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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

    • Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

      • 1st Edition
      • Volume 74
      • July 23, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 1 1 9 3
      • eBook
        9 7 8 0 1 2 8 0 3 1 2 0 9
      Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.
    • Modern Applications of Plant Biotechnology in Pharmaceutical Sciences

      • 1st Edition
      • July 22, 2015
      • Saurabh Bhatia + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 2 2 1 4
      • eBook
        9 7 8 0 1 2 8 0 2 4 9 8 0
      Modern Applications of Plant Biotechnology in Pharmaceutical Sciences explores advanced techniques in plant biotechnology, their applications to pharmaceutical sciences, and how these methods can lead to more effective, safe, and affordable drugs. The book covers modern approaches in a practical, step-by-step manner, and includes illustrations, examples, and case studies to enhance understanding. Key topics include plant-made pharmaceuticals, classical and non-classical techniques for secondary metabolite production in plant cell culture and their relevance to pharmaceutical science, edible vaccines, novel delivery systems for plant-based products, international industry regulatory guidelines, and more. Readers will find the book to be a comprehensive and valuable resource for the study of modern plant biotechnology approaches and their pharmaceutical applications.
    • Advances in Cancer Research

      • 1st Edition
      • Volume 127
      • June 18, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 9 2 0 6
      • eBook
        9 7 8 0 1 2 8 0 2 9 4 2 8
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. Here, once again, outstanding and original reviews are presented on a variety of topics, including taxane-anti-androgen... cross-resistance in advanced prostate cancer and proteasome inhibitors in the treatment of multiple myeloma.
    • Research Regulatory Compliance

      • 1st Edition
      • June 14, 2015
      • Mark A. Suckow + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 0 5 8 6
      • eBook
        9 7 8 0 1 2 4 2 0 0 6 5 4
      Research Regulatory Compliance offers the latest information on regulations and compliance in the laboratory. With the increasing complexity of regulations and need for institutional infrastructure to deal with compliance of animal use issues, as well as a requirement surrounding human subjects, this publication provides reputable guidance and information. The book is extremely helpful as a resource for researchers, administrators, and technicians in the laboratory, and is also a great asset for faculty or new researchers coming in to the laboratory environment. It will help prepare users for the deluge of regulatory and compliance issues they will face while conducting their scientific programs. The book is edited and authored by known leaders in the field of compliance and regulations, and contains extensive research on the topics. It represents the new standard for information in every laboratory.
    • Anti-Angiogenesis Drug Discovery and Development

      • 1st Edition
      • June 2, 2015
      • Atta-ur Rahman + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 9 6 3 2
      • eBook
        9 7 8 0 1 2 8 0 3 9 6 4 9
      The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians.
    • Recent Advances in Medicinal Chemistry, Volume 1

      • 1st Edition
      • June 2, 2015
      • Atta-ur Rahman + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 9 6 1 8
      • eBook
        9 7 8 0 1 2 8 0 3 9 6 2 5
      Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.
    • Medicinal Chemistry of Anticancer Drugs

      • 2nd Edition
      • April 28, 2015
      • Carmen Avendaño + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 6 2 6 4 9 3
      • eBook
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      Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.
    • Essential Pharmacokinetics

      • 1st Edition
      • March 25, 2015
      • Thorsteinn Loftsson
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 4 1 1 0
      • eBook
        9 7 8 0 1 2 8 0 1 4 9 1 2
      Essential Pharmacokinetics: A Primer for Pharmaceutical Scientists is an introduction to the concepts of pharmacokinetics intended for graduate students and new researchers working in the pharmaceutical sciences. This book describes the mathematics used in the mammillary model as well as the application of pharmacokinetics to pharmaceutical product development, and is useful as both a self-study and classroom resource. Content coverage includes detailed discussions of common models and important pharmacokinetic concepts such as biological half-life, clearance, excretion, multiple dosage regimens and more. Numerous equations, practical examples and figures are incorporated to clearly illustrate the theoretical background of pharmacokinetic behavior of drugs and excipients.
    • TRP Channels as Therapeutic Targets

      • 1st Edition
      • March 14, 2015
      • Arpad Szallasi
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 0 2 4 1
      • eBook
        9 7 8 0 1 2 4 2 0 0 7 9 1
      TRP Channels as Therapeutic Targets: From Basic Science to Clinical Use is authored by experts across academia and industry, providing readers with a complete picture of the therapeutic potential and challenges associated with using TRP channels as drug targets. This book offers a unique clinical approach by covering compounds that target TRP channels in pre-clinical and clinical phases, also offering a discussion of TRP channels as biomarkers. An entire section is devoted to the novel and innovative uses of these channels across a variety of diseases, offering strategies that can be used to overcome the adverse effects of first generation TRPV1 antagonists. Intended for all researchers and clinicians working toward the development of successful drugs targeting TRP channels, this book is an essential resource chocked full of the latest clinical data and findings.
    • Re-Engineering Clinical Trials

      • 1st Edition
      • December 16, 2014
      • Peter Schueler + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 2 4 6 7
      • eBook
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      The pharmaceutical industry is currently operating under a business model that is not sustainable for the future. Given the high costs associated with drug development, there is a vital need to reform this process in order to provide safe and effective drugs while still securing a profit. Re-Engineering Clinical Trials evaluates the trends and challenges associated with the current drug development process and presents solutions that integrate the use of modern communication technologies, innovations and novel enrichment designs. This book focuses on the need to simplify drug development and offers you well-established methodologies and best practices based on real-world experiences from expert authors across industry and academia. Written for all those involved in clinical research, development and clinical trial design, this book provides a unique and valuable resource for streamlining the process, containing costs and increasing drug safety and effectiveness.