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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Tribology and Biophysics of Artificial Joints

      • 1st Edition
      • Volume 50
      • December 2, 2005
      • Pinchuk
      • English
      • Hardback
        9 7 8 0 4 4 4 5 2 1 6 2 0
      • eBook
        9 7 8 0 0 8 0 4 5 8 0 8 3
      Joint endoprosthetics - the science of implanting artificial joints into the human body - has been around since the 1960’s, and consistent advancements are leading to better practice, materials and mechanics. The present book is devoted to the biophysics and effect of wear, friction and lubrication on artificial joints. The important aspects of biocompatibility and wear resistance are reviewed and a retrospective analysis of modern joint endoprosthetic designs is presented. Data on clinical aspects of endoprosthetics are cited in support of the text. Advancements in genetic engineering, and promising new techniques of designing bone and cartilage transplants are explored, and a critical comparison between tribological mechanisms of operation and natural joint functioning are made. An exceptional resource for all specialists in orthopedy, biophysics, immunology and engineers engaged in developing artificial joints.
    • Knobil and Neill's Physiology of Reproduction

      • 3rd Edition
      • December 1, 2005
      • Jimmy D. Neill
      • English
      • eBook
        9 7 8 0 0 8 0 5 3 5 2 7 2
      The 3rd edition, the first new one in ten years, includes coverage of molecular levels of detail arising from the last decade's explosion of information at this level of organismic organization. There are 5 new Associate Editors and about 2/3 of the chapters have new authors. Chapters prepared by return authors are extensively revised. Several new chapters have been added on the topic of pregnancy, reflecting the vigorous investigation of this topic during the last decade.The information covered includes both human and experimental animals; basic principels are sought, and information at the organismic and molecular levels are presented.
    • Medical Textiles and Biomaterials for Healthcare

      • 1st Edition
      • November 30, 2005
      • Subhash C. Anand + 3 more
      • English
      • Hardback
        9 7 8 1 8 5 5 7 3 6 8 3 2
      • eBook
        9 7 8 1 8 4 5 6 9 4 1 0 4
      Medical textiles are a major growth area within the technical textiles industry and the range of applications continues to grow and increase in diversity with every new development. Recent innovations include novel chitosan-alginate fibres for advanced wound dressings, ultrasonic energy for bleaching cotton medical textiles, durable and rechargeable biocidal textiles, spider silk supportive matrix for cartilage regeneration, barbed bi-directional surgical sutures and intelligent textiles for medical applications.Medical textiles and biomaterials for healthcare is a culmination of the worldwide research into medical textiles and biomaterials. It is divided into eight parts covering the main areas of basic biomaterials, healthcare and hygiene products, infection control and barrier materials, bandaging and pressure garments, woundcare materials, implantable and medical devices and smart technologies. Each part contains a comprehensive overview written by leading experts in the area. The overviews are then followed by a selection of the best papers from the 2003 MEDTEX Conference, hosted by the University of Bolton. It has been extensively edited to produce what is expected to be the leading reference on this subject.
    • The Chemistry of Evolution

      • 1st Edition
      • November 29, 2005
      • R.J.P Williams + 1 more
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 6 0 0 5
      • Hardback
        9 7 8 0 4 4 4 5 2 1 1 5 6
      • eBook
        9 7 8 0 0 8 0 4 6 0 5 2 9
      Conventionally, evolution has always been described in terms of species. The Chemistry of Evolution takes a novel, not to say revolutionary, approach and examines the evolution of chemicals and the use and degradation of energy, coupled to the environment, as the drive behind it. The authors address the major changes of life from bacteria to man in a systematic and unavoidable sequence, reclassifying organisms as chemotypes. Written by the authors of the bestseller The Biological Chemistry of the Elements - The Inorganic Chemistry of Life (Oxford University Press, 1991), the clarity and precision of The Chemistry of Evolution plainly demonstrate that life is totally interactive with the environment. This exciting theory makes this work an essential addition to the academic and public library.
    • Phase II Conjugation Enzymes and Transport Systems

      • 1st Edition
      • Volume 400
      • November 28, 2005
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 8 0 5 9
      • eBook
        9 7 8 0 0 8 0 8 8 4 2 9 5
      This volume on conjugation enzymes and transporters serves to bring together current methods and concepts in an interesting, important and rapidly developing field of cell and systems biology. Phase II Conjugation Enzymes and Transport Systems focuses on the so-called Phase II enzymes of drug metabolism (xenobiotics), which has important ramifications for endogenous metabolism and nutrition. Also included are aspects on Phase III, transport systems. This volume of Methods in Enzymology presents current knowledge and methodology on glucuronidation, sulfation, acetylation, and transport systems in this field of research. Together with the volumes on Quinones and Quinone Enzymes (volumes 378 and 382), and on Glutathione Transferases and gamma-Glutamyl Transpeptidases (volume 401), the state of knowledge on proteomics and metabolomics of many pathways of (waste) product elimination, enzyme protein induction and gene regulation and feedback control is provided. This volume will help stimulate future investigations and speed the advance of knowledge in systems biology.
    • Microarrays

      • 1st Edition
      • November 22, 2005
      • Hans-Joachim Müller + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 0 8 8 5 4 3 5
      • eBook
        9 7 8 0 0 8 0 9 1 6 6 6 8
      Microarrays is an invaluable laboratory manual for anyone conducting experiments in the field of molecular biology or medical biochemistry who needs to understand and use microarray technologies. These technologies are especially appropriate in genome analysis, diagnostics, and studies involving differential gene expression. Providing straightforward explanations, the authors demonstrate proven methods for biochip application and an overview of presently available instruments, biochips, and software. Chapters cover the different requirements for DNA and protein chips, as well as spotters and scanners. The book also covers high throughput screening, patent research, and the minimum requirements for setting up or expanding a microarray laboratory.
    • Essentials of Stem Cell Biology

      • 1st Edition
      • November 21, 2005
      • Robert Lanza + 6 more
      • English
      • eBook
        9 7 8 0 0 8 0 4 5 6 5 5 3
      This abridged version of the bestselling reference Handbook of Stem Cells, Two-Volume Set attempts to incorporate all the essential subject matter of the original two-volume edition in a single volume. The material has been reworked in an accessible format suitable for students and general readers interested in following the latest advances in stem cells, including full color presentation throughout. Although some extra language and chapters have been deleted, rigorous effort has been made to retain from the original two-volume set the material pertinent to the understanding of this exciting area of biology.The organization of the book remains largely unchanged, combining the prerequisites for a general understanding of adult and embryonic stem cells; the tools, methods, and experimental protocols needed to study and characterize stem cells and progenitor populations; as well as a presentation by the world's experts of what is currently known about each specific organ system.
    • Extracellular Matrix in Development and Disease

      • 1st Edition
      • Volume 15
      • November 18, 2005
      • English
      • Hardback
        9 7 8 0 4 4 4 5 1 8 4 6 0
      • eBook
        9 7 8 0 0 8 0 9 3 0 9 5 4
      Extracellular matrix proteins are serious, common human diseases that are caused by mutations in genes that encode these proteins. This has spurred a great number of researchers to study the extracellular matrix, sometimes by choice and sometimes by necessity. Much progress has been made in the last decade towards understanding what matrix proteins do and how cells interact with and respond to them. Volume 15 is a compilation of reviews by experts in their respective fields. The chapters in this book address the biology of a broad spectrum of extracellular matrix molecules and their functions in development and disease. This book has been designed to focus on a diverse subset of matrix proteins that have been shown to be important for development, function, and disease. The book therefore both presents a broad view of the field and provides crucial details about some of the best-studied matrix molecules.
    • Landmark Papers in Clinical Chemistry

      • 1st Edition
      • November 15, 2005
      • Richard M. Rocco
      • English
      • Paperback
        9 7 8 0 4 4 4 5 4 7 5 0 7
      • Hardback
        9 7 8 0 4 4 4 5 1 9 5 0 4
      • eBook
        9 7 8 0 0 8 0 4 5 8 9 4 6
      This is the first major review of the developments in clinical laboratory science in the 20th century presented in the words of the original inventors and discoverers. Introductory comments by the editor help place the works within the historical context.Landmark Papers addresses:*The origin of the home pregnancy test available today in every drugstore*The woman who invented a billion dollar technology, refused to patent it and went on to win a Nobel Prize*The scientists who worked on the US Government’s crash program at the start of WWII to find a substitute for the malaria drug quinine*The blood test used to monitor the effectiveness of cholesterol lowering drugs that today are taken by over 20 million patients*The graduate student who invented a technology for testing for infectious diseases, took it to Africa to screen people for malaria for the first time and which is now used to test for HIV infection world-wide*The invention of molecular diagnostics by Linus Pauling and the road to individualized medicine*The development of the glucose meter used by diabetics up to six times a day to monitor their metabolic control
    • Gene Therapy of the Central Nervous System: From Bench to Bedside

      • 1st Edition
      • November 11, 2005
      • Michael G. Kaplitt + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 4 1 5 6 9 6 8
      • eBook
        9 7 8 0 0 8 0 4 5 4 3 7 5
      Few areas of biomedical research provide greater opportunities for radically new therapies for devastating diseases that have evaded treatment so far than gene therapy. This is particularly true for the brain and nervous system, where gene transfer has become a key technology for basic research and has recently been translated to human therapy in several landmark clinical trials. Gene Therapy of the Central Nervous System: From Bench to Bedside represents the first definitive volume on this subject. Edited by two pioneers of neurological gene therapy, this volume contains contributions by leaders who helped create this field and are expanding the promise of gene therapy for the future of basic and clinical neuroscience. Drawing upon this extensive collective experience, this book provides clear and informative reviews on a variety of subjects of interest to anyone exploring or using gene therapy for neurobiological applications in research and clinical praxis.