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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • DNA Microarrays, Part A: Array Platforms and Wet-Bench Protocols

      • 1st Edition
      • Volume 410
      • August 28, 2006
      • English
      • Hardback
        9 7 8 0 1 2 1 8 2 8 1 5 8
      • eBook
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      Modern DNA microarray technologies have evolved over the past 25 years to the point where it is now possible to take many million measurements from a single experiment. These two volumes, Parts A & B in the Methods in Enzymology series provide methods that will shepard any molecular biologist through the process of planning, performing, and publishing microarray results. Part A starts with an overview of a number of microarray platforms, both commercial and academically produced and includes wet bench protocols for performing traditional expression analysis and derivative techniques such as detection of transcription factor occupancy and chromatin status. Wet-bench protocols and troubleshooting techniques continue into Part B. These techniques are well rooted in traditional molecular biology and while they require traditional care, a researcher that can reproducibly generate beautiful Northern or Southern blots should have no difficulty generating beautiful array hybridizations. Data management is a more recent problem for most biologists. The bulk of Part B provides a range of techniques for data handling. This includes critical issues, from normalization within and between arrays, to uploading your results to the public repositories for array data, and how to integrate data from multiple sources. There are chapters in Part B for both the debutant and the expert bioinformatician.
    • Regenerative Biology and Medicine

      • 1st Edition
      • August 28, 2006
      • David L. Stocum
      • English
      • eBook
        9 7 8 0 0 8 0 4 9 3 0 2 2
      The purpose of the book is to bring together in one place the different facets of regenerative biology and medicine while providing the reader with an overview of the basic and clinically-oriented research that is being done. Not only does the content cover a plethora tissues and systems, it also includes information about the developmental plasticity of adult stem cells and the regeneration of appendages.As part of its balanced presentation, Regenerative Biology and Medicine does address the biological/bioethica... issues and challanges involved in the new and exciting field of regenerative biology and medicine.
    • Developmental Genetics of the Flower

      • 1st Edition
      • Volume 44
      • August 25, 2006
      • English
      • Hardback
        9 7 8 0 1 2 0 0 5 9 4 4 7
      • eBook
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      Current major interests in this area include the study of higher level phylogenetic relationships and character evolution in the angiosperms, floral evolution, the genetic basis of key floral differences in basal angiosperms, the genetic and genomic consequences of polyploid speciation, conservation genetics of rare plant species, and phylogeography. Developmental Genetics of the Flower provides a series of papers focused on the developmental genetics of flowering as well as the genetic control of the timing of flowering. Investigation of speciational mechanisms, evolutionary relationships, and character evolution in flowering plants and land plants utilizing a variety of experimental approaches are discussed. The chapters are excellent reviews of the current fast-moving area of research.
    • Advances in Clinical Chemistry

      • 1st Edition
      • Volume 42
      • August 24, 2006
      • English
      • Paperback
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      • Hardback
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      Volume forty-two in the internationally acclaimed Advances in Clinical Chemistry series, contains chapters submitted from leading experts from academia and clinical laboratory science. Authors are from a diverse field of clinical chemistry disciplines and diagnostics ranging from basic biochemical exploration to cutting edge microarray technology. In keeping with the tradition of the series, this volume emphasizes novel laboratory advances with application not only to both clinical laboratory diagnostics, but as well as practical basic science studies. This volume of Advances in Clinical Chemistry is an indispensable resource and practical guide for twenty-first century practitioners of clinical chemistry, molecular diagnostics, pathology, and clinical laboratory sciences in general.
    • Hypothalamic Integration of Energy Metabolism

      • 1st Edition
      • Volume 153
      • August 21, 2006
      • A. Kalsbeek + 5 more
      • English
      • Hardback
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      • eBook
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      The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition. Research in this area has grown substantially and includes the neurochemical pathways of the hypothalamus and its role in regulating energy expenditures in the body. This volume in the Progress in Brain Research series examines the emerging role of the hypothalamus as a crucial link between the sensing of nutrients and the control of insulin sensitivity, glucose uptake, and glucose production, the integrative role of the hypothalamus in thyroid and bone metabolism, the interaction between circadian information and energy metabolism, and the important interplay between the immune system and energy metabolism.
    • Bioinformatics

      • 1st Edition
      • Volume 6
      • August 15, 2006
      • Dilip K Arora + 2 more
      • English
      • Paperback
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      • Hardback
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      • eBook
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      The advances in genomic technologies, such as microarrays and high throughput sequencing,have expanded the realm of possibilities for capturing data and analyzing it using automatedcomputer driven bioinformatics tools. With the completion of the sequencing of genomes ofhuman and several model organisms, a quest for scientific discoveries being fueled byintegrative and multidimensional techniques in mathematics and computational sciences. Inthis volume, leading researchers and experts have provided an overview of significantconcepts from biological, mathematical, and computational perspectives. It provides a high level view of fungal genomic data integration and annotation, classification of proteins and identification of vaccine targets, identification of secretome or secreted proteins in fungal genomes, as well as tools for analyzing microarray expressionprofiles.
    • New Transcription Factors and Their Role in Diabetes and Therapy

      • 1st Edition
      • Volume 5
      • August 10, 2006
      • Jacob E. Friedman
      • English
      • Hardback
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      This book contains contributions from some of the most eminent experts in the fields of genetics, biochemistry, and pathophysiology of diabetes. Through specific examples, with broad applications, this book provides a comprehensive look at how transcription factors may underline the pathogenetic mechanisms of diabetes and obesity. Volume 5 provides an overview of the status of the field, while also providing valuable information of practical utility to those who do not necessarily work in this field. The integration of basic biology with physiologically and clinically relevant proteins should provide the reader with a theoretical background to understanding the strategies for new potential therapeutic targets and their application to disease.
    • Progress in Nucleic Acid Research and Molecular Biology

      • 1st Edition
      • Volume 81
      • August 9, 2006
      • Kivie Moldave
      • English
      • eBook
        9 7 8 0 0 8 0 4 6 5 0 0 5
      Nucleic acids are the fundamental building blocks of DNA and RNA and are found in virtually every living cell. Molecular biology is a branch of science that studies the physicochemical properties of molecules in a cell, including nucleic acids, proteins, and enzymes. Increased understanding of nucleic acids and their role in molecular biology will further many of the biological sciences including genetics, biochemistry, and cell biology. Progress in Nucleic Acid Research and Molecular Biology is intended to bring to light the most recent advances in these overlapping disciplines with a timely compilation of reviews comprising each volume.
    • Biotechnology Annual Review

      • 1st Edition
      • Volume 12
      • August 8, 2006
      • M. Raafat El-Gewely
      • English
      • Hardback
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      • Paperback
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      Biotechnology is a diverse, complex and rapidly evolving field. Students and experienced researchers alike face the challenges of staying on top of developments in their field of specialty and maintaining a broader overview of the field as a whole. Volumes containing competent reviews on a diverse range of topics in the field fulfill the dual role of broadening and updating biotechnologists’ knowledge. The current volume is an excellent example of such a book. The topics covered range from classical issues in biotechnology - such as, recent advances in all-protein chromophore technology- to topics that are focused on coencapsulation of hepatocytes and bone marrow cell. The information presented in this book will therefore will be of great value to both experienced biotechnologists and biotechnologists in training.
    • Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals

      • 1st Edition
      • August 8, 2006
      • Ajit Sadana
      • English
      • Hardback
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      The application of biosensors is expanding in different areas. These are portable and convenient devices that permit the rapid, accurate, and reliable detection of analytes of interest present either in the atmosphere or in aqueous or in liquid phases. The detection of glucose levels in blood for the effective management of diabetes is one. Though different biosensors have been designed for an increasing number of applications, the kinetics of binding (and dissociation) of analytes by the receptors on the biosensor surfaces has not been given enough attention in the open literature. This is a very important area of investigation since it significantly impacts biosensor performance parameters such as stability, sensitivity, selectivity, response time, regenerability, etc. Binding and Dissociation Kinetics for Different Biosensor Applications Using Fractals addresses this critical need besides helping to correct or demonstrate the need to modify the present software available with commercial biosensors that determines the kinetics of analyte-receptor reactions on biosensor surfaces.