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Books in Toxicology general

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Toxicology

  • 1st Edition
  • October 22, 2013
  • Y. Cohen
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 8 8 5 9 - 1
Advances in Pharmacology and Therapeutics, Volume 9: Toxicology is a collection of papers that tackles advances in toxicological research in context of pharmacology. The text first covers reactive metabolites and their implications for toxicology. Next, the selection deals with the experimental and clinical correlations of behavioral toxicology. The text also tackles toxicology and pharmacology of topical application. The book will be of great use to researchers and practitioners of health related disciplines.

Criteria (Dose/Effect Relationships) for Organochlorine Pesticides

  • 1st Edition
  • October 22, 2013
  • M. Mercier
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 3 7 5 0 - 6
Criteria (Dose/Effect Relationships) for Organochlorine Pesticides presents the effect of organochlorine compounds on the immunological processes. This book deals with several organochlorine pesticides. Organized into 15 chapters, this book begins with an overview of the properties and toxicology of dichlorodiphenyl trichloroethane (DDT), a potent non-systemic stomach and contact insecticide of high persistence on solid surface. This text then examines the absorption, metabolism, and excretion of lindane in laboratory animals and in humans as well. Other chapters consider the studies on the carcinogenic potential as well as the mutagenic effects of dieldrin. This book discusses as well the metabolism and pharmacokinetics of endrin, which is a non-systemic and persistent insecticide used primarily on field crops. The final chapter deals with the need for further evaluation of any possible long-term risks to humans from the production and use of the technical product. This book is a valuable resource for agriculturists and research workers.

Monographs on Fragrance Raw Materials

  • 1st Edition
  • October 22, 2013
  • D. L. J. Opdyke
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 9 7 - 0
Monographs on Fragrance Raw Materials contains a collection of monographs originally appearing in Food and Cosmetics Toxicology from the first issues in 1973 to the last ones in 1978. The monographs are organized in alphabetical order, as a regular feature of Food and Cosmetics Toxicology. This monograph will prove valuable to many readers of Food and Cosmetics Toxicology, as well as to the wider community of scientists and interested consumers.

Pharmacological Control of Heart and Circulation

  • 1st Edition
  • October 22, 2013
  • L. Tardos + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 7 8 - 9
Pharmacological Control of Heart and Circulation, Volume 1, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. Because the papers published in this volume cover diverse areas of the cardiovascular field, they had to be arranged into several smaller symposia. The common thread running through these symposia is their focus on some pathological condition of the heart and circulation as well as on their control by drugs. The first symposium is devoted to the pharmacological control of the adverse effects of coronary insufficiency including disturbances in rhythm. The second symposium is dedicated to cardiac hypertrophy; to the action of cardiac hypertrophy on the sensitivity of the heart to drugs; and to the changes in the biochemical parameters of the myocardium due to cardiomegaly. The third symposium deals with hypertension and its pharmacological control. Two separate symposia are devoted to new drugs, namely the fourth symposium to the cerebrovascular activity of Cavinton—a synthetic Vinca-derivative; and the fifth to a newly developed beta-adrenergic blocking agent, Tobanum, to its anti-arrhythmic action, its effect in myocardial ischemia and in hypertension. Finally, a short symposium on serotonin and serotonin antagonists, both of great importance in cardiovascular pharmacology, is included.

Modulation of Neurochemical Transmission

  • 1st Edition
  • October 22, 2013
  • E. S. Vizi
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 8 2 - 6
Modulation of Neurochemical Transmission, Volume II, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. It provides a summary of biochemical, electrophysiological, morphological, and pharmacological findings on the modulation of transmitter release. The 45 papers contained in this volume come from the most important laboratories and the contributors are among the world's foremost experts. Key topics discussed include the presynaptic inhibition of neurotransmitters; the properties of pre- and postsynaptic α receptors; histochemical mapping of dopamine neurons in the olfactory brain; neurophysiological aspects of dopaminergic supersensitivity; the role of ATPases in neurochemical transmission; and interaction between noradrenaline and vanadium on brain membrane ATPase. Also presented are papers on neurotransmission in the rat portal vein; the function of cysteine metabolism in rat brain; presynaptic dopamine receptors in sympathetic heart nerves of cats; LSD-induced behavioral effects in rats; and modulation of posttetanic response in the guinea-pig ileum.

Chemical Structure–Biological Activity Relationships: Quantitative Approaches

  • 1st Edition
  • October 22, 2013
  • F. Darvas
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 8 5 - 7
Chemical Structure-Biological Activity Relationships: Quantitative Approaches, Volume III, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. This volume focuses on the methodological aspects of QSAR. It also aims to inform the reader about the QSAR research conducted in East-European countries. This volume contains 38 presentations organized into six sections. Several lecturers deal with ""real prediction"" cases, i.e. activity estimation prior to the synthesis of the compounds. A particularly abundant section is devoted to the question of how the receptor models can be built up by means of QSAR calculations. Other sections present mathematical models and algorithms which could be applied to improve further the effectiveness of QSAR calculations. As another unique feature, a separate section treats the quantitative aspects of peptide structure-activity relationships—a field seemingly backward despite its evident importance. Hydrophobicity and its influence on biological potency along with the relationship of steric properties and biological activity are also discussed.

Monoamine Oxidases and Their Selective Inhibition

  • 1st Edition
  • October 22, 2013
  • K. Magyar
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 8 6 - 4
Monoamine Oxidases and Their Selective Inhibition, Volume IV, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. The discovery of the selective monoamine oxidase (MAO) inhibitors, such as clorgyline and deprenyl, has given a new impetus to MAO research as well as to the clinical applicability of these compounds. This volume contains 21 papers by researchers and clinicians from eight different countries. It begins with papers on the pharmacological effects and the biochemical mode of actions of deprenyl as well as some other new selective inhibitors. This is followed by communications concerning the biochemical methods applied in the study of the nature of MAO in the mitochondrial membrane. Finally, the neurologists provide an account of their experience with the clinical application of deprenyl, and other inhibitors in Parkinsonian patients. They also discuss the essential role of the dopaminergic mechanism with respect to the disease.

Opiate Receptors and the Neurochemical Correlates of Pain

  • 1st Edition
  • October 22, 2013
  • Susanna Fürst
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 7 8 8 - 8
Opiate Receptors and the Neurochemical Correlates of Pain, Volume V, documents the proceedings of the 3rd Congress of the Hungarian Pharmacological Society held in Budapest, 1979. The congress offered a good opportunity to stimulate discussions and exchange of ideas between scientists from various countries who approach the problem of narcotics and pain mechanisms in different ways. The 27 contributions in this volume have enriched knowledge in this rapidly expanding field of pharmacology. This volume begins with a discussion of opiate receptors. The results suggest the interaction of various morphine-like drugs with different opiate receptor populations. The existence in nerve tissue of specific opiate receptors binding morphine and other opioids has led to the assumption of endogenous ligand for opiate receptors. One section of the present volume is devoted to enkephalins and endorphins, their structure-activity relationships, interactions with transmitter and other systems, their behavioral effects, and to factors controlling their release. Some other aspects of nociception; the pathways involved in the mode of action of different types of analgesics, e.g. narcotics and non-narcotics; and their relations to inflammation and active substances, such as prostaglandins and substance P, are discussed from various aspects.

CNS Pharmacology Neuropeptides

  • 1st Edition
  • October 22, 2013
  • H. Yoshida + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 8 4 4 - 1
Advances in Pharmacology and Therapeutics II, Volume 1: CNS Pharmacology Neuropeptides contains the proceedings of the Eighth International Congress of Pharmacology held in Tokyo in 1981. This book is the first of a six-volume compilation of the scientific papers of invited speakers. Separating 26 papers as chapters, this book begins with an invited lecture on opioid peptides and their receptors. Other chapters describe opioid peptides and their relevance to central nervous system mechanisms; neuropeptides and related compounds affecting learning and memory; and pharmacological approaches to the study of sleep regulation. This book also explores the importance of kainic acid and related compounds as a pharmacological tool.

Neurotransmitters, Receptors

  • 1st Edition
  • October 22, 2013
  • H. Yoshida + 2 more
  • English
  • eBook
    9 7 8 - 1 - 4 8 3 1 - 4 8 4 7 - 2
Advances in Pharmacology and Therapeutics II, Volume 2: Neurotransmitters-Receptors is the second of a six-volume compilation of the scientific papers of invited speakers of the Eighth International Congress of Pharmacology. Organized into seven parts, this book begins with an invited lecture on the kinetic analysis of the neuronal and extraneuronal uptake and metabolism of catecholamines. Subsequent parts discuss the regulation of receptor-mediated events; presynaptic receptors in the peripheral and central nervous system; neurotransmitters; and receptor antibodies. The isolated nervous systems in the research of neurotransmission and trophic interactions between nerve and muscle are also discussed.

Related subjects

Toxicology