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Elsevier

Books in Human physiology

  • Heart Development and Regeneration

    • 1st Edition
    • Nadia Rosenthal + 1 more
    • English
    The development of the cardiovascular system is a rapidly advancing area in biomedical research, now coupled with the burgeoning field of cardiac regenerative medicine. A lucid understanding of these fields is paramount to reducing human cardiovascular diseases of both fetal and adult origin. Significant progress can now be made through a comprehensive investigation of embryonic development and its genetic control circuitry. Heart Development and Regeneration, written by experts in the field, provides essential information on topics ranging from the evolution and lineage origins of the developing cardiovascular system to cardiac regenerative medicine. A reference for clinicians, medical researchers, students, and teachers, this publication offers broad coverage of the most recent advances. Volume One discusses heart evolution, contributing cell lineages; model systems; cardiac growth; morphology and asymmetry; heart patterning; epicardial, vascular, and lymphatic development; and congenital heart diseases. Volume Two includes chapters on transcription factors and transcriptional control circuits in cardiac development and disease; epigenetic modifiers including microRNAs, genome-wide mutagenesis, imaging, and proteomics approaches; and the theory and practice of stem cells and cardiac regeneration.

  • Chesley's Hypertensive Disorders in Pregnancy

    • 3rd Edition
    • James M. Roberts + 2 more
    • English
    Hypertensive disorders remain one the major causes of maternal and fetal morbidity and death. It is also a leading cause of preterm birth now known to be a risk factor in remote cardiovascular disease. Despite this, the hypertensive disorders remain marginally studied, and their management is commonly controversial. Chesley’s Hypertensive Disorders in Pregnancy remains one of the beacons to guide this field, recognized for its uniqueness and utility. The Third Edition continues this tradition, focusing on prediction, prevention, and management for clinicians, and is an essential reference text for clinical and basic investigators alike. Differing from other texts devoted to preeclampsia, it covers the whole gamut of high blood pressure, not just preeclampsia.

  • Molecular Pathology

    The Molecular Basis of Human Disease
    • 1st Edition
    • William B. Coleman + 1 more
    • English
    Molecular Pathology: The Molecular Basis of Human Disease provides a current and comprehensive view of the molecular basis and mechanisms of human disease. Combining accepted principles with broader theoretical concepts and with contributions from a group of experts, the book looks into disease processes in the context of traditional pathology and their implications for translational molecular medicine. It also discusses concepts in molecular biology and genetics, recent scientific and technological advances in modern pathology, the concept of ""molecular pathogenesis"" of disease, and how disease evolves from normal cells and tissues due to perturbations in molecular pathways. The book describes the integration of molecular and cellular pathogenesis using a bioinformatics approach and a systems biology approach to disease pathogenesis. It also discusses current and future strategies in molecular diagnosis of human disease, and the impact of molecular diagnosis on treatment decisions and the practice of personalized medicine. This book is a valuable resource for students, biomedical researchers, practicing physician-scientists who undertake disease-related basic science and translational research, and pathology residents and other postdoctoral fellows.

  • Genetic Diseases of the Kidney

    • 1st Edition
    • Richard P. Lifton + 3 more
    • English
    Genetic approaches have revolutionized our understanding of the fundamental causes of human disease by permitting the identification of specific genes in which variation causes or contributes to susceptibility to, or protection from, disease. More than 2,000 disease genes have been identified in the last 20 years, providing important new insight into the pathophysiology of diseases in every field of medicine. Genetic Diseases of the Kidney offers expert insight into the role of genetic abnormalities in the pathogenesis of abnormal kidney function and kidney disease. Genetic abnormalities are carefully presented within the appropriate physiologic context so that readers will understand not only which genes are linked to which diseases but also which pathways lead from a genetic “disturbance” to the systemic appearance of disease.

  • Textbook of Nephro-Endocrinology

    • 1st Edition
    • Ajay K. Singh + 1 more
    • English
    The Textbook of Nephro-Endocrinology is the definitive translational reference in the field of nephro-endocrinology... investigating both the endocrine functions of the kidneys and how the kidney acts as a target for hormones from other organ systems. It offers researchers and clinicians expert, gold-standard analyses of nephro-endocrine research and translation into the treatment of diseases such as anemia, chronic kidney disease (CKD), rickets, osteoporosis, and, hypoparathyroidism.

  • Hematopathology

    Morphology, Immunophenotype, Cytogenetics, and Molecular Approaches
    • 1st Edition
    • Faramarz Naeim + 2 more
    • English
    This comprehensive, full color hematopathology reference book emphasizes immunophenotpic features, cytogenetic studies, and diagnostic molecular aspects. Hematopathology begins with introductions to morphologic evaluation of the hematopoietic tissues and principles of immunophenotyping, cytogenetics and molecular studies followed by chapters dedicated to different types of hematologic disorders. Each chapter starts with a basic overview of hematopathlogy followed by a comprehensive review of immunophenotypic, cytogenetic and molecular findings. The text is balanced with large numbers of full color images, graphs, charts, and tables to assist the reader in understanding these highly technical issues.

  • Venous Ulcers

    • 1st Edition
    • John J. Bergan + 1 more
    • English
    One of the only books discussing new advances in venous ulcer therapy, Venous Ulcers provides a comprehensive look at the molecular biology and pathophysiology of venous ulcers. It discusses the many new treatments currently being used that offer non-invasive treatment options to patients with venous ulcerations.

  • The Vein Book

    • 1st Edition
    • John J. Bergan
    • English
    The Vein Book is a comprehensive reference on veins and venous circulation. In one volume it provides complete, authoritative, and up-to-date information about venous function and dysfunction, bridging the gap between clinical medicine and basic science. It is the single authoritative resource which consolidates present knowledge and stimulates further developments in this rapidly changing field.

  • Platelets

    • 2nd Edition
    • Alan D. Michelson
    • Alan D. Michelson
    • English
    Platelets, Second Edition is the definitive current source of state-of-the-art knowledge about platelets and covers the entire field of platelet biology, pathophysiology, and clinical medicine. Recently there has been a rapid expansion of knowledge in both basic biology and the clinical approach to platelet-related diseases including thrombosis and hemorrhage. Novel platelet function tests, drugs, blood bank storage methods, and gene therapies have been incorporated into patient care or are in development. This book draws all this information into a single, comprehensive and authoritative resource.

  • Hypothalamic Integration of Energy Metabolism

    • 1st Edition
    • Volume 153
    • A. Kalsbeek + 5 more
    • English
    The prevalence of obesity in developed countries is fast becoming a health issue on par with infectious diseases and malnutrition. Research in this area has grown substantially and includes the neurochemical pathways of the hypothalamus and its role in regulating energy expenditures in the body. This volume in the Progress in Brain Research series examines the emerging role of the hypothalamus as a crucial link between the sensing of nutrients and the control of insulin sensitivity, glucose uptake, and glucose production, the integrative role of the hypothalamus in thyroid and bone metabolism, the interaction between circadian information and energy metabolism, and the important interplay between the immune system and energy metabolism.