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Elsevier

Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B

    • 1st Edition
    • Lung-Yi Loey Mak + 1 more
    • English
    Therapeutic Potentials of Tenofovir Alafenamide in Hepatitis B offers a comprehensive examination of the therapeutic potentials of Tenofovir Alafenamide (TAF) in hepatitis B, providing a succinct and up-to-date summary of all relevant evidence for this first-line oral antiviral agent. The text delves into key topics such as the pharmacological profile of TAF, its comparative efficacy against traditional antiviral agents, safety and tolerability, and the impact of TAF on drug resistance. Additionally, it explores the use of TAF in special populations, including pediatrics, the elderly, and individuals with renal impairment, as well as future directions in hepatitis B treatment strategies.Readers will discover the diverse potential applications of TAF in chronic hepatitis B, informed by valuable lessons learned from HIV treatment while also gaining insights into future therapeutic possibilities. Authored by leading experts in the field, each chapter presents focused and insightful perspectives, making this book an indispensable resource for practitioners and researchers alike. Serving as a critical resource for physicians, researchers, pharmacologists, and biomedical scientists, this book highlights the core knowledge necessary for understanding TAF and its clinical applications.

  • Artificial Intelligence in Brain Disorders

    Innovations in Diagnosis and Treatment
    • 1st Edition
    • Pranav Kumar Prabhakar + 3 more
    • English
    Artificial Intelligence in Brain Disorders: Innovations in Diagnosis and Treatment focuses on the utilization of AI and machine learning to enhance current practices in the diagnosis and treatment of neurological disorders. Each chapter provides in-depth exploration of specific areas where AI can improve existing methodologies, offering practical guidance, case studies, and research findings that can be directly applied in the field. It explains the application of AI in diagnosing and treating major neurological illnesses and showcases the potential of AI in predicting diseases such as epilepsy and neurodegenerative disorders.As such, this book offers a detailed overview of AI and machine learning techniques relevant to neurological research.

  • Nano Drug Delivery Systems for Colon Cancer

    Innovations, Challenges, and Applications
    • 1st Edition
    • Arun Kumar Singh + 4 more
    • English
    Nano Drug Delivery for Colon Cancer: Innovations, Challenges, and Applications is a breakthrough exploration that delves into the latest advancements in colon cancer diagnosis and treatment. This comprehensive guide, composed of 11 detailed chapters, focuses on the design, synthesis, and application of various nanodrug delivery systems, showcasing how nanoparticulate drug carriers can significantly enhance therapeutic efficacy through strategic design. Aimed at graduates, clinical researchers, and scientists, this book addresses the complexities and challenges in drug and gene delivery. Beyond its technical insights, the book highlights the global health impact of colon cancer and offers a roadmap for developing more efficient and targeted treatments.It serves as a vital resource, fostering interdisciplinary knowledge and advancements that have the potential to revolutionize colon cancer therapeutics. The book's interdisciplinary approach ensures it is a beacon of knowledge for those seeking to navigate and innovate within this critical field.

  • Probiotics

    A Comprehensive Exploration of Health Benefits and Innovation
    • 1st Edition
    • Ranbir Chander Sobti
    • English
    Probiotics: A Comprehensive Exploration of Health Benefits and Innovation explores the potential of probiotics and their fundamental role in human health and disease prevention. The book offers a thorough understanding of how beneficial microorganisms can enhance overall well-being and potentially transform treatment approaches across multiple disciplines. The first section lays the groundwork by exploring the fundamentals of probiotics, prebiotics, and their interactions with the human microbiome, while the second section examines the role of probiotics in disease prevention and management, highlighting their impact on conditions such as diabetes, obesity, and mental health.The third section discusses specialized applications of probiotics in women's health, pediatrics, and geriatrics, as well as their innovative uses in skin care and nutrition. Finally, the fourth section investigates the future potential of probiotics in synthetic biology, in personalized health, and in combatting antibiotic resistance. With contributions from a diverse group of experts in the field, the book serves as an interdisciplinary resource for researchers, clinicians, and industry professionals eager to explore the therapeutic potential and benefits of probiotics.

  • Artificial Intelligence in Livestock Omics

    Applications, Challenges, and Future Perspectives
    • 1st Edition
    • Navid Ghavi Hossein-Zadeh
    • English
    Artificial Intelligence in Livestock Omics: Applications, Challenges, and Future Perspectives delves into the cutting-edge intersection of AI and livestock science, exploring how advanced algorithms are transforming the analysis and application of omics data in livestock production. This book addresses the convergence of AI and biotechnology, highlighting how these fields are not only transforming livestock farming but also contributing to broader goals within personalized medicine, genetic improvement, and the development of resilient animal breeds. Sections provide readers with practical insights, real-world case studies, and a forward-looking perspective on the future of AI-driven livestock management.The integration of AI with omics technologies can also aid in global efforts to improve food security, animal welfare, and sustainable agricultural practices. Whether a researcher, industry professional, or policymaker, this book offers valuable tools and strategies to enhance precision farming, improve animal health, and drive sustainable agriculture in the digital age.

  • Molecular Insights into Proteinopathies

    Increased Scope from Neurodegeneration to other Pathologies of the Brain
    • 1st Edition
    • Eva Žerovnik + 1 more
    • English
    Molecular Insights into Proteinopathies: Increased Scope from Neurodegeneration to other Pathologies of the Brain investigates the molecular events that lead to various diseases. The book is divided into four parts, the first of which delves into protein aggregation across a range of diseases, including Alzheimer’s disease, Parkinson’s disease, schizophrenia, and neuropsychiatric diseases. It then moves on to discuss signaling pathways and biomarkers of disease, including oxidative stress, mitochondrial decline, and dysregulated molecular pathways. The third part explores small molecules as modulators of key processes in the pathogenesis of proteinopathies, including antioxidants, polyphenol compounds, metal chelators, and repurposed drugs that modulate proteinopathies.The final section considers biophysical methods, molecular dynamics, and machine learning approaches in the study of these aspects. The book provides a detailed overview of protein dysfunction and its implications for health and disease, aiding understanding of protein condensates and aggregates, protein misfolding, co-chaperoning and toxicity of pre-amyloid aggregates. By understanding the fundamental properties underlying these, the book paves the way for investigating how proteinopathies could be treated.

  • Enzyme Microfluidics

    • 1st Edition
    • Volume 737
    • English
    Microfluidic Enzymology, Volume 737 in the Methods in Enzymology series, presents detailed methodological descriptions and protocols covering a wide range of microfluidics-based approaches for mechanistic enzymology, high-throughput screening, and enzyme engineering campaigns. The volume includes both established methods as well as recent advances in the field. Chapters include protocols for fabricating and running microfluidic devices, state-of-the-art high-throughput droplet and spatial array-based methods, new methods for activity detection, and recent developments integrating microfluidic methods with structural biology and machine learning approaches.

  • Childhood Disorders of Rickets and Osteomalacia

    A Comprehensive Review
    • 1st Edition
    • Suma Uday
    • English
    Childhood Disorders of Rickets: A Comprehensive Review defines the pathophysiology of rickets and the various genetic and acquired conditions that present with rickets in childhood. This comprehensive review details the various forms of rickets, the histopathology, recent advances leading to new therapeutic options in treating rickets, and the role of Vitamin D and calcium in nutritional rickets. Additionally, the authors explore future research in various areas of nutritional and non-nutritional forms of rickets.Written by global experts for clinicians and researchers treating and studying the various forms of rickets, the book will also be of interest to those working in public health and policy makers working on the prevention of nutritional rickets worldwide.

  • Innovations and Human Factors Challenges in Healthcare Product Design

    • 1st Edition
    • Kamalpreet Sandhu + 3 more
    • English
    Innovations and Human Factors Challenges in Healthcare Product Design covers best practices and advanced design methods to capture, document, and validate various challenges at the early stage of the design process, also delving into how to mitigate design strategies to address those challenges without compromising the cost, effort, safety, and quality of the device. The book provides a comprehensive collection of technical notes, research designs, design methods and processes, case studies, comprehensive literature on the industrial impact of design methods and processes, and applications of digital technologies for design, analysis, manufacturing, testing, and deployment. Readers will find multidisciplinary coverage of the application of technology and science for product design in healthcare sectors.

  • Foundation of Microfluidics Device Technology

    • 1st Edition
    • Volume 225
    • English
    Microfluidics is a rapidly expanding field that is recognized as a powerful platform for accelerating biological science research and innovation. It has the potential to reduce the cost and reagent consumption by enabling the precise manipulation of a small amount of fluids through microchannel ranging from ten to hundreds micrometres in size. It is a multidisciplinary domain, which integrates molecular analysis, molecular biology, and microelectronics. It has demonstrated practical applications in the design and fabrication of systems capable of processing low volumes of fluids while enabling multiplexing, automation, and high-throughput screening. Since its emergence in early 1980s, microfluidics has significantly contributed in the development of inkjet printheads, DNA chips, lab-on-a-chip technology, micro-propulsion, and micro-thermal technologies. Microfluidic chips comprise intricate networks of microchannels and chambers designed to manipulate fluids at the microscale.This volume presents the fundamental of microfluidics and microfluidics devices including computational design and fabrication, artificial intelligence and internet of things for microfluidics devices, materials, surface modifications and functionalization of microfluidics, fabrication of paper based microfluidics. Additional topics include microfluidics for generation of biomaterials, microfluidics for multi-omics analysis, lab-on-the-chip, microfluidics for 2D and 3D cell culture systms, microfluidics for drug and gene delivery, biomimetic models, and the economic considerations associated with microfluidics devices development. This volume is designed to serve as valuable resource for students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand microfluidics and apply microfluidics technology/devices in various fields. It provides a strong foundation to help the extension of microfluidics knowledge and accelerate research, innovation, technology and practical applications.

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