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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • The Practice of Medicinal Chemistry

      • 2nd Edition
      • June 11, 2003
      • Camille Georges Wermuth
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 7 7 7 8
      The Practice of Medicinal Chemistry, 2E, is a single-volume source on the practical aspects of medicinal chemistry. The successful first edition was nicknamed "The Bible" by medicinal chemists, and the second edition has been updated, expanded and refocused to reflect developments over the last decade. Emphasis is put on how medicinal chemists conduct their search for and design of new drug entities. In contrast to competing books, it focuses on the chemistry rather than pharmacological concepts or descriptions of the various therapeutic classes of drugs. Most medicinal chemists working in the pharmaceutical industry are organic synthetic chemists who must acquire a strong knowledge of medicinal chemistry as they enter the industry. This book aims to be their practical handbook - a complete guide to the drug discovery process.

    • Biophotonics, Part A

      • 1st Edition
      • Volume 360
      • February 12, 2003
      • English
      • eBook
        9 7 8 0 0 8 0 5 2 2 5 8 6
      The critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. Now with more than 300 volumes (all of them still in print), the series contains much material still relevant today—truly an essential publication for researchers in all fields of life sciences.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 40
      • September 25, 2002
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 8 3 5
      • Hardback
        9 7 8 0 4 4 4 5 1 0 5 4 9
      • eBook
        9 7 8 0 0 8 0 5 1 5 2 0 5
      This volume features accounts of the biological rationale, design and clinical potential of drug molecules; summaries of structure-activity relationships in topical areas of medicinal chemistry and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

    • Macrolide Antibiotics

      • 2nd Edition
      • June 10, 2002
      • Satoshi Omura
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 3 0 4 6
      • Hardback
        9 7 8 0 1 2 5 2 6 4 5 1 8
      • eBook
        9 7 8 0 0 8 0 5 3 5 6 8 5
      Macrolide Antibiotics: Chemistry, Biochemistry, and Practice, Second Edition explores the discovery of new macrolide antibiotics, their function, and their clinical use in diseases such as cancer, AIDS, cystic fibrosis and pneumonia. This book discusses the creation of synthetic macrolides and the mechanisms of antibiotic activity. The uses for antimicrobial macrolides in clinical practice are also covered. This book is designed to appeal to both the basic and applied research communities interested in microbiology, bacteriology, and antibiotic/antifunga... research and treament.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 39
      • April 24, 2002
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 8 4 2
      • Hardback
        9 7 8 0 4 4 4 5 0 9 5 9 8
      • eBook
        9 7 8 0 0 8 0 5 1 5 1 1 3
      This volume covers contemporary advances in five important areas of pharmacology and medicinal chemistry including: a comprehensive account of inhibitors of the caspase family of proteolytic enzymes that represent a new class of anti-inflammatory and antiapoptotic agents of potential value in rheumatoid arthritis, and other peripheral and central indications; adoc umented survey of semi-synthetic and totally synthetic antibiotics and anti HIV agents and their sites of interaction; inhibitors of the intracellular enzyme acyl-CoA: cholesterol O-acyltransferase (ACAT) developed for the treatment of hypercholesterolemia... and recent progress in growth hormone secretagogues, with the focus on strategies to improve oral bioavailability and duration of action. Inhibition of the proteolytic enzyme, hepatitis C protease N-3(NS3), required for viral replication, is one of the most attractive targets for HCV infections. Progress and prospects in the design of peptide and non-peptide inhibitors are described here. design and clinical potential of new drug molecules; valuable summaries of structure-activity relationships in topical areas of medicinal chemistry; and extensive references to the biology, medicinal chemistry and clinical aspects of each topic.

    • Signal Transduction

      • 1st Edition
      • March 8, 2002
      • Bastien D. Gomperts + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 2 8 9 6 3 2 3
      • eBook
        9 7 8 0 0 8 0 5 4 1 1 8 1
      • eBook
        9 7 8 0 0 8 0 5 7 4 9 7 4
      Signal Transduction is a well-illustrated, coherent look at cellular signaling processes. Beginning with the basics, it explains how cells respond to external cues, hormones, growth factors, cytokines, cell surfaces, etc., and then shows how these inputs are integrated and coordinated. The extensive color artwork provides the reader with a clearer comprehension of key topics, and margin notes are incorporated to highlight milestones in the evolution of signal transduction. This book serves as an invaluable resource for advanced undergraduates, graduate researchers, and established scientists working in cell biology, pharmacology, immunology, and related fields.

    • Vitamins and Hormones

      • 1st Edition
      • Volume 64
      • February 28, 2002
      • English
      • Paperback
        9 7 8 0 1 2 4 0 1 3 6 4 3
      • eBook
        9 7 8 0 0 8 0 5 2 2 8 6 9
      First published in 1943, Vitamins and Hormones is the longest-running serial published by Academic Press. In the early days of the Serial, the subjects of vitamins and hormones were quite distinct. The Editorial Board now reflects expertise in the field of hormone action, vitamin action, X-ray crystal structure, physiology, and enzyme mechanisms. Under the capable and qualified editorial leadership of Dr. Gerald Litwack, Vitamins and Hormones continues to publish cutting-edge reviews of interest to endocrinologists, biochemists, nutritionists, pharmacologists, cell biologists, and molecular biologists. Others interested in the structure and function of biologically active molecules like hormones and vitamins will, as always, turn to this series for comprehensive reviews by leading contributors to this and related disciplines.

    • Trends in Drug Research III

      • 1st Edition
      • Volume 32
      • January 25, 2002
      • H. van der Goot
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 0 4 1
      • eBook
        9 7 8 0 0 8 0 5 4 3 2 3 9
      The tradition of setting new trends in medicinal chemistry continued at the 13th Symposium where topics included chemical and biological diversity, new paradigms in drug action, and new insights in receptor mechanisms. Other topics of great interest discussed, and included in these proceedings, are the discoveries in green chemistry, the interface between organic synthesis and biosynthesis, the growing problem of resistant micro-organisms and the possibilities to identify new, and better, antibiotics. And finally, in recent developments, the discovery of small molecules with insulin sensitizing properties.

    • Handbook of Pesticide Toxicology

      • 2nd Edition
      • October 10, 2001
      • Robert Krieger
      • English
      • eBook
        9 7 8 0 0 8 0 5 3 3 7 9 7
      This revision of the highly acclaimed Hayes' Handbook of Pesticide Toxicology is an in-depth, scientific sourcebook concerning use, properties, effects, and regulation of pesticides. This edition is a comprehensive examination by international experts from academia, government research, and the private sector of critical issues related to the need, use, and nature of chemicals used in modern pest management. This two-volume set contains up-to-date information on a broad range of topics which establishes context of pesticide use and outlines how they are scientifically evaluated. Experts from a variety of disciplines contribute to this work. Some provide a fresh look at existing information, and others look ahead at issues that are central to understanding pesticide use and toxicology in modern integrated pest management.

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