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Books in Neurology

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511-520 of 554 results in All results

Gene Therapy of the Central Nervous System: From Bench to Bedside

  • 1st Edition
  • November 11, 2005
  • Michael G. Kaplitt + 1 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 5 4 3 7 - 5
Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped create this field and are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects of interest to anyone exploring or using gene therapy for neurobiological applications in research and clinical praxis.

Neuroimaging Part B

  • 1st Edition
  • Volume 67
  • October 12, 2005
  • Michael F. Glabus
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 3 6 6 8 6 8 - 4
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 7 8 6 0 - 9
Comprised of two separate volumes, Neuroimaging provides a state-of-the-art review of a broad range of neuroimaging techniques applied to both clinical and research settings. The breadth of the methods covered is matched by the depth of description of the theoretical background. Part B covers the application of neuroimaging in both research and clinical settings for the study of anxiety disorders, dementia, depression, schizophrenia, functional somatic syndromes, stroke, and multiple sclerosis using a range of neuroimaging modalities including CT, PET, SPECT, DTI, structural MRI and fMRI. One chapter is devoted to the study of brain development using structural MRI, and one chapter to the study of pediatric neurobehavioral disorders using fMRI. One of the most exciting recent applications of neuroimaging to the area of genetics is covered, and with the theory and application of neuroreceptor imaging in psychiatry, forms the final two chapters. The two parts of Neuroimaging complement each other providing in-depth information on a broad range of routine and cutting edge techniques that is not available in any other text. This book is superbly written and beautifully illustrated by contributors working at the top of their chosen specialty.

Autonomic Dysfunction After Spinal Cord Injury

  • 1st Edition
  • Volume 152
  • October 11, 2005
  • Lynne C. Weaver + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 4 4 4 - 5 1 9 2 5 - 2
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 6 0 1 0 - 9
Autonomic dysfunction is a major and poorly understood consequence of spinal cord injury. It is a cause of very serious disability and requires much more research. It should be a focus of treatment strategies. This book will be of interest to anyone involved in research and treatment of spinal cord injury since it helps to explain the tremendously negative impact on the body caused by cord injury that is not as obvious as paralysis and loss of sensation. It contains a compilation of what is known about bladder, cardiovascular, bowel and sexual dysfunction after spinal cord injury, as it relates to the changes within the autonomic nervous system control of these functions.The book begins with a description of the time course of autonomic dysfunctions and their ramifications from the first hours after a spinal cord injury to the more stable chronic states. The next section contains three chapters that address anatomical findings that may provide some of the foundation for autonomic dysfunctions in many of the systems. The system-specific chapters then follow in four sections. Each section begins with a chapter or two defining the clinical problems experienced by people with cord injury. The following chapters present research, basic and clinical, that address the autonomic dysfunctions.

Atlas of Ambulatory EEG

  • 1st Edition
  • September 21, 2005
  • Bernard S. Chang + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 5 4 1 0 - 8
Atlas of Ambulatory EEG covers the areas of clinical neurophysiology, an atlas that comprehensively depicts normal, abnormal, and artifactual findings from actual ambulatory EEG recordings in a convenient and easily accessible format. As the use of ambulatory EEG has increased in recent years, the need for a concise atlas of ambulatory EEG has grown significantly, since ambulatory EEG tracings are subject to their own unique issues and artifacts, often not discussed in standard EEG atlases. This book begins with several chapters that introduce the history, technology, and clinical utility of ambulatory EEG. The bulk of the atlas consists of a page-by-page display of high-quality ambulatory EEG excerpts that are easy to review and come with short annotations describing the relevant findings. Atlas of Ambulatory EEG is a critical resource for anyone involved in the interpretation of ambulatory EEG studies.

Models of Seizures and Epilepsy

  • 1st Edition
  • August 30, 2005
  • Asla Pitkänen + 2 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 0 8 8 5 5 4 - 1
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 5 7 0 2 - 4
An understanding of mechanisms underlying seizure disorders depends critically on the insights provided by model systems. In particular with the development of cellular, molecular, and genetic investigative tools, there has been an explosion of basic epilepsy research. Models of Seizures and Epilepsy brings together, for the first time in 30 years, an overview of the most widely-used models of seizures and epilepsy. Chapters cover a broad range of experimental approaches (from in vitro to whole animal preparations), a variety of epileptiform phenomenology (including burst discharges and seizures), and suggestions for model characterization and validation, such as electrographic, morphologic, pharmacologic, and behavioral features. Experts in the field provide not only technical reviews of these models but also conceptual critiques - commenting on the strengths and limitations of these models, their relationship to clinical phenomenology, and their value in developing a better understanding and treatments. Models of Seizures and Epilepsy is a valuable, practical reference for investigators who are searching for the most appropriate laboratory models for addressing key questions in the field. It also provides an important background for physicians, fellows, and students, offering insight into the potential for advances in epilepsy research.

MRI Atlas of Human White Matter

  • 1st Edition
  • May 11, 2005
  • Susumu Mori + 3 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 5 6 1 6 - 4
Recent advances in modern imaging techniques that can be used non-invasively for the visualization of the human brain have greatly enhanced the knowledge of brain anatomy and the understanding of its relationship to brain function. A unique new MRI modality, called diffusion tensor imaging (DTI) allows the three-dimensional study of the large white matter (WM) fiber bundles at macroscopic resolution (millimeter scale). MRI Atlas of Human White Matter provides a three-dimensional and two-dimensional in vivo atlas of various white matter tracts in the human brain. The images are based on diffusion tensor imaging and various tracts are reconstructed three-dimensionally from the data. Following an introduction and description of the methodology (Chapters 1 and 2), the 3D anatomy of individual tracts is delineated in Chapter 3. Chapter 4 consists of a series of color-coded orientation maps to delineate white matter anatomy in a slice-by-slice manner, in which the structures are extensively annotated. This richly illustrated Atlas is a valuable resource for students studying white matter anatomy and researchers working in brain research and radiology. This book also provides the structural assignment, which will assist neuroradiologists when interpreting diffusion tensor images in routine clinical studies.

Multiple Sclerosis As A Neuronal Disease

  • 1st Edition
  • April 22, 2005
  • Stephen Waxman
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 7 3 8 7 6 1 - 1
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 8 9 4 1 - 4
This book examines the role of neurons in multiple sclerosis (MS) and the changes that occur in neurons as a result of MS. It places MS in a new and important perspective that not only explains the basis for symptom production, remission, and progress in MS, but also promises to open up new therapeutic possibilities.

Movement Disorders

  • 1st Edition
  • January 25, 2005
  • Mark S. LeDoux
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 7 0 5 6 - 6
The use of animal models is a key aspect of scientific research in numerous fields of medicine. This book vigorously examines the important contributions and application of animal models to the understanding of human movement disorders and will serve as an essential resource for basic neuroscientists engaged in movement disorders research. Academic clinicians, translational researchers and basic scientists are brought together to connect experimental findings made in different animal models to the clinical features, pathophysiology and treatment of human movement disorders. A vital feature of this book is an accompanying DVD with video clips of human movement disorders and their corresponding animal models. The book is divided into sections on Parkinson disease, Huntington disease, dystonia, tremor, paroxysmal movement disorders, ataxia, myoclonus, restless legs syndrome, drug-induced movement disorders, multiple system atrophy, progressive supranuclear palsy/corticobasal degeneration and spasticity. This book serves as an essential resource for both clinicians interested in the science being generated with animal models and basic scientists studying the pathogenesis of particular movement disorders.

International Review of Neurobiology

  • 1st Edition
  • Volume 62
  • December 18, 2004
  • Ronald J. Bradley + 2 more
  • English
  • eBook
    9 7 8 - 0 - 0 8 - 0 4 9 5 5 2 - 1
Published since 1959, International Review of Neurobiology is a well-known series appealing to neuroscientists, clinicians, psychologists, physiologists, and pharmacologists. Led by an internationally renowned editorial board, this important serial publishes both eclectic volumes made up of timely reviews and thematic volumes that focus on recent progress in a specific area of neurobiology research.

Magnetic Resonance in Epilepsy

  • 2nd Edition
  • December 16, 2004
  • Ruben Kuzniecky + 1 more
  • English
  • Hardback
    9 7 8 - 0 - 1 2 - 4 3 1 1 5 2 - 7
  • eBook
    9 7 8 - 0 - 0 8 - 0 5 3 5 7 1 - 5
Remarkable advances in imaging have increased the importance of MRI for diagnostic, treatment and management of epilepsy. Neuroimaging of patients with epilepsy no longer simply deals with the technology and interpretation of images but also with issues of brain metabolism, energetics, cognition and brain dysfunction. The first edition of Magnetic Resonance in Epilepsy came into clinical practice in 1995 with a revolutionary idea; that is, MR is as important as EEG in the clinical management of patients with epilepsy. The second edition of Magnetic Resonance in Epilepsy, the only comprehensive text in the field of epilepsy neuroimaging, reviews fundamental concepts and new advances in MR technology, computerized analysis, MR spectroscopy, DWI and other neuroimaging techniques such as PET, SPECT and MEG application to the study of patients with epileptic disorders.

Related subjects

Autonomic nervous system

Clinical neuropathology

Clinical neurophysiology

Epilepsy

Neuro ophthalmology

Neuroimaging

Neurological research

Pediatric neurology