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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Speech Enhancement

      • 1st Edition
      • January 4, 2014
      • Jacob Benesty + 3 more
      • English
      • Paperback
        9 7 8 0 1 2 8 0 0 1 3 9 4
      • eBook
        9 7 8 0 1 2 8 0 0 2 5 3 7
      Speech enhancement is a classical problem in signal processing, yet still largely unsolved. Two of the conventional approaches for solving this problem are linear filtering, like the classical Wiener filter, and subspace methods. These approaches have traditionally been treated as different classes of methods and have been introduced in somewhat different contexts. Linear filtering methods originate in stochastic processes, while subspace methods have largely been based on developments in numerical linear algebra and matrix approximation theory. This book bridges the gap between these two classes of methods by showing how the ideas behind subspace methods can be incorporated into traditional linear filtering. In the context of subspace methods, the enhancement problem can then be seen as a classical linear filter design problem. This means that various solutions can more easily be compared and their performance bounded and assessed in terms of noise reduction and speech distortion. The book shows how various filter designs can be obtained in this framework, including the maximum SNR, Wiener, LCMV, and MVDR filters, and how these can be applied in various contexts, like in single-channel and multichannel speech enhancement, and in both the time and frequency domains.

    • Current Topics in Bioenergetics

      • 1st Edition
      • June 28, 2014
      • C. P. Lee
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 3 5 5 3
      • eBook
        9 7 8 1 4 8 3 2 1 6 9 8 0
      Current Topics in Bioenergetics, Volume 14 provides information pertinent to the structure and function relationship of energy-transducing membranes. This book presents a number of biochemical and biophysical approaches that are valuable in some systems. Organized into five chapters, this volume begins with an overview of cytochrome oxidase, a noncrystallizable membrane protein. This text then determines the interaction of small organic molecules with biological membranes on a molecular level. Other chapters consider the various physical techniques that are used to investigate the structural and dynamic properties of proteins, lipids, and membranes, including neutron diffraction, X-ray diffraction, electron microscopy, optical rotatory dispersion, nuclear magnetic resonance, fluorescence spectroscopy, and Raman spectroscopy. This book discusses as well the biological importance of metal ions. The final chapter deals with optical activity spectroscopy as a recognized tool for the examination of the conformation of biological macromolecules. This book is a valuable resource for biochemists, biophysicists, and biologists.

    • The Cell Surface: Mediator of Developmental Processes

      • 1st Edition
      • May 10, 2014
      • Stephen Subtelny + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 0 2 4
      • eBook
        9 7 8 1 4 8 3 2 7 1 9 1 0
      The Cell Surface: Mediator of Developmental Processes contains the papers presented at the 38th Symposium of the Society for Developmental Biology, held at the University of British Columbia in Vancouver, Canada in June 1979. The compendium is divided into three parts. The first part provides a summary of the status of the knowledge about the cell surface, which includes the plasma membrane, its associated cytoskeleton and the variety of surface-associated macromolecules. The second portion focuses on the early development of the cell surface. A wide spectrum of techniques, systems, and results in the study of the cell surface are presented. The last part shows a variety of experimental systems in which the cell surface figures prominently in important developmental events. The results from experiments on plant symbiosis, mammalian teratocarcinomas, adhesion and cell shape, and various extracellular macromolecules are detailed extensively. Cytologists, microbiologists, biologists, and other scientists in allied fields will find the publication very insightful.

    • The Antigens

      • 1st Edition
      • May 10, 2014
      • Michael Sela
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 6 4 6 8
      • eBook
        9 7 8 1 4 8 3 2 6 9 5 7 3
      The Antigens, Volume V is a comprehensive treatise covering all aspects of antigens, including their chemistry and biology as well as their immunologic role and expression. Four complex problems of direct relevance to human health are explored, namely, tumor antigens, antigens of helminths, cytotoxic lymphocytes, and complement. Comprised of four chapters, this volume begins with a review of classic studies of tumor-specific transplantation antigens, followed by a discussion on the detection and purification of tumor antigens; the immune response to tumor antigens; and the role of tumor antigens in the escape of tumors from immunological control. The reader is then introduced to some aspects of the different functions of antigens of helminths, along with the immune response in helminthiasis. The book also examines the generation, properties, and mode of action of antibody-independent cytolytic T lymphocytes before concluding with an analysis of the complement system and its reaction pathways as well as its role as an autoantigen. This monograph will be of interest to practitioners and researchers in immunology, experimental and clinical medicine, biochemistry, and other disciplines.

    • Cholinergic Ligand Interactions

      • 1st Edition
      • June 28, 2014
      • D. J. Triggle + 2 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 4 7 6 9 4
      • eBook
        9 7 8 1 4 8 3 2 7 6 5 6 4
      Cholinergic Ligand Interactions presents the papers read at a symposium held at the State University of New York at Buffalo, 25-26 May 1970. The recent purification and crystallization of acetylcholinesterase together with real progress in the purification of receptor components indicated the desirability of organizing a symposium to discuss not only these aspects but also the structural bases for cholinergic ligand interaction with these macromolecules, the conformational changes involved with ligand binding, the quantitation of cholinergic ligand binding sites, and the roles of acetylcholinesterase and its isozymes in muscle disease. The volume contains nine chapters and begins with a study on possible conformational changes in acetylcholinesterase... This is followed by separate chapters on the subunits of acetylcholinesterase... in vitro studies with the cholinergic receptor of the eel electroplax; identification and isolation of acetylcholine receptors; assay and properties of essential (junctional) cholinesterases of the rat diaphragm; and structural variations in cholinergic ligands. Subsequent chapters deal with ligand interactions at the muscarinic receptors and changes in cholinesterases isozymes during normal and dystrophic muscle development.

    • Enzymology in the Practice of Laboratory Medicine

      • 1st Edition
      • May 10, 2014
      • Philip Blume + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 3 6 3 7 7
      • eBook
        9 7 8 1 4 8 3 2 7 7 7 0 7
      Enzymology in the Practice of Laboratory Medicine focuses on disease processes, enzymatic reactions and activities, and diagnosis and management of diseases. The selection first offers information on developments in the search for mechanisms of enzymic catalysis; application of the spin labeling technique to biological membranes; and the properties of membrane bound enzymes involved in energy transduction processes. Discussions focus on possible clinical interrelationships of membrane function, mitochondrial membrane transactions, mechanical details of chymotryptic catalysis, and physical nature of globular proteins. The text then elaborates on metalloenzymes, enzyme measurement, and enzymology, clinical chemistry, and development of fast analyzers. The publication examines the analytical uses of immobilized enzymes; origin of serum enzymes and the basis for their variation; and the screening methods for glycolytic enzyme deficiencies in red blood cells. Topics include factors contributing to normal variation of enzyme activity, catabolism of enzymes, mechanism of release from cells to plasma, and determination of urea in blood and urine. The selection is a dependable reference for researchers interested in the application of enzymology in laboratory medicine.

    • Pyruvate and Fatty Acid Metabolism

      • 1st Edition
      • Volume 18
      • June 28, 2014
      • Marcel Florkin + 1 more
      • English
      • eBook
        9 7 8 1 4 8 3 1 9 3 1 6 8
      Comprehensive Biochemistry, Volume 18S: Pyruvate and Fatty Acid Metabolism focuses on the processes, methodologies, principles, and reactions involved in pyruvate and fatty acid metabolism, including broad outlines of the metabolism of amino acids, proteins, carbohydrates, lipids, and their derived products. The selection first ponders on pyruvate dehydrogenase complex and citric acid cycle. Numerical analyses of the various reaction sequences are presented. The text also takes a look at fatty acid metabolism. Discussions focus on fatty acid oxidation and biosynthesis, elongation and desaturation of fatty acids, and control of fatty acid oxidation and biosynthesis. The book is a valuable reference for researchers interested in pyruvate and fatty acid metabolism.

    • Recombinant DNA Laboratory Manual

      • 1st Edition
      • May 12, 2014
      • Judith W. Zyskind + 1 more
      • English
      • Paperback
        9 7 8 1 4 8 3 2 0 7 5 4 4
      • eBook
        9 7 8 1 4 8 3 2 2 0 9 7 0
      Recombinant DNA Laboratory Manual is a laboratory manual on the fundamentals of recombinant DNA techniques such as gel electrophoresis, in vivo mutagenesis, restriction mapping, and DNA sequencing. Procedures that are useful for studying either prokaryotes or eukaryotes are discussed, and experiments are included to teach the fundamentals of recombinant DNA technology. Hands-on computer sessions are also included to teach students how to enter and manipulate sequence information. Comprised of nine chapters, this book begins with an introduction to bacterial growth parameters, how to measure bacterial cell growth, and how to plot cell growth data. The discussion then turns to the isolation and analysis of chromosomal DNA in bacteria and Drosophila; plasmid DNA isolation and agarose gel analysis; and introduction of DNA into cells. Subsequent chapters deal with Tn5 mutagenesis of pBR329; DNA cloning in M13; DNA sequencing; and DNA gel blotting, probe preparation, hybridization, and hybrid detection. The book concludes with an analysis of lambda phage manipulations. This manual is intended for advanced undergraduate or beginning graduate students and should also be helpful to established investigators who are changing their research focus.

    • Regulatory Affairs for Biomaterials and Medical Devices

      • 1st Edition
      • October 10, 2014
      • Stephen F. Amato + 1 more
      • English
      • Hardback
        9 7 8 0 8 5 7 0 9 5 4 2 8
      • Paperback
        9 7 8 0 0 8 1 0 1 5 3 3 9
      • eBook
        9 7 8 0 8 5 7 0 9 9 2 0 4
      All biomaterials and medical devices are subject to a long list of regulatory practises and policies which must be adhered to in order to receive clearance. This book provides readers with information on the systems in place in the USA and the rest of the world. Chapters focus on a series of procedures and policies including topics such as commercialization, clinical development, general good practise manufacturing and post market surveillance.

    • Physiology and Biochemistry

      • 2nd Edition
      • February 12, 2014
      • Geoffrey Bourne
      • English
      • Paperback
        9 7 8 0 1 2 3 9 4 1 6 3 3
      • eBook
        9 7 8 0 3 2 3 1 6 1 5 5 8
      The Structure and Function of Muscle, Second Edition, Volume III: Physiology and Biochemistry presents the physiology and biochemistry of muscle. This book discusses the various aspects of the structure of muscles and explores some aspects of muscle disease. Organized into 10 chapters, this edition begins with an overview of the transverse tubular system or T system of striated muscle. This text then examines the properties and function of membranes through electron microscopy. Other chapters consider in more detail from a biophysical viewpoint certain aspects of the series of events surrounding muscle contraction. This book discusses as well the significance of the central circulation and the amount of oxygen that can be delivered by the cardiovascular system. The final chapter deals with the heat output and chemical breakdown during an isometric twitch. This book is a valuable resource for scientists, neurobiologists, biologists, biochemists, physiologists, histologists, cytologists, and research workers.

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