtain valuable information that will assist in both medical thinking and in the formulation of diagnoses. This volume covers the face, eyes, thyroid gland, skin, mucoses, and more.
  • Milk Proteins

    From Expression to Food
    • 3rd Edition
    • Mike Boland + 1 more
    • English
    Milk Proteins: From Expression to Food, Third Edition contains contributions from internationally recognized authors from academia and industry. Professionals, academics and graduate students working in any of the dairy-related industries or disciplines will continue to find this updated information valuable to their work. Using a unique "field-to-table" approach, this third edition provides comprehensive coverage of new developments and insights into the entire dairy food chain – from the source, to the nutritional aspects affecting the customer. Containing three new chapters, this new edition continues to present a comprehensive overview of the biology, processing, chemistry, and nutrition of milk proteins and features the latest science and developments. Valuable application-based information is made available through the exploration of the use of milk proteins from industry viewpoints.
  • A Physicochemical Theory of Tip Growth

    • 1st Edition
    • Pierre Pelce
    • English
    A Physicochemical Theory of Tip Growth presents the latest information on experimental observations on living organisms, including unicellular algae, hyphae and neurons. These theories are analogous to the ones developed for the growth of nonliving matter, as already exposed by the author in the book.
  • Innate Immunity

    From Louis Pasteur to Jules Hoffmann
    • 1st Edition
    • Yves Carton
    • English
    Innate immunity is a new branch of immunology, confirmed by three Nobel Prize winners in 2011. It is the first line of defense against pathogens and is in a way the preliminary step of adaptive immunity which occurs later, and only present in vertebrates. This book examines the way in which innate immunity was discovered in invertebrates. As a starting point, it looks at the work of Louis Pasteur on silkworm disease and the findings of Ilya Metchnikov, discoverer of phagocytosis. It also investigates André Paillot, who in 1920 demonstrated the existence of humoral immunity in insects, unrelated to the type of immunity that was initially thought to be present in all vertebrates. Finally, Innate Immunity shows how the group directed by Jules Hoffmann found strong similarities between the innate immunity response of insects and mammals. The discovery of a receptor protein in Drosophila, which is also found in humans, was what led to Jules Hoffmann being awarded the Nobel Prize in 2011.
  • Clinical Precision Medicine

    A Primer
    • 1st Edition
    • Judy S. Crabtree
    • English
    Clinical Precision Medicine: A Primer offers clinicians, researchers and students a practical, up-to-date resource on precision medicine, its evolving technologies, and pathways towards clinical implementation. Early chapters address the fundamentals of molecular biology and gene regulation as they relate to precision medicine, as well as the foundations of heredity and epigenetics. Oncology, an early adopter of precision approaches, is considered with its relationship to genetic variation in drug metabolism, along with tumor immunology and the impact of DNA variation in clinical care. Contributions by Stephanie Kramer, a Clinical Genetic Counselor, also provide current information on prenatal diagnostics and adult genetics that highlight the critical role of genetic counselors in the era of precision medicine.
  • Machine Learning

    Methods and Applications to Brain Disorders
    • 1st Edition
    • Andrea Mechelli + 1 more
    • English
    Machine Learning is an area of artificial intelligence involving the development of algorithms to discover trends and patterns in existing data; this information can then be used to make predictions on new data. A growing number of researchers and clinicians are using machine learning methods to develop and validate tools for assisting the diagnosis and treatment of patients with brain disorders. Machine Learning: Methods and Applications to Brain Disorders provides an up-to-date overview of how these methods can be applied to brain disorders, including both psychiatric and neurological disease. This book is written for a non-technical audience, such as neuroscientists, psychologists, psychiatrists, neurologists and health care practitioners.
  • Applied Genomics and Public Health

    • 1st Edition
    • George P. Patrinos
    • English
    Applied Genomics and Public Health examines the interdisciplinary and growing area of how evidence-based genomic knowledge can be applied to public health, population health, healthcare and health policies. The book gathers experts from a variety of disciplines, including life sciences, social sciences, and health care to develop a comprehensive overview of the field. In addition, the book delves into subjects such as pharmacogenomics, genethics, big data, data translation and analysis, economic evaluation, genomic awareness and education, sociology, pricing and reimbursement, policy measures and economic evaluation in genomic medicine. This book is essential reading for researchers and students exploring applications of genomics to population and public health. In addition, it is ideal for those in the biomedical sciences, medical sociologists, healthcare professionals, nurses, regulatory bodies and health economists interested in learning more about this growing field.
  • Tumor Immunology and Immunotherapy – Molecular Methods

    • 1st Edition
    • Volume 629
    • English
    Tumor Immunology and Immunotherapy – Molecular Methods, Volume 629, the latest release in the Methods in Enzymology series, continues the legacy of this premier serial with quality chapters authored by leaders in the field. Chapters in this release include Droplet digital PCR for measuring circulating tumor-derived DNA, Detection and quantification of cytosolic DNA, Methods to detect endogenous dsRNA induction and recognition, Quantification of eIF2alpha phosphorylation during immunogenic cell death, Assessment of annexin A1 release during immunogenic cell death, Luciferase-assisted detection of extracellular ATP in the course of ICD, The P2X7 receptor: structure and function, and much more.
  • Late Aging Associated Changes in Alcohol Sensitivity, Neurobehavioral Function, and Neuroinflammation

    • 1st Edition
    • Volume 148
    • English
    Late aging associated changes in alcohol sensitivity, neurobehavioral function, and neuroinflammation, Volume 148, the latest release in the International Review of Neurobiology series, highlights new advances in the field, with this new volume presenting interesting chapters on a variety of timely topics. Each chapter is written by an international board of authors.
  • Cingulate Cortex

    • 1st Edition
    • Volume 166
    • English
    Cingulate Cortex, Volume 166 summarizes research on the cingulate cortex, including its structure and function in health and how it is compromised in disease or trauma. Chapters discuss the cingulate organization by region and area, cover its function in consciousness, attention, social cognition and spatial orientation, review neurological disorders with cingulate involvement, including neurodegenerative disorders, movement disorders, Parkinson’s, ADHD, Cognitive impairment, Palsy, Tourette’s Syndrome, chronic pain, seizures, and more. Final sections discuss the relationship between the cingulate cortex, stress and psychiatric disorders. Coverage here includes PTSD, anxiety, depression, and evidence-based treatment for same.
  • Engineering Strategies for Regenerative Medicine

    • 1st Edition
    • Tiago G. Fernandes + 2 more
    • English
    Engineering Strategies for Regenerative Medicine considers how engineering strategies can be applied to accelerate advances in regenerative medicine. The book provides relevant and up-to-date content on key topics, including the interdisciplinary integration of different aspects of stem cell biology and technology, diverse technologies, and their applications. By providing massive amounts of data on each individual, recent scientific advances are rapidly accelerating medicine. Cellular, molecular and genetic parameters from biological samples combined with clinical information can now provide valuable data to scientists, clinicians and ultimately patients, leading to the development of precision medicine. Equally noteworthy are the contributions of stem cell biology, bioengineering and tissue engineering that unravel the mechanisms of disease, regeneration and development.
  • Handbook of Data Science Approaches for Biomedical Engineering

    • 1st Edition
    • Valentina Emilia Balas + 3 more
    • English
    Handbook of Data Science Approaches for Biomedical Engineering covers the research issues and concepts of biomedical engineering progress and the ways they are aligning with the latest technologies in IoT and big data. In addition, the book includes various real-time/offline medical applications that directly or indirectly rely on medical and information technology. Case studies in the field of medical science, i.e., biomedical engineering, computer science, information security, and interdisciplinary tools, along with modern tools and the technologies used are also included to enhance understanding. Today, the role of Big Data and IoT proves that ninety percent of data currently available has been generated in the last couple of years, with rapid increases happening every day. The reason for this growth is increasing in communication through electronic devices, sensors, web logs, global positioning system (GPS) data, mobile data, IoT, etc.
  • Psychopharmacology of Neurologic Disease

    Handbook of Clinical Neurology Series
    • 1st Edition
    • Volume 165
    • English
    Psychopharmacology of Neurologic Disease, Volume 165 in the Handbook of Clinical Neurology series, provides clinicians with an up-to-date, critical review of the best approaches to treatment of neurologic disease as discussed by experienced clinical investigators. The book is organized into sections on dementia, delirium, movement disorders, hereditary degenerative disease, epilepsy and psychogenic seizures, brain vascular disease, pseudobulbar affect, traumatic brain injury, neuro-oncology, multiple sclerosis and other demyelinating disorders, chronic fatigue syndrome/fibromyalgi... pain, headache, sleep disorders, autoimmune encephalitis/anti- NMDA encephalitis, functional sensory neurologic symptom disorders and neurodevelopmental disorders. Each of these diagnostic categories has a significant incidence of behavioral symptomatology that is secondary to the neurologic diagnosis that can serve to complicate other therapeutic interventions, alter the course of illness, and cause distress in patients and family caregivers.
  • The Craft Brewing Handbook

    A Practical Guide to Running a Successful Craft Brewery
    • 1st Edition
    • Chris Smart
    • English
    The Craft Brewing Handbook: A Practical Guide to Running a Successful Craft Brewery covers the practical and technical aspects required to set up and grow a successful craft brewing business. With coverage of equipment options, raw material choice, the brewing process, recipe development and beer styles, packaging, quality assurance and quality control, sensory evaluation, common faults in beer, basic analyses, and strategies to minimize utilities, such as water and energy, this book is a one-stop shop for the aspiring brewer. The craft brewing sector has grown significantly around the world over the past decade. Many new breweries are technically naïve and have a thirst for knowledge. This book not only covers how to maximize the chances of getting production right the first time, it also deals with the inevitable problems that arise and what to do about them.
  • Chick Chorioallantoic Membrane Model and Precision Cancer Therapy

    • 1st Edition
    • Volume 46
    • Fuyuhiko Tamanoi
    • English
    Chick Chorioallantoic Membrane Model and Precision Cancer Therapy, Volume 46 in The Enzymes series, highlights new advances in the field, with this new volume presenting interesting chapters on the history of CAM model development, an overview of various CAM-based cancer models, the chick embryo chorioallantoic membrane as an in vivo experimental model to study multiple myelomak, bioluminescent CAM models for screening drugs against pancreatic cancer, X-ray sensitizer screen, patient derived tumor model for esophageal cancer, renal cancer and metastasis, nanoparticle characterization and tumor targeting, and patient derived tumor model for human nasopharyngeal carcinoma.
  • The Role of Ecosystem Services in Sustainable Food Systems

    • 1st Edition
    • Leonard Rusinamhodzi
    • English
    The Role of Ecosystem Services in Sustainable Food Systems reveals, in simple terms, the operational definition, concepts and applications of ecosystem services with a focus on sustainable food systems. The book presents case studies on both geographical and production system-wide considerations. Initial chapters discuss concepts, methodologies and the tools needed to understand ecosystem services in the broader food system. Middle and later chapters present different perspectives from case studies of ecosystem services derived from some of the key sustainable food production systems used by farmers, along with discussions on the challenges of deriving full benefits and how they can be overcome. Researchers, students, scientists, development practitioners and policymakers will welcome this reference as they continue their work related to sustainable food systems.
  • Inquiry, Treatment Principles, and Plans in Integrative Cardiovascular Chinese Medicine

    Volume 5
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Inquiry, Treatment Principles and Plans in Integrative Cardiovascular Chinese Medicine, volume five in the Integrative Cardiovascular Chinese Medicine series, provides the benefits of using the intake form, patient narratives and proper inquiry based on Chinese and Western medicine methods within the clinical setting to establish reliable treatment plans for cardiovascular patients. This reference is organized systematically into three sections covering questionnaires and testimony from patients, inquiry and physical examination techniques that are useful for examining cardiac patients, and specific cardiovascular symptoms in the new and returning patient, including definition of the symptom and clinical significance from Chinese and Western perspectives and treatment principles. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine with its clear, structured base to guide clinical practice and encourage collaboration between Chinese and Western medicine practitioners.
  • The Laboratory Rat

    • 3rd Edition
    • Mark A. Suckow + 3 more
    • English
    The third edition of The Laboratory Rat features updated information on a variety of topics, including rats as research models for basic and translational research in areas such as genomics, alcoholism, diabetes, metabolic syndrome, obesity, neuroscience, spinal cord injury, traumatic brain injury, regenerative medicine, and infectious disease. New information related to the husbandry and veterinary care of rats is provided including topics related to nutrition, reproduction, anesthesia and surgery, infectious and noninfectious disease, and the care of surgical and other fragile models. It is a premier source of information on the laboratory rat, this book will be of interest to veterinary and medical students, senior graduate students, postdocs and researchers who utilize animals in biomedical research.
  • Plant Systematics

    • 3rd Edition
    • Michael G. Simpson
    • English
    Plant Systematics, Third Edition, has made substantial contributions to plant systematics courses at the upper-undergraduate and first year graduate level, with the first edition winning The New York Botanical Garden's Henry Allan Gleason Award for outstanding recent publication in plant taxonomy, plant ecology or plant geography. This third edition continues to provide the basis for teaching an introduction to the morphology, evolution and classification of land plants. A foundation of the approach, methods, research goals, evidence and terminology of plant systematics are presented, along with the most recent knowledge of evolutionary relationships of plants and practical information vital to the field. In this new edition, the author includes greatly expanded treatments on families of flowering plants, as well as tropical trees (all with full-color plates), and an updated explanation of maximum likelihood and Bayesian inference algorithms. Chapters on morphology and plant nomenclature have also been enhanced with new material.
  • Insect Collection and Identification

    Techniques for the Field and Laboratory
    • 2nd Edition
    • Timothy J. Gibb + 1 more
    • English
    Insect Collection and Identification: Techniques for the Field and Laboratory, Second Edition, is the definitive text on all aspects required for collecting and properly preparing specimens for identification. This book provides detailed taxonomic keys to insects and related arthropods, giving recent classification changes to various insect taxa, along with updated preservation materials and techniques for molecular and genomic studies. It includes methods of rearing, storing and shipping specimens, along with a supporting glossary. New sections provide suggestions on how insects and other arthropods can be used within, and outside, the formal classroom and examine currently accepted procedures for collecting insects at crime scenes. This book is a necessary reference for entomology professionals and researchers who seek the most updated taxonomy and techniques for collection and preservation. It will serve as a valuable resource for entomology students and professionals who need illustrative and detailed information for easy arthropod identification.
  • Smell and Taste

    • 1st Edition
    • Volume 164
    • Richard L. Doty
    • English
    Smell and Taste, Volume 164 focuses on recent clinical research regarding two of our primary chemical senses, smell and taste. This volume is the most comprehensive neurology book on disorders of smell and taste function. Its major sections include epidemiology, anatomy and physiology, and clinical assessment, including neuroimaging, clinical conditions affecting smell and taste function (e.g., autoimmune disorders, head trauma, diseases of the nose and mouth, etc.). The widespread use of olfactory testing in clinical trials searching for biomarkers of neurodegenerative diseases is reviewed, along with evidence that smell dysfunction can be an early marker in neurodegenerative diseases and autoimmune disorders.
  • Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

    Volume 1
    • 1st Edition
    • Giuseppe Orlando + 4 more
    • English
    Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 1, sets a new standard in transplant and regenerative medicine. The book details the-state-of-the-art in modern whole pancreas and islet transplantation, including donor selection, immunosuppression, complications, allograft pathology, and more. As regenerative medicine is changing the premise of solid organ transplantation, this volume catalogs the technologies being developed and the methods being implemented to bioengineer or regenerate the endocrine pancreas in order to more effectively treat diabetes. Edited and authored by unparalleled leaders in the field, this new volume argues for a much needed synergy between organ transplantation and regenerative medicine.
  • Fresh-Cut Fruits and Vegetables

    Technologies and Mechanisms for Safety Control
    • 1st Edition
    • Mohammed Wasim Siddiqui
    • English
    Fresh-Cut Fruits and Vegetables: Technologies and Mechanisms for Safety Control covers conventional and emerging technologies in one single source to help industry professionals maintain and enhance nutritional and sensorial quality of fresh-cut fruits and vegetables from a quality and safety perspective. The book provides available literature on different approaches used in fresh-cut processing to ensure safety and quality. It discusses techniques with the aim of preserving quality and safety in sometimes unpredictable environments. Sanitizers, antioxidants, texturizers, natural additives, fortificants, probiotics, edible coatings, active and intelligent packaging are all presented. Both advantages and potential consequences are included to ensure microbial safety, shelf-life stability and preservation of organoleptic and nutritional quality. Industry researchers, professionals and students will all find this resource essential to understand the feasibility and operability of these techniques in modern-day processing to make informed choices.
  • Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas

    Volume 2
    • 1st Edition
    • Giuseppe Orlando + 4 more
    • English
    Transplantation, Bioengineering, and Regeneration of the Endocrine Pancreas, Volume 2, sets a new standard in transplant and regenerative medicine. The book details the state-of-the-art in modern islet auto-transplantation... also discussing current progress in regenerative medicine research in diabetes medicine. Regenerative medicine is changing the premise of solid organ transplantation, hence this volume catalogs technologies being developed and methods being implemented. Bioengineering and regenerating beta cells, clinical pancreas and islet transplantation, tissue engineering, biomaterial sciences, stem cell biology and developmental biology are all addressed and applied directly to diabetes medicine.
  • Neurofeedback

    The First Fifty Years
    • 1st Edition
    • James R. Evans + 2 more
    • English
    Neurofeedback: The First Fifty Years features broadly recognized pioneers in the field sharing their views and contributions on the history of neurofeedback. With some of the pioneers of neurofeedback already passed on or aging, this book brings together the monumental contributions of renowned researchers and practitioners in an unprecedented, comprehensive volume. With the rapid and exciting advances in this dynamic field, this information is critical for neuroscientists, neurologists, neurophysiologists, cognitive and developmental psychologists and other practitioners, providing a clear presentation of the frontiers of this exciting and medically important area of physiology.
  • Biology and Physiology of Freshwater Neotropical Fish

    • 1st Edition
    • Bernardo Baldisserotto + 2 more
    • English
    Biology and Physiology of Freshwater Neotropical Fish is the all-inclusive guide to fish species prevalent in the neotropical realm. It provides the most updated systematics, classification, anatomical, behavioral, genetic, and functioning systems information on freshwater neotropical fish species. This book begins by analyzing the differences in phylogeny, anatomy, and behaviour of neotropical fish. Systems such as cardiovascular, respiratory, renal, digestive, reproductive, muscular, and endocrine are described in detail. This book also looks at the effects of stress on fish immune systems, and how color and pigmentation play into physiology and species differentiation. Biology and Physiology of Freshwater Neotropical Fish is a must-have for fish biologists and zoologists. Students in zoology, ichthyology, and fish farming will also find this book useful for its coverage of some of the world’s rarest and least-known fish species.
  • Underexplored Medicinal Plants from Sub-Saharan Africa

    Plants with Therapeutic Potential for Human Health
    • 1st Edition
    • Namrita Lall
    • English
    Underexplored Medicinal Plants from Sub-Saharan Africa: Plants with Therapeutic Potential for Human Health examines a comprehensive selection of rarely explored plants that have been underestimated for their therapeutic value. The book contains monographs of medicinal plants, outlining their botanical description, geographical distribution, ethnobotanical usage, chemical constituents, sample and standard preparations and methods, and pharmacological properties. With expert contributors from South Africa, Mauritius, Seychelles, Cameroon and Nigeria, and the compilation of ethnobotanical, taxonomic and pharmacologic information for each species, this book is a valuable resource for researchers, academics in pharmacology, ethnopharmacology, medicinal plant sciences, and more.
  • Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy

    • 1st Edition
    • Volume 7
    • English
    Drug Efflux Pumps in Cancer Resistance Pathways: From Molecular Recognition and Characterization to Possible Inhibition Strategies in Chemotherapy, Volume Seven, describes the fundamental aspects of efflux pumps of the ATP-binding cassette superfamily in cancer resistance pathways, along with strategies to target and improve chemotherapy efficacy. Pumps of the ATP-binding cassette superfamily (ABCs) regulate the access of drugs to the intracellular space. In this context, the overexpression of ABCs is a well-known mechanism of multidrug resistance in cancer and is associated with therapeutic failure. Cancer types discussed include breast, endocrine, hematologic, gastrointestinal, musculoskeletal, lung, skin and central nervous system cancers. The book is a valuable source for researchers and advanced students in cancer, biology, pharmacology, pharmaceutical sciences, biomaterials and medical/clinical sciences that are interested in accessing a comprehensive compendium on efflux pumps in mechanisms of cancer resistance.
  • Evolution of the Human Brain: From Matter to Mind

    • 1st Edition
    • Volume 250
    • English
    Evolution of the Human Brain: From Matter to Mind, Volume 250 in the Progress in Brain Research, series documents the latest developments and insights about the origin and evolution of the human brain and mind. Specific sections in this new release include Evolution and development of the human cerebral cortex, Functional connectivity of the human cerebral cortex, Lateralization of the human cerebral cortex, Life history strategies and the human cerebral cortex, Evolution of the modern human brain, On the nature and evolution of the human mind, Origin and evolution of human cognition, Origin and evolution of human consciousness, and more.
  • Side Effects of Drugs Annual

    • 1st Edition
    • Volume 41
    • Sidhartha D. Ray
    • English
    Side Effects of Drugs Annual: A Worldwide Yearly Survey of New Data in Adverse Drug Reactions, Volume 41, first published in 1977, and continually published as a yearly update to the voluminous encyclopedia Meyler's Side Effects of Drugs, presents clinicians and medical investigators with a critical survey of new data and trends in adverse drug reactions and interactions. Topics covered in this new release include Central Nervous System Stimulants and Drugs that Suppress Appetite, Antidepressants, Lithium, Drugs of Abuse, Hypnotics and Sedatives, Antipsychotic Drugs, Antiepileptics, Opioid Analgesics and Narcotic Antagonists, Anti-Inflammatory and Antipyretic Analgesics and Drugs Used in Gout, and much more.
  • Oxidative Stress

    Eustress and Distress
    • 1st Edition
    • Helmut Sies
    • English
    Oxidative Stress: Eustress and Distress presents current knowledge on oxidative stress within the framework of redox biology and translational medicine. It describes eustress and distress in molecular terms and with novel imaging and chemogenetic approaches in four sections: A conceptual framework for studying oxidative stress. Processes and oxidative stress responses. Signaling in major enzyme systems (oxidative eustress), and damaging modification of biomolecules (oxidative distress). The exposome addresses lifelong exposure and impact on health, nutrient sensing, exercise and environmental pollution. Health and disease processes, including ischemia-reperfusion injury, developmental and psychological disorders, hepatic encephalopathy, skeletal muscle disorders, pulmonary disease, gut disease, organ fibrosis, and cancer. Oxidative Stress: Eustress and Distress is an informative resource useful for active researchers and students in biochemistry, molecular biology, medicinal chemistry, pharmaceutical science, nutrition, exercise physiology, analytical chemistry, cell biology, pharmacology, clinical medicine, and environmental science.
  • Biomimetic Nanoengineered Materials for Advanced Drug Delivery

    • 1st Edition
    • Afeesh Rajan Unnithan + 3 more
    • English
    Biomimetic Nanoengineered Materials for Advanced Drug Delivery is an indispensable guide for new developments in biomimetic nanoengineering for advanced drug delivery applications. Focusing on the fundamentals of a new type of nanocarriers for drug delivery in the most recent miRNA therapeutics, the book provides readers with detailed knowledge from the basics, to the most recent innovations. Early chapters of the book discuss a range of drug delivery techniques, including nanofibers, biomimetic polymers, 3D bioprinting, nanotechnology and radiofrequency sensitive nanocarriers. Later chapters explore miRNA therapeutics, magnetic nanoparticles, nanogel-based and ROS-mediated drug delivery systems. The book is a vital reference for biomaterials and nanomedicine researchers and clinicians with an interest in advanced drug delivery.
  • Molecular Biology of Neurodegenerative Diseases: Visions for the Future

    • 1st Edition
    • Volume 168
    • English
    Molecular Biology of Neurodegenerative Diseases: Visions for the Future, Volume 168 in the Progress in Molecular Biology and Translational Science series, provides the most topical, informative and exciting monographs available on a wide variety of research topics. The series includes in-depth knowledge on the molecular biological aspects of organismal physiology, with this release including chapters on Alzheimer's disease, Prion-like propagation of alpha-synuclein, What - if anything - can we learn about neurodegenerative diseases from yeast?, Mitochondrial rejuvenation and replacement as a novel strategy for treatment of age-related neurodegenerative diseases, Propagation and removal of cerebral amyloid angiopathy, and much more.
  • Data for Nurses

    Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems
    • 1st Edition
    • Molly McNett
    • English
    Data for Nurses: Understanding and Using Data to Optimize Care Delivery in Hospitals and Health Systems provides information for nurses on how to work with data to effectively evaluate and improve care delivery for patients. Quality, benchmarking, and research data are increasingly used to guide care in hospitals and health systems, and nurses are expected to actively use this information to identify interventions to optimize outcomes and meet reporting and financial targets. However, not all nurses receive formal training on data utilization, making interpretation and application of the different types of data difficult. This book provides information on topics such as benchmarking and reportable indicators, financial metrics, quality improvement, research, and implementation science, with applications to nursing practice. Important information on protective measures to guarantee integrity and security of personal patient data is also included. The book is a valuable resource for nurses and other healthcare professionals who require a basic understanding of key principles of data utilization in order to increase engagement in evidence-based practices, quality improvement, and mandatory reporting of key indices.
  • Advances in Immunology in China - Part A

    • 1st Edition
    • Volume 144
    • English
    Advances in Immunology in China - Part A, Volume 144, the latest release in the Advances in Immunology series, presents the latest release in a long-established and highly respected publication. The book includes current developments and comprehensive reviews in immunology. Articles address the wide range of topics that comprise immunology, with this release focusing on advances in immunology in China.
  • Plant Factory

    An Indoor Vertical Farming System for Efficient Quality Food Production
    • 2nd Edition
    • Toyoki Kozai + 2 more
    • English
    Plant Factory: An Indoor Vertical Farming System for Efficient Quality Food Production, Second Edition presents a comprehensive look at the implementation of plant factory (PF) practices to yield food crops for both improved food security and environmental sustainability. Edited and authored by leading experts in PF and controlled environment agriculture (CEA), the book is divided into five sections, including an Overview and the Concept of Closed Plant Production Systems (CPPS), the Basics of Physics and Physiology – Environments and Their Effects, System Design, Construction, Cultivation and Management and Plant Factories in Operation. In addition to new coverage on the rapid advancement of LED technology and its application in indoor vertical farming, other revisions to the new edition include updated information on the status of business R&D and selected commercial PFALs (plant factory with artificial lighting). Additional updates include those focused on micro and mini-PFALs for improving the quality of life in urban areas, the physics and physiology of light, the impact of PFAL on the medicinal components of plants, and the system design, construction, cultivation and management issues related to transplant production within closed systems, photoautotrophic micro-propagation and education, training and intensive business forums on PFs.
  • Perspectives of Ayurveda in Integrative Cardiovascular Chinese Medicine for Patient Compliance

    Volume 4
    • 1st Edition
    • Anika Niambi Al-Shura
    • English
    Perspectives of Ayurveda in Integrative Cardiovascular Chinese Medicine for Patient Compliance, volume four in the Integrative Cardiovascular Chinese Medicine series, provides a systematic perspective of therapeutic priority by examining the homeostasis of the body, mind and spirit through Ayurveda philosophies and universal attributes, including five key elements. Holism, patient compliance and ethics in medicine are discussed, as are responsibility, awareness and guidance for compliance in cardiac patients. Finally, strategies of compliant patients outline and compare Ayurvedic and Chinese medicine for dietary laws and recovery techniques, utilizing both systems for personal benefit and what compliance means and looks like in clinical settings. This important reference will aid cardiovascular researchers in the study of integrative Chinese and Western medicine, while also providing a clear, structured base to guide clinical practice and encourage collaboration between practitioners.
  • The Interaction of Food Industry and Environment

    • 1st Edition
    • Charis M. Galanakis
    • English
    The Interaction of Food Industry and Environment addresses all levels of interaction, paying particular attention to avenues for responsible operational excellence in food production and processing. Written at a scientific level, this book explores many topics relating to the food industry and environment, including environmental management systems, environmental performance evaluation, the correlation between food industry, sustainable diets and environment, environmental regulation on the profitability of sustainable water use in the food industry, lifecycle assessment, green supply chain network design and sustainability, the valorization of food processing waste via biorefineries, food-energy-environm... trilemma, wastewater treatment, and much more. Readers will also find valuable information on energy production from food processing waste, packaging and food sustainability, the concept of virtual water in the food industry, water reconditioning and reuse in the food industry, and control of odors in the food industry. This book is a welcomed resource for food scientists and technologists, environmentalists, food and environmental engineers and academics.
  • Principles of Tumors

    A Translational Approach to Foundations
    • 2nd Edition
    • Leon P. Bignold
    • English
    Principles of Tumors: A Translational Approach to Foundations, Second Edition, provides a concise summary of translational/interd... topics on the various aspects of tumors, especially abnormalities in their cells, their causes and effects on patients. Topics discussed include how genomic abnormalities in tumors may result from the actions of carcinogens and how genomic changes determine the cell biological/morpholog... abnormalities in tumor cell populations. In addition, the relationships between tumor cell genomics and therapeutic outcomes are described. There are also supporting appendices on general bioscience, including the principles of histology (the cells and tissues of the body), genetics, pathology, radiology and pharmacology. This book gives a thorough, detailed, yet concise account of the main bioscience, clinical and therapeutic aspects of tumors. It emphasizes the translational aspects of research into tumors with extensive discussions of interdisciplinary issues. The content in this book will be invaluable for researchers and clinicians involved in collaborative projects where it is necessary to understand fundamental issues in other branches of biomedicine.
  • Virus as Populations

    Composition, Complexity, Quasispecies, Dynamics, and Biological Implications
    • 2nd Edition
    • Esteban Domingo
    • English
    Virus as Composition, Complexity, Quasispecies, Dynamics, and Biological Implications, Second Edition, explains the fundamental concepts surrounding viruses as complex populations during replication in infected hosts. Fundamental phenomena in virus behavior, such as adaptation to changing environments, capacity to produce disease, and the probability to be transmitted or respond to treatment all depend on virus population numbers. Concepts such as quasispecies dynamics, mutations rates, viral fitness, the effect of bottleneck events, population numbers in virus transmission and disease emergence, and new antiviral strategies are included. The book's main concepts are framed by recent observations on general virus diversity derived from metagenomic studies and current views on the origin and role of viruses in the evolution of the biosphere.
  • Prognostic Epigenetics

    • 1st Edition
    • Volume 15
    • English
    This volume provides comprehensive information on how mapping an individual’s epigenome can be medically relevant and holds the potential to improve preventive medicine and precision therapeutics at an early-stage (prior to disease onset). In order to advance clinical adoption of the recently developed epigenetic approaches, it is necessary for translational scientists, clinicians, and students to gain a better understanding about epigenetic mechanisms that are associated with a particular disorder; and to be able to effectively identify biomarkers that can be applied in drug development and for better diagnosis and prognosis of diseases. Prognostic Epigenetics is the most-inclusive volume to-date specifically dedicated to epigenetic markers that have been developed for prognosis of diseases, recent advances in this field, the clinical implementation of this research, and the future outlook.
  • Encyclopedia of Gastroenterology

    • 2nd Edition
    • Ernst J. Kuipers
    • English
    Encyclopedia of Gastroenterology, Second Edition, Four Volume Set provides a comprehensive and concise reference on all aspects of gastroenterology and hepatology, including the organs in the gastrointestinal system, their functions in health and disease, and strategies or procedures to resolve or prevent problems and disease. This concise, up-to-date information includes comprehensive sections on the impact of nutrition, gastrointestinal microbiota, lifestyle, commonly used drugs, and surgical procedures on health and disease. Since the first edition, attention to the roles of nutrition and gastrointestinal microorganisms (microbiota, formerly Microbiota) in health and disease has skyrocketed. In addition, an entirely new section on obesity and diabetes is included.
  • Advances in Applied Microbiology

    • 1st Edition
    • Volume 109
    • Geoffrey M. Gadd + 1 more
    • English
    Advances in Applied Microbiology, Volume 109, continues the comprehensive reach of this widely read and authoritative review source in microbiology. Users will find invaluable references and information on a variety of areas relating to the topic.