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Books in Pharmacology

Elsevier's Pharmacology collection studies how drugs interact with biological systems to improve health and treat disease. It covers pharmacodynamics, exploring drug effects on biology, and pharmacokinetics, studying how the body affects drugs. Branches like Pharmacogenetics. Essential for pharmacologists, this collection offers invaluable insights into drug interactions, efficacy, and safety, crucial for advancing drug development and improving patient outcomes.

BooksJournals

    • Comprehensive Toxicology

      • 3rd Edition
      • December 1, 2017
      • Charlene McQueen
      • English
      • Hardback
        9 7 8 0 0 8 1 0 0 6 0 1 6
      • eBook
        9 7 8 0 0 8 1 0 0 6 1 2 2
      Comprehensive Toxicology, Third Edition, Fifteen Volume Set discusses chemical effects on biological systems, with a focus on understanding the mechanisms by which chemicals induce adverse health effects. Organized by organ system, this comprehensive reference work addresses the toxicological effects of chemicals on the immune system, the hematopoietic system, cardiovascular system, respiratory system, hepatic toxicology, renal toxicology, gastrointestinal toxicology, reproductive and endocrine toxicology, neuro and behavioral toxicology, developmental toxicology and carcinogenesis, also including critical sections that cover the general principles of toxicology, cellular and molecular toxicology, biotransformation and toxicology testing and evaluation. Each section is examined in state-of-the-art chapters written by domain experts, providing key information to support the investigations of researchers across the medical, veterinary, food, environment and chemical research industries, and national and international regulatory agencies. Thoroughly revised and expanded to 15 volumes that include the latest advances in research, and uniquely organized by organ system for ease of reference and diagnosis, this new edition is an essential reference for researchers of toxicology.

    • A Comprehensive and Practical Guide to Clinical Trials

      • 1st Edition
      • June 7, 2017
      • Delva Shamley + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 4 7 2 9 3
      • eBook
        9 7 8 0 1 2 8 0 4 7 3 0 9
      A Comprehensive and Practical Guide to Clinical Trials provides an overview of the entire process of clinical research in one thorough and easy-to-read handbook that offers those involved in clinical research a clear understanding of how the components of a study are related. It focuses on the practical aspects of the preparation and execution of a clinical trial and offers tools and resources to help the entire team understand how their responsibilities tie together with the tasks and duties of other members. This allows for better planning and prioritization, and can lead to more effective and successful clinical trials. With practical examples, checklists and forms, this book is a useful guide for planning and conducting clinical trials from beginning to end.

    • Adverse Events and Oncotargeted Kinase Inhibitors

      • 1st Edition
      • May 8, 2017
      • Giuseppe Tridente
      • English
      • Hardback
        9 7 8 0 1 2 8 0 9 4 0 0 6
      • eBook
        9 7 8 0 1 2 8 0 9 4 4 5 7
      Adverse Events and Oncotargeted Kinase Inhibitors gathers and evaluates data on adverse events associated with tyrosine kinase inhibitors (TKIs), a powerful anti-tumor drug class that has recently been introduced for human therapy. This book compiles a comprehensive safety profile of each TKI from experiences in official therapeutic indications, also exploring off-label exploratory investigations and postmarketing pharmaceutical surveillance databases. A brief history of each drug’s development and submission is provided, along with a more detailed analysis of the mechanism(s) of action involved in therapeutic activity or related to the insurgence of specific adverse events. Early chapters focus on general characteristics of TKIs, typology, and classification of adverse events, while the final chapters analyze TKIs as AE inducers and classes of AEs by system or organ involvement. This comprehensive resource compiles and critically reviews all of the relevant safety data for this class of drugs, with the goal of improving the understanding of pathogenesis and facilitating the prevention, monitoring, and management of these adverse events.

    • Pharmaceutical Medicine and Translational Clinical Research

      • 1st Edition
      • November 10, 2017
      • Divya Vohora + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 2 1 0 3 3
      • eBook
        9 7 8 0 1 2 8 0 2 0 9 8 2
      Pharmaceutical Medicine and Translational Clinical Research covers clinical testing of medicines and the translation of pharmaceutical drug research into new medicines, also focusing on the need to understand the safety profile of medicine and the benefit-risk balance. Pharmacoeconomics and the social impact of healthcare on patients and public health are also featured. It is written in a clear and straightforward manner to enable rapid review and assimilation of complex information and contains reader-friendly features.As a greater understanding of these aspects is critical for students in the areas of pharmaceutical medicine, clinical research, pharmacology and pharmacy, as well as professionals working in the pharmaceutical industry, this book is an ideal resource.

    • A Paradigm Shift to Prevent and Treat Alzheimer's Disease

      • 1st Edition
      • July 18, 2017
      • Howard Friel + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 2 5 9 4
      • eBook
        9 7 8 0 1 2 8 1 2 2 7 9 2
      A Paradigm Shift to Prevent and Treat Alzheimer’s Disease: From Monotargeting Pharmaceuticals to Pleiotropic Plant Polyphenols is the first book to systematically exhibit the powerful pleiotropic pharmacological effects on Alzheimer’s disease of plant-based compounds from ancient foods that humans have been consuming safely with substantial health benefits for thousands of years. These plant-based compounds include curcuminoids from turmeric, resveratrol from red wine and grape seed extract from other grape products, epigallocatechin-gal... (EGCG) from green tea, and oleocanthal and oleuropein from olive oil, in addition to a special extract, EGb 761, from the leaves of Ginkgo biloba, the oldest living species of tree on earth. This book also presents a new analytical framework that convincingly favors a multi-targeting ("pleiotropic") approach to the prevention and treatment of complex chronic diseases, in contrast to the mono-targeting of the pharmaceutical model. A Paradigm Shift to Prevent and Treat Alzheimer’s Disease is a unique and exciting resource for pharmaceutical scientists, pharmacologists, neurologists, general practitioners, research scientists in various medical and life sciences, healthcare professionals in clinical and executive positions, conventional medical schools, schools of naturopathic medicine, healthcare and medical journalists, executives in both national public healthcare systems and private insurers, and informed general readers.

    • Anxiety

      • 1st Edition
      • Volume 103
      • January 3, 2017
      • English
      • Hardback
        9 7 8 0 1 2 8 1 1 9 1 4 3
      • eBook
        9 7 8 0 1 2 8 1 1 9 1 5 0
      Anxiety, the latest volume in the Vitamins and Hormones series first published in 1943, and the longest-running serial published by Academic Press, provides up-to-date information on the roles that hormones and other factors play in anxiety and stress. Each volume focuses on a single molecule or disease that is related to vitamins or hormones, with the topic broadly interpreted to include related substances, such as transmitters, cytokines, growth factors, and others thoroughly reviewed.

    • Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids

      • 1st Edition
      • April 4, 2017
      • Surendra Nimesh + 2 more
      • English
      • Hardback
        9 7 8 0 0 8 1 0 0 5 5 7 6
      • eBook
        9 7 8 0 0 8 1 0 0 5 6 3 7
      Advances in Nanomedicine for the Delivery of Therapeutic Nucleic Acids addresses several issues related to safe and effective delivery of nucleic acids (NAs) using nanoparticles. A further emphasis would be laid on the mechanism of delivery of NAs, the barriers encountered and the strategies adapted to combat them. An exhaustive account of the advantages as well shortcomings of all the delivery vectors being employed in delivery of various NAs will be provided. On final note the regulatory aspects of nanoparticles mediated NA would be discussed, with focus on their clinical relevance. The design and development of nucleic acid-based therapeutics for the treatment of diseases arising from genetic abnormalities has made significant progress over the past few years. NAs have been widely explored for the treatment of cancer and infectious diseases or to block cell proliferation and thereby caused diseases. Advances in synthetic oligonucleotide chemistry resulted in synthesis of NAs that are relatively stable in in vivo environments. However, cellular targeting and intracellular delivery of NAs still remains a challenge. Further development of NA-based therapeutics depends on the progress of safe and effective carriers for systemic administration. Nanomedicine has facilitated availability of vectors with diminished cytotoxicity and enhanced efficacy which are rapidly emerging as systems of choice. These vectors protect NAs from enzymatic degradation by forming condensed complexes along with targeted tissue and cellular delivery. During the past few years, a myriad reports have appeared reporting delivery of NAs mediated by nanoparticles. This book will provide an overview of nanoparticles being employed in the in vitro and in vivo delivery of therapeutically relevant NAs like DNA, siRNA, LNA, PNA, etc.

    • From Artemisia annua L. to Artemisinins

      • 1st Edition
      • July 8, 2017
      • Youyou Tu
      • English
      • Hardback
        9 7 8 0 1 2 8 1 1 6 5 5 5
      • eBook
        9 7 8 0 1 2 8 1 1 6 5 6 2
      From Artemisia annua L. to Artemisinins: The Discovery and Development of Artemisinins and Antimalarial Agents is the first book that systematically introduces the origin and development of artemisinine and artemisinine-based drugs. It includes four distinct sections, including Artemisia annua L., Artemisinin, Dihydroartemisinin, and other artemisinin derivatives. Tu Youyou, the chief inventor of artemisinin, together with other members from the research team, have written a book that will be a valuable reference work for both researchers involved in the medical industry and scholars who are interested in undertaking innovative research.

    • Progress in Medicinal Chemistry

      • 1st Edition
      • Volume 56
      • March 15, 2017
      • English
      • Hardback
        9 7 8 0 4 4 4 6 3 9 3 9 4
      • eBook
        9 7 8 0 4 4 4 6 3 9 4 3 1
      Progress in Medicinal Chemistry, Volume 56 provides a review of eclectic developments in medicinal chemistry. This volume includes chapters covering recent advances in cancer therapeutics, fluorine in medicinal chemistry, a perspective on the next generation of antibacterial agents derived by manipulation of natural products, a potential new era for Chagas Disease drug discovery, and imaging in drug development. Specific chapters cover timely topics, such as the development of LRRK2 inhibitors for the treatment of Parkinson's, and recent discoveries and developments in TRPA1 modulators. Users will find a comprehensive resource on the topic of medicinal chemistry that also discusses avenues for the acceleration of drug discovery programs.

    • Medicinal Plants for Holistic Health and Well-Being

      • 1st Edition
      • September 27, 2017
      • Namrita Lall
      • English
      • Paperback
        9 7 8 0 1 2 8 1 2 4 7 5 8
      • eBook
        9 7 8 0 1 2 8 1 2 4 7 6 5
      Medicinal Plants for Holistic Health and Well-Being discusses, in depth, the use of South African plants to treat a variety of ailments, including tuberculosis, cancer, periodontal diseases, acne, postmacular hypomelanosis, and more. Plants were selected on the basis of their traditional use, and the book details the scientific evidence that supports their pharmacological and therapeutic potential to safely and effectively treat each disease. Thus, this book is a valuable resource for all researchers, students and professors involved in advancing global medicinal plant research. Many plants found in South Africa are also found in other parts of the world. Each chapter highlights plants from other worldwide locations so that scientists can study which plants belong to the same family, and how similar qualities can be used to treat a specific disease.

Related subjects

Biochemical pharmacology

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