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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

    • Histone Deacetylase Inhibitors as Cancer Therapeutics

      • 1st Edition
      • Volume 116
      • November 1, 2012
      • English
      • Hardback
        9 7 8 0 1 2 3 9 4 3 8 7 3
      • eBook
        9 7 8 0 1 2 3 9 4 6 0 8 9
      Advances in Cancer Research provides invaluable information on the exciting and fast-moving field of cancer research. This thematic volume looks at "Histone Deacetylase Inhibitors as Cancer Therapeutics."
    • Advances in Genetics

      • 1st Edition
      • Volume 80
      • November 1, 2012
      • English
      • eBook
        9 7 8 0 1 2 4 0 4 7 4 3 3
      The field of genetics is rapidly evolving, and new medical breakthroughs are occurring as a result of advances in our knowledge of genetics. This series continually publishes important reviews of the broadest interest to geneticists and their colleagues in affiliated disciplines.
    • Open Source Software in Life Science Research

      • 1st Edition
      • October 31, 2012
      • Lee Harland + 1 more
      • English
      • Hardback
        9 7 8 1 9 0 7 5 6 8 9 7 8
      • eBook
        9 7 8 1 9 0 8 8 1 8 2 4 9
      The free/open source approach has grown from a minor activity to become a significant producer of robust, task-orientated software for a wide variety of situations and applications. To life science informatics groups, these systems present an appealing proposition - high quality software at a very attractive price. Open source software in life science research considers how industry and applied research groups have embraced these resources, discussing practical implementations that address real-world business problems.The book is divided into four parts. Part one looks at laboratory data management and chemical informatics, covering software such as Bioclipse, OpenTox, ImageJ and KNIME. In part two, the focus turns to genomics and bioinformatics tools, with chapters examining GenomicsTools and EBI Atlas software, as well as the practicalities of setting up an ‘omics’ platform and managing large volumes of data. Chapters in part three examine information and knowledge management, covering a range of topics including software for web-based collaboration, open source search and visualisation technologies for scientific business applications, and specific software such as DesignTracker and Utopia Documents. Part four looks at semantic technologies such as Semantic MediaWiki, TripleMap and Chem2Bio2RDF, before part five examines clinical analytics, and validation and regulatory compliance of free/open source software. Finally, the book concludes by looking at future perspectives and the economics and free/open source software in industry.
    • Genomic and Personalized Medicine

      • 2nd Edition
      • October 30, 2012
      • Geoffrey S. Ginsburg + 1 more
      • English
      • eBook
        9 7 8 0 1 2 3 8 2 2 2 8 4
      Genomic and Personalized Medicine, Second Edition — winner of a 2013 Highly Commended BMA Medical Book Award for Medicine — is a major discussion of the structure, history, and applications of the field, as it emerges from the campus and lab into clinical action. As with the first edition, leading experts review the development of the new science, the current opportunities for genome-based analysis in healthcare, and the potential of genomic medicine in future healthcare. The inclusion of the latest information on diagnostic testing, population screening, disease susceptability, and pharmacogenomics makes this work an ideal companion for the many stakeholders of genomic and personalized medicine. With advancing knowledge of the genome across and outside protein-coding regions of DNA, new comprehension of genomic variation and frequencies across populations, the elucidation of advanced strategic approaches to genomic study, and above all in the elaboration of next-generation sequencing, genomic medicine has begun to achieve the much-vaunted transformative health outcomes of the Human Genome Project, almost a decade after its official completion in April 2003.
    • Handbook of Proteolytic Enzymes

      • 3rd Edition
      • October 30, 2012
      • Alan J. Barrett + 2 more
      • English
      • eBook
        9 7 8 0 1 2 3 8 2 2 2 0 8
      Extensively revised and updated, the new edition of the highly regarded Handbook of Proteolytic Enzymes is an essential reference for biochemists, biotechnologists and molecular biologists. Edited by world-renowned experts in the field, this comprehensive work provides detailed information on all known proteolytic enzymes to date. This two-volume set unveils new developments on proteolytic enzymes which are being investigatedin pharmaceutical research for such diseases as HIV, Hepatitis C, and the common cold. Volume I covers aspartic and metallo petidases while Volume II examines peptidases of cysteine, serine, threonine and unknown catalytic type. A CD-ROM accompanies the book containing fully searchable text, specialised scissile bond searches, 3-D color structures and much more.
    • Pediatric Endocrinology, An Issue of Endocrinology and Metabolism Clinics

      • 1st Edition
      • Volume 41-4
      • October 26, 2012
      • Robert Rapaport
      • English
      • Hardback
        9 7 8 1 4 5 5 7 4 8 4 1 9
      • eBook
        9 7 8 1 4 5 5 7 4 8 4 2 6
      This issue of Endocrinology and Metabolism Clinics provides essential updates across the spectrum of pediatric endocrinology. Topics covered include Prevention of type 1 and type 2 diabetes mellitus; genetics of growth; diagnosis in prepubescent girls; Turner and Noonan Syndromes; thyroid function in Down Syndrome; chronic disease; effects of ADHD treatment on growth; Vitamin D and bone health; use of statins; and obesity prevention.
    • Biocompatibility and Performance of Medical Devices

      • 1st Edition
      • October 26, 2012
      • Jean-Pierre Boutrand
      • English
      • Paperback
        9 7 8 0 0 8 1 0 1 5 7 0 4
      • Hardback
        9 7 8 0 8 5 7 0 9 0 7 0 6
      • eBook
        9 7 8 0 8 5 7 0 9 6 4 5 6
      Implant and device manufacturers are increasingly facing the challenge of proving that their products are safe and biocompatible, and that they will perform as expected. Biocompatibility and performance of medical devices provides an essential guide to the performance analysis of these vital devices.Part one introduces the key concepts and challenges faced in relation to biocompatibility in medical devices, with consideration of biological safety evaluation planning and biomechanical and biochemical compatibility in innovative biomaterials. Part two goes on to discuss the evaluation and characterisation of biocompatibility in medical devices. Topics covered include material and chemical characterisation, allowable limits for toxic leachables, in vivo and in vitro testing and blood compatibility assessment. Testing and interpreting medical device performance is the focus of part three, with chapters describing preclinical performance studies for bone, dental and soft tissue implants, and mechanical testing of soft and hard tissue implants. Part four provides information on the regulation of medical devices in the European Union, Japan and China, and the book concludes with part five, a review of histopathology principles for biocompatibility and performance studies.With its distinguished editor and international team of expert contributors, Biocompatibility and performance of medical devices is a vital tool for all those involved in the research, design, production and application of medical devices, including research directors, production companies and medical regulatory agencies, as well as industry professionals and academics.
    • Biomaterials Science

      • 3rd Edition
      • October 25, 2012
      • Buddy D. Ratner + 3 more
      • English
      • Hardback
        9 7 8 0 1 2 3 7 4 6 2 6 9
      • eBook
        9 7 8 0 0 8 0 8 7 7 8 0 8
      The revised edition of this renowned and bestselling title is the most comprehensive single text on all aspects of biomaterials science. It provides a balanced, insightful approach to both the learning of the science and technology of biomaterials and acts as the key reference for practitioners who are involved in the applications of materials in medicine.
    • Eukaryotic RNases and their Partners in RNA Degradation and Biogenesis

      • 1st Edition
      • Volume 31
      • October 16, 2012
      • English
      • Hardback
        9 7 8 0 1 2 4 0 4 7 4 0 2
      • eBook
        9 7 8 0 1 2 4 0 4 7 4 5 7
      This special issue of The Enzymes is targeted towards researchers in biochemistry, molecular and cell biology, pharmacology, and cancer. This volume discusses Eukaryotic RNases and their partners in RNA degradation and biogenesis.
    • Autophagy in Health and Disease

      • 1st Edition
      • October 16, 2012
      • Roberta A. Gottlieb
      • English
      • Hardback
        9 7 8 0 1 2 3 8 5 1 0 1 7
      • eBook
        9 7 8 0 1 2 3 8 5 1 0 2 4
      Autophagy in Health and Disease offers an overview of the latest research in autophagy with a translational emphasis. This publication takes scientific research in autophagy a step further and offers integrated content with advancements in autophagy from cell biology and biochemical research to clinical treatments. A necessary reference for the bookshelf of medical and scientific researchers and students, Autophagy in Health and Disease presents high quality, reputable information on autophagy, allowing the reader quick access to the most applicable information.