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Books in Life sciences

Elsevier's Life Sciences collection helps researchers get comprehensive coverage and up-to-date information on the study of living organisms, their processes, and interrelationships, spanning disciplines like biology, genetics, and biochemistry, and addressing emerging trends such as genomics, biotechnology, and sustainability, essential for advancing knowledge and driving innovation in the field.

BooksJournals

    • Proteomic and Metabolomic Approaches to Biomarker Discovery

      • 2nd Edition
      • October 24, 2019
      • Haleem J. Issaq + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 6 0 7 7
      • eBook
        9 7 8 0 1 2 8 1 9 7 8 8 2
      Proteomic and Metabolomic Approaches to Biomarker Discovery, Second Edition covers techniques from both proteomics and metabolomics and includes all steps involved in biomarker discovery, from study design to study execution. The book describes methods and presents a standard operating procedure for sample selection, preparation and storage, as well as data analysis and modeling. This new standard effectively eliminates the differing methodologies used in studies and creates a unified approach. Readers will learn the advantages and disadvantages of the various techniques discussed, as well as potential difficulties inherent to all steps in the biomarker discovery process. This second edition has been fully updated and revised to address recent advances in MS and NMR instrumentation, high-field NMR, proteomics and metabolomics for biomarker validation, clinical assays of biomarkers and clinical MS and NMR, identifying microRNAs and autoantibodies as biomarkers, MRM-MS assay development, top-down MS, glycosylation-based serum biomarkers, cell surface proteins in biomarker discovery, lipodomics for cancer biomarker discovery, and strategies to design studies to identify predictive biomarkers in cancer research.

    • Pregnancy and the Pharmaceutical Industry

      • 1st Edition
      • May 24, 2019
      • Kristine E. Shields
      • English
      • Paperback
        9 7 8 0 1 2 8 1 8 5 5 0 6
      • eBook
        9 7 8 0 1 2 8 1 9 0 7 4 6
      Pregnancy and the Pharmaceutical Industry: The Movement towards Evidence-Based Care for Pregnant Women explores the issues surrounding the decision to undertake clinical trials with pregnant women. There is currently a lack of data on the safety and effectiveness of medications used during pregnancy as it is impossible to extrapolate that information from drug studies on men and non-pregnant women. As a majority of pregnant women confront a medical condition during their pregnancy, from simple pain, to ongoing or new medical issues, this book quantifies the current absence of pregnant women in drug studies and identifies ethical issues, barriers, litigation fears and opportunities. Those in the pharmaceutical industry, IRB members who approve or deny drug study plans, doctors, nurses and midwives working in obstetrics or involved in conducting studies at their institutions will find this book an essential resource.

    • Sports, Exercise, and Nutritional Genomics

      • 1st Edition
      • August 25, 2019
      • Debmalya Barh + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 1 9 3 7
      • eBook
        9 7 8 0 1 2 8 1 6 3 4 0 5
      Sports, Exercise, and Nutritional Genomics: Current Status and Future Directions is the first reference volume to offer a holistic examination of omics-driven advances across different aspects of exercise and sports physiology, biochemistry, sports medicine, psychology, anthropology, and sports nutrition; and highlighting the opportunities towards advance personalized training and athlete health management. More than 70 international experts from 14 countries have discussed key exercise and sport-related themes through the prism of genomics, epigenomics, transcriptomics, proteomics, metabolomics, telomere biology, talent in sport, individual differences in response to regular physical activity, that in the future may empower coaches, sports physicians, fitness experts, genetic counselors, and translational scientists to employ various omics data and approaches in improving health and physical performance of people participating in sports and exercise activities. Contributors address current knowledge of genetic influence on athletic performance, individual responses to exercise training, as well as the genetics of musculoskeletal phenotypes, exercise-related injuries, flexibility, and neurodegenerative disorders in athletes. Finally, performance-related and psychological traits associated with epigenetic, transcriptomic and metagenomic biomarkers are also considered, along with nutritional and pharmacogenomic aids in sports medicine and personalized nutrition.

    • Anorectal Disorders

      • 1st Edition
      • March 6, 2019
      • Enrique Coss-Adame + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 5 3 4 6 8
      • eBook
        9 7 8 0 1 2 8 1 5 3 4 7 5
      Anorectal Disorders: Diagnosis and Nonsurgical Treatments incorporates the most recent major advances in the understanding of anal and rectal anatomy to provide clinical evidence of care for those suffering from anorectal disorders. By condensing basic and practical aspects in the knowledge of anorectal disorders, this book provides a comprehensive review of the anatomy and physiology of the anorectal region. It includes new technology that expands and modifies current perceptions about the functional anatomy of the anorectal region and ultimately impacts how we conceive muscle and nerve structures functioning together to maintain fecal continence and properly execute the process of defecation. Perfect for medical researchers, gastroenterologists, general practitioners, internal medicine doctors and general surgeons, this title will provide diagnosis and treatment options for all patients suffering from anorectal disorders.

    • Patent Foramen Ovale Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia

      • 1st Edition
      • August 23, 2019
      • M. Khalid Mojadidi + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 9 6 6 7
      • eBook
        9 7 8 0 1 2 8 1 7 3 3 4 3
      Patent Foramen Ovale (PFO) Closure for Stroke, Myocardial Infarction, Peripheral Embolism, Migraine, and Hypoxemia is a complete reference covering the association between PFO and numerous medical conditions. It provides a background on the topic including embryology, anatomy, and physiology. This book fully examines the diagnosis and imaging assessment of PFO and discusses the data linking PFO to various clinical pathologies. It details technical aspects of PFO closure and includes perspectives on future outlooks and where the field is headed in terms of device closure indications. This is a complete reference book for cardiologists, interventional cardiologists, neurologists, pulmonologists, general practitioners, medical professionals, and researchers who are interested in PFO-associated pathologies, technical aspects, safety, and future outlooks of PFO device closure.

    • Animal Models in Cancer Drug Discovery

      • 1st Edition
      • April 16, 2019
      • Asfar Azmi + 1 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 4 7 0 4 7
      • eBook
        9 7 8 0 1 2 8 1 4 7 0 5 4
      Animal Models in Cancer Drug Discovery brings forward the most cutting-edge developments in tumor model systems for translational cancer research. The reader can find under this one volume virtually all types of existing and emerging tumor models in use by the research community. This book provides a deeper insight on how these newer models could de-risk modern drug discovery. Areas covered include up to date information on latest organoid derived models and newer genetic models. Additionally, the book discusses humanized animal tumor models for cancer immunotherapy and how they leverage personalized therapies. The chapter on larger animal, canine models and their use in and their use in pre-investigational new drug (pre-IND) development makes the volume unique. Unlike before, the incorporation of several simplified protocols, breeding methodologies, handling and assessment procedures to study drug intervention makes this book a must read. Animal Models in Cancer Drug Discovery is a valuable resource for basic and translational cancer researchers, drug discovery researchers, contract research organizations, and knowledge seekers at all levels in the biomedical field.

    • Rhinovirus Infections

      • 1st Edition
      • June 12, 2019
      • Nathan Bartlett + 2 more
      • English
      • Paperback
        9 7 8 0 1 2 8 1 6 4 1 7 4
      • eBook
        9 7 8 0 1 2 8 1 6 4 1 8 1
      Rhinovirus Infections: Rethinking the Impact on Human Health and Disease provides a timely review of the impact of rhinovirus infections on human health. It identifies disease mechanisms relating to the virus, human host and environmental factors. This viewpoint allows us to look forward to the development of treatments for a virus for which treatment options are currently non-existent. By providing detailed insights into this virus, its host and the environmental factors that play into rhinovirus induced diseases, this book explains disease mechanisms and summarizes existing and developing therapeutic approaches for better research, diagnosis and potential treatments.

    • Endocrine Secrets

      • 7th Edition
      • August 7, 2019
      • Michael T. McDermott
      • Michael T. McDermott
      • English
      • Paperback
        9 7 8 0 3 2 3 6 2 4 2 8 2
      For more than 30 years, the highly regarded Secrets Series® has provided students and practitioners in all areas of health care with concise, focused, and engaging resources for quick reference and exam review. Endocrine Secrets, 7th Edition, features the Secrets’ popular question-and-answer format that also includes lists, tables, pearls, memory aids, and an easy-to-read style – making inquiry, reference, and review quick, easy, and enjoyable.

    • Nucleic Acid Sensing and Immunity, Part A

      • 1st Edition
      • Volume 344
      • February 22, 2019
      • English
      • Hardback
        9 7 8 0 1 2 8 1 5 9 7 9 8
      • eBook
        9 7 8 0 1 2 8 1 5 9 8 0 4
      Nucleic Acid Sensing and Immunity - PART A, Volume 344, provides a comprehensive overview of the nucleic acid machinery, from plants to mammalians, as well as their regulation. Specific chapters in this updated release include Molecular bases of discrimination between self from non-self nucleic acids, Intracellular RNA sensing in mammalian cells, Nuclear DNA damage and nucleic acid sensing, Negative regulation of nucleic acid sensing, Dendritic cell responses to exogenous nucleic acids, Activating the nucleic acid-sensing machinery for anticancer immunity, and Nucleic acid sensing and inflammasomes, amongst other topics.

    • Immunobiology of Dendritic Cells Part B

      • 1st Edition
      • Volume 349
      • November 22, 2019
      • English
      • Hardback
        9 7 8 0 1 2 8 1 8 3 5 7 1
      • eBook
        9 7 8 0 1 2 8 1 8 3 5 8 8
      Immunobiology of Dendritic Cells Part B, Volume 349 in the International Review of Cell and Molecular Biology series highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

Related subjects

Biochemistry biophysics

Biotechnology

Endocrinology

Life sciences general

Molecular biology cellular biology and genetics

Physiology