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Elsevier

Books in Genomics and proteomics

  • Artificial Intelligence in Livestock Omics

    Applications, Challenges, and Future Perspectives
    • 1st Edition
    • Navid Ghavi Hossein-Zadeh
    • English
    Artificial Intelligence in Livestock Omics: Applications, Challenges, and Future Perspectives delves into the cutting-edge intersection of AI and livestock science, exploring how advanced algorithms are transforming the analysis and application of omics data in livestock production. This book addresses the convergence of AI and biotechnology, highlighting how these fields are not only transforming livestock farming but also contributing to broader goals within personalized medicine, genetic improvement, and the development of resilient animal breeds. Sections provide readers with practical insights, real-world case studies, and a forward-looking perspective on the future of AI-driven livestock management.The integration of AI with omics technologies can also aid in global efforts to improve food security, animal welfare, and sustainable agricultural practices. Whether a researcher, industry professional, or policymaker, this book offers valuable tools and strategies to enhance precision farming, improve animal health, and drive sustainable agriculture in the digital age.

  • Protein Misfolding in Neurodegenerative Diseases

    • 1st Edition
    • Neha Gogia + 2 more
    • English
    Protein Misfolding in Neurodegenerative Diseases is a comprehensive review of proteome homeostasis in neurons, and in the brain. Beginning with an introduction on factors involved in the formation and aggregation of misfolded proteins, chapters then discuss the precise cellular and molecular mechanisms involved in these processes and their role in neurodegeneration and disease. Additional topics of focus include protein clearance mechanisms like protein quality control, disease-modifiers, molecular druggable targets, novel therapeutics, and emerging techniques that block or delay disease onset or progression. This volume is relevant for researchers working with neurodegenerative diseases, including Alzheimer's disease, Parkinson’s disease, ALS, Creutzfeldt-Jakob disease, and more.

  • Advances in Physical Organic Chemistry

    • 1st Edition
    • Volume 57
    • English
    Advances in Physical Organic Chemistry, Volume 57 presents the latest reviews of recent work in physical organic chemistry, providing a valuable source of information that is ideal not only for physical organic chemists applying their expertise to both novel and traditional problems, but also for non-specialists across diverse areas who identify a physical organic component in their approach to research. The book's hallmark is its quantitative, molecular level understanding of phenomena across a diverse range of disciplines.

  • Circadian System

    • 1st Edition
    • Volume 137
    • Rossen Donev
    • English
    Circadian System, Volume 137 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters that comprehensively cover Circadian Systems Genes and Their Importance for Human Health, Single nucleotide polymorphisms (SNPs) in circadian genes: Impact on Gene Function and Phenotype, Relationship between circadian rhythm and diseases: sex hormones impact, Advances in circadian clock regulation of reproduction, Disruption of the clock gene expression in central and peripheral circadian oscillators by maternal overnutrition in the Oryctolagus cuniculus, COVID-19 disease management in aspect of Circadian system, and more. Other sections cover Molecular Characterization of Circadian Gene Expression and Its Correlation with Survival Percentage in Colorectal Cancer Patients, Identifying circadian gene signature that estimates overall survival from colon adenocarcinoma, The role of environmental signals in the expression of rhythmic cardiac proteins and their influence on cardiac pathologies, and much more.

  • Control of Cell Cycle and Cell Proliferation

    • 1st Edition
    • Volume 135
    • Rossen Donev
    • English
    Control of Cell Cycle and Cell Proliferation, Volume 135 in the Advances in Protein Chemistry and Structural Biology series, presents chapters on a variety topics, including Exploiting pivotal mechanisms behind the senescence-like cell cycle arrest, Viral infection on through Cell Cycle Regulation, Analyzing drug resistant mutation in CDK4 gene and identification of potential inhibitors through structure based virtual screening approach, Controlling cell proliferation by targeting CDK6 using drug repurposing approach, The role of the nucleolus in regulating cell cycle, Chromatin regulators in DNA replication and genome stability maintenance during S-phase, Role of macrophage in cancer cell progression and targeted immunotherapies, and much more.

  • Regulation of Downstream Targets

    • 1st Edition
    • Volume 134
    • Rossen Donev
    • English
    Regulation of Downstream Targets, Volume 134 in the Advances in Protein Chemistry and Structural Biology series, presents interesting chapters on topics such as Transcriptional regulatory mechanisms and signaling networks in Viral Infections, Identification of potential key genes associated with pathogenesis and prognosis of endometrial cancer based on Integrated Bioinformatics Approaches, Differential regulation of genes in stage IB pancreatic cancer associated with increased risk of metastasis, AMPK-related LKB1-downstream targets, A compilation of bioinformatic approaches to identify novel downstream targets for the detection and prophylaxis of cancer, Protein phosphatases and their targets: Critical determinants of signaling pathway in plants, and more. Other sections cover Calcium decoders and their targets: The holy alliance that regulate cellular responses, Importin alpha family NAAT/IBB domain: functions of a multi-faceted long chameleon sequence, Aurora Kinase A and related downstream molecules: A Potential Network for Cancer Therapy, Emerging Role of Heat Shock Proteins in Cardiovascular Diseases, Function, Structure, Evolution, Regulation and Drug Target Relevance of Arylalkylamine N-acetyltransferase, and Analysis of signaling cascades from myeloma cells treated with pristimerin.

  • Secretory Proteins

    • 1st Edition
    • Volume 133
    • Rossen Donev
    • English
    Secretory Proteins, Volume 133 in the Advances in Protein Chemistry and Structural Biology series highlights new advances in the field, including chapters on Proprotein Convertases regulate trafficking and maturation of key proteins within the secretory pathway, Secretory Proteins in Cancer Diagnosis, Senescent Cells and SASP in Cancer Microenvironment: new approaches in cancer therapy, Autophagy for secretory protein: Therapeutic targets in cancer, Secretory proteins and pathways of secretion of osteosarcoma, Monocyte secretory proteins as drug targets for arresting progression of atherosclerosis, The secretory phenotypes of envenomed cells: insights into venom cytotoxicity, Macromolecules for secretory pathway in SARS-CoV-2 infection, and much more. Other sections cover Exploring the role of secretory proteins in the human infectious diseases diagnosis and therapeutics, Secretory proteins in orchestration of microbial pathogenesis- the curious case of Staphylococcus aureus, Influence of pathological mutations in Aspartylglucosylamin... Deaspartylase causing Aspartylglucosaminur... an in silico approach, and Change in conformational dynamics of Lipase A secretory protein upon mutation causing Wolman disease.

  • Disorders of Protein Synthesis

    • 1st Edition
    • Volume 132
    • Rossen Donev
    • English
    Disorders of Protein Synthesis, Volume 132 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Protein Interaction Networks

    • 1st Edition
    • Volume 131
    • Rossen Donev
    • English
    Protein Interaction Networks, Volume 131 in the Advances in Protein Chemistry and Structural Biology series, highlights new advances in the field, with this new volume presenting interesting chapters written by an international board of authors.

  • Genomic Medicine Skills and Competencies

    • 1st Edition
    • Dhavendra Kumar
    • English
    Genomic Medicine Skills and Competencies discusses core and practical aspects of genetic and genomic education and training for medical field. Many aspects of genomic applications in science, biotechnology, clinical medicine and healthcare require core and specialist knowledge, skills development and competencies for carrying out diverse tasks. Several knowledge-based courses and opportunities for skills and competencies development and assessment are now available and the main required subjects are discussed in this volume. The book focuses on all major aspects of genetic and genomic education training that are currently offered and evaluated and is a valuable resource for researchers, clinicians, physicians, nurses, genetic counselors, bioinformatics technicians, and other professionals who are interested in learning more about such promising field.