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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

    • HIV: Molecular Biology and Pathogenesis: Viral Mechanisms

      • 1st Edition
      • Volume 48
      • September 7, 2000
      • English
      • Paperback
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      • eBook
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      The cumulative death toll from AIDS has reached 16.3 million individuals, and more than 33 million persons are currently living with HIV-1. Although it is one of the most-widely studied viruses, many mysteries remain about this pathogen. In this comprehensive two-volume set, HIV-1: Molecular Biology and Pathogenesis, leading investigators in HIV research present a timely picture of the molecular mechanisms which guide HIV-1 expression and replication and provide the most current clinical strategies for combating this virus. Twenty-six teams of experts unravel structure-function interactions of HIV-1 with host cells and the resulting pathological consequences, review strategies fo treatment, and describe ongoing progress in developing animal models and prophylactic vaccines.The two volumes, covering viral mechanisms and clinical applications, respectively, are written by an international collection of AIDS expers from North America, Europe, Australia, and Asia.
    • The Quinolones

      • 3rd Edition
      • September 11, 2000
      • Vincent T. Andriole
      • English
      • Hardback
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      • Paperback
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      • eBook
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      Quinolones constitute a large class of synthetic antimicrobial agents that are highly effective in the treatment of many types of infectious diseases, particularly those caused by bacteria. New quinolones are continually being developed as bacterial species develop resistance to existing quinolones. This book presents the most current information available in our continual struggle to conquer disease. Over time, bacteria become resistant to medicines that are used to combat them. Because of this, the medical world is always in search of new and improved ways to battle these disease-causing bacteria. Quinolones are at the forefront of this research. Edited by one of the world's foremost authorities on the subject, the third edition of this highly successful title will serve as a valuable tool for primary care physicians and researchers interested in a comprehensive, up-to-date reference on the chemistry, mechanisms of action, development of resistance, and clinical efficacy of both currently available and newer quinolone compounds under investigation. This is the eagerly anticipated fully revised edition of the standard reference in the field.
    • Advances in Pharmacology

      • 1st Edition
      • Volume 46
      • May 5, 1999
      • English
      • Paperback
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      • Hardback
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      Each volume of Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental.
    • Adenosine Receptors and Parkinson's Disease

      • 1st Edition
      • October 15, 1999
      • Hiroshi Kase + 2 more
      • English
      • Paperback
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      • eBook
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      This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease. This book covers how the Parkinson's disease antagonist drug, A2A, has been researched, developed, and tested. It is an essential book for researchers interested in the basal ganglia, purine biology, and Parkinson's Disease.
    • Encyclopedia of Violence, Peace, and Conflict

      • 1st Edition
      • August 10, 1999
      • Lester R. Kurtz
      • English
      • Hardback
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      The Encyclopedia of Violence, Peace, and Conflict, a three-volume set written by more than 200 eminent contributors from around the world, takes advantage of increasing, worldwide awareness in the public, private, commercial, and academic sectors about manifestations of violence in all segments of society. While the contributors do not use these volumes to make specific arguments, they do describe and clarify the developments in thought that have led to current theories about and positions on violence and peace. Our reviewers consistently note that while many in-depth studies of war, peace, and aggression exist, the attendant specialization keeps scholars from learning about related fields. No publication competing with the Encyclopedia of Violence, Peace, and Conflict can satisfy their need for a vast introductory work to such a diverse and socially-important field. This major work includes more than 190 multidisciplinary articles with over 1,000 cross-references and more than 2,000 bibliography entries for further reading which are arranged alphabetically for easy access.
    • Membrane Permeability: 100 Years Since Ernest Overton

      • 1st Edition
      • Volume 48
      • May 17, 1999
      • English
      • Paperback
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      • Hardback
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      Membrane permeability is fundamental to all cell biology and subcellular biology. The cell exists as a closed unit. Import and export depend upon a number of sophisticated mechanisms, such as active transport, endocytosis, exocytosis, and passive diffusion. These systems are critical for the normal housekeeping physiological functions. However, access to the cell is also taken advantage of by toxic microbes (such as cholera or ptomaine) and when designing drugs. Ernest Overton, one of the pioneers in lipid membrane research, put forward the first comprehensive theory of lipid membrane structure. His most quoted paper on the osmotic properties of cells laid the foundation for the modern concepts of membrane function, most notably important in anesthesia. This book is designed to celebrate the centennial anniversary (in the first chapter) of Overton's work. Subsequent chapters present readers with up-to-date concepts of membrane structure and function and the challenge they pose for new explorations.
    • Cumulative Subject Index

      • 1st Edition
      • Volume 45
      • October 16, 1998
      • English
      • Hardback
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      • Paperback
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      Advances in Pharmacology provides a rich collection of reviews on timely topics. Emphasis is placed on the molecular bases of drug action, both applied and experimental. For easy reference, this volume provides a cumulative subject index covering Volumes 25-44.
    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 35
      • July 3, 1998
      • English
      • Hardback
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      • Paperback
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      Eminent scientists at the cutting edge of pharmacology and medicinal chemistry research provide us with yet another excellent addition to this famous series. The focus on bacterial resistance mechanisms serves to highlight an important area of unmet medical need requiring the attention of medicinal chemists. Five topical subjects are reviewed: the biosynthesis, metabolism and function of Vitamin D3 and the potential application of its analogues in bone disorders and immune-related diseases; the therapeutic potential of neurokinin antagonists; opioid receptor antagonists; the mechanisms of bacterial resistance; and a survey of recent advances in cannabinoid research. This volume will deservedly take its place in clinical and industrial pharmaceutical libraries, and will prove invaluable to medicinal chemists.
    • Asthma

      • 3rd Edition
      • April 20, 1998
      • Peter J. Barnes + 2 more
      • English
      • Hardback
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      • eBook
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      Now available in its Third Edition, Asthma: Basic Mechanisms and Clinical Management has become the reference text in asthma. This highly successful text sheds new light on the basic physiological and molecular mechanisms of asthma, how current treatments work, and how best to apply the latest knowledge to control this important disease. The Third Edition has undergone radical revision and includes several new chapters. It retains the virtues of the previous volumes by bringing together all of the recent research findings by internationally recognized experts on the causative mechanisms of asthma, including in-depth clinical aspects and therapy. The book presents an integrated approach toward the treatment of this disease with new concepts, changes in asthma management, and the development of new therapeutic agents. Asthma provides extensive references for researchers and clinicians who need to keep abreast of recent developments in this rapidly expanding field.