Metabolomics and Microbiomics

Personalized Medicine from the Fetus to the Adult

1st Edition - August 25, 2016
Author: Vassilios Fanos
Language: English
Paperback ISBN:
9 7 8 - 0 - 1 2 - 8 0 5 3 0 5 - 8
eBook ISBN:
9 7 8 - 0 - 1 2 - 8 0 5 4 5 0 - 5

Metabolomics and Microbiomics: Personalized Medicine from the Fetus to the Adult encompasses the most recent advances on the usage of metabolomics and microbiome research… Read more

Purchase options

Limited Offer

Save 50% on book bundles

Immediately download your ebook while waiting for your print delivery. No promo code needed.

Institutional subscription on ScienceDirect

Request a sales quote

Metabolomics and Microbiomics: Personalized Medicine from the Fetus to the Adult
encompasses the most recent advances on the usage of metabolomics and microbiome research to improve disease diagnosis and healthcare. Medicine is changing from epidemiologic, descriptive, reductionist, and reactive approaches to individualized, predictive, and holistic ones by applying microbiomics to understand the functionality of the human body.

The book discusses topics such as systems biology approaches, omics technologies, perinatal programming, and personalized medicine. It also discusses the ethical implications of microbiomics research and new pathways of research, such as renal regenerative medicine, gender medicine in perinatology, and animals and the science of healing. The book is a valuable resource for medical professionals and researchers in metabolomics, nutrition, microbiology, and personalized-predictive medicine. The book also will appeal to non-specialized professionals who may take advantage of its captivating and simple language.

Author’s biography
Introduction
1: Medicine centered on the person
- Abstract
- Through the patient’s eyes
- An irresistible evolution in medicine
2: The five great ideas of biology and medicine
- Abstract
- What is life?
- What are we talking about when we speak of the genome?
- The cell, the city of life
- Biochemistry: maximum yield, minimum cost
- Evolution: I change, ergo I survive
- Systems biology: the whole is not equal to the sum of its parts
3: The medicine of the future
- Abstract
- Medicine of the future, beyond all imagination
- DNA is not everything: not even identical twins are identical
- On the new farm… there’s a sheep, a cat, mice
4: The “-omics” technologies
- Abstract
- The new languages of medicine
- -Omics technologies
- Metabolomics: the rebirth of science or Harry Potter magic?
- Dogs, cats, and “electronic noses”
- Metabolomic Pindaric flights: the most important applications of metabolomics
- Evolution that becomes revolution: metabolomics as the generator of hypotheses
- What is at the root of metabolomics? An intriguing discovery
- Scale-free networks
- Network medicine
- Big data and… ten P medicine
5: Perinatal programming
- Abstract
- Are the fetus and the newborn the parents of the adult?
- The womb is more important than the home
- Return to the future: the placenta and perinatal programming
- The mysterious trees of life
- Journey to the center of the uterus: “I was born to replicate myself”
- Metabolic syndrome
- What do we need to know about perinatal planning? Ten golden rules
- Our plasticity is impressive
- Nutrition in pregnancy
- Transgenerational epigenetic inheritance
- Early nutrition and the destiny of the individual
- How we age depends on our fetal lives
- The mTOR protein: a two-faced angel
- Neonatomics and childomics
6: From birth to the miracle of mother’s milk
- Abstract
- Being born: an adrenaline-charged action movie
- Why does delivery begin?
- The first meal is like the first breath (a hymn to mother’s milk)
- The growth of the intestinal cells
- Microbiota of mother’s milk
- Metabolomics of mother’s milk and formula milk
- Multipotent stem cells of mother’s milk
- Mother’s milk with garlic or curry?
- Personalized fortification of milk of mothers who gave preterm birth
7: The fetus, the preterm baby, and the term baby: the good and the not so good
- Abstract
- The “weight” of prematures
- The new inhabitants of the planet Earth: adults who were born with extremely low weight
- Cerebral programming
- Epigenetic factors that influence development of the brain: alcohol, aluminum, prematurity
- Cardiac programming
- Kidney programming
- Neonatal ethics as a paradigm
- The wonderful and active world of the fetus
- The extraordinary world of sound of fetus and neonate
8: We are an ecosystem: in our bodies only one cell out of ten is human
- Abstract
- Brain versus gut: an ongoing war from the Pleistocene to the present
- The brain is a jungle, not a computer
- The brain–gut connection and microbiota: the gut’s revenge?
- The control room of our organism: the neuro-endo-immune supersystem
- Three different enterotypes
- How to change and monitor our enterotype
- Microbiomics and metabolomics
9: Microbiomics: from the clinic... to the chocolate
- Abstract
- From kefir to fecal transplant
- Kidney and microbiomics
- Autism spectrum disorders and microbiomics
- The strange case of the Caesarean section
- We are what we eat
- Bacteria that love chocolate and... Nobel laureates
10: Personalized medicine
- Abstract
- The medicine of complexity
- But is all this ethical?
- The hateful medical protocols
- Usain Bolt and the secret language of destiny
- The “treasure” of our nephrons
11: The new approaches of research
- Abstract
- How the course of research has changed
- Unexpected similarities
- Kidney regenerative medicine
- The new frontiers of research
- Gender medicine in perinatology
- Animals and the science of healing
12: The medical humanities
- Abstract
- The meeting between physician and patient
- Medical humanities: in the halfway land of complexity
- Narrative-based medicine
13: Scientific debate in the Internet age
- Abstract
- Between evidence-based medicine and medicine-based evidence
- Patients as Internauts
14: Messages to take home
- Abstract
Bibliography
Author Index
Subject Index

Life sciences

Physical sciences & Engineering

Social sciences & Humanities

Health