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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

  • Cutting-edge Computational Intelligence in Healthcare with Convolution and Kronecker Convolution-based Approaches

    • 1st Edition
    • Allam Jaya Prakash + 2 more
    • English
    Cutting-edge Computational Intelligence in Healthcare with Convolution and Kronecker Convolution-based Approaches focuses on the use of deep learning techniques in the field of medical imagine analysis. These advances offer promising progress in healthcare through improvements in diagnostic accuracy, efficiency in medical image interpretation, and breakthroughs in treatment planning. Divided into five sections, the book begins with foundational coverage of deep learning in medical imaging and fundamentals of Convolutional Neural Networks. Discover the role convolutions play in extracting meaningful features from images, aiding tasks such as diagnosis and segmentation. The second section takes a deep dive into Kronecker convolutions and their unique advantages, such as enhanced spatial hierarchy understanding, efficient parameter utilization, and improved adaptability to specific characteristics of medical images. Section three reviews specific applications in tumor detection, enhancing organ segmentation as well as disease classification, and section four explores real-world implementation of AI-driven diagnostic imaging, precision medicine via imaging analytics, and wearable devices and continuous health monitoring. The final section offers discussion on the unique challenges, trends, and potential future directions these innovative computational approaches have on medical image processing and advanced healthcare. In summary, this book takes an interdisciplinary approach to bridge the gap between theory and practice, fusing knowledge from the domains of medicine, computer science, and machine learning to address issues in healthcare through sophisticated image analysis techniques.
  • Clinical Research in Private Practice

    • 1st Edition
    • Jason E. Pope + 3 more
    • English
    Clinical research is the tip of the spear for innovation and central in the development of improving safety and efficacy for patient centric care. Unfortunately, clinical research in academic practices is bogged down by inefficiency and infrequent regulatory oversight, thus leaving physicians unable to meet the clinical and research needs for driving innovation. Private practice is a valid practice cohort that can effectively, reliably, and reproducibly perform study related activities, for both FDA and non-FDA regulated studies, both industry-sponsored or investigator-initiat... Research in Private Practice fills a gap and provides a playbook for how to incorporate clinical research in a validated, safe, and compliant manner, allowing a needed meaningful contribution to the medical space, while concurrently maintaining fiduciary responsibility. Written for physicians by physicians.
  • Design and Applications of Cell-Free Systems Part A

    • 1st Edition
    • Volume 218
    • English
    Design and applications of cell-free systems –Part A represents an important component in the field of biochemistry, duly acknowledging the pioneering effort made by Nobel laureate Eduard Buchner for discovery of fermentation in yeast cell extracts (YCE). CFS requires a core molecular machinery including RNA polymerase, translational apparatus (ribosomes, tRNA synthases, and translation factors), energy-generating molecules, and their cofactors, substrates, and DNA or plasmid templates for obtaining desired products. CFS is a simple, rapid, and sensitive platform, which is devoid of membrane-bound barriers, yet contains all the mandatory substrates, biomolecules, and machineries required for the synthesis of the desired proteins. It has the potential to overcome loopholes in the current in vivo production systems and it is promising tool in both basic and applied scientific research. It facilitates a simplified organization of desired experiments with a variety of reaction conditions, making CFS a powerful tool in biological and translational science research.This volume offers wide range of topics on different aspects of cell free systems design and their applications. It covers introduction to applications of cell-free systems, protocol for cell free design, transcription and translation, computational biology, artificial intelligence, automation and robotics for cell free systems, cell free for biosensor, low cost diagnostics, cell free based high throughput screening, biodesign and incorporation of non-natural amino acids into proteins. This volume helps students, researchers, scientists, clinicians, stakeholders, policymakers, and practitioners to understand cell-free systems and their applications in many areas.
  • Genetic Regulation of Immune Response Pathways

    • 1st Edition
    • Volume 115
    • English
    Genetic Regulation of Immune Response Pathways, Volume 115 in the Advances in Genetics series, highlights new advances in the field, with this new volume presenting comprehensive chapters on a variety of timely topics. Chapters explore the genetic regulation of immune cells upon activation, IFN response regulation during viral infections, and the role of noncoding RNAs—including lncRNAs and ncRNAs—in immune regulation and inflammation. Additional sections examine the JAK-STAT signaling pathway in inflammatory and autoimmune diseases as a potential therapeutic target, long noncoding RNAs as key regulators of autoimmunity, and the importance of appropriate cytokine expression in maintaining immune response homeostasis.Together... these contributions provide valuable insights into the molecular and genetic mechanisms underlying immune-mediated processes.
  • Advances in Clinical Chemistry

    • 1st Edition
    • Volume 130
    • English
    Advances in Clinical Chemistry series, highlights new advances in the field, with this new volume presenting interesting chapters. Each chapter is written by an international board of authors. This volume provides invaluable information on the fast-moving field of chemistry research that includes outstanding original reviews on a variety of topics.
  • Transforming Global Healthcare Delivery

    Leveraging Technology to Increase Accessibility and Affordability
    • 1st Edition
    • Sandeep Reddy
    • English
    Transforming Global Healthcare Delivery: Leveraging Technology to Increase Accessibility and Affordability guides readers through the ongoing digital transformation of healthcare. The author makes the case for how tools like AI, telehealth, and data analytics can empower patients, connect underserved communities, and help health systems achieve the Quadruple Aim. Real-world examples along with the author's evaluations of digital health interventions showcase promising directions. The author argues realizing the full potential of new technologies requires corresponding advancement of care delivery models towards team-based, coordinated practice and spotlights innovative programs trailing shared appointments, community health workers, remote monitoring and more that can expand access and better meet individual needs. With authoritative analysis grounded in both research and practice, this book serves as a practical roadmap for digitally enabled, patient-centred care capable of delivering improved outcomes to all. Dr. Reddy has over 25 years of international experience as a clinician, researcher, and health system leader; offering an unmatched perspective on leveraging technology to enable patient-centred, value-based care. Transforming Global Healthcare Delivery: Leveraging Technology to Increase Accessibility and Affordability draws on extensive qualifications across medicine, public health, management, and informatics.
  • Antimicrobial Peptides and Proteins

    • 1st Edition
    • Volume 149
    • English
    Antimicrobial Peptides and Proteins, Volume 149 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters on topics such as Nature and mechanistic action of Antimicrobial Peptides, Advances in elucidation molecular targets and mechanisms of action of AMPs: beyond membrane disruption, Discovery, Design, and Applications of Antimicrobial Peptides, Designing Potent Antimicrobial Peptides Against Acinetobacter baumannii: A Combined Approach Using Genetic Algorithms and Machine Learning Strategies, Protection of Diabetic Wound Patients from Invasive Bacterial Infections by Innate Antimicrobial Peptides, and more.Additional chapters explore Bacteriophage Lysins as a potential therapeutic strategy for Methicillin Resistant Staphylococcus aureus infections, Structural insights and therapeutic potential of host defense peptides in combatting antimicrobial resistance, Antimicrobial protein as a cargo for antimicrobial nanomaterials to combat Gram-negative bacteria, Unravelling the Role of Antimicrobial Proteins in Leptospirosis: A Comprehensive Transcriptomic Analysis, and Deciphering Antimicrobial Peptide (AMP) Resistance Mechanisms in Enterococcus faecalis Through Integrated RNA-Seq and Hub Genes Identification.
  • Current Trends in Breast Cancer Pathology, Screening, Diagnosis and Treatments

    • 1st Edition
    • Firdos Alam Khan
    • English
    Current Trends in Breast Cancer Pathology, Screening, Diagnosis and Treatments offers an extensive examination of the intricate landscape of breast cancer. This reference not only traverses the entire spectrum from pathology to advanced treatment methodologies but also provides the complexities of bioinformatics research and basic research. By presenting information in a manner that is easily digestible, this book caters to researchers and students across various levels of expertise, facilitating a broader understanding of the subject. Spanning 12 detailed chapters, this book unravels the intricacies of breast cancer development. It provides insights into the cellular and molecular pathologies that underlie the disease, outlines the various stages of breast cancer, and elucidates the diverse methods employed in screening and diagnosis. Moreover, this book explores the available treatment modalities, offering a nuanced perspective on the challenges inherent in breast cancer diagnosis and treatment. This book goes beyond a retrospective analysis and adopts a forward-thinking approach. It not only addresses the current challenges but also casts a forward-looking gaze, identifying potential future research avenues in this critical field. This foresight is essential in shaping the trajectory of advancements in breast cancer research and treatment. Tailor-made for a broad audience, including health professionals, scientists, researchers, health practitioners, and students, its thorough examination of current paradigms ensures that readers gain a nuanced understanding of the complexities involved in breast cancer.
  • Revolutionizing Drug Development

    Harnessing AI and Computational Biology
    • 1st Edition
    • Jen-Tsung Chen
    • English
    Revolutionizing Drug Development: Harnessing AI and Computational Biology presents cutting-edge artificial intelligence (AI) tools, such as machine- and deep-learning models and generative AI, to assist structure-based drug design and clinical trial design and integrate with drug development programs. This book summarizes technical advancements of AI-based technologies and computational biology approaches, highlighting their applications in developing new drugs through discovery, repurposing, and designing, for advancing R&D in the pharmaceutical industry and benefiting precision medicine. This book serves as an ideal reference for students, teachers, professors, and researchers in biological and biomedical sciences, particularly the topics related to bioinformatics, systems biology, pharmacology, and drug development. The readers can efficiently and precisely overview this burning field, which might inspire their future directions of research in drug development and AI-based digital biology.
  • Deep Learning for Cardiac Signal Analysis in Robotic Applications

    • 1st Edition
    • Kapil Gupta + 1 more
    • English
    Deep Learning for Cardiac Signal Analysis in Robotic Applications delves into the transformative role of artificial intelligence in enhancing robotic-assisted cardiovascular procedures. Addressing the complexities of heart signal interpretation amidst the dynamic environment of cardiac surgery, this book meets the critical need for a comprehensive resource that bridges deep learning advances with practical surgical applications. It responds to the challenge of understanding intricate bio-signals, such as ECG, VCG, and BCG, by providing clear explanations, case studies, and methodological insights tailored to improve surgical precision, safety, and patient outcomes. The book is organized into three parts, starting with the fundamentals of cardiac signals and deep learning. It introduces key heart modalities, including the physiological underpinnings and challenges of signals like ECG and BCG, followed by an overview of deep learning architectures relevant to signal processing. Pre-processing and feature extraction techniques are detailed to prepare readers for advanced analysis. Part II focuses on AI-enhanced cardiac signal analysis, covering arrhythmia detection, myocardial ischemia diagnostics, hypertension monitoring via BCG, and explainable AI approaches for fetal arrhythmia monitoring. The final section integrates AI with robotic cardiac surgery, addressing real-time signal integration, AI-guided intervention precision, intraoperative decision support, postoperative monitoring, and future trends in cardiac AI and robotic-assisted surgery.This book is an invaluable resource for engineering students and academicians seeking to deepen their understanding of AI applications in healthcare. It equips readers with practical knowledge to tackle challenges in cardiac signal processing and robotic application, fostering interdisciplinary expertise that spans biomedical engineering, computer science, and clinical practice. This book not only advances academic research but also supports innovation in developing intelligent surgical systems and improving patient care.