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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Hyaluronan

      • 1st Edition
      • October 4, 2002
      • J F Kennedy + 3 more
      • English
      • eBook
        9 7 8 1 8 4 5 6 9 3 1 2 1
      Hyaluronan and its derivatives has developed very quickly in the last few years from a scientific novelty into an important new material for a diverse range of medical and biomaterial applications. This landmark conference focused on developments and applications in the use of hyaluronan in tissue repair and reconstruction, drug delivery systems, anti-cancer treatments and joint recovery and engineering.The entire range of hyaluronan progress is covered in depth by the more than 135 individual papers:Analytical chemistryStructural elucidation and basic chemistryElectron microscopy and atomic force microscopyProduction... purification and characterisationQual... in production systemsChemical modificationDerivati... and propertiesCross-link... radical modificationPhysical characterisationRheo... phenomenaInteraction with water and solution propertiesCell biologyControl and regulation of HA synthasesCell surface chemistryHA cell receptors and cell signallingInteractio... with proteins and other biological ligandsBiophysical aspectsEffects on pain receptorsNeurobiolog... in organisation of extracellular matrixRole in development (embryogenesis): cell movement/migrationMe... applicationsUses in cartilage and wound repairInflammationWo... regenerative healingSurgery and tissue engineeringViscosupp... / osteoarthritisViscoa... and viscoprotectionAnti-... applicationsBrug delivery systemsBinding onto tumour cells and metastases

    • Genetics of Movement Disorders

      • 1st Edition
      • October 3, 2002
      • Stefan M. Pulst
      • English
      • Paperback
        9 7 8 0 1 2 3 8 8 7 3 1 3
      • eBook
        9 7 8 0 0 8 0 5 3 2 4 1 7
      Hereditary or genetic diseases featuring involuntary movements constitute a major aspect of the practice of neurology, functional neurosurgery, genetics, and many areas of basic and applied neuroscience research. Describing the current knowledge on these disorders, Genetics of Movement Disorders brings together information essential for clinicians, geneticists, and neuroscientists in one source. Utilizing a convenient and accessible format, the book is designed to allow easy identification of relevant information, with the overall organization of topics following established phenotypic classifications of movement disorders such as Parkinsonian syndromes, chorea, ataxia, and major categories of diseases grouped by gene locus. This book broadly appeals to neurologists, neuroscientists, geneticists, as well as cell and molecular biologists and hematologists.

    • Gene Expression at the Beginning of Animal Development

      • 1st Edition
      • Volume 12
      • September 30, 2002
      • M.L. DePamphilis
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 0 4 8 8
      • eBook
        9 7 8 0 0 8 0 9 3 0 0 5 3
      The beginning of life may be a miracle to some, and a mystery to others, but it is certainly one of the most exciting and perhaps controversial fields of scientific investigation in the 21st century. Among the metazoa, life begins when an egg is fertilized by a sperm. The sperm provides a genetic blueprint from the father and perhaps some critical proteins. The egg provides a genetic blueprint from the mother together with a large reservoir of mRNAs and proteins that are required for DNA replication, cell division and the onset of zygotic gene expression. All of the thousands of genes in these two mature gametes are transcriptionally silent and remain so until fertilization.This work focuses on three biological systems, providing the reader with a clear understanding of the current state of affairs, and the ability to identify common principles as well as critical differences that are responsible for beginning the process of animal development. The essays presented will be of practical value to all those who are interested in improving fertilization in vitro, in designing novel methods of contraception, in developing preimplantation genetic diagnosis for various diseases, in cloning animals by transplanting nuclei from adult cells to an enucleated egg, and in the application of embryonic stem cells to curing genetic diseases or replacing damaged tissues. But above all, this volume is offered to those who simply have an insatiable curiosity about life and its beginnings.

    • Advances in Cancer Research

      • 1st Edition
      • Volume 85
      • September 30, 2002
      • George F. Vande Woude + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 0 0 6 6 8 5 8
      • eBook
        9 7 8 0 0 8 0 4 8 8 2 1 9

    • Advances in Cancer Research

      • 1st Edition
      • Volume 86
      • September 30, 2002
      • George F. Vande Woude + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 1 3 1 4 5
      • Hardback
        9 7 8 0 1 2 0 0 6 6 8 6 5
      • eBook
        9 7 8 0 0 8 0 4 8 8 2 2 6

    • Advances in Enzyme Regulation

      • 1st Edition
      • Volume 42
      • September 19, 2002
      • George Weber
      • English
      • Hardback
        9 7 8 0 0 8 0 4 4 1 2 3 8
      • eBook
        9 7 8 0 0 8 0 9 1 3 5 0 6
      Volume 42 lives up to its goal of advancing a few steps ahead of the general front of mammalian enzymic and metabolic regulation studies. This volume contains papers of 25 outstanding scientists working at the cutting edge of metabolic regulation. Much of the volume focuses on novel aspects of signal transduction with an emphasis on nuclear expression.One of the highlights of this volume is the Special Symposium Lecture. This was given for 15 years by Sir Hans A. Krebs who passed away 20 years ago. It was now given by Professor Sir Hans L. Kornberg, University Professor at Boston University.These volumes continue to be a source of information and inspiration and a laboratory and advanced teaching companion. The immediate and long-range significance of these cutting-edge presentations of these novel topics should be immediately clear to the reader.

    • Advances in DNA Sequence-Specific Agents

      • 1st Edition
      • Volume 4
      • September 17, 2002
      • B.J. Chapman
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 0 9 6 9
      • Paperback
        9 7 8 0 4 4 4 5 4 5 3 6 7
      • eBook
        9 7 8 0 0 8 0 5 2 6 1 3 3
      This series encompasses design, synthesis, application, and analytical methods (including clinical and in vitro) for the study of these critical interactions. As our understanding of the genome and proteome expands, general developments in the field of DNA sequence specific interaction are likely to play an increasingly important role. Accordingly, manuscripts have been solicited from experts covering a diverse range of fields, reflecting the cross-disciplinary and dynamic nature of the series.Volume 4 describes work on the modification of DNA by AT specific anticancer drugs, DNA alkylation events which involve metabolite generation, DNA sequence recognition by two selective binders, bulged DNA microenvironments as molecular targets, DNA sequence specific binding by short peptides and the analysis of DNA-protein interactions using DNase I footprinting methodology.Features include:• Expert contributors from the Biomedical world• Emerging areas of drug design and therapeutic applications• Nucleic acid-protein interactions• Color graphics of molecular modeling analyses• New and emerging methodologies

    • Sensing, Signaling and Cell Adaptation

      • 1st Edition
      • Volume 3
      • September 16, 2002
      • J.M. Storey + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 0 1 4 0
      • Hardback
        9 7 8 0 4 4 4 5 1 1 4 7 8
      • eBook
        9 7 8 0 0 8 0 5 4 1 0 7 5
      In this volume of Cell and Molecular Responses to Stress articles provide up-to-date information on key areas of signal sensing (sensing of pain, heat, cold, light, infrared radiation), molecules involved in the intracellular transmission of these signals, metabolic responses to stress including changes in gene expression and production of specialized proteins that aid cell responses to factors including interrupted blood supply (ischemia), oxygen limitation (hypoxia/anoxia), freezing and dehydration, amino acid limitation, radiation and processing drugs. There are chapters which also provide insights into new technologies (such as cDNA arrays), analysis of metabolic control theory (a key method for analysing stress effects on cells), and examine how enzymes evolve in the face of stress.

    • Recent Advances in Nucleosides: Chemistry and Chemotherapy

      • 1st Edition
      • September 11, 2002
      • C.K. Chu
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 9 5 1 2
      • eBook
        9 7 8 0 0 8 0 5 4 0 3 6 8
      The book covers up-to-date information on nucleosides and antiviral chemotherapy contributed by the world experts in the field of nucleoside. This book is the result of a meeting honoring Dr. Jack J. Fox, who was one of the pioneers in nucleoside chemistry and chemotherapy. This book consists of 15 excellent chapters in the area, which include topics from recent synthetic methodologies, nucleoside kinase implicated in chemotherapy and drug design, excellent reviews on antiviral agents, nucleoside metabolism/mode of action in parasites, new compounds under clinical and pre-clinical trials, IMPDH inhibitors to review on nucleoside prodrugs.

    • Handbook of the Speed of Sound in Real Gases

      • 1st Edition
      • September 4, 2002
      • Allan J. Zuckerwar
      • English
      • Hardback
        9 7 8 0 1 2 7 8 2 5 1 0 6
      • eBook
        9 7 8 0 0 8 0 5 4 5 2 8 8
      After the introductory chapters in each volume, the material in each chapter starts out with definitions and engineering formulas, applies these to the individual gases, and proceeds to advanced theory at the molecular level. The formulas and theory are illustrated with examples throughout. Uncertainty, in both measurement and prediction, is a recurring theme throughout both volumes.The engineering formulas are suited to engineering and science students at the undergraduate level. The advanced theory is for professionals and students at the graduate level. The Handbook will survey the state of the art from 1921 to the present, pointing out gaps in our present knowledge.

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