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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Epi-Informatics

      • 1st Edition
      • February 24, 2016
      • Jose Medina-Franco
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 8 0 8 7
      • eBook
        9 7 8 0 1 2 8 0 2 8 0 9 4
      Epi-Informatics: Discovery and Development of Small Molecule Epigenetic Drugs and Probes features multidisciplinary strategies with strong computational approaches that have led to the successful discovery and/or optimization of compounds that act as modulators of epigenetic targets. This book is intended for all those using or wanting to learn more about computational methodologies in epigenetic drug discovery, including molecular modelers, informaticians, pharmaceutical scientists, and medicinal chemists. With a better understanding of different molecular modeling and cheminformatic approaches, readers can incorporate these techniques into their own drug discovery projects that may involve chemical synthesis and medium- or high-throughput screening. In addition, this book highlights the significance of epigenetic targets to the public health for molecular modelers and chemoinformatians. The goal of this reference is to stimulate ongoing multidisciplinary research and to further improve current computational methodologies and workflows in order to accelerate the discovery and development of epi-drugs and epi-probes.

    • Recent Advances in Medicinal Chemistry, Volume 1

      • 1st Edition
      • June 2, 2015
      • Atta-ur Rahman + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 9 6 1 8
      • eBook
        9 7 8 0 1 2 8 0 3 9 6 2 5
      Originally published by Bentham and now distributed by Elsevier, Recent Advances in Medicinal Chemistry, Volume 1 covers leading-edge research and recent developments in rational drug design, synthetic chemistry, bioorganic chemistry, high-throughput screening, combinatorial chemistry, drug targets, and natural product research and structure-activity relationship studies. The fourteen updated reviews include unique experimental data and references, and each article highlights an important topic in current medicinal chemistry research. Topics covered include: aureolic acid group of anti-cancer antibiotics and non-steroidal anti-inflammatory drugs; aromatase inhibitors in adjuvant endocrine treatment of early-stage breast cancer in postmenopausal women; Rho GTPases and statins in targeting and developing therapies for tumors; and more.

    • Research Regulatory Compliance

      • 1st Edition
      • June 14, 2015
      • Mark A. Suckow + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 4 2 0 0 5 8 6
      • eBook
        9 7 8 0 1 2 4 2 0 0 6 5 4
      Research Regulatory Compliance offers the latest information on regulations and compliance in the laboratory. With the increasing complexity of regulations and need for institutional infrastructure to deal with compliance of animal use issues, as well as a requirement surrounding human subjects, this publication provides reputable guidance and information. The book is extremely helpful as a resource for researchers, administrators, and technicians in the laboratory, and is also a great asset for faculty or new researchers coming in to the laboratory environment. It will help prepare users for the deluge of regulatory and compliance issues they will face while conducting their scientific programs. The book is edited and authored by known leaders in the field of compliance and regulations, and contains extensive research on the topics. It represents the new standard for information in every laboratory.

    • Anti-Angiogenesis Drug Discovery and Development

      • 1st Edition
      • June 2, 2015
      • Atta-ur Rahman + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 3 9 6 3 2
      • eBook
        9 7 8 0 1 2 8 0 3 9 6 4 9
      The inhibition of angiogenesis is an effective mechanism of slowing down tumor growth and malignancies. The process of induction or pro-angiogenesis is highly desirable for the treatment of cardiovascular diseases, wound healing disorders, and more. Efforts to understand the molecular basis, both for inhibition and induction, have yielded fascinating results. Originally published by Bentham and now distributed by Elsevier, Anti-Angiogenesis Drug Discovery and Development, Volume 2 is an compilation of well-written reviews on various aspects of the anti-angiogenesis process. These reviews have been contributed by leading practitioners in drug discovery science and highlight the major developments in this exciting field in the last two decades. These reader-friendly chapters cover topics of great scientific importance, many of which are considered significant medical breakthroughs, making this book excellent reading both for the novice as well as for expert medicinal chemists and clinicians.

    • Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B

      • 1st Edition
      • Volume 73
      • January 22, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 6 5 8 8
      • eBook
        9 7 8 0 1 2 8 0 2 6 9 1 5
      Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part B, a new volume of Advances in Pharmacology, presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years, which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

    • Stem Cell and Gene Therapy for Cardiovascular Disease

      • 1st Edition
      • August 21, 2015
      • Emerson c. Perin + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 1 8 8 8 0
      • eBook
        9 7 8 0 1 2 8 0 1 8 6 3 7
      Stem Cell and Gene Therapy for Cardiovascular Disease is a state-of-the-art reference that combines, in one place, the breadth and depth of information available on the topic. As stem cell and gene therapies are the most cutting-edge therapies currently available for patients with heart failure, each section of the book provides information on medical trials from contributors and specialists from around the world, including not only what has been completed, but also what is planned for future research and trials. Cardiology researchers, basic science clinicians, fellows, residents, students, and industry professionals will find this book an invaluable resource for further study on the topic.

    • Translational Research in Coronary Artery Disease

      • 1st Edition
      • October 29, 2015
      • Wilbert S. Aronow + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 3 8 5 3
      • eBook
        9 7 8 0 1 2 8 0 2 6 0 5 2
      Translational Research in Coronary Artery Disease: Pathophysiology to Treatment covers the entire spectrum of basic science, genetics, drug treatment, and interventions for coronary artery disease. With an emphasis on vascular biology, this reference fully explains the fundamental aspects of coronary artery disease pathophysiology. Included are important topics, including endothelial function, endothelial injury, and endothelial repair in various disease states, vascular smooth muscle function and its interaction with the endothelium, and the interrelationship between inflammatory biology and vascular function. By providing this synthesis of current research literature, this reference allows the cardiovascular scientist and practitioner to access everything they need from one source.

    • Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer

      • 1st Edition
      • Volume 74
      • July 23, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 3 1 1 9 3
      • eBook
        9 7 8 0 1 2 8 0 3 1 2 0 9
      Cytochrome P450 Function and Pharmacological Roles in Inflammation and Cancer, the latest volume in the Advances in Pharmacology series, presents not only the function of cytochrome P450 but also its pharmacological roles in inflammation and cancer.

    • Diversity and Functions of GABA Receptors: A Tribute to Hanns Möhler, Part A

      • 1st Edition
      • Volume 72
      • January 12, 2015
      • English
      • Hardback
        9 7 8 0 1 2 8 0 2 6 6 0 1
      • eBook
        9 7 8 0 1 2 8 0 2 6 9 2 2
      This new volume of Advances in Pharmacology presents the diversity and functions of GABA Receptors. The volume looks at research performed in the past 20 years which has revealed specific physiological and pharmacological functions of individual GABAA receptor subtypes, providing novel opportunities for drug development.

    • Medicinal Chemistry of Anticancer Drugs

      • 2nd Edition
      • April 28, 2015
      • Carmen Avendaño + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 6 2 6 4 9 3
      • eBook
        9 7 8 0 4 4 4 6 2 6 6 7 7
      Medicinal Chemistry of Anticancer Drugs, Second Edition, provides an updated treatment from the point of view of medicinal chemistry and drug design, focusing on the mechanism of action of antitumor drugs from the molecular level, and on the relationship between chemical structure and chemical and biochemical reactivity of antitumor agents. Antitumor chemotherapy is a very active field of research, and a huge amount of information on the topic is generated every year. Cytotoxic chemotherapy is gradually being supplemented by a new generation of drugs that recognize specific targets on the surface or inside cancer cells, and resistance to antitumor drugs continues to be investigated. While these therapies are in their infancy, they hold promise of more effective therapies with fewer side effects. Although many books are available that deal with clinical aspects of cancer chemotherapy, this book provides a sorely needed update from the point of view of medicinal chemistry and drug design.

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