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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Protein Phosphatases

      • 1st Edition
      • Volume 366
      • December 12, 2003
      • Susanne Klumpp + 1 more
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 2 6 9 9
      • eBook
        9 7 8 0 0 8 0 9 1 7 3 9 9
      Protein phosphatases are a group of enzymes responsible for the dephosphorylation of various proteins and enzymes in a cell. This role is an extremely important one since protein phosphorylation and dephosphorylation is required for the regulation of a large number of cellular activities.

    • Frontiers in Viral Hepatitis

      • 1st Edition
      • December 12, 2003
      • R.F. Schinazi + 2 more
      • English
      • Hardback
        9 7 8 0 4 4 4 5 0 9 8 6 4
      • eBook
        9 7 8 0 0 8 0 5 3 2 0 4 2
      Frontiers in Viral Hepatitis provides a compilation of the research from over 40 key opinion leaders in the field of Hepatitis. The book focuses on the latest advances in the search for new, more effective therapeutic options and related topics in viral hepatitis. These include regulatory issues, epidemiology, and emerging viruses; immunology and vaccines; viral hepatitis B and C infections in children; genetics pathology and viral diagnosis; cell systems and animal models; novel therapeutics for hepatitis B and C; resistance and therapeutic strategies in humans; and prevention and treatment options for hepatocellular carcinoma.The breadth of information published in this volume provides insight into current prevention and treatment options. Recent advances in our understanding of the molecular biology, immunology and pathogenesis of hepatitis viruses have accelerated at a remarkable rate, offering a more comprehensive perspective on hepatitis.

    • International Review of Cytology

      • 1st Edition
      • Volume 230
      • December 10, 2003
      • Kwang W. Jeon
      • English
      • Hardback
        9 7 8 0 1 2 3 6 4 6 3 4 7
      • eBook
        9 7 8 0 0 8 0 4 9 5 5 9 0
      The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Contributors to this volume include Giacomo Azzali, Annalena Civinini, Isabelle Creveaux, Bernard Dastugue, Arnold De Loof, Robert Didier, Steven K. Fisher, Nicolas Goncalves-Mendex, Geoffrey P. Lewis, Annie Meiniel, Robert Meiniel, Tom Meeusen, Inge Mertens, Valentina Patrizia Gallo, and Liliane Schoofs.

    • The Flaviviruses: Structure, Replication and Evolution

      • 1st Edition
      • Volume 59
      • December 10, 2003
      • English
      • Hardback
        9 7 8 0 1 2 0 3 9 8 5 9 1
      • Paperback
        9 7 8 0 1 2 3 9 1 7 8 2 9
      • eBook
        9 7 8 0 0 8 0 4 9 3 8 1 7
      Over 50% of known flaviviruses have been associated with human disease. The Flavivirus genus constitutes some of the most serious human pathogens including Japanese encephalitis, dengue and yellow fever. Flaviviruses are known for their complex life cycles and epidemic spread, and are considered a globally-emergent viral threat. Structure, Replication and Evolution is the first volume of The Flaviviruses and presents the latest research covering the conceptual advances on aspects such as the characterization of virus structure, cellular receptors, mechanisms of virus entry, host and viral components of the RNA replicase.

    • Differentiation of Embryonic Stem Cells

      • 1st Edition
      • Volume 365
      • December 5, 2003
      • English
      • eBook
        9 7 8 0 0 8 0 5 4 6 1 6 2
      This volume covers all aspects of embryonic stem cell differentiation, including mouse embryonic stem cells, mouse embryonic germ cells, monkey and human embryonic stem cells, and gene discovery.

    • Macromolecular Crystallography, Part C

      • 1st Edition
      • Volume 368
      • December 5, 2003
      • Charles W. Carter Jr.
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 6 6 8 5
      • eBook
        9 7 8 0 0 8 0 4 9 7 0 9 9
      Accurate molecular structures are vital for rational drug design and for structure-based functional studies directed toward the development of effective therapeutic agents and drugs. Crystallography can reliably predict structure, both in terms of folding and atomic details of bonding.

    • Murine Homeobox Gene Control of Embryonic Patterning and Organogenesis

      • 1st Edition
      • Volume 13
      • December 3, 2003
      • Thomas Lufkin
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 4 9 8 1
      • eBook
        9 7 8 0 0 8 0 4 9 7 3 5 8
      The first homeobox gene was molecular cloned nearly two decades ago, and since that time tremendous progress has been made in our understanding of the distribution of homeobox genes in the genomes of many animal species and the common functional role the encoded homeodomains play in cell-type specification, morphogenesis and development.The amino acid sequence of the homeodomain, as well as the presence of other conserved protein domains, has allowed the classification of homeodomain-containi... proteins (homeoproteins) into over thirty separate families (e.g. Hox, Dlx, Msx, Otx, Hmx, Cdx etc.). In many cases a single gene has been shown to fully direct the morphogenesis and development of a complex tissue, organ or even an entire body segment. Yet how this "master" regulatory ability of homeoproteins functions at the molecular level to a large degree still remains a mystery, in part owing to our limited understanding of the nature of both homeoprotein transcriptional cofactors and even more elusively, the downstream targets of homeoprotein function. In the reviews presented here it is limited primarily to what has been learned in vertebrate systems, principally focusing on the mouse, owing to the strengths of the technical approaches currently existing in murine developmental genetics that are not yet available to the same degree in other vertebrate species. Despite this mammalian predilection, a common thread to each of these reviews is the underlying importance of what has been learned about homeoprotein function in other animal species, particularly arthropods like Drosophila.

    • Energy Metabolism and Lifespan Determination

      • 1st Edition
      • Volume 14
      • December 1, 2003
      • M.P. Mattson
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 4 9 2 9
      • Paperback
        9 7 8 0 4 4 4 5 6 0 1 1 7
      • eBook
        9 7 8 0 0 8 0 4 9 4 7 6 0
      Experts in the fields of energy metabolism, aging and oxidative stress provide an integrated view of how mechanisms involved in regulating energy metabolism are linked to fundamental processes of aging including cellular stress resistance and free radical production. During evolution signal transduction pathways and organ systems have been optimised for the efficient seeking, ingestion, storing and using of energy. These signalling pathways play prominent roles in lifespan determination with insulin and related signalling pathways being prime examples. The authors consider how lifespan and healthspan can be extended through knowledge of energy metabolism with the experimental model of dietary restriction being one example. The information in this volume of ACAG will foster novel approaches and experiments for further understanding the roles of energy metabolism in aging and disease.

    • Development of Auditory and Vestibular Systems-3: Molecular Development of the Inner Ear

      • 1st Edition
      • Volume 57
      • November 26, 2003
      • Raymond Romand + 1 more
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 0 9 1 5
      Thanks to advances in genetics and genomics, research on inner ear development has flourished. Better approaches and experimental models have shed light on the function of a variety of vertebrate genes and their related proteins. This latest volume of Current Topics in Developmental Biology delves into this new research to show how the discovery of more genes involved in the development of the inner ear leads to the generation of new models that examine a wealth of issues -- from the origins of human deafness to the roles of genes during inner ear induction, development and differentiation. The wide variety of experimental approaches will help readers to understand the broad range of issues related to inner ear morphogenesis and other concepts from complementary areas of investigation. This state-of-the-art overview will be essential reading for researchers, clinicians and students alike.

    • International Review of Cytology

      • 1st Edition
      • Volume 229
      • November 26, 2003
      • Kwang W. Jeon
      • English
      • Paperback
        9 7 8 0 1 2 4 0 1 3 7 8 0
      • eBook
        9 7 8 0 0 8 0 4 9 5 5 8 3
      The acclaimed International Review of Cytology series presents current advances and reviews in cell biology, both plant and animal. Articles address structure and control of gene expression, nucleocytoplasmic interactions, control of cell development and differentiation, and cell transformation and growth. Authored by some of the foremost scientists in the field, each volume provides up-to-date information and directions for future research. Contributors to this volume are Yasushi Matsui, Janice A. Fischer, Robert J. Reid, Julie Hayes, Jüri J. Rumessen, Takayuki Hoson, Kouichi Soga, Shiro Suetsugu, and Tadaomi Takenawa.

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